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Strain Name: C57BL/6J(Stock Number: 000664) http://jaxmice.jax.org/strain/000664.html
References
provided by MGI
Selected Reference(s)
Black BL; Croom J; Eisen EJ; Petro AE; Edwards CL; Surwit RS. 1998. Differential effects of fat and sucrose on body composition in
A/J and C57BL/6 mice. Metabolism 47(11):1354-9. [PubMed: 9826212] [MGI Ref ID J:50965]
Champy MF; Selloum M; Zeitler V; Caradec C; Jung B; Rousseau S; Pouilly L; Sorg T; Auwerx J. 2008. Genetic background
determines metabolic phenotypes in the mouse. Mamm Genome 19(5):318-31. [PubMed: 18392653] [MGI Ref ID J:137669]
Drake TA; Schadt E; Hannani K; Kabo JM; Krass K; Colinayo V; Greaser LE 3rd; Goldin J; Lusis AJ. 2001. Genetic loci determining
bone density in mice with diet-induced atherosclerosis. Physiol Genomics 5(4):205-15. [PubMed: 11328966] [MGI Ref ID J:69682]
Ishida BY; Blanche PJ; Nichols AV; Yashar M; Paigen B. 1991. Effects of atherogenic diet consumption on lipoproteins in mouse
strains C57BL/6 and C3H. J Lipid Res 32(4):559-68. [PubMed: 1856605] [MGI Ref ID J:109926]
Jiao S; Cole TG; Kitchens RT; Pfleger B; Schonfeld G. 1990. Genetic heterogeneity of plasma lipoproteins in the mouse: control of
low density lipoprotein particle sizes by genetic factors. J Lipid Res 31(3):467-77. [PubMed: 1971301] [MGI Ref ID J:15484]
Kirk EA; Moe GL; Caldwell MT; Lernmark JA; Wilson DL; LeBoeuf RC. 1995. Hyper- and hypo-responsiveness to dietary fat and
cholesterol among inbred mice: searching for level and variability genes. J Lipid Res 36(7):1522-32. [PubMed: 7595076] [MGI Ref
ID J:28648]
Nishina PM; Verstuyft J; Paigen B. 1990. Synthetic low and high fat diets for the study of atherosclerosis in the mouse. J Lipid Res
31(5):859-69. [PubMed: 2380634] [MGI Ref ID J:27046]
Paigen B. 1995. Genetics of responsiveness to high-fat and high- cholesterol diets in the mouse. Am J Clin Nutr 62(2):458S-462S.
[PubMed: 7625360] [MGI Ref ID J:28248]
Paigen B; Ishida BY; Verstuyft J; Winters RB; Albee D. 1990. Atherosclerosis susceptibility differences among progenitors of
recombinant inbred strains of mice. Arteriosclerosis 10(2):316-23. [PubMed: 2317166] [MGI Ref ID J:22615]
Paigen B; Morrow A; Brandon C; Mitchell D; Holmes P. 1985. Variation in susceptibility to atherosclerosis among inbred strains of
mice. Atherosclerosis 57(1):65-73. [PubMed: 3841001] [MGI Ref ID J:109950]
Petkov PM; Cassell MA; Sargent EE; Donnelly CJ; Robinson P; Crew V; Asquith S; Haar RV; Wiles MV. 2004. Development of a SNP
genotyping panel for genetic monitoring of the laboratory mouse. Genomics 83(5):902-11. [PubMed: 15081119] [MGI Ref ID
J:89298]
Toye AA; Lippiat JD; Proks P; Shimomura K; Bentley L; Hugill A; Mijat V; Goldsworthy M; Moir L; Haynes A; Quarterman J; Freeman
HC; Ashcroft FM; Cox RD. 2005. A genetic and physiological study of impaired glucose homeostasis control in C57BL/6J mice.
Diabetologia 48(4):675-86. [PubMed: 15729571] [MGI Ref ID J:106692]
Waterston RH; Lindblad-Toh K; Birney E; Rogers J; Abril JF; Agarwal P; Agarwala R; Ainscough R; Alexandersson M; An P;
Antonarakis SE; Attwood J; Baertsch R; Bailey J; Barlow K; Beck S; Berry E; Birren B; Bloom T; Bork P; Botcherby M; Bray N; Brent
MR; Brown DG; Brown SD; Bult C; Burton J; Butler J; Campbell RD; Carninci P; Cawley S; Chiaromonte F; Chinwalla AT; Church DM;
Clamp M; Clee C; Collins FS; Cook LL; Copley RR; Coulson A; Couronne O; Cuff J; Curwen V; Cutts T; Daly M; David R; Davies J;
Delehaun. 2002. Initial sequencing and comparative analysis of the mouse genome. Nature 420(6915):520-62. [PubMed:
12466850] [MGI Ref ID J:80507]
Additional References
Beamer WG; Donahue LR; Rosen CJ; Baylink DJ. 1996. Genetic variability in adult bone density among inbred strains of mice. Bone
18(5):397-403. [PubMed: 8739896] [MGI Ref ID J:33789]
Beamer WG; Shultz KL; Churchill GA; Frankel WN; Baylink DJ; Rosen CJ; Donahue LR. 1999. Quantitative trait loci for bone density
in C57BL/6J and CAST/EiJ inbred mice. Mamm Genome 10(11):1043-9. [PubMed: 10556421] [MGI Ref ID J:58152]
Bultman SJ; Klebig ML; Michaud EJ; Sweet HO; Davisson MT; Woychik RP. 1994. Molecular analysis of reverse mutations from
nonagouti (a) to black-and-tan (a(t)) and white-bellied agouti (Aw) reveals alternative forms of agouti transcripts. Genes Dev
8(4):481-90. [PubMed: 8125260] [MGI Ref ID J:16984]
Bultman SJ; Michaud EJ; Woychik RP. 1992. Molecular characterization of the mouse agouti locus. Cell 71(7):1195-204. [PubMed:
1473152] [MGI Ref ID J:3523]
Chen J; Astle CM; Harrison DE. 2000. Genetic regulation of primitive hematopoietic stem cell senescence. Exp Hematol
28(4):442-50. [PubMed: 10781902] [MGI Ref ID J:61814]
Erway LC; Shiau YW; Davis RR; Krieg EF. 1996. Genetics of age-related hearing loss in mice. III. Susceptibility of inbred and F1
hybrid strains to noise-induced hearing loss. Hear Res 93(1-2):181-7. [PubMed: 8735078] [MGI Ref ID J:33970]
Ewart SL; Kuperman D; Schadt E; Tankersley C; Grupe A; Shubitowski DM; Peltz G; Wills-Karp M. 2000. Quantitative trait loci
controlling allergen-induced airway hyperresponsiveness in inbred mice. Am J Respir Cell Mol Biol 23(4):537-45. [PubMed:
11017920] [MGI Ref ID J:66641]
Freeman HC; Hugill A; Dear NT; Ashcroft FM; Cox RD. 2006. Deletion of Nicotinamide Nucleotide Transhydrogenase: A New
Quantitive Trait Locus Accounting for Glucose Intolerance in C57BL/6J Mice. Diabetes 55(7):2153-6. [PubMed: 16804088] [MGI
Ref ID J:109356]
Hollyfield JG; Bonilha VL; Rayborn ME; Yang X; Shadrach KG; Lu L; Ufret RL; Salomon RG; Perez VL. 2008. Oxidative
damage-induced inflammation initiates age-related macular degeneration. Nat Med :. [PubMed: 18223656] [MGI Ref ID J:129432]
Le AD; Ko J; Chow S; Quan B. 1994. Alcohol consumption by C57BL/6, BALB/c, and DBA/2 mice in a limited access paradigm.
Pharmacol Biochem Behav 47(2):375-8. [PubMed: 8146231] [MGI Ref ID J:17161]
Mekada K; Abe K; Murakami A; Nakamura S; Nakata H; Moriwaki K; Obata Y; Yoshiki A. 2009. Genetic differences among C57BL/6
substrains. Exp Anim 58(2):141-9. [PubMed: 19448337] [MGI Ref ID J:160204]
Miller MW; Duhl DM; Vrieling H; Cordes SP; Ollmann MM; Winkes BM; Barsh GS. 1993. Cloning of the mouse agouti gene predicts
a secreted protein ubiquitously expressed in mice carrying the lethal yellow mutation. Genes Dev 7(3):454-67. [PubMed:
8449404] [MGI Ref ID J:4186]
Moy SS; Nadler JJ; Young NB; Perez A; Holloway LP; Barbaro RP; Barbaro JR; Wilson LM; Threadgill DW; Lauder JM; Magnuson TR;
Crawley JN. 2007. Mouse behavioral tasks relevant to autism: phenotypes of 10 inbred strains. Behav Brain Res 176(1):4-20.
[PubMed: 16971002] [MGI Ref ID J:138682]
Nguyen PV; Duffy SN; Young JZ. 2000. Differential maintenance and frequency-dependent tuning of LTP at hippocampal synapses
of specific strains of inbred mice. J Neurophysiol 84(5):2484-93. [PubMed: 11067991] [MGI Ref ID J:71278]
Nishina PM; Wang J; Toyofuku W; Kuypers FA; Ishida BY; Paigen B. 1993. Atherosclerosis and plasma and liver lipids in nine inbred
strains of mice. Lipids 28(7):599-605. [PubMed: 8355588] [MGI Ref ID J:13267]
O'Malley J; Matesic LE; Zink MC; Strandberg JD; Mooney ML; De Maio A; Reeves RH. 1998. Comparison of acute endotoxin-induced
lesions in A/J and C57BL/6J mice. J Hered 89(6):525-30. [PubMed: 9864862] [MGI Ref ID J:51631]
Parekh PI; Petro AE; Tiller JM; Feinglos MN; Surwit RS. 1998. Reversal of diet-induced obesity and diabetes in C57BL/6J mice.
Metabolism 47(9):1089-96. [PubMed: 9751238] [MGI Ref ID J:49858]
Parham K. 1997. Distortion product otoacoustic emissions in the C57BL/6J mouse model of age-related hearing loss. Hear Res
112(1-2):216-34. [PubMed: 9367243] [MGI Ref ID J:44149]
Petkov PM; Ding Y; Cassell MA; Zhang W; Wagner G; Sargent EE; Asquith S; Crew V; Johnson KA; Robinson P; Scott VE; Wiles MV.
2004. An efficient SNP system for mouse genome scanning and elucidating strain relationships. Genome Res 14(9):1806-11.
[PubMed: 15342563] [MGI Ref ID J:151913]
Roberts JE; Watters JW; Ballard JD; Dietrich WF. 1998. Ltx1, a mouse locus that influences the susceptibility of macrophages to
cytolysis caused by intoxication with Bacillus anthracis lethal factor, maps to chromosome 11. Mol Microbiol 29(2):581-91.
[PubMed: 9720874] [MGI Ref ID J:49726]
Rohan RM; Fernandez A; Udagawa T; Yuan J; D'Amato RJ. 2000. Genetic heterogeneity of angiogenesis in mice. FASEB J
14(7):871-6. [PubMed: 10783140] [MGI Ref ID J:61808]
Rossmeisl M; Rim JS; Koza RA; Kozak LP. 2003. Variation in type 2 diabetes--related traits in mouse strains susceptible to
diet-induced obesity. Diabetes 52(8):1958-66. [PubMed: 12882911] [MGI Ref ID J:86027]
Sarna JR; Dyck RH; Whishaw IQ. 2000. The Dalila effect: C57BL6 mice barber whiskers by plucking. Behav Brain Res 108(1):39-45.
[PubMed: 10680755] [MGI Ref ID J:71538]
Schlagel CJ; Ahmed A. 1982. Evidence for genetic control of microwave-induced augmentation of complement receptor-bearing B
lymphocytes. J Immunol 129(4):1530-3. [PubMed: 6980940] [MGI Ref ID J:6835]
Smith BK; Andrews PK; West DB. 2000. Macronutrient diet selection in thirteen mouse strains. Am J Physiol Regul Integr Comp
Physiol 278(4):R797-805. [PubMed: 10749765] [MGI Ref ID J:61602]
Smith RS; Roderick TH; Sundberg JP. 1994. Microphthalmia and associated abnormalities in inbred black mice. Lab Anim Sci
44(6):551-60. [PubMed: 7898027] [MGI Ref ID J:24131]
Vrieling H; Duhl DM; Millar SE; Miller KA; Barsh GS. 1994. Differences in dorsal and ventral pigmentation result from regional
expression of the mouse agouti gene. Proc Natl Acad Sci U S A 91(12):5667-71. [PubMed: 8202545] [MGI Ref ID J:18750]
Welkos SL; Keener TJ; Gibbs PH. 1986. Differences in susceptibility of inbred mice to Bacillus anthracis. Infect Immun
51(3):795-800. [PubMed: 3081444] [MGI Ref ID J:8197]
West DB; Boozer CN; Moody DL; Atkinson RL. 1992. Dietary obesity in nine inbred mouse strains. Am J Physiol 262(6 Pt
2):R1025-32. [PubMed: 1621856] [MGI Ref ID J:1348]
Whitehead GS; Walker JK; Berman KG; Foster WM; Schwartz DA. 2003. Allergen-induced airway disease is mouse strain dependent.
Am J Physiol Lung Cell Mol Physiol 285(1):L32-42. [PubMed: 12626335] [MGI Ref ID J:84265]
Zhu W; Gilmour MI. 2009. Comparison of allergic lung disease in three mouse strains after systemic or mucosal sensitization with
ovalbumin antigen. Immunogenetics 61(3):199-207. [PubMed: 19224206] [MGI Ref ID J:146790]
Zurita E; Chagoyen M; Cantero M; Alonso R; Gonzalez-Neira A; Lopez-Jimenez A; Lopez-Moreno JA; Landel CP; Benitez J; Pazos F;
Montoliu L. 2010. Genetic polymorphisms among C57BL/6 mouse inbred strains. Transgenic Res :. [PubMed: 20506040] [MGI Ref
ID J:160203]
Ahrb-1 related
Benedict WF; Considine N; Nebert DW. 1973. Genetic differences in aryl hydrocarbon hydroxylase induction and
benzo(a)pyrene-produced tumorigenesis in the mouse. Mol Pharmacol 9(2):266-77. [PubMed: 4123113] [MGI Ref ID J:84312]
Boobis AR; Nebert DW. 1976. Genetic differences in the metabolism of carcinogens and in the binding of benzo (a) pyrene
metabolites to DNA. Adv Enzyme Regul 15:339-62. [PubMed: 1030186] [MGI Ref ID J:12156]
Bradfield CA; Glover E; Poland A. 1991. Purification and N-terminal amino acid sequence of the Ah receptor from the C57BL/6J
mouse. Mol Pharmacol 39(1):13-9. [PubMed: 1846217] [MGI Ref ID J:84440]
Burbach KM; Poland A; Bradfield CA. 1992. Cloning of the Ah-receptor cDNA reveals a distinctive ligand-activated transcription
factor. Proc Natl Acad Sci U S A 89(17):8185-9. [PubMed: 1325649] [MGI Ref ID J:2256]
Castro DJ; Lohr CV; Fischer KA; Pereira CB; Williams DE. 2008. Lymphoma and lung cancer in offspring born to pregnant mice dosed
with dibenzo[a,l]pyrene: the importance of in utero vs. lactational exposure. Toxicol Appl Pharmacol 233(3):454-8. [PubMed:
18848954] [MGI Ref ID J:143604]
Chang C; Smith DR; Prasad VS; Sidman CL; Nebert DW; Puga A. 1993. Ten nucleotide differences, five of which cause amino acid
changes, are associated with the Ah receptor locus polymorphism of C57BL/6 and DBA/2 mice. Pharmacogenetics 3(6):312-21.
[PubMed: 8148872] [MGI Ref ID J:17460]
Curran CP; Miller KA; Dalton TP; Vorhees CV; Miller ML; Shertzer HG; Nebert DW. 2006. Genetic differences in lethality of newborn
mice treated in utero with coplanar versus non-coplanar hexabromobiphenyl. Toxicol Sci 89(2):454-64. [PubMed: 16291824] [MGI
Ref ID J:113285]
Ema M; Sogawa K; Watanabe N; Chujoh Y; Matsushita N; Gotoh O; Funae Y; Fujii-Kuriyama Y. 1992. cDNA cloning and structure of
mouse putative Ah receptor. Biochem Biophys Res Commun 184(1):246-53. [PubMed: 1314586] [MGI Ref ID J:477]
Gielen JE; Goujon FM; Nebert DW. 1972. Genetic regulation of aryl hydrocarbon hydroxylase induction. II. Simple Mendelian
expression in mouse tissues in vivo. J Biol Chem 247(4):1125-37. [PubMed: 4110756] [MGI Ref ID J:84250]
Goujon FM; Nebert DW; Gielen JE. 1972. Genetic expression of aryl hydrocarbon hydroxylase induction. IV. Interaction of various
compounds with different forms of cytochrome P-450 and the effect on benzo(a)pyrene metabolism in vitro. Mol Pharmacol
8(6):667-80. [PubMed: 4118365] [MGI Ref ID J:84252]
Harper PA; Golas CL; Okey AB. 1991. Ah receptor in mice genetically nonresponsive for cytochrome P4501A1 induction: cytosolic Ah
receptor, transformation to the nuclear binding state, and induction of aryl hydrocarbon hydroxylase by halogenated and
nonhalogenated aromatic hydrocarbons in embryonic tissues and cells. Mol Pharmacol 40(5):818-26. [PubMed: 1658612] [MGI
Ref ID J:2134]
Kerley-Hamilton JS; Trask HW; Ridley CJ; Dufour E; Lesseur C; Ringelberg CS; Moodie KL; Shipman SL; Korc M; Gui J; Shworak NW;
Tomlinson CR. 2012. Inherent and benzo[a]pyrene-induced differential aryl hydrocarbon receptor signaling greatly affects life span,
atherosclerosis, cardiac gene expression, and body and heart growth in mice. Toxicol Sci 126(2):391-404. [PubMed:
22228805] [MGI Ref ID J:183715]
Kouri RE; Rude TH; Joglekar R; Dansette PM; Jerina DM; Atlas SA; Owens IS; Nebert DW. 1978.
2,3,7,8-tetrachlorodibenzo-p-dioxin as cocarcinogen causing 3-methylcholanthrene-initiated subcutaneous tumors in mice
genetically 'nonresponsive' at Ah locus. Cancer Res 38(9):2777-83. [PubMed: 679184] [MGI Ref ID J:84318]
Lew BJ; Manickam R; Lawrence BP. 2011. Activation of the aryl hydrocarbon receptor during pregnancy in the mouse alters
mammary development through direct effects on stromal and epithelial tissues. Biol Reprod 84(6):1094-102. [PubMed:
21270426] [MGI Ref ID J:173706]
Moriguchi T; Motohashi H; Hosoya T; Nakajima O; Takahashi S; Ohsako S; Aoki Y; Nishimura N; Tohyama C; Fujii-Kuriyama Y;
Yamamoto M. 2003. Distinct response to dioxin in an arylhydrocarbon receptor (AHR)-humanized mouse. Proc Natl Acad Sci U S A
100(10):5652-7. [PubMed: 12730383] [MGI Ref ID J:132380]
Nebert DW; Atlas SA; Guenthner TM; Kouri RE. 1978. The Ah locus: genetic regulation of the enzymes which metabolize polycyclic
hydrocarbons and the risk of cancer. In: Polycyclic Hydrocarbons and Cancer: Chemistry, Molecular Biology and Environment.
Academic Press, New York. [MGI Ref ID J:30693]
Nebert DW; Considine N; Owens IS. 1973. Genetic expression of aryl hydrocarbon hydroxylase induction. VI. Control of other
aromatic hydrocarbon-inducible mono-oxygenase activities at or near the same genetic locus. Arch Biochem Biophys 157(1):148-59.
[PubMed: 4716952] [MGI Ref ID J:84313]
Nebert DW; Gelboin HV. 1969. The in vivo and in vitro induction of aryl hydrocarbon hydroxylase in mammalian cells of different
species, tissues, strains, and developmental and hormonal states. Arch Biochem Biophys 134(1):76-89. [PubMed: 4981257] [MGI
Ref ID J:84248]
Nebert DW; Gielen JE. 1972. Genetic regulation of aryl hydrocarbon hydroxylase induction in the mouse. Fed Proc 31(4):1315-25.
[PubMed: 4114109] [MGI Ref ID J:5282]
Nebert DW; Gielen JE; Goujon FM. 1972. Genetic expression of aryl hydrocarbon hydroxylase induction. 3. Changes in the binding
of n-octylamine to cytochrome P-450. Mol Pharmacol 8(6):651-66. [PubMed: 4118364] [MGI Ref ID J:84251]
Nebert DW; Goujon FM; Gielen JE. 1972. Aryl hydrocarbon hydroxylase induction by polycyclic hydrocarbons: simple autosomal
dominant trait in the mouse. Nat New Biol 236(65):107-10. [PubMed: 4502804] [MGI Ref ID J:84249]
Nebert DW; Robinson JR; Niwa A; Kumaki K; Poland AP. 1975. Genetic expression of aryl hydrocarbon hydroxylase activity in the
mouse. J Cell Physiol 85(2 Pt 2 Suppl 1):393-414. [PubMed: 1091656] [MGI Ref ID J:84317]
Niwa A; Kumaki K; Nebert DW; Poland AP. 1975. Genetic expression of aryl hydrocarbon hydroxylase activity in the mouse.
Distinction between the 'responsive' homozygote and heterozygote at the Ah locus. Arch Biochem Biophys 166(2):559-64.
[PubMed: 1119809] [MGI Ref ID J:84316]
Nukaya M; Lin BC; Glover E; Moran SM; Kennedy GD; Bradfield CA. 2010. The aryl hydrocarbon receptor-interacting protein (AIP)
is required for dioxin-induced hepatotoxicity but not for the induction of the Cyp1a1 and Cyp1a2 genes. J Biol Chem
285(46):35599-605. [PubMed: 20829355] [MGI Ref ID J:166864]
Okey AB; Vella LM; Harper PA. 1989. Detection and characterization of a low affinity form of cytosolic Ah receptor in livers of mice
nonresponsive to induction of cytochrome P1-450 by 3-methylcholanthrene. Mol Pharmacol 35(6):823-30. [PubMed:
2543914] [MGI Ref ID J:27899]
Poel WE; Stanton D; Peters E; Wade HO. 1958. Comparative susceptibilities of seven inbred strains of mice to qualified applications
of 3, 4-benzpyrene Proc Am Assoc Cancer Res 2:335. [MGI Ref ID J:84245]
Poland A; Bradfield C. 1992. A brief review of the Ah locus. Tohoku J Exp Med 168(2):83-7. [PubMed: 1339107] [MGI Ref ID
J:12546]
Poland A; Glover E. 1990. Characterization and strain distribution pattern of the murine Ah receptor specified by the Ahd and Ahb-3
alleles. Mol Pharmacol 38(3):306-12. [PubMed: 2169579] [MGI Ref ID J:34840]
Poland A; Glover E; Kende AS. 1976. Stereospecific, high affinity binding of 2,3,7,8-tetrachlorodibenzo-p-dioxin by hepatic cytosol.
Evidence that the binding species is receptor for induction of aryl hydrocarbon hydroxylase. J Biol Chem 251(16):4936-46.
[PubMed: 956169] [MGI Ref ID J:84247]
Poland A; Glover E; Taylor BA. 1987. The murine Ah locus: a new allele and mapping to chromosome 12. Mol Pharmacol 32(4):471-8.
[PubMed: 2823093] [MGI Ref ID J:8895]
Poland A; Palen D; Glover E. 1994. Analysis of the four alleles of the murine aryl hydrocarbon receptor. Mol Pharmacol 46(5):915-21.
[PubMed: 7969080] [MGI Ref ID J:22144]
Poland AP; Glover E; Robinson JR; Nebert DW. 1974. Genetic expression of aryl hydrocarbon hydroxylase activity. Induction of
monooxygenase activities and cytochrome P1-450 formation by 2,3,7,8-tetrachlorodibenzo-p-dioxin in mice genetically
'nonresponsive' to other aromatic hydrocarbons. J Biol Chem 249(17):5599-606. [PubMed: 4370044] [MGI Ref ID J:84314]
Robinson JR; Considine N; Nebert DW. 1974. Genetic expression of aryl hydrocarbon hydroxylase induction. Evidence for the
involvement of other genetic loci. J Biol Chem 249(18):5851-9. [PubMed: 4413562] [MGI Ref ID J:84315]
Schmid FA; Demetriades MS; Schabel FM 3rd; Tarnowski GS. 1967. Toxicity of several cancerigenic polycyclic hydrocarbons and
other agents in AKR and C57BL-6 mice. Cancer Res 27(3):563-7. [PubMed: 6021514] [MGI Ref ID J:84246]
Schmid FA; Elmer I; Tarnowski GS. 1969. Genetic determination of differential inflammatory reactivity and subcutaneous tumor
susceptibility of AKR-J and C57BL-6J mice to 7,12-dimethylbenz- [a]anthracene. Cancer Res 29(8):1585-9. [PubMed:
5807232] [MGI Ref ID J:34134]
Schmid FA; Pena RC; Robinson W; Tarnowski GS. 1967. Toxicity of intraperitoneal injections of 7, 12-dimethylbenz[a]anthracene in
inbred mice. Cancer Res 27(3):558-62. [PubMed: 6021513] [MGI Ref ID J:26440]
Schmidt JV; Carver LA; Bradfield CA. 1993. Molecular characterization of the murine Ahr gene. Organization, promoter analysis, and
chromosomal assignment. J Biol Chem 268(29):22203-9. [PubMed: 8408082] [MGI Ref ID J:15153]
Smith AG; Clothier B; Robinson S; Scullion MJ; Carthew P; Edwards R; Luo J; Lim CK; Toledano M. 1998. Interaction between iron
metabolism and 2,3,7,8-tetrachlorodibenzo-p-dioxin in mice with variants of the Ahr gene: a hepatic oxidative mechanism. Mol
Pharmacol 53(1):52-61. [PubMed: 9443932] [MGI Ref ID J:45850]
Stiborova M; Levova K; Barta F; Shi Z; Frei E; Schmeiser HH; Nebert DW; Phillips DH; Arlt VM. 2012. Bioactivation versus
detoxication of the urothelial carcinogen aristolochic acid I by human cytochrome P450 1A1 and 1A2. Toxicol Sci 125(2):345-58.
[PubMed: 22086975] [MGI Ref ID J:183662]
Taylor BA. 1971. Strain distribution and linkage tests of 7,12-dimethylbenzanthracene (DMBA) inflammatory response in mice. Life
Sci I 10(19):1127-34. [PubMed: 5132702] [MGI Ref ID J:5244]
Thomas PE; Hutton JJ; Taylor BA. 1973. Genetic relationship between aryl hydrocarbon hydroxylase inducibility and chemical
carcinogen induced skin ulceration in mice. Genetics 74(4):655-9. [PubMed: 4750810] [MGI Ref ID J:5387]
Thomas PE; Kouri RE; Hutton JJ. 1972. The genetics of aryl hydrocarbon hydroxylase induction in mice: a single gene difference
between C57BL-6J and DBA-2J. Biochem Genet 6(2):157-68. [PubMed: 4666754] [MGI Ref ID J:31977]
Yu Z; Mahadevan B; Lohr CV; Fischer KA; Louderback MA; Krueger SK; Pereira CB; Albershardt DJ; Baird WM; Bailey GS; Williams
DE. 2006. Indole-3-carbinol in the maternal diet provides chemoprotection for the fetus against transplacental carcinogenesis by the
polycyclic aromatic hydrocarbon dibenzo[a,l]pyrene. Carcinogenesis 27(10):2116-23. [PubMed: 16704990] [MGI Ref ID
J:113356]
Cdh23ahl related
Davis RR; Newlander JK; Ling X; Cortopassi GA; Krieg EF; Erway LC. 2001. Genetic basis for susceptibility to noise-induced hearing
loss in mice. Hear Res 155(1-2):82-90. [PubMed: 11335078] [MGI Ref ID J:69679]
Di Palma F; Pellegrino R; Noben-Trauth K. 2001. Genomic structure, alternative splice forms and normal and mutant alleles of
cadherin 23 (Cdh23). Gene 281(1-2):31-41. [PubMed: 11750125] [MGI Ref ID J:73941]
Fetoni AR; Picciotti PM; Paludetti G; Troiani D. 2011. Pathogenesis of presbycusis in animal models: a review. Exp Gerontol
46(6):413-25. [PubMed: 21211561] [MGI Ref ID J:186964]
Han F; Yu H; Tian C; Chen HE; Benedict-Alderfer C; Zheng Y; Wang Q; Han X; Zheng QY. 2010. A new mouse mutant of the Cdh23
gene with early-onset hearing loss facilitates evaluation of otoprotection drugs. Pharmacogenomics J :. [PubMed: 20644563] [MGI
Ref ID J:174758]
Johnson KR; Erway LC; Cook SA; Willott JF; Zheng QY. 1997. A major gene affecting age-related hearing loss in C57BL/6J mice Hear
Res 114(1-2):83-92. [PubMed: 9447922] [MGI Ref ID J:44966]
Johnson KR; Longo-Guess C; Gagnon LH; Yu H; Zheng QY. 2008. A locus on distal chromosome 11 (ahl8) and its interaction with
Cdh23 ahl underlie the early onset, age-related hearing loss of DBA/2J mice. Genomics 92(4):219-25. [PubMed: 18662770] [MGI
Ref ID J:139223]
Johnson KR; Yu H; Ding D; Jiang H; Gagnon LH; Salvi RJ. 2010. Separate and combined effects of Sod1 and Cdh23 mutations on
age-related hearing loss and cochlear pathology in C57BL/6J mice. Hear Res 268(1-2):85-92. [PubMed: 20470874] [MGI Ref ID
J:163035]
Johnson KR; Zheng QY; Bykhovskaya Y; Spirina O; Fischel-Ghodsian N. 2001. A nuclear-mitochondrial DNA interaction affecting
hearing impairment in mice. Nat Genet 27(2):191-4. [PubMed: 11175788] [MGI Ref ID J:67312]
Johnson KR; Zheng QY; Noben-Trauth K. 2006. Strain background effects and genetic modifiers of hearing in mice. Brain Res
1091(1):79-88. [PubMed: 16579977] [MGI Ref ID J:110459]
Johnson KR; Zheng QY; Weston MD; Ptacek LJ; Noben-Trauth K. 2005. The Mass1(frings) mutation underlies early onset hearing
impairment in BUB/BnJ mice, a model for the auditory pathology of Usher syndrome IIC. Genomics 85(5):582-90. [PubMed:
15820310] [MGI Ref ID J:97534]
Kane KL; Longo-Guess CM; Gagnon LH; Ding D; Salvi RJ; Johnson KR. 2012. Genetic background effects on age-related hearing loss
associated with Cdh23 variants in mice. Hear Res 283(1-2):80-8. [PubMed: 22138310] [MGI Ref ID J:183757]
Keithley EM; Canto C; Zheng QY; Fischel-Ghodsian N; Johnson KR. 2004. Age-related hearing loss and the ahl locus in mice. Hear
Res 188(1-2):21-8. [PubMed: 14759567] [MGI Ref ID J:87783]
Liu X; Bulgakov OV; Darrow KN; Pawlyk B; Adamian M; Liberman MC; Li T. 2007. Usherin is required for maintenance of retinal
photoreceptors and normal development of cochlear hair cells. Proc Natl Acad Sci U S A 104(11):4413-8. [PubMed:
17360538] [MGI Ref ID J:118927]
Manji SS; Williams LH; Miller KA; Ooms LM; Bahlo M; Mitchell CA; Dahl HH. 2011. A mutation in synaptojanin 2 causes progressive
hearing loss in the ENU-mutagenised mouse strain Mozart. PLoS One 6(3):e17607. [PubMed: 21423608] [MGI Ref ID J:171701]
Mathews CE; Leiter EH. 1999. Resistance of ALR/Lt islets to free radical-mediated diabetogenic stress is inherited as a dominant trait.
Diabetes 48(11):2189-96. [PubMed: 10535453] [MGI Ref ID J:109893]
Nadeau JH. 2003. Modifier genes and protective alleles in humans and mice. Curr Opin Genet Dev 13(3):290-5. [PubMed:
12787792] [MGI Ref ID J:88012]
Noben-Trauth K; Latoche JR; Neely HR; Bennett B. 2010. Phenotype and genetics of progressive sensorineural hearing loss (Snhl1)
in the LXS set of recombinant inbred strains of mice. PLoS One 5(7):e11459. [PubMed: 20628639] [MGI Ref ID J:163117]
Noben-Trauth K; Zheng QY; Johnson KR. 2003. Association of cadherin 23 with polygenic inheritance and genetic modification of
sensorineural hearing loss. Nat Genet 35(1):21-3. [PubMed: 12910270] [MGI Ref ID J:86905]
Noben-Trauth K; Zheng QY; Johnson KR; Nishina PM. 1997. mdfw: a deafness susceptibility locus that interacts with deaf waddler
(dfw). Genomics 44(3):266-72. [PubMed: 9325047] [MGI Ref ID J:38429]
Perrin BJ; Sonnemann KJ; Ervasti JM. 2010. beta-actin and gamma-actin are each dispensable for auditory hair cell development but
required for Stereocilia maintenance. PLoS Genet 6(10):e1001158. [PubMed: 20976199] [MGI Ref ID J:167543]
Vazquez AE; Jimenez AM; Martin GK; Luebke AE; Lonsbury-Martin BL. 2004. Evaluating cochlear function and the effects of noise
exposure in the B6.CAST+Ahl mouse with distortion product otoacoustic emissions. Hear Res 194(1-2):87-96. [PubMed:
15276680] [MGI Ref ID J:117746]
Zheng QY; Johnson KR. 2001. Hearing loss associated with the modifier of deaf waddler (mdfw) locus corresponds with age-related
hearing loss in 12 inbred strains of mice. Hear Res 154(1-2):45-53. [PubMed: 11423214] [MGI Ref ID J:70964]
Zheng QY; Scarborough JD; Zheng Y; Yu H; Choi D; Gillespie PG. 2012. Digenic inheritance of deafness caused by 8J allele of
myosin-VIIA and mutations in other Usher I genes. Hum Mol Genet 21(11):2588-98. [PubMed: 22381527] [MGI Ref ID J:183898]
Zilberstein Y; Liberman MC; Corfas G. 2012. Inner hair cells are not required for survival of spiral ganglion neurons in the adult
cochlea. J Neurosci 32(2):405-10. [PubMed: 22238076] [MGI Ref ID J:179911]
Fbrwt1C57BL/6J related
Lu L; Wei L; Peirce JL; Wang X; Zhou J; Homayouni R; Williams RW; Airey DC. 2008. Using gene expression databases for classical
trait QTL candidate gene discovery in the BXD recombinant inbred genetic reference population: mouse forebrain weight. BMC
Genomics 9:444. [PubMed: 18817551] [MGI Ref ID J:143361]
Fbrwt2C57BL/6J related
Lu L; Wei L; Peirce JL; Wang X; Zhou J; Homayouni R; Williams RW; Airey DC. 2008. Using gene expression databases for classical
trait QTL candidate gene discovery in the BXD recombinant inbred genetic reference population: mouse forebrain weight. BMC
Genomics 9:444. [PubMed: 18817551] [MGI Ref ID J:143361]
Gluchos1C57BL/6J related
Freeman HC; Hugill A; Dear NT; Ashcroft FM; Cox RD. 2006. Deletion of Nicotinamide Nucleotide Transhydrogenase: A New
Quantitive Trait Locus Accounting for Glucose Intolerance in C57BL/6J Mice. Diabetes 55(7):2153-6. [PubMed: 16804088] [MGI
Ref ID J:109356]
Micrln related
Schlagel CJ; Ahmed A. 1982. Evidence for genetic control of microwave-induced augmentation of complement receptor-bearing B
lymphocytes. J Immunol 129(4):1530-3. [PubMed: 6980940] [MGI Ref ID J:6835]
NntC57BL/6J related
Freeman HC; Hugill A; Dear NT; Ashcroft FM; Cox RD. 2006. Deletion of Nicotinamide Nucleotide Transhydrogenase: A New
Quantitive Trait Locus Accounting for Glucose Intolerance in C57BL/6J Mice. Diabetes 55(7):2153-6. [PubMed: 16804088] [MGI
Ref ID J:109356]
Huang TT; Naeemuddin M; Elchuri S; Yamaguchi M; Kozy HM; Carlson EJ; Epstein CJ. 2006. Genetic modifiers of the phenotype of
mice deficient in mitochondrial superoxide dismutase. Hum Mol Genet 15(7):1187-94. [PubMed: 16497723] [MGI Ref ID
J:108213]
Kim A; Chen CH; Ursell P; Huang TT. 2010. Genetic modifier of mitochondrial superoxide dismutase-deficient mice delays heart
failure and prolongs survival. Mamm Genome 21(11-12):534-42. [PubMed: 21069343] [MGI Ref ID J:166767]
Meimaridou E; Kowalczyk J; Guasti L; Hughes CR; Wagner F; Frommolt P; Nurnberg P; Mann NP; Banerjee R; Saka HN; Chapple JP;
King PJ; Clark AJ; Metherell LA. 2012. Mutations in NNT encoding nicotinamide nucleotide transhydrogenase cause familial
glucocorticoid deficiency. Nat Genet 44(7):740-2. [PubMed: 22634753] [MGI Ref ID J:185986]
Navarro SJ; Trinh T; Lucas CA; Ross AJ; Waymire KG; Macgregor GR. 2012. The C57BL/6J Mouse Strain Background Modifies the
Effect of a Mutation in Bcl2l2. G3 (Bethesda) 2(1):99-102. [PubMed: 22384386] [MGI Ref ID J:186862]
Parker N; Vidal-Puig AJ; Azzu V; Brand MD. 2009. Dysregulation of glucose homeostasis in nicotinamide nucleotide
transhydrogenase knockout mice is independent of uncoupling protein 2. Biochim Biophys Acta 1787(12):1451-7. [PubMed:
19539600] [MGI Ref ID J:153452]
Wong N; Blair AR; Morahan G; Andrikopoulos S. 2010. The deletion variant of nicotinamide nucleotide transhydrogenase (Nnt) does
not affect insulin secretion or glucose tolerance. Endocrinology 151(1):96-102. [PubMed: 19906813] [MGI Ref ID J:168281]
P2rx7P451L related
Adriouch S; Dox C; Welge V; Seman M; Koch-Nolte F; Haag F. 2002. Cutting Edge: A Natural P451L Mutation in the Cytoplasmic
Domain Impairs the Function of the Mouse P2X7 Receptor. J Immunol 169(8):4108-12. [PubMed: 12370338] [MGI Ref ID J:79540]
Le Stunff H; Auger R; Kanellopoulos J; Raymond MN. 2004. The Pro-451 to Leu polymorphism within the C-terminal tail of P2X7
receptor impairs cell death but not phospholipase D activation in murine thymocytes. J Biol Chem 279(17):16918-26. [PubMed:
14761980] [MGI Ref ID J:89513]
Sorge RE; Trang T; Dorfman R; Smith SB; Beggs S; Ritchie J; Austin JS; Zaykin DV; Meulen HV; Costigan M; Herbert TA;
Yarkoni-Abitbul M; Tichauer D; Livneh J; Gershon E; Zheng M; Tan K; John SL; Slade GD; Jordan J; Woolf CJ; Peltz G; Maixner W;
DiatchenkoL; Seltzer Z; Salter MW; Mogil JS. 2012. Genetically determined P2X7 receptor pore formation regulates variability in
chronic pain sensitivity. Nat Med 18(4):595-9. [PubMed: 22447075] [MGI Ref ID J:183554]