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Chapter 19 The Blood Hematocrit Substances in Blood Plasma • • • • • • • • • Water Albumins Globulins Fibrinogen Electrolytes Nutrients Gases Regulatory substances Waste products Red Blood Cell Production Terms • Hemopoiesis • Erythropoietin – secreted by kidneys • Erythropoiesis • Hypoxia • Polycythemia Hemoglobin RBC Regulation Types of WBC’s Granular and Agranular Functions of WBC’s • Neutrophils – Phagocytosis using lysozymes, defensins, and oxidants. • Eosinophils - destroy parasites and combat histamines. • Basophils – release heparin, histamine, and serotonin. • Monocytes – Phagocytosis, clean cellular debris. • Lymphocytes – B-cells, T-cells and NK-cells. Diapedesis of WBC’s WBC Terms • • • • Leukocytosis – above normal Leukopenia – below normal Phagocytosis Differential count Platelet Plug Blood clot Platelet Terms • • • • • • • Thrombopoietin Thrombocyte Hemostasis Anticoagulants (Heparin & Warfarin) Thrombus Embolus Thrombocytopenia Clotting cascade Blood Types Rh Factor Anemias • • • • • • Iron deficiency Pernicious (Low B12) Hemorrhagic Hemolytic Thalassemia Aplastic (loss of marrow) Sickle Cell Words to Know • • • • • • • Hemophilia Leukemia Autologous transfusion Cyanosis Hemochromatosis Jaundice Septicemia
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