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Family planning Xiaoying Yao MD, PhD Department of family planning Obstetrics & Gynecology Hospital, Fudan University •Contraception •Induced abortion How Pregnancy (Conception) Occurs Contraception mechanism • Prevents ovulation • Thickens mucus at the cervix so sperm cannot pass through • Changes the environment of the uterus and fallopian tubes to prevent fertilization and to prevent implantation if fertilization occurs • Block sperm from reaching the egg Contraception mechanism controception methods • female – IUD – Hormonal contraception – Emergency contraceptive – External contraception • femshield • spermicide – Safe period contraception – Contraceptive vaccines – sterilization • male – condom – sterilization So many…… Contraceptive methods Map of the use of various of contraception in China & developed countries 口服避孕药 1.69% Oral contraceptive Subcutaneous implantation 皮下埋置剂 0.36% IUD 宫内节育器 49.79% 杀精剂 避孕套 Spermicide 5.72% 0.26% Condom Others 其他 Male sterilization 0.17% 男性绝育 7.39% 女性绝育 34.62% Female sterilization 阴道屏障避孕 4.20% Vaginal barrier IUD 宫内节育器 14.60% 避孕套 23.70% Condom 注射/皮埋 1.30% Injection/subcutaneo us implantation 其他Others 0.10% 口服避孕药 28.40% Oral contraceptive 绝育 27.70% Sterilization United Nations Department of Economic and Social Affairs Population Division: World contraceptive Use 2003 IUD(intrauterine device ) • Types of IUD • Inertia IUD(first generation) • Active IUD(second generation) – Copper-containing IUD(include nonsupport IUD) – Medicine-containing IUD • LNG-IUD • Indomethacin-IUD IUD mechanism of action • Killing sperm & embryo poison • Interference implantation • LNG mechanism The active ingredient: Levonorgestrel Intrauterine Contraception Thickening of the cervical mucus It prevents thickening of the womb lining Prevent ovulation Mirena® Heavy Menstrual Bleeding insert •Time •Contraindication: •genital tract inflammation Follow-up 1,3,6,12 month after the IUD insertion, to make sure it is in place. Once a year. Useful life The copper IUD is approved for use for up to 10 years. The hormonal IUD is approved for use for up to 5 years. IUD side effect and complication • Side effect – – – – – Heavy bleeding Prolonged menstruation Spotting Discharge increasing Abdominal pain • Complication – – – – – – Ectopic prognancy Embedment Crack Down Fall off Pregnancy with IUD Takeout Contraception methods – IUD – Hormonal – Others • Emergency contraception • External use contraceptive Hormonal contraception • Contraceptive mechanism – Suppression of ovulation – Changes in the cervical mucus properties – Morphologic and functional changes of endometrial – Change the function of fallopian tube Hormonal contraception -Types • Oral contraceptives • long-acting reversible contraceptives (LARC) – Long-acting contraceptive injection (DMPA) – Sustained release contraceptives (Norplant、Implanol) You will be given a local anesthetic and asked to lie on back, with non-dominant arm slightly bent at the elbow and turned outwards. The skin is stretched and a needle containing the implant is inserted directly under, and parallel to, the skin on the inside of upper arm. The implant will then remain under the skin when the needle is withdrawn Available options for LARC Injection, effective up to 12 weeks Levonorgestrel (LNG) intrauterine system, effective for up to 5 years Copper intrauterine device (IUD), effective for up to 10 years Implants, effective for up to 3-7 years Hormonal contraception –Oral contraceptives – Ingredient: estrogen + progesterone – Short-acting – long-term – combination oral contraceptive – Three-phase pills – Four-phase pills Development trend of OC Gradually reduce the dose of estrogen 200 150 • Reduce the chances of coagulation system – • • 100 To reduce the incidence of thrombosis To reduce the subjective side effects 50 – nausea – Vomiting 0 – breast tenderness 1960 1970 1980 1990 Increased tolerance The lowest estrogen content of oral contraceptives Mercilon® Contraindications to hormone contraception • Cardiovascular disease, thrombosis • Acute / chronic hepatitis / nephritis • Malignant neoplasms, precancerous lesions • Endocrine disease • Smoking • Mental disease • Recurrent severe migraine Side effects of hormonal contraception • • • • • Early pregnancy reaction Menstrual disorders Body weight change Skin problems Headache, diplopia, breast swelling Non contraceptive benefits of hormonal contraception •Treatment of bleeding and control cycle •The treatment of endometriosis •Improvement of premenstrual syndrome •Reducing osteoporosis Contraception methods – IUD – Hormonal – Others • Emergency contraception • External use contraceptive What is emergency contraception? • Emergency contraception is a way to prevent pregnancy if: – Sex without using birth control – Birth control method failed • forgot to take pill or get shot • the condom broke or came off • diaphragm slipped – Be raped What are the types of emergency contraception? • Pills – work well – don't cost a lot – usually easy to get • Copper intrauterine device (IUD). – works very well – but it has to be inserted by a doctor How does it work? • Emergency contraception pills work by – preventing ovulation – preventing fertilization – preventing implantation – 96% effective • The copper IUD may work by – killing sperm – preventing fertilization – preventing implantation – 99% effective Does it cause side effects? • Emergency contraception may cause some side effects – spotting or mild symptoms like those of birth control pills – nausea or vomiting – sore breasts, fatigue, headache, belly pain, or dizziness – An IUD may cause cramping and bleeding during the first few days after insertion What else should you think about? • Emergency contraception pills won't protect you for the rest of your cycle. Use your regular method of birth control, or use condoms. • Unless you get an IUD, emergency contraception does not take the place of regular birth control. Find a good method of birth control you can use every time you have sex. • Emergency contraception does not prevent sexually transmitted infections (STIs). Method Barrier methods Fertility awareness (natural family planning) Permanent birth control (sterilization) How it prevents pregnancy •Block sperm from reaching the egg •Some are used with spermicides, which kill sperm. •Identifies the time during a woman's cycle when she is most likely to become pregnant (fertile). An additional method or abstinence should be used during this time of fertility. •Men: Vasectomy blocks the release of sperm. •Women: Tubal ligation surgery or tubal implants block the movement of an egg through the fallopian tube, preventing fertilization. Tubal sterilization operation • Ligation method – The proximal embedding method – Madlener 电绝育法 – Pomeroy – Falope ring – Hulka clip Madlener Pomeroy The choice of family planning methods •The wedding •Lactation •After birth •Menopausal transition period • Contraception • Induced abortion • Termination of early pregnancy---- Artificial abortion – Surgical abortion • Vacuum aspiration<10w – Medical abortion • <7w Common complications Uterine perforation and visceral injury Incomplete abortion Uterine hemorrhage Bleeding in operation Complication Induced Abortion syndrome Cervical and intrauterine adhesions Infection Miss-suction or leakage Regret syndrome (long-term) Medical abortion Overview and history Medical abortion Mechanism of action Mifepristone: blocks the action of progesterone causes the cervix to soften Misoprostol: causes the uterus to contract causes the cervix to soften Medical abortion • Is a kind of non operation of artificial abortion • Could reduce the fear and pain on the operation of women • Long bleeding time and the potential risk of major bleeding • Is the only remedy for contraception failure • Not a contraceptive method vaginal bleeding Vacuum abortion <7 days Medical abortion 14-15 days 19.2% complete abortion >21 days 1.5% 0.16% emergency curettage blood transfusion Medical contraindications • Mifepristone: – – – – endocrine disease history of ICP blood disease history of thrombosis • Prostaglandin contraindications: – – – – – cardiovascular disease Glaucoma Asthma Epilepsy colitis • Other: – allergic constitution – IUD with pregnancy – ectopic pregnancy – hyperemesis gravidarum – medication (anti tuberculosis, epilepsy, anti depression, anti prostaglandin drug) Questions?