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Blood Vessels: The Vascular System Transport blood to the tissues and back Carry blood away from the heart Arteries Arterioles Exchanges between tissues and blood Capillary beds Return blood toward the heart Venules Veins Copyright © 2009 Pearson Education, Inc., publishing as Benjamin Cummings Blood Vessels: The Vascular System - Page 13 Figure 11.9a Copyright © 2009 Pearson Education, Inc., publishing as Benjamin Cummings Blood Vessels: Microscopic Anatomy Three layers (tunics) Tunica intima Endothelium Tunica media Smooth muscle Controlled by sympathetic nervous system Tunica externa Mostly fibrous connective tissue Copyright © 2009 Pearson Education, Inc., publishing as Benjamin Cummings Blood Vessels: The Vascular System - Page 13 Figure 11.9b Copyright © 2009 Pearson Education, Inc., publishing as Benjamin Cummings Differences Between Blood Vessels Walls of arteries are the thickest Lumens of veins are larger Larger veins have valves to prevent backflow Skeletal muscle “milks” blood in veins toward the heart Walls of capillaries are only one cell layer thick to allow for exchanges between blood and tissue Copyright © 2009 Pearson Education, Inc., publishing as Benjamin Cummings Blood Vessels: The Vascular System Figure 11.10 Copyright © 2009 Pearson Education, Inc., publishing as Benjamin Cummings Movement of Blood Through Vessels Most arterial blood is pumped by the heart Veins use the milking action of muscles to help move blood Copyright © 2009 Pearson Education, Inc., publishing as Benjamin Cummings Major Arteries of System Circulation Aorta Largest artery in the body Leaves from the left ventricle of the heart Copyright © 2009 Pearson Education, Inc., publishing as Benjamin Cummings Major Arteries of Systemic Circulation Page 14 Book p. 379 Figure 11.12 Copyright © 2009 Pearson Education, Inc., publishing as Benjamin Cummings Major Veins of Systemic Circulation Superior and inferior vena cava enter the right atrium of the heart Superior vena cava drains the head and arms Inferior vena cava drains the lower body Copyright © 2009 Pearson Education, Inc., publishing as Benjamin Cummings Major Veins of Systemic Circulation page 15 Book p. 381 Figure 11.13 Copyright © 2009 Pearson Education, Inc., publishing as Benjamin Cummings Pulse Pulse Pressure wave of blood Monitored at “pressure points” in arteries where pulse is easily palpated Wrist = radial artery Neck = carotid artery Pulse averages 70–76 beats per minute at rest Average = about 72 bpm Copyright © 2009 Pearson Education, Inc., publishing as Benjamin Cummings Pulse p. 16, p. 387 book Figure 11.18 Copyright © 2009 Pearson Education, Inc., publishing as Benjamin Cummings Blood Pressure Measurements by health professionals are made on the pressure in large arteries Systolic —pressure at the peak of ventricular contraction Diastolic —pressure when ventricles relax Write systolic pressure first and diastolic last (120 / 80 mm Hg) Pressure in blood vessels decreases as distance from the heart increases Normal BP = 120 / 80 mm Hg Copyright © 2009 Pearson Education, Inc., publishing as Benjamin Cummings Comparison of Blood Pressures in Different Vessels Figure 11.19 Copyright © 2009 Pearson Education, Inc., publishing as Benjamin Cummings Measuring Arterial Blood Pressure – Page 13 Page 389 in your book a. Shows the brachial artery used to measure blood pressure Figure 11.20a Copyright © 2009 Pearson Education, Inc., publishing as Benjamin Cummings Measuring Arterial Blood Pressure b. Wrap cuff snugly around upper arm & inflate until cuff pressure exceeds systolic pressure (at 160 mm Hg). At this point, blood flow into arm stops so pulse can’t be felt or heard. Figure 11.20b Copyright © 2009 Pearson Education, Inc., publishing as Benjamin Cummings Measuring Arterial Blood Pressure c. Reduce cuff pressure & listen with a stethoscope for first tapping sounds; this is systolic pressure Figure 11.20c Copyright © 2009 Pearson Education, Inc., publishing as Benjamin Cummings Measuring Arterial Blood Pressure d. Reduce cuff pressure further; pressure at which sounds disappear is diastolic pressure Figure 11.20d Copyright © 2009 Pearson Education, Inc., publishing as Benjamin Cummings Blood Pressure: Effects of Factors BP is blood pressure BP is affected by age, weight, time of day, exercise, body position, emotional state CO is the amount of blood pumped out of the left ventricle per minute PR is peripheral resistance, or the amount of friction blood encounters as it flows through vessels Narrowing of blood vessels and increased blood volume increases PR BP = CO PR Copyright © 2009 Pearson Education, Inc., publishing as Benjamin Cummings Blood Pressure: Effects of Factors Neural factors Autonomic nervous system adjustments (sympathetic division) Renal factors Regulation by altering blood volume Renin—hormonal control Copyright © 2009 Pearson Education, Inc., publishing as Benjamin Cummings Blood Pressure: Effects of Factors Temperature Heat has a vasodilating effect Cold has a vasoconstricting effect Chemicals Various substances can cause increases or decreases Diet Copyright © 2009 Pearson Education, Inc., publishing as Benjamin Cummings Factors Determining Blood Pressure Figure 11.21 Copyright © 2009 Pearson Education, Inc., publishing as Benjamin Cummings Variations in Blood Pressure Normal human range is variable Normal = 120/80 140–110 mm Hg systolic 80–75 mm Hg diastolic Hypotension Low systolic (below 110 mm HG) Often associated with illness Hypertension High systolic (above 140 mm HG) Can be dangerous if it is chronic Copyright © 2009 Pearson Education, Inc., publishing as Benjamin Cummings Heart Beat Sounds – add this to notes Lub = Atrioventricular AV valves closing Dub = Semilunar valves closing Copyright © 2009 Pearson Education, Inc., publishing as Benjamin Cummings