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Chapter 12
1.What is the function and structure of DNA?
Function: To store & transmit genetic information
Structure: Double helix made of nucleotides (3 parts)
1. 5-carbon sugar
2. Phosphate
3. Base
2. What are the 4 bases in DNA?
Bases:
Purines
Adenine
Guanine
Pyrimidines
Thymine
Cytosine
hydrogen bonds
2. What are the 4 bases in DNA?
Guanine
3. Which bases always pair together?


Adenine (A) pairs with
Thymine (T)
• Double hydrogen
bond
Guanine (G) pairs with
Cytosine (C)
• Triple Hydrogen
bond
4. How does DNA replicate itself?
 Remember: Which phase of the cell cycle
is replication occurring in?



S (Synthesis) Phase – part of interphase
Must happen before a cell divides (Mitosis)
Results in two exact copies of DNA
4. How does DNA replicate itself?
1. Helicase enzyme unzips
DNA
2. DNA Polymerase attaches
complementary base pairs
DNA =
NEW CHAIN=
A-T-T-C-C-G
T-A-A-G-G-C
3. Each DNA molecule has 1/2
old & 1/2 new
4. Semi-conservative
Replication
4. How does DNA replicate itself?
Chapter Molecular Genetics
12
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