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39
Beginning of the chapter
Heart health and genetics
(Cardiovascular Sensor)
SENSORS
CARDIOVASCULAR SENSOR
Cholesterol/Triglycerides
Homocysteine
Arteriosclerosis
Sudden cardiac arrest
SENSORS
CARDIOVASCULAR SENSOR
Predisposition to:
1) High LDL cholesterol
2) Low HDL cholesterol
1) Effect of omega-3 on HDL cholesterol
3) High triglycerides
4) High homocysteine
1) Vitamin B2 positively effects the
homocysteine levels
5) Prolongation of the QT intervals
6) Effect of 26 drugs
CARDIOVASCULAR DISEASES
22 genetic variations
CARDIOVASCULAR DISEASES
Gene examples
CARDIOVASCULAR DISEASES
Gene examples
CARDIOVASCULAR DISEASES
Gene examples
CARDIOVASCULAR DISEASES
Gene examples
CARDIOVASCULAR DISEASES
Gene examples
CARDIOVASCULAR DISEASES
Gene examples
CARDIOVASCULAR DISEASES
Gene examples
CARDIOVASCULAR DISEASES
Genetic predisposition
SENSORS
CARDIOVASCULAR SENSOR
Cardiovascular disease
1) Prevention
2) Early detection
3) Better treatment
CARDIOVASCULAR DISEASES
Counselling example
Prevention
Regular exercises
Do not smoke!
As little alcohol as possible
Low-fat diet
Less animal, more plant foods
Use vegetable oils
Omega3 fish oil capsules have a negative impact on your cholesterol
Early detection
Regular medical blood tests
Submit to a Resting ECG examination before taking QT altering
medication
CARDIOVASCULAR DISEASES
High risk, what to do now?
Early detection
Regular medical blood tests
Regular QT interval tests
Measure the electrolyte level when performing extreme sports
SENSORS
CARDIOVASCULAR SENSOR
Cardiovascular disease
1) Prevention
2) Early detection
3) Better treatment
PHARMACOGENETICS
Various drugs and enzymes
DRUG A
DRUG B
DRUG D
DRUG C
NAT2
2E9
1A2
2C19
2C9
2D6
break down
3A4
3A5
CARDIOVASCULAR DISEASES
Optimal medication
CARDIOVASCULAR DISEASES
Optimal medication
SENSORS
CARDIOVASCULAR SENSOR
Cardiovascular disease
1) Prevention
2) Early detection
3) Better treatment
39
End of the chapter
Heart health and genetics
(Cardiovascular Sensor)
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