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Biology I: Cell Growth and Division, Mitosis vs. Meiosis STUDY GUIDE: Biology Textbook: pg. 240 – 253, 275 - 278 Name: ______________________ 1. List two problems that growth causes for cells. ________________________________________________________________________________________ ________________________________________________________________________________________ ________________________________________________________________________________________ 2. Define: A. Cell cycle: ________________________________________________________________________ B. interphase: ________________________________________________________________________ C. cell division: ______________________________________________________________________ D. DNA replication: __________________________________________________________________ 3. Label and describe parts A and B in the following diagram: A: _________________________________________________________________ B: _________________________________________________________________ Define chromatin: ____________________________________________________ What is the name of the entire structure shown in this diagram? ________________ 4. The main events of the cell cycle are labeled A, B, C, and D in Figure 3. Name these events. Then, briefly state what happens during each event. _________________________________________________ __________________________________________________ ___________________________________________________ __________________________________________________ __________________________________________________ __________________________________________________ __________________________________________________ _________________________________________________ __________________________________________________ ___________________________________________________ ___________________________________________________ 5. Define mitosis: _____________________________________________________________________ Name the four phases of mitosis (in order in which they occur) and briefly state the main events that take place during each phase: 1. _________________________________________________________________________________ _______________________________________________________________________ 2. _________________________________________________________________________________ _______________________________________________________________________ 3. _________________________________________________________________________________ _______________________________________________________________________ 4. _________________________________________________________________________________ _______________________________________________________________________ 6. Use the diagrams below to answer the following questions on the lines provided. What do these diagrams represent? How do you know if this is an animal cell or a plant cell? ________________________________________________________ ________________________________________________________ ________________________________________________________ ________________________________________________________ What is the number of chromosomes in the cell shown in the diagram? ____________________________________________________ Identify the structures labeled X and Y. X: _______________________ Y: _______________________ List the correct order for the diagrams: ___________________ After the steps shown in the diagram have been arranged in the correct order, what would a diagram of a final step show? ________________________________________________________________________________________ Define: centriole: ______________________________________________________________________ spindle: ________________________________________________________________________ How does the number of chromosomes in the two new cells compare with the number in the original cell at the end of cell division? ______________________________________________________________ Explain the importance of mitosis in multicellular organisms: ___________________________________ _____________________________________________________________________________________ Explain the importance of mitosis in unicellular organisms: _____________________________________ 7. Define cytokinesis: _____________________________________________________________________ Describe how a plant cell produces a new cell wall during cytokinesis. ______________________________ _____________________________________________________________________________________ How is cytokinesis in animal cells different from cytokinesis in plant cells? ____________________________ _________________________________________________________________________________________ 8. Describe the role of cyclins in the cell cycle: ____________________________________________________ _________________________________________________________________________________________ Describe how the skin cells near a cut behave. What role does contact with other cells have in the behavior of cells near a cut? ________________________________________________________________________________________ ________________________________________________________________________________________ Identify a factor that can stop cells from growing. Give an example of how this factor affects cell growth. _____________________________________________________________________________________________ _____________________________________________________________________________________ 9. Explain how cancer cells are different from normal cells: _________________________________________ _______________________________________________________________________________________ Why can cancer be considered a disease of the cell cycle? _________________________________________ ________________________________________________________________________________________ 10. Complete the following: On the line provided, label each event with one of the four phases of mitosis in which it occurs. A phase may be used more than once. ____________________a. The chromosomes line up across the middle of the cell. ____________________b. Chromosomes become visible. ____________________c. Centrioles separate. ____________________d. Sister chromatids separate into individual chromosomes. ____________________e. Two new nuclear envelopes form. ____________________f. The nucleolus disappears and the nuclear envelope breaks down. ____________________g. Each chromosome is connected to a spindle fiber. ____________________h. The individual chromosomes move apart. 11. True or False If the statement is true, write true. If it is false, write false. _________1. One of two identical “sister” parts of a copied chromosome is called a chromatid. _________2. The final phase of mitosis in which the nuclear envelope re-forms is called anaphase. _________3. Division of the cytoplasm takes place during prophase. _________4. Adisorder in which some of the body’s cells grow uncontrollably is called cancer. _________5. The first phase of mitosis is called prophase. _________6. The part of the cell cycle in which the cell grows and replicates its DNA is interphase. _________7. The third stage of mitosis during which the sister chromatids separate and become individual chromosomes is cytokinesis. _________8. The division of the cell nucleus occurs during interphase. _________9. Atiny structure located in the cytoplasm near the nuclear envelope is a centriole. _________10. The stage of mitosis in which the chromosomes line up across the center of the cell is metaphase. 12. Which pair is correct? a. G1 phase, DNA replication c. S phase, cell division b. G2 phase, preparation for mitosis d. M phase, cell growth 13. Which of the following is a factor that can stop normal cells from growing? a. contact with other cells b. growth factors c. a cut in the skin d. cyclin that has been taken from a cell in mitosis 14. Define: a. meiosis: __________________________________________________________________________________ b. homologous chromosomes: __________________________________________________________________ c. diploid(2n): ________________________________________________________________________________ d. haploid (n) :________________________________________________________________________________ e. crossing over: _____________________________________________________________________________ f. tetrad: ___________________________________________________________________________________ g. gamete: __________________________________________________________________________________ h. sperm: ___________________________________________________________________________________ i. egg: _____________________________________________________________________________________ j. polar bodies: _______________________________________________________________________________ 15. Identifying Processes On the lines provided, order the different stages of meiosis I and meiosis II in the proper sequence. ______________ 1. Spindle fibers pull apart homologous chromosomes. ______________ 2. Four haploid (N) daughter cells form. ______________ 3. Cells undergo a round of DNA replication. ______________ 4. Sister chromatids separate from each other. ______________ 5. Homologous chromosomes form tetrads. ______________ 6. Two haploid (N) daughter cells form. ______________ 7. Spindle fibers attach to the homologous chromosome pairs. ______________ 8. Individual chromatids move to each end of the cell. ______________ 9. Crossing-over (if any) occurs. 16. Compare and contrast the process of mitosis and meiosis: MITOSIS MEIOSIS Number of chromosomes in parent cell? (2n or n) Do chromosomes replicate? (yes or no) Do homologous chromosomes pair up? (yes or no) How many cell divisions? How many daughter cells produced? Number of chromosomes in daughter cells? (n or 2n) Type of cells produced? Where in body does this process take place? 17. If a diploid cell containing 28 chromosomes undergoes meiosis, how many chromosomes will each daughter cell have? ___________ 18. Circle the letter of each sentence that is true about meiosis. a. During meiosis I, homologous chromosomes separate. b. The two daughter cells produced by meiosis I still have the two complete sets of chromosomes, as does a diploid cell. c. During anaphase II, the paired chromatids separate. d. After meiosis II, the four daughter cells contain the diploid number of chromosomes. 19. Why is meiosis described as a process of reduction division? _________________________________________ _____________________________________________________________________________________________