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Phase 3 trial of defibrotide for the treatment of severe
veno-occlusive disease and multi-organ failure
by Paul G. Richardson, Marcie L. Riches, Nancy A. Kernan, Joel A. Brochstein, Shin
Mineishi, Amanda M. Termuhlen, Sally Arai, Stephan A. Grupp, Eva C. Guinan, Paul
L. Martin, Gideon Steinbach, Amrita Krishnan, Eneida R. Nemecek, Sergio Giralt,
Tulio Rodriguez, Reggie Duerst, John Doyle, Joseph H. Antin, Angela Smith, Leslie
Lehmann, Richard Champlin, Alfred Gillio, Rajinder Bajwa, Ralph B. D’Agostino,
Joseph Massaro, Diane Warren, Maja Miloslavsky, Robin L. Hume, Massimo
Iacobelli, Bijan Nejadnik, Alison L. Hannah, and Robert J. Soiffer
Blood
Volume 127(13):1656-1665
March 31, 2016
©2016 by American Society of Hematology
Participant flow in the defibrotide group.
Paul G. Richardson et al. Blood 2016;127:1656-1665
©2016 by American Society of Hematology
Participant flow in the historical-control group.
Paul G. Richardson et al. Blood 2016;127:1656-1665
©2016 by American Society of Hematology
Kaplan–Meier estimate.
Paul G. Richardson et al. Blood 2016;127:1656-1665
©2016 by American Society of Hematology
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