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Blood Vessels: The Vascular System
 Transport blood to the tissues and back
 Carry blood away from the heart
 Arteries
 Arterioles
 Exchanges between tissues and blood
 Capillary beds
 Return blood toward the heart
 Venules
 Veins
Copyright © 2009 Pearson Education, Inc., publishing as Benjamin Cummings
Blood Vessels: The Vascular System - Page 13
Figure 11.9a
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Blood Vessels: Microscopic Anatomy
 Three layers (tunics)
 Tunica intima
 Endothelium
 Tunica media
 Smooth muscle
 Controlled by sympathetic nervous
system
 Tunica externa
 Mostly fibrous connective tissue
Copyright © 2009 Pearson Education, Inc., publishing as Benjamin Cummings
Blood Vessels: The Vascular System - Page 13
Figure 11.9b
Copyright © 2009 Pearson Education, Inc., publishing as Benjamin Cummings
Differences Between Blood Vessels
 Walls of arteries are the thickest
 Lumens of veins are larger
 Larger veins have valves to prevent backflow
 Skeletal muscle “milks” blood in veins toward the
heart
 Walls of capillaries are only one cell layer thick to
allow for exchanges between blood and tissue
Copyright © 2009 Pearson Education, Inc., publishing as Benjamin Cummings
Blood Vessels: The Vascular System
Figure 11.10
Copyright © 2009 Pearson Education, Inc., publishing as Benjamin Cummings
Movement of Blood Through Vessels
 Most arterial blood is pumped by the heart
 Veins use the milking action of muscles to help
move blood
Copyright © 2009 Pearson Education, Inc., publishing as Benjamin Cummings
Major Arteries of System Circulation
 Aorta
 Largest artery in the body
 Leaves from the left ventricle of the heart
Copyright © 2009 Pearson Education, Inc., publishing as Benjamin Cummings
Major Arteries
of Systemic
Circulation
Page 14
Book p. 379
Figure 11.12
Copyright © 2009 Pearson Education, Inc., publishing as Benjamin Cummings
Major Veins of Systemic Circulation
 Superior and inferior vena cava enter the right
atrium of the heart
 Superior vena cava drains the head and arms
 Inferior vena cava drains the lower body
Copyright © 2009 Pearson Education, Inc., publishing as Benjamin Cummings
Major Veins
of Systemic
Circulation
page 15
Book p. 381
Figure 11.13
Copyright © 2009 Pearson Education, Inc., publishing as Benjamin Cummings
Pulse
 Pulse
 Pressure wave of blood
 Monitored at “pressure points” in arteries where
pulse is easily palpated
 Wrist = radial artery
 Neck = carotid artery
 Pulse averages 70–76 beats per minute at rest
 Average = about 72 bpm
Copyright © 2009 Pearson Education, Inc., publishing as Benjamin Cummings
Pulse p. 16, p. 387 book
Figure 11.18
Copyright © 2009 Pearson Education, Inc., publishing as Benjamin Cummings
Blood Pressure
 Measurements by health professionals are made
on the pressure in large arteries
 Systolic —pressure at the peak of ventricular
contraction
 Diastolic —pressure when ventricles relax
 Write systolic pressure first and diastolic last
(120 / 80 mm Hg)
 Pressure in blood vessels decreases as distance
from the heart increases
 Normal BP = 120 / 80 mm Hg
Copyright © 2009 Pearson Education, Inc., publishing as Benjamin Cummings
Comparison of Blood Pressures
in Different Vessels
Figure 11.19
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Measuring Arterial Blood Pressure – Page 13
Page 389 in your book
a.
Shows the brachial
artery used to
measure blood pressure
Figure 11.20a
Copyright © 2009 Pearson Education, Inc., publishing as Benjamin Cummings
Measuring Arterial Blood Pressure
b.
Wrap cuff snugly
around upper arm
& inflate until cuff
pressure exceeds systolic
pressure (at 160 mm Hg).
At this point, blood flow
into arm stops so pulse
can’t be felt or heard.
Figure 11.20b
Copyright © 2009 Pearson Education, Inc., publishing as Benjamin Cummings
Measuring Arterial Blood Pressure
c.
Reduce cuff pressure &
listen with a stethoscope
for first tapping sounds;
this is systolic pressure
Figure 11.20c
Copyright © 2009 Pearson Education, Inc., publishing as Benjamin Cummings
Measuring Arterial Blood Pressure
d.
Reduce cuff pressure
further; pressure at which
sounds disappear is
diastolic pressure
Figure 11.20d
Copyright © 2009 Pearson Education, Inc., publishing as Benjamin Cummings
Blood Pressure: Effects of Factors
 BP is blood pressure
 BP is affected by age, weight, time of day,
exercise, body position, emotional state
 CO is the amount of blood pumped out of the left
ventricle per minute
 PR is peripheral resistance, or the amount of
friction blood encounters as it flows through
vessels
 Narrowing of blood vessels and increased
blood volume increases PR
 BP = CO  PR
Copyright © 2009 Pearson Education, Inc., publishing as Benjamin Cummings
Blood Pressure: Effects of Factors
 Neural factors
 Autonomic nervous system adjustments
(sympathetic division)
 Renal factors
 Regulation by altering blood volume
 Renin—hormonal control
Copyright © 2009 Pearson Education, Inc., publishing as Benjamin Cummings
Blood Pressure: Effects of Factors
 Temperature
 Heat has a vasodilating effect
 Cold has a vasoconstricting effect
 Chemicals
 Various substances can cause increases or
decreases
 Diet
Copyright © 2009 Pearson Education, Inc., publishing as Benjamin Cummings
Factors Determining Blood Pressure
Figure 11.21
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Variations in Blood Pressure
 Normal human range is variable
 Normal = 120/80
 140–110 mm Hg systolic
 80–75 mm Hg diastolic
 Hypotension
 Low systolic (below 110 mm HG)
 Often associated with illness
 Hypertension
 High systolic (above 140 mm HG)
 Can be dangerous if it is chronic
Copyright © 2009 Pearson Education, Inc., publishing as Benjamin Cummings
Heart Beat Sounds – add this to notes
 Lub = Atrioventricular AV valves closing
 Dub = Semilunar valves closing
Copyright © 2009 Pearson Education, Inc., publishing as Benjamin Cummings
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