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N-cadherin in osteolineage cells is not required for
maintenance of hematopoietic stem cells
by Adam M. Greenbaum, Leila D. Revollo, Jill R. Woloszynek, Roberto Civitelli, and
Daniel C. Link
Blood
Volume 120(2):295-302
July 12, 2012
©2012 by American Society of Hematology
N-cadherin expression is efficiently ablated in osteoblast lineage cells in Osx-Cre Cdh2flox/flox
mice.
Adam M. Greenbaum et al. Blood 2012;120:295-302
©2012 by American Society of Hematology
Basal hematopoiesis is normal in N-cadherin–deleted mice.
Adam M. Greenbaum et al. Blood 2012;120:295-302
©2012 by American Society of Hematology
HSC number and long-term repopulating activity are normal in N-cadherin–deleted mice.
Adam M. Greenbaum et al. Blood 2012;120:295-302
©2012 by American Society of Hematology
HSC cell cycling is normal in N-cadherin–deleted mice.
Adam M. Greenbaum et al. Blood 2012;120:295-302
©2012 by American Society of Hematology
G-CSF induced hematopoietic progenitor mobilization is normal in N-cadherin–deleted mice.
Adam M. Greenbaum et al. Blood 2012;120:295-302
©2012 by American Society of Hematology
Response to 5-FU is normal in N-cadherin–deleted mice.
Adam M. Greenbaum et al. Blood 2012;120:295-302
©2012 by American Society of Hematology
N-cadherin–deleted mice are osteopenic.
Adam M. Greenbaum et al. Blood 2012;120:295-302
©2012 by American Society of Hematology
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