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What is Mitosis? • Mitosis: Cell division involving somatic (nonsex) cells • Involves only diploid cells • Form of asexual reproduction for some life (bacteria & protista, fungi) • End Result: Two genetically identical “daughter cells” The Cell Cycle • Defined: Repeating set of events in the life of a cell • 1) Interphase – G1, S, G2 2) Prophase 3) Metaphase 4) Anaphase 5) Telophase mitosis • • • • Interphase • Divided into 3 Stages: • G1 Stage – Normal function performed – Cell growth – Organelles created • S Stage – Chromatin (DNA strands) duplicated • G2 Stage – Cell growth – Normal function performed Mitosis A Quick Overview Prophase • 1st Mitosis Stage • Chromatin (DNA strands) coils into chromosomes • Nuclear envelope dissolves (nucleus) • Spindle fibers form between centrioles Metaphase • 2nd stage of mitosis • Spindle fibers attach to centromere of chromosome • Spindle fibers pull chromosomes to cell equator Anaphase • 3rd stage of mitosis • Sister chromatids separate • Spindle fibers pull sister chromatids to opposite ends – Humans: 46 chromatids each way Telophase • 4th stage of mitosis • Spindle fibers dissolve • Chromatids unwind into chromatin • Nucleus reforms • Cytokinesis: division of the cytoplasm Mitosis: An Animated Video Mitosis in a Real Cell Name that Stage! Hint: Chromosomes are aligned in middle of cell Name that Stage! Hint: Cell plate is splitting the cell Name that Stage! Hint: Two normal looking nuclei of two cells Name that Stage! Hint: Chromosomes are forming and the nucleus is gone Name that Stage! Hint: Chromatids are being pulled apart Kobe Kuiz 1) In order, name the 5 stages of the cell cycle. 2) Pick a stage of the cell cycle. Name two things that happen in this stage. 3) Review the picture slides. Identify the stages based on the picture. 4) The division of the cytoplasm is called _____. 5) Which cells divide by mitosis? 6) During which interphase stage is DNA created? 7) During which stage do spindle fibers form? 8) During which stage are chromosomes aligned in the middle? 9) During which stage are chromatids separated? 10) During which stage does the nucleus dissolve? Name this stage of the cell cycle. Name this stage of the cell cycle. Name this stage of the cell cycle. Name this stage of the cell cycle. Name this stage of the cell cycle. Name this stage of the cell cycle. Name this stage of the cell cycle. Name this stage of the cell cycle. Name this stage of the cell cycle. Name this stage of the cell cycle. Name this stage of the cell cycle. Name this stage of the cell cycle. Name this stage of the cell cycle.