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Single-stranded DNA, non-enveloped – Parvoviridae • Human parvovirus • Fifth disease • Anemia Double-stranded DNA, non-enveloped • Mastadenovirus – Respiratory infections – Tumors Double-stranded DNA, non-enveloped – named for papillomas (warts) and polyomas (tumors) • Papillomavirus – human papilloma virus – one of the leading STD’s in the U.S. Double-stranded DNA, enveloped – Cause diseases involving pus-filled skin lesions (pox) • Orthopoxvirus – smallpox (variola) virus • Molluscipoxvirus – molluscum contagiosum, cowpox Double-stranded DNA, enveloped – named for spreading (herpetic) sores – Some can remain latent – Simplexvirus (HHV-1 & 2) • cold sores and genital herpes – Varicellavirus (HHV-3) • chickenpox – Lympocryptovirus (HHV-4) • infectious mononucleosis – Roseolovirus (HHV-6) • roseola – (HHV-8) • Kaposi’s sarcoma, in AIDS patients Double-stranded DNA, enveloped • Hepadnavirus – Hepatitis B virus – Hepatitis and liver tumors – reverse transcriptase – oncovirus Single-stranded RNA, + strand, non-enveloped – Smallest viruses • Enterovirus – 70 known Enteroviruses including the poliovirus • Rhinovirus – More than 100 exist – Primary cause of common cold • Hepatitis A virus Single-stranded RNA, + strand, non-enveloped • Hepatitis E virus • Norovirus – causes gastroenteritis Single-stranded RNA, + strand, enveloped • Arbovirus – functional grouping – replicate in arthropods • Alphavirus – include EEE, WEE viruses • Rubivirus – rubella – Transmitted by respiratory route Single-stranded RNA, + strand, enveloped • Arbovirus • Flavivirus – West Nile virus – Hepatitis C virus – Yellow fever virus – Dengue fever virus Single-stranded RNA, + strand, enveloped • Coronavirus – Upper respiratory infections and the common cold – SARS virus Single-stranded RNA, – strand, enveloped – Bullet shaped with spikes • Lyssavirus – rabies virus – numerous other animal diseases Single-stranded RNA, – strand, one strand • Filovirus – Enveloped, helical viruses – Ebola and Marburg viruses Single-stranded RNA, – strand, one strand • Paramyxovirus – parainfluenza and mumps • Morbillivirus – Measles-like virus Single-stranded RNA, – strand, one strand • Hepatitis D virus – Depends on coinfection with Hepadnavirus (hepatitis B) Single-stranded RNA, – strand, multiple strands • Influenzavirus – Influenza viruses A, B and C • Envelope spikes can agglutinate RBCs Single-stranded RNA, – strand, multiple strands • Bunyavirus – California Encephalitis virus • Hantavirus – Pulmonary syndrome associated with rodents and hemorrhagic fevers Single-stranded RNA, – strand, multiple strands • Arenavirus – Helical capsids contain RNA-containing granules – Lassa Fever Single-stranded RNA, two + strands, produce DNA • Lentivirus – Human Immunodeficiency Virus – Reverse transcriptase • Oncovirus – Includes all RNA tumor viruses – Causes tumors and leukemia Double-stranded RNA, non-enveloped • Reovirus – Mild respiratory infections • Rotavirus – gastroenteritis