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FACT SHEET FOR PATIENTS AND FAMILIES Kidney Disease, High Blood Pressure, and Urine Proteins How is high blood pressure linked to kidney disease? Normal blood pressure is less than 120 “over” 80 (120/80). For most people, if the top number (systolic) is more than 140 or the bottom number (diastolic) is more than 90 (140/90), it’s considered high blood pressure (hypertension). If you have kidney disease, your target will probably be lower because blood pressure affects the kidneys. Your doctor will work with you to set a blood pressure goal based on your age and whether you have certain proteins in your urine. For most kidney patients, the goal is below about 140/90. High blood pressure can cause kidney disease. High urine proteins is a sign that your kidneys aren’t working properly. It can get worse over time. Controlling your blood pressure can reduce urine proteins. It can also slow the progress of kidney disease. You may know that high blood pressure increases your risk of heart disease, heart attack, or stroke. But high blood pressure is also linked to your kidneys. •• High blood pressure is a common cause of kidney disease — and it can make kidney disease worse over time. High blood pressure damages the blood vessels in your kidneys, which keeps them from filtering your blood correctly. •• High blood pressure can increase urine proteins. If the “pipes” in your kidneys are leaking, high blood pressure puts force on the leaks. This force causes more protein to pass through — and can make the leaks themselves worse. •• Kidney disease can increase your blood pressure. When your kidneys can’t properly filter the fluids in your body, your blood pressure rises. How can I help control high blood pressure and urine proteins? How are urine proteins linked to high blood pressure and kidney disease? By keeping your blood pressure low, you can reduce the protein in your urine and slow the progression of kidney disease. You can do this by following the MAWDS plan: Your doctor checks proteins in your urine with a urine test. If you have diabetes, you’ll probably have this test every year. Or, depending on your stage of kidney disease, you might need it more often. Urine proteins are linked to kidney disease and high blood pressure: •• High urine proteins are a sign of kidney disease. Healthy kidneys filter waste products into your urine, but leave protein in your body. If you think of the tiny tubes in your kidneys as pipes, urine proteins are a sign that the pipes are leaking. The leaks can increase as your kidney disease progresses. •• M - Take prescribed medication as directed. •• A - Increase your physical activity. •• W - Lose weight, if you’re overweight. •• D - Eat a healthy diet that that’s low in sodium (salt). •• S - Stop smoking and manage stress. To learn more about all of these, turn the page. 1 Manage blood pressure and urine proteins with MAWDS Learn and remember “MAWDS” to help manage your blood pressure and reduce urine proteins. Medication — Take your medication. Taking prescribed medications is extremely important. Make sure you understand how and when to take your medications. See page 3 for information on medications that can lower blood pressure and urine proteins. Activity — Stay active every day. Getting at least 30 minutes of moderate-level aerobic exercise most days can help you lower your systolic blood pressure as much as 9 points. What does “moderate-level aerobic exercise” mean? Aerobic exercise uses large muscle groups, and it’s usually continuous and rhythmic. Examples include biking, brisk walking, swimming, hiking, dancing, and raking leaves. At a moderate level, you breathe a little harder, but aren’t out of breath. Your muscles feel a little fatigued, but they’re not burning from pain. You feel invigorated, but not exhausted. Weight — Maintain a healthy weight. If you’re overweight, losing even a small amount of weight can lower your blood pressure. Studies have shown that if you’re overweight, you can reduce your systolic blood pressure by 2 to 10 points for every 10 pounds that you lose. How can you know whether you’re overweight? A good way to tell is your Body Mass Index (BMI). The BMI formula compares your weight to your height. You can find a BMI calculator at www.nhlbi.nih.gov/guidelines/ obesity/BMI/bmicalc.htm — if your BMI is over 25, you’re overweight. (If you have advanced kidney disease, you might be underweight. In this case it’s important not to lose weight. Check with your healthcare provider.) The best ways to reach and maintain a healthy weight are to be active and follow a healthy eating plan. Intermountain’s Weigh to Health booklet provides advice and encouragement. Diet — Eat a healthy diet that’s low in sodium (salt). Following a healthy eating plan that limits sodium to less than 2,000 mg per day can lower your systolic blood pressure by 2 to 8 points. One study showed that you may be able to reduce your blood pressure after just two weeks! Tips on reducing sodium: First, lose the salt shaker. But reducing sodium means more than just not adding salt. –– Avoid high-sodium foods like canned soups and sauces, macaroni and cheese, pizza, hot dogs, salty snacks, potato salad, pickles, and processed meats (ham, salami, beef jerky). –– Read food labels carefully. Look for foods with sodium content less than 5% Daily Value. Remember to check the serving size; that’s the basis for the sodium value and other nutrition facts. –– Look for “unsalted,” “no salt added,” or “low-sodium” versions of your favorite foods. You may be surprised by how many you can find. –– When you eat out, ask for condiments and dressings “on the side.” Limit salt substitutes. Many salt substitutes are high in potassium. Potassium is a mineral that can build up in your blood if you have kidney disease and lead to other health problems. Instead of salt substitutes, consider using lemon, herbs, and herb seasoning mixes (such as Mrs. Dash). Smoking and Stress — Stop smoking and manage stress. Tobacco harms your arteries and increases your blood pressure. Chronic stress can also take a toll on your body. Quitting smoking — and learning to manage stress — can lower your blood pressure and improve your overall health. Intermountain’s booklet Quitting Tobacco: Your Journey to Freedom has information and strategies to help you become tobacco-free for life. 2 Taking blood pressure medication •• Make sure you understand exactly how to take your medications, including when to take them, how much to take, whether to take them with food, and what to do if you miss a dose. •• If you’re concerned about cost, talk to your healthcare provider. There may be a less expensive drug or generic form you can use instead. •• Make your medications part of your daily routine. For example, take them when you brush your teeth. •• Make sure your healthcare providers know what other medications you’re taking. This includes overthe-counter medications or supplements. Sometimes these can interfere with your prescription medications. •• Plan ahead for refills. Many doctor’s offices won’t refill medications on weekends. Always make sure you have a one-week supply. •• Do NOT stop taking your medications, unless your healthcare provider tells you to. Even if your blood pressure has reached its goal, it may not stay there without your medications. Common blood pressure medications The table below lists the most common categories of blood pressure medication. Your healthcare provider will prescribe the best medications for your unique situation. Category How these medications help Common examples Angiotensin converting enzyme (ACE) inhibitors ACE inhibitors lower blood pressure by helping the blood vessels open wider. They also work directly to reduce urine proteins. ACE inhibitors may cause a cough. If they do, contact your healthcare provider. benazepril, captopril, enalapril, fosinopril, lisinopril, moexipril, perindopril, quinapril, ramipril, trandolapril Angiotensin receptor blockers (ARBs) ARBs also help blood vessels open wider, helping to lower the blood pressure. ARBs also reduce urine proteins. azilsartan, candesartan, eprosartan, irbesartan, losartan, olmesartan, telmisartan, valsartan Diuretics Diuretics (“water pills”) help the kidneys reduce the amount of sodium and water in the body, which reduces blood pressure. Your doctor may prescribe more than one diuretic at a time. bumetanide, chlorthalidone, furosemide, hydrochlorothiazide, metolazone, torsemide Aldosterone receptor antagonists Aldosterone receptor antagonists trigger the kidneys to get rid of unneeded water and sodium through urine. This lowers the volume of blood that the heart must pump, which lowers blood pressure. eplerenone, spironolactone Calcium channel blockers Calcium channel blockers keep calcium from entering the cells of your blood vessels. This helps them open wider so blood pressure goes down. amlodipine, diltiazem, felodipine ER, isradipine, nifedipine ER, verapamil Beta blockers Beta blockers reduce nerve impulses to your heart and blood vessels. This decreases the force of the heartbeat to lower blood pressure. atenolol, bisoprolol, carvedilol, labetalol, metoprolol, metoprolol ER, nadolol, nebivolol, propranolol Alpha blockers Alpha blockers reduce nerve impulses to blood vessels, allowing blood to flow more easily. doxazosin, prazosin, terazosin 3 Monitoring your blood pressure Other Intermountain resources Your healthcare provider may ask you to monitor your blood pressure regularly at home. Monitoring helps you and your healthcare provider see how well lifestyle changes and medications are controlling your blood pressure. This can help fine-tune your treatment plan. The following resources can help you learn more about high blood pressure and control it effectively: Many types of blood pressure monitors are available. You can purchase them at drugstores, supermarket pharmacies, or other large stores. Here are some tips for choosing and using a blood pressure monitor: •• Choose a monitor with a cuff that wraps around the upper arm, and make sure the cuff is the right size. •• BP Basics: This booklet gives you more details on lifestyle changes and other treatments for high blood pressure. •• BP Tracker: This tracker gives you an easy way to record your blood pressure regularly. •• Look for a monitor that also shows your heart rate. •• Try to get readings at a consistent time each day, usually morning or evening. Don’t take your blood pressure within a half hour of eating a heavy meal, using caffeine, exercising, or using tobacco. •• Sit quietly for 5 minutes before taking your blood pressure. It’s also a good idea to take 3 readings about 5 minutes apart. •• If you can, rest your arm on a table or on the arm of a chair, at the level of your heart. Rest both feet flat on the floor. •• Bring your monitor to your doctor’s office visits. Your doctor may check that the monitor readings are similar to your in-office BP checks. This can help you feel more confident about your readings at home. “I loved salt — and salty foods — but I “I didn’t want to take blood pressure I didn’t have any problem. And now that I’m walking every day and I’ve lost some weight, my doctor said I can take a lower dose.” knew my kidneys were worth making some changes in my diet. I thought it would be tough. But I was surprised... my taste buds adjusted pretty fast. Within a few weeks, I didn’t miss the salt as much. And now, when I take a potato chip off my husband’s plate, it tastes way too salty for me.” — Elaine, kidney patient pills because my cousin said he had heard they have a lot of side effects. But my doctor said only 1 in 10 people have annoying side effects, and if that happens, the doctor can change the medication. — Marcos, kidney patient © 2012–2014 Intermountain Healthcare. All rights reserved. The content presented here is for your information only. It is not a substitute for professional medical advice, and it should not be used to diagnose or treat a health problem or disease. Please consult your healthcare provider if you have any questions or concerns. More health information is available at intermountainhealthcare.org. Patient and Provider Publications 801-442-2963 FS315 - 01/14 Also available in Spanish. 4