Download Chromosomal Abnormality Notes (11.3)

Chromosomal Abnormalities (11.3)
State Standard
2C. Using Mendel’s laws, explain the role of
meiosis in reproductive variability.
2D. Describe the relationships between changes
in DNA and potential appearance of new traits
Chapter 11
Complex Inheritance and Human Heredity
11.3 Chromosomes and Human Heredity
Karyotype Studies
 ____________—micrograph in which the
__________ of homologous chromosomes
are arranged in decreasing size.
 Images of chromosomes stained during
metaphase
 Chromosomes are arranged in decreasing
size to produce a micrograph.
 Used to identify chromosome ____________
Normal Karyotype
Chapter 11
Complex Inheritance and Human Heredity
11.3 Chromosomes and Human Heredity
Nondisjunction
 Cell division during which sister chromatids
fail to _______________ properly
Nondisjunction on ____________ (non-sex
chromosomes – 1-22) can cause:
 Down Syndrome (Trisomy ______)
 Patau Syndrome (Trisomy ______)
 Edwards Syndrome (Trisomy ______)
Chapter 11
Complex Inheritance and Human Heredity
11.3 Chromosomes and Human Heredity
Nondisjunction Cont’d
 Nondisjunction on ______ chromosomes
can cause…
 _______________ Syndrome (female w/ only 1
X chromosome
 _______________ Syndrome (male w/ an
extra X chromosome
Nondisjunction
Chapter 11
Complex Inheritance and Human Heredity