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1. During the winter Lake Michigan freezes over trapping the living organisms under a sheet of solid ice. As the temperature drops the hydrogen bonds between water molecules get locked into a crystalline lattice. Which of the following can be attributed to the fact that the bottom of the lake doesn't freeze solid? A) Water expands as it solidifies making ice water less dense than liquid water. B) Hydrogen bonds are constantly breaking and reforming. C) The organisms' metabolic activity produces enough heat to prevent solidification. D) The solutes distributed in the lake have a higher freezing point. E) The hydration shell surround the ice prevents it from extending past the surface. 2. Which of the following characteristics of water contribute to capillary action in the xylem of plants? A) B) C) D) E) Surface tension Cohesion High boiling point High heat of vaporization Ionic bonds 3. Which of the following is directly responsible for water being liquid at room temperature? A) B) C) D) E) Covalent bonds are weaker than hydrogen bonds Water has a high heat capacity Hydrogen bonds link water molecules together Water is a universal solvent Water is stable due to strong covalent bonds 5. Which are formed through dehydration synthesis? A) 1 only C) 1 and 4 only E) 3 and 4 only B) 4 only D) 2 and 3 only 6. All of the following are organic compounds EXCEPT A) lactic acid C) ethanol E) fats B) water D) proteins 7. Each of the following are properties of water EXCEPT A) B) C) D) E) it has a low heat of vaporization it expands when it freezes it is a useful solvent it has cohesive properties it has a high specific heat 8. All of the following are properties of water EXCEPT A) B) C) D) E) water is an excellent solvent water has a high heat capacity water has low surface tension water adheres to other molecules as water freezes it becomes less dense than its liquid form 9. Humans cannot digest which of the following carbohydrates? A) Fructose C) Cellulose E) Sucrose B) Glucose D) Glycogen 10. Base your answer to the following question on the glucose molecule depicted below. Base your answer to questions 4 and 5 on the molecules depicted below. If the glucose molecule depicted above reacted with a similar molecule with the H + and OH – groups switched on carbon 1, they would bond with a 4. The main component of sex hormones is A) 1 only B) 2 only C) 3 only D) 4 only E) 5 only A) B) C) D) E) – ester bond – glycosidic linkage – saccharidic bond – ester bond – glycosidic linkage 11. Which of the following molecules is correctly paired with its function? 18. Base your answer to the following question on the diagram below. A) glycogen – energy storage in plants B) cellulose – main component of insect exoskeletons C) chitin – withstands turgor pressure in Fungi cell walls D) amylose - energy reserve stored in animal liver E) lignin - main component in Moneran cell walls 12. Starch and glycogen both I. serve as energy storage for organisms II. provide structure and support III. are structural isomers of glucose A) I only C) I and II only E) I, II and III B) II only D) I and III only 13. Which of the following is a similarity between starch and glycogen? A) B) C) D) E) Both are glucose polymers. Both are disaccharides of glucose. Both are stored in animals. Neither provide structure and support. There are no similarities between the molecules. 14. The monosaccharide products of hydrolysis of a molecule of lactose are A) B) C) D) E) maltose and glucose maltose and galactose glucose and galactose glucose and sucrose two molecules of galactose 15. In mammals, carbohydrates are stored mainly as A) maltose C) galactose E) fructose B) glucose D) glycogen 16. The empirical formula for monosaccharides is A) CnH 2nO n C) C2nHnOn E) CnHnO2n B) CnHnOn D) C2nHnO2n 17. Lactose is A) a disaccharide B) a monosaccharide C) a polysaccharide D) an oligosaccharide E) stored in plant cells Which of the following is responsible for forming the bonds that cause the tertiary structure of a protein? A) 1 B) 2 C) 3 D) 4 E) 5 19. The formation of a peptide bond requires a reaction between A) B) C) D) E) carbonyl and amide groups carboxyl and amino groups carbohydryl and amide groups nitryl and amino groups nitro and amino groups 20. The monomer responsible for the formation of sulfide bonds in polypeptides is A) cysteine C) threonine E) none of the above B) methionine D) valine Base your answer to questions 21 and 22 on the diagrams of organic molecules below. 21. This lipid maintains the fluidity in cell membranes. 22. Pepsin, an enzyme in the stomach works on this molecule. 23. The protein albumin can be denatured by all of the following EXCEPT A) B) C) D) E) enzyme concentration heat pH chemical hydrolysis 24. Triglycerides are composed of A) B) C) D) E) Glycerol and one fatty acid Glycerin and two fatty acids Glycerol and three fatty acids Glycerin and three fatty acids Glycogen and three fatty acids 25. The phase in which a lipid exists at room temperature is determined by A) B) C) D) E) the number of fatty acid chains it contains the number of hydrogens it contains the number of double bonds it contains the presence of phosphate the presence of sulfur 26. The diagram above depicts the formation of I. an ester bond II. a glyceride bond III. a triglyceride A) I only B) II only C) I and II only 27. In water, lipids naturally form droplets or a film because of A) B) C) D) E) anti-hydrogen forces hydrophilic interactions hydrophobic interactions ionic bonds van der Waals forces 28. Glycerol is essential for which of the following? A) Lipid synthesis B) The breakdown of glucagon C) The storage of carbohydrates in animal muscle cells D) Alcoholic fermentation E) Nitrogenous base formation 29. DNA is the polymer for which class of compounds? A) Nucleic acids C) Proteins E) Genes B) RNA D) Amino acids 30. All of the following are characteristic of nucleotides EXCEPT A) they are composed of a nitrogenous base, a five-carbon sugar, and a phosphate group B) they are joined by phosphodiester bonds C) the nitrogenous bases include the purines, adenine and guanine, and the pyrimidines, cytosine and thymine D) the nitrogenous bases include the purines, adenine and cytosine, and the pyrimidines, guanine and uracil E) they are joined double bonds D) I and III only E) I, II and III 31. A sample of double-stranded DNA has equal numbers of A) B) C) D) E) adenine nucleotides and guanine nucleotides adenine nucleotides and cytosine nucleotides cytosine nucleotides and thymine nucleotides purines and pyrimidines thymine and uracil molecules Base your answer to questions 32 and 33 on the following diagram: 32. The molecule depicted above is a A) B) C) D) E) DNA adenosine nucleoside DNA adenosine nucleotide RNA adenosine nucleoside RNA adenosine nucleotide RNA adenosine phosphate 33. The above molecule can be found in I. nucleolus II. rough endoplasmic reticulum III. smooth endoplasmic reticulum A) I only C) I and II only E) I, II and III B) II only D) II and III only 34. Which of the following nucleotides is not present in DNA? A) Adenine C) Thymine E) Cytosine 41. Base your answer to the following question on the graph below. B) Guanine D) Uracil 35. Adenine is found in which of the following two compounds? A) B) C) D) E) RNA and ADP Chlorophyll and vitamin A Mitochondria and protein Protein and carbohydrate Vitamins and carbohydrates The reaction labeled B is Base your answer to questions 36 and 37 on the following diagram: A) B) C) D) E) endergonic and catalyzed endergonic and uncatalyzed exergonic and catalyzed exergonic and uncatalyzed irreversible and spontaneous 42. Base your answer to the following question on the free energy diagram below. 36. The activation energy of the above reaction is indicated by A) 1 B) 2 C) 3 D) 4 E) 5 37. The activation energy of the reverse reaction is indicated by A) 1 B) 2 C) 3 D) 4 E) 5 The G of this reaction is A) a B) b C) c D) a + c E) b + c 43. Hydrolysis, the splitting of a molecule via the addition of a molecule of water, is an example of what type of 38. The activation energy of a reaction can be altered by the reaction? addition of A) An exergonic reaction A) substrates B) heat energy B) An endergonic reaction C) enzymes D) ATP C) A condensation reaction E) ADP D) Dehydration synthesis 39. In which of the following reaction types is the E) A hydrophobic reaction activation energy of the forward reaction greater than 44. A reaction in which synthetic chemical activity the activation energy of the reverse reaction? produces a more highly ordered chemical organization A) Exothermic B) Endothermic and a higher free energy state is called: C) Displacement D) Combination A) chemiosmosis B) catabolism E) None of the above C) anabolism D) photolysis 40. The process of dehydration synthesis is both E) electron transport A) anabolic and endergonic B) anabolic and exergonic C) catabolic and endergonic D) catabolic and exergonic E) none of the above 45. All of the following are functions of an allosteric enzyme EXCEPT A) the binding of a substrate may stabilize the active conformation B) the allosteric site serves as the active site in the presence of competitive inhibitors C) the binding of a substrate may stabilize the inactive conformation D) they control key reactions in metabolic pathways E) their activity changes in response to fluctuating concentrations of regulators Base your answer to questions 46 through 49 on the molecules depicted below. 46. Compound known as a thiol A) A B) B C) C D) D E) E D) D E) E 47. May form the high energy bond found in ATP A) A B) B C) C 48. Placement of the functional group determines whether the molecule is a ketone or an aldehyde A) A B) B C) C D) D E) E D) D E) E 49. Contains group that attaches to the 5’ end of a DNA nucleotide A) A B) B C) C 50. Base your answer to the following question on the picture below. 54. Mitochondria are thought to be descendants of endosymbiotic bacterial cells. Which of the following statements best supports this statement? A) Mitochondria and bacteria possess different ribosomes and DNA. B) Mitochondria and bacteria possess similar ribosomes and DNA. C) Both mitochondria and bacteria have cristae. D) Neither mitochondria nor bacteria possess chloroplasts. E) Glycolysis occurs in both mitochondria and bacteria. Indicate the structure(s) thought to be descendant of endosymbiotic bacterial cells. A) A only C) A and C E) B and C B) C only D) A and B 51. Chloroplasts of eukaryotes evolved from which of the following? A) B) C) D) E) Cyanobacteria Photosynthetic prokaryotes Photosynthetic protista Plants Any kind of eukaryote 52. The mitochondria of eukaryotes evolved from what type of organism? A) B) C) D) E) Anaerobic bacteria Aerobic bacteria Euglena Ameoba Any kind of eukaryote 53. Mitochondria and bacteria share which similarities? A) B) C) D) E) They both have similar ribosomes and DNA. They both have cell walls. They both have chromosomes. They both reproduce sexually. There are no similarities. 55. In comparison to plant cell walls, bacterial cell walls contain A) peptidoglycan C) phospholipids E) chitin B) starch D) cellulose 56. Cyanobacteria may contain all of these EXCEPT A) cell membrane C) mitochondria E) ribosomes B) chromatin D) cytochromes 57. Prokaryotes and eukaryotes tend to have which of the following features in common? A) Ribosomes C) Mitochondria E) Lysosomes B) Nuclear membrane D) Golgi apparatus 58. Prokaryotes may contain each of the following structures EXCEPT A) B) C) D) E) lysosomes cell wall cell membrane flagella photosynthetic apparatus 59. A small circle of DNA found outside the main chromosome in bacteria is called a A) pilus C) phage E) plasmid B) retrovirus D) capsid 60. Prokaryotes differ from eukaryotes in that only eukaryotes A) B) C) D) E) include bacteria have ribosomes sized 70S have naked DNA without proteins have a nucleus have flagella which are not constructed of microtubules 61. Person A spends her time at the library on the weekends and refrains from consuming any drugs or alcohol. However, person B consumes a large quantity of alcohol and drugs numerous times a week. Which of the following organelles is responsible for person B's increased tolerance for drugs and alcohol? A) B) C) D) E) Lysosomes Peroxisomes Ribosomes Smooth endoplasmic reticulum Golgi apparatus 62. Which of the following structure-function pairs is matched incorrectly? A) B) C) D) E) Microtubules; muscle contraction Mitochondria; cell respiration Central vacuoles; storage lysosomes; degradation Golgi apparatus; modification 63. Which of the following cytoskeletal elements forms the centrioles within a cell? A) B) C) D) E) Collagen Microtubules Microfilaments Intermediate filaments Pseudopodia 64. In plants, how is the living content connected to adjacent cells? A) Pores C) Plasmodesmata E) Desmosomes B) Tight junctions D) Gap junctions 65. Microfilaments, such as actin, differ from intermediate filaments because microfilaments A) B) C) D) E) maintain the cell shape form the nuclear lamina anchor the nucleus and other organelles function in cell motility have a greater diameter 66. Proteins made by free ribosomes will most likely function in which of the following locations? A) B) C) D) E) Endoplasmic reticulum Plasma membrane Lysosomes Cytosol Nucleus 67. Which of the following would occur if the nucleolus was removed from the cell? A) The nucleus would not divide. B) The rough endoplasmic reticulum would not remain attached to the nuclear lamina. C) Ribosomal RNA would not be synthesized and assembled with proteins. D) DNA would replicate uncontrollably. E) The mRNA would have to be made in the cytoplasm. 68. Besides the nucleus, where is genetic material located within a cell? A) B) C) D) E) mitochondria and chloroplasts ribosomes and rough endoplasmic reticulum lysosomes and Golgi apparatus centrosome and plasmodesmata peroxisome and ribosomes 69. Chloroplasts are mostly located in what part of the plant cell? A) Mitochondria C) Mesophyll tissue E) Grana B) Chlorophyll D) Upper epidermis 70. Alcohol is detoxified in A) B) C) D) E) lysosomes peroxisomes rough endoplasmic reticulum smooth endoplasmic reticulum none of the above 71. Lysosomes operate within the cell by A) metabolizing food within the cytoplasm B) entering the endoplasmic reticulum to metabolize proteins C) fusing with vacuoles to catalyze food and dead organelles D) acting as a defense mechanism for DNA outside the nucleus E) none of the above Base your answer to questions 72 through 74 on the following choices. Select the choice that best fits the description given. Each choice may be used once, more than once, or not at all within this group. ( A ) Cilia and Flagella ( B ) Dynein ( C ) Intermediate Filaments ( D ) Microfilaments ( E ) Tropomyosin 72. Responsible for cytoplasmic streaming in plant cells A) A B) B C) C D) D E) E D) D E) E 73. Hold organelles in place A) A B) B C) C 74. Undergo rotating or undulating motion A) A B) B C) C D) D E) E 75. During the creation of a secretory protein, a vacuole will travel which of the following pathways? A) nucleolus — Golgi apparatus — ribosome — plasma membrane B) nucleus — RER — Golgi apparatus — plasma membrane C) nucleus — RER — lysosome — plasma membrane D) plasma membrane — SER — ribosome — nucleus E) ribosome — Golgi apparatus — nucleolus — plasma membrane 76. Programmed cell death is known as A) anabolism C) catalysis E) denaturation B) apoptosis D) decomposition 77. A cell at equilibrium with its environment is A) hypertonic C) isobaric E) isotonic B) hypotonic D) isochoric 78. A cell with a cytoplasmic solute concentration that is lower than its environment is said to be A) hydrophilic C) hypotonic E) isomorphic B) hypertonic D) isotonic 79. In the cell, the instructions to make rRNA and ribosome protein is found in the A) B) C) D) E) mitochondria nucleolus peroxisomes and glyoxysomes rough endoplasmic reticulum smooth endoplasmic reticulum 80. Gap junctions between animal cells most closely resemble A) B) C) D) E) G-proteins in fungi plasmodesmata in plants synaptic junctions in humans tight junctions in algae none of the above 81. If the steps by which a molecule is transferred from the nucleus of a cell to the extracellular matrix are as follows: 1-nuclear membrane; 2-vesicle; 3-Golgi apparatus; 4-endoplasmic reticulum, which of the following represents the correct sequence? A) 2-1-3-4 C) 4-3-2-1 E) 1-4-2-3 B) 3-4-2-1 D) 1-4-3-2 82. The organelle which consists of flattened membrane sacs and can be considered the final packaging location for proteins and lipids is the A) B) C) D) E) peroxisome endoplasmic reticulum Golgi apparatus lysosome vacuole 83. Cell surface carbohydrates are important for A) B) C) D) E) cell-cell recognition structural integrity fluidity selectivity of the membrane active transportation 84. Membrane proteins function in all of the following ways EXCEPT A) B) C) D) E) transportation of oxygen signal transduction cell-cell recognition enzymatic activity transportation of ions 85. Cells are held together by keratin patches known as A) adherent junctions C) gap junctions E) plasmodesmata B) desmosomes D) hemisomes 86. Which of the following is NOT a component in an animal cell membrane? A) Nucleotides C) Proteins E) Cholesterol Base your answer to questions 91 and 92 on the image below. B) Carbohydrates D) Microtubules 87. If a Paramecium living in pond water were to lose function of its contractile vacuole, what would be the result? A) It would not be able to consume the proper amount of nutrients. B) It would activate its sodium-potassium pumps. C) It would rapidly undergo mitosis. D) It would fill with water and lyse. E) It would shrink. Base your answer to questions 88 and 89 on the picture below. (Before and after pictures of a cell placed in a particular solution.) 91. What event occurred once the plant cell was placed into solution X? A) B) C) D) E) It became turgid It became hypotonic It lysed It became porous It plasmolyzed 92. Solution X must be A) B) C) D) E) hypertonic to the cell hypotonic to the cell isotonic to the cell distilled H 20 cytosol 88. The cell in picture B is considered A) lysed C) turgid E) water B) impermeable D) flaccid 89. Cell A was placed in a solution that is A) hypertonic C) isotonic E) supertonic B) hypotonic D) flaccid 90. The movement of water out of a cell that results in the collapse of the cell is called A) B) C) D) E) plasmolysis dialysis facilitated diffusion counter-current exchange simple diffusion 93. Which of the following is the direct cause of the conformational change during the sodium-potassium pump? A) B) C) D) E) The expulsion of Na + from the inside of the axon K+ release from the inside of the axon Phosphorylation of ATP Na+ binding to signal proteins A sudden change in the membrane potential 94. The pumps that move Na+/K +, H+/K +, and Ca2+ of skeletal muscle across cell membranes are examples of A) B) C) D) E) Active transport Passive transport Facilitated diffusion Ligand-gated channel Exocytosis 95. Base your answer to the following question on the figure below. Without the process indicated in the above figure a cell would NOT be able to A) ingest large materials C) carry out cyclosis E) ingest small materials B) form the plasma membrane D) undergo passive transport 96. Base your answer to the following question on the 5 lettered headings listed below. Select the single heading that most directly applies to the subsequent statement. Each heading may be used once, more than once, or not at all within its group. (A) Receptor-Mediated Endocytosis (B) Exocytosis (C) Phagocytosis (D) Pinocytosis (E) Cotransport An amoeba's pseudopodia wrap around a food particle, engulf it, and package it into a vacuole. Base your answer to questions 97 through 99 on the choices below. (A) Exocytosis (B) Endocytosis (C) Phagocytosis (D) Pinocytosis (E) Receptor-mediated endocytosis 97. Occurs when dissolved substances enter the cell and the plasma membrane folds inward to form a channel allowing the liquid to enter 98. Describes the process of vesicles fusing with the plasma membrane and releasing their contents to the outside of the cell 99. Occurs when specific molecules in the fluid surrounding the cell bind to specialized receptors that concentrate in coated pits in the plasma membrane 100. The structure of ATP most closely resembles that of A) B) C) D) E) acetylcholine adenine nucleoside glutamate thymine nucleotide norepinephrine 101. What is true of aerobic respiration but NOT of anaerobic respiration? A) B) C) D) E) 2 ATP are required for activation. A chemiosmotic gradient is established. Glycolysis is the primary process. Proteins are metabolized. Reduction-oxidation reactions occur. Answer Key Midterm Review 1. A 37. E 73. C 2. B 38. C 74. A 3. C 39. B 75. B 4. E 40. A 76. B 5. C 41. C 77. E 6. B 42. B 78. C 7. A 43. A 79. B 8. C 44. C 80. B 9. C 45. B 81. D 10. E 46. E 82. C 11. C 47. C 83. A 12. A 48. B 84. A 13. A 49. C 85. B 14. C 50. B 86. A 15. D 51. A 87. D 16. A 52. B 88. D 17. A 53. A 89. A 18. D 54. B 90. A 19. B 55. A 91. E 20. A 56. C 92. A 21. A 57. A 93. C 22. D 58. A 94. A A 23. A 59. E 95. 24. C 60. D 96. C 25. C 61. D 97. D 26. D 62. A 98. A 27. C 63. B 99. E 28. A 64. C 100. B 29. A 65. D 101. B 30. D 66. D 31. D 67. C 32. D 68. A 33. C 69. C 34. D 70. D 35. A 71. C 36. B 72. D