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_________________ 1 Overview • _______________– process where chemical bonds between atoms are broken or formed to produce one or more ____________ substances. NaCl Reactants Na+ + ClProducts • Starting a chemical rxn requires ___________ ________. • Activation energy – _________ needed to ________ a chemical rxn. ( a chemical _______) 2 What are_____________? • _________ are substances called biological ___________ that speed up chemical rxns by ___________ the activation energy of the rxns. • Enzymes are __________ proteins. • Help regulate __________ reactions. • Help maintain _______________ as metabolic reactions in living things would not occur quickly enough to sustain life. 3 _________ amount of energy needed to start RxN. 4 How do Enzymes ________? • Enzymes work like a _______ and _______. That is, only an enzyme of a specific shape can fit the reactants of the reaction that it is catalyzing. – This works like a ________ piece. ______ enzyme for ______ substrate. • The ___________ an enzyme works on is called a ________________. • The substrate _______ to the ____________to make the enzyme active. • When bound, they make an ‘_________________ ____________’. 5 • Enzymes that are proteins will have a ___ ________________shape • _____________ are the substance which the enzyme ______ upon. 6 Enzymes and Substrates work as ‘________and ______” - only one enzyme will work for each substrate 7 A enzyme & substrate fit like a lock & key (___________ specific) and like a _______ in a _______ – “_________ _______” _____________is where the reactants bind to the enzyme 8 Enzymes usually end in ________ Enzymes in Digestion : Substrate - Trypsin : ________ - Pepsin : __________ - Lipase : __________ - Maltase : ___________ - Protease : ____________ REMEMBER!!!! - Lactase : _____________ -ASE = ________ _________ will tell you what substrate enzyme worked on. ______________ Some enzymes need a non-protein component called a ___________ in order to allow binding of the substrates. In these cases, if the coenzyme is _____ present, the enzyme will not ____________. _______ of ____________ -How much _______ or ________ (NRG) it takes to make the reaction occur NRG activation chart. _________ which affect the Rate of RXN _____________ -_______ -_____________ _______________-_ The __________ where an enzyme works ______ is called _____________________. If the temperature is __________ or _________ the optimal temp, the rate of reaction will____________. _____ as a factor of rate of RXN The pH scale measure the amount of _________ ions in a ____________. _______________ Rate of enzyme rxn also depends on the _____________ of the __________. All available active sites filled __________________ • ____________ containing enzymes that ________worn out organelles, bacteria, or viruses • when a cell dies its lysosomes burst and break down the cell into ______________ that are _________ by other cells • are part of the ___________________ system. • The __________________ Reticulum (synthesis and transport) connects with the _________Appartus (molecule packaging) which makes the lysosomes 20