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Thrombosis in the setting of obesity or inflammatory bowel disease by Steven R. Lentz Blood Volume 128(20):2388-2394 November 17, 2016 ©2016 by American Society of Hematology Influence of obesity and IBD on the relative risk of a first episode of VTE. (A) Meta-analysis of the influence of obesity (BMI >30 mg/m2) on VTE risk. Steven R. Lentz Blood 2016;128:2388-2394 ©2016 by American Society of Hematology Influence of clinical factors, including obesity and IBD, on the relative risk (RR) of recurrent VTE. Risk estimates are taken from the World Health Organization5, Ageno et al,10 and Kearon and Akl.13 The lengths of the bars represent rough approximations o... Steven R. Lentz Blood 2016;128:2388-2394 ©2016 by American Society of Hematology Proposed mechanisms of thrombosis in obesity. Steven R. Lentz Blood 2016;128:2388-2394 ©2016 by American Society of Hematology Proposed mechanisms of thrombosis in IBD. IBD predisposes to thrombosis by inducing episodes of acute and chronic intestinal inflammation, leading to a systemic prothrombotic state characterized by upregulation of tissue factor, an elevated platelet count, ... Steven R. Lentz Blood 2016;128:2388-2394 ©2016 by American Society of Hematology