Download Mutations Worksheet

Name
____________ Date: _______________________
Mutations Practice
There are several types of mutations. Complete the boxes below by transcribing and translating the DNA.
Using the Original DNA, mRNA, and Amino acid sequences, classify each Mutated DNA sequences as either: Base
Substitution(missense or silent) OR as either frameshift(deletion or insertion).
Original DNA Sequence:
T A C A C C T T G G C G A C G A C T
mRNA Sequence:
Amino Acid Sequence:
Mutated DNA Sequence #1: T A C G A C C T T G G C G A C G A C T
What’s the mRNA sequence?
(Circle the change)
What will be the amino acid sequence?
Will there likely be effects?
What kind of mutation is this?
Mutated DNA Sequence #2: T A C A C C T T A G C G A C G A C T
What’s the mRNA sequence?
(Circle the change)
What will be the amino acid sequence?
Will there likely be effects?
What kind of mutation is this?
Mutated DNA Sequence #3: T A C A C C T T G G C G A C T A C T
What’s the mRNA sequence?
(Circle the change)
What will be the amino acid sequence?
Will there likely be effects?
What kind of mutation is this?
Mutated DNA Sequence #4: T A C A C C T T G G G A C G A C T
What will be the corresponding mRNA sequence?
What will be the amino acid sequence?
Will there likely be effects?
What kind of mutation is this?
1. Which type of mutation results in abnormal amino acid sequence?
2. Which type of mutation had NO effect on the amino acid sequence?
3.
Which type of mutation(s) is responsible for new variations of a trait?