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University of Illinois Hospital & Health Sciences System Chicago, IL NO.: P 1.40 DATE: September, 2008 REVISED: December, 2011 PAGE: 1 of 3 OBSTETRICS GUIDELINE ____________________________________________________________________________ SUBJECT: PREGNANCY DATING OBJECTIVE 1. To determine accurate pregnancy dating. 2. To identify an agreed upon schema for determining pregnancy dating so that the department agrees on management POSITION STATEMENTS Pregnancy dating will be by ultrasound if clinical dating is uncertain or if there is a discrepancy between clinical dating and ultrasound dates. As ultrasound dating early in pregnancy is very reliable and has a very small margin of error, ultrasound is more accurate. If it is anticipated that highly accurate dating will be important in the pregnancy, an early ultrasound should be obtained and used for dating. Alternatively many patients are having first trimester ultrasound for sequential screening, and this is an opportunity for more accurate dating. As more patients are having infertility treatments, they may have accurate clinical dating by a known ovulation or embryo transfer date. This is the most accurate dating available. Importance of reliable pregnancy dating: A. Avoid iatrogenic newborn prematurity B. Determine when to initiate post term fetal surveillance testing C. Facilitate decisions regarding delivery timing and treatment of preterm labor or preterm premature ruptured membranes. D. Appropriate timing of gestational age-related testing PROCEDURE KEY ACCOUNTABILITIES: 1. The physician/midwife provider will initiate pregnancy dating procedures at the first pregnancy encounter. 2. The physician/midwife provider will evaluate pregnancy dating reliability considering the following evidence based guidelines, documenting adjustments in the pregnancy record: A. Dating will be by ultrasound if clinical dating uncertain University of Illinois Hospital & Health Sciences System Chicago, IL NO.: P 1.40 DATE: September, 2008 REVISED: December, 2011 PAGE: 2 of 3 OBSTETRICS GUIDELINE ____________________________________________________________________________ B. Dating by clinical if infertility patient and date of conception is clear C. Dating will be re-assigned to ultrasound dates from clinical dates (by last menstrual period [LMP]) depending on gestational age and discrepancy between LMP and ultrasound using the general evidence based guidelines in TABLE 1 as follows: [NOTE: Dating changes made after Quad screen performed may require recalculation of prior results.] TABLE 1: Procedure for changing the EDC when the ultrasound and LMP data do not match Dating by Ultrasound 7 0/7 < 9 6/7 wks Difference from LMP (days) ≥ 3 days 10 0/7 - 13 6/7 wks ≥ 5 days If 14 0/7 weeks by LMP and 13 2/7 weeks by ultrasound, re-dating recommended. 14 0/7 – 21 6/7 wks ≥ 7 days If 19 0/7 weeks by LMP and 18 0/7 weeks by ultrasound, re-dating recommended. 22 0/7 – 25 6/7 wks ≥ 10 days If 22 2/7 weeks by LMP and 24 2/7 weeks by ultrasound, re-dating recommended. 26 0/7 - 29 6/7 wks ≥ 14 days If 30 0/7 weeks by LMP and 28 0/7 weeks by ultrasound, re-dating recommended. ≥ 30 wks Example If 7 0/7 weeks by LMP and 7 4/7 weeks by ultrasound, re-dating recommended. ALWAYS re-date with caution. In general, this must be individualized. Need to consider IUGR as an explanation for the discrepancy. Consider re-dating if there is a large difference (i.e. ≥ 3 weeks). REFERENCES: Variability is uniform at 8% for crown rump length [CRL] measurements between 2mm and 12cm: (Hadlock 1992) University of Illinois Hospital & Health Sciences System Chicago, IL NO.: P 1.40 DATE: September, 2008 REVISED: December, 2011 PAGE: 3 of 3 OBSTETRICS GUIDELINE ____________________________________________________________________________ Accuracy of CRL in predicting menstrual age was 3-5 days: Sonar measurement of fetal crown-rump length as means of assessing maturity in first trimester of pregnancy. BMJ 1973;4:281. Robinson HP, Fleming JE. A critical evaluation of sonar "crown rump length" measurements. Br J Obstet Gynaecol 1975;82:702. Drumm JE, Clinch J, MacKenzie G. The ultrasonic measurement of fetal crown-rump length as a method of assessing gestational age. Br Obstet Gyneaecol 1976;83:417 Accuracy of ultrasound in predicting gestational.age is +/- 7 days for 12-18 weeks: Reece EA, Gebrielli S, Degennaro N, et al. Dating through pregnancy: a measure of growing up. Obstet Gynecol Surv. 1989;44:544. Callen, PW. Ultrasonography in Obstetrics and Gynecology; 5th edition, 2008. Hadlock FP, Harrist RB, Martinez-Payer J. How accurate is second trimester fetal dating? J Ultras Med 10:557,1991. Degani S. Fetal biometry: clinical, pathological and technical considerations. Obstet Gynecol Surv 56:159,2001. Chervenak FA, Skupski DW, Romero R, et al. How accurate is fetal biometry in the assessment of fetal age. Am J Obstet Gynecol 178:678,1998. Mongelli M, Wilcox M, Gardosi J. Estimating the date of confinement: Ultrasound biometry versus certain menstrual dates. Am J Obstet Gynecol 174:278,1996 Fleisher A, Toy E, Lee W, Manning F, Romero R. Sonography in Obstetrics and Gynecology: Principles and Practice, 7th Edition, McGraw-Hill, 2011. ______________________________ Judith Hibbard, M.D. Medical Director, Obstetrics Professor, Obstetrics & Gynecology Director, Maternal Fetal Medicine DATE: ______________________________