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Relationship between Chromosomes (right) and a Gene. Each human chromosome (far left, whose DNA content is graphically illustrated as far left bar)
contains approximately 1000–2000 genes arranged in clusters of approximately 20 genes. Within the gene are “expressed sequences” (exons, dark
orange) and “intervening sequences” (introns, light orange). The intervening sequences are removed during expression of the primary mRNA transcript
and processing to the final mRNA product. Introns do not appear to code for any protein and their role, if any, is still unknown. Length of molecules is
indicated as bp (base pairs) or nt (nucleotides). [(Left part) Reproduced with permission from Mescher AL: Junqueira's Basic Histology Text and Atlas,
12th edition, McGraw-Hill, 2010. (Right part) Adapted with permission from Murray RA, et al.: Harper's Illustrated Biochemistry, 28th edition, McGraw-Hill,
Source: Chapter 4. Nucleosides, Nucleotides, DNA, and RNA, The Big Picture: Medical Biochemistry
2009.]
Citation: Janson LW, Tischler ME. The Big Picture: Medical Biochemistry; 2012 Available at: http://mhmedical.com/ Accessed: June 11, 2017
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