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Chapter Two: The Systems of the Body Copyright © 2015 McGraw-Hill Education. All rights reserved. No reproduction or distribution without the prior written consent of McGraw-Hill Education. •The nervous system •The endocrine system •The cardiovascular system •The respiratory system •The digestive system and the metabolism of food Copyright © 2015 McGraw-Hill Education. All rights reserved. No reproduction or distribution without the prior written consent of McGraw-Hill Education. 2 •The renal system •The reproductive system •Genetics and health •The immune system Copyright © 2015 McGraw-Hill Education. All rights reserved. No reproduction or distribution without the prior written consent of McGraw-Hill Education. 3 Copyright © 2015 McGraw-Hill Education. All rights reserved. No reproduction or distribution without the prior written consent of McGraw-Hill Education. 4 ( Source: Lankford, 1979, p. 232) Copyright © 2015 McGraw-Hill Education. All rights reserved. No reproduction or distribution without the prior written consent of McGraw-Hill Education. 5 Parts of hindbrain • Medulla: Regulates heart rate, blood pressure, and respiration • Pons: Helps control respiration • Cerebellum: Coordinates voluntary muscle movement and maintenance of: • Balance and equilibrium • Muscle tone and posture Midbrain • Responsible for the coordination of visual and auditory reflexes Copyright © 2015 McGraw-Hill Education. All rights reserved. No reproduction or distribution without the prior written consent of McGraw-Hill Education. 6 Parts of forebrain • Thalamus • Hypothalamus • Cerebral cortex Limbic system • Plays an important role in stress and emotional responses • Amygdala - Detection of threat • Hippocampus - Emotionally charged memories • Areas in the hypothalamus - Emotional functioning Copyright © 2015 McGraw-Hill Education. All rights reserved. No reproduction or distribution without the prior written consent of McGraw-Hill Education. 7 Epilepsy Cerebral palsy Parkinson’s disease Multiple sclerosis Huntington’s disease Polio Paraplegia Quadriplegia Dementia Copyright © 2015 McGraw-Hill Education. All rights reserved. No reproduction or distribution without the prior written consent of McGraw-Hill Education. 8 Copyright © 2015 McGraw-Hill Education. All rights reserved. No reproduction or distribution without the prior written consent of McGraw-Hill Education. 9 •Ductless glands that secrete hormones into the blood and stimulate changes in target organs •Regulated by: • Hypothalamus • Pituitary gland: Consists of the posterior pituitary lobe and the anterior pituitary lobe Copyright © 2015 McGraw-Hill Education. All rights reserved. No reproduction or distribution without the prior written consent of McGraw-Hill Education. 10 Copyright © 2015 McGraw-Hill Education. All rights reserved. No reproduction or distribution without the prior written consent of McGraw-Hill Education. 11 •Diabetes - Body becomes incapable of manufacturing or properly using insulin • Forms • Type I diabetes - Autoimmune disorder • Type II diabetes - Disease of lifestyle Copyright © 2015 McGraw-Hill Education. All rights reserved. No reproduction or distribution without the prior written consent of McGraw-Hill Education. 12 Copyright © 2015 McGraw-Hill Education. All rights reserved. No reproduction or distribution without the prior written consent of McGraw-Hill Education. 13 •Left atrium and left ventricle - Takes in oxygenated blood from the lungs and pumps it out into the aorta •Right atrium and right ventricle - Pumps blood back to the lungs via the pulmonary artery •Cardiac cycle - Regular rhythmic phases of contraction and relaxation • Phases - Systole and diastole Copyright © 2015 McGraw-Hill Education. All rights reserved. No reproduction or distribution without the prior written consent of McGraw-Hill Education. 14 •Atherosclerosis: Arteries are narrowed by plaques formed by deposits of cholesterol and other substances • Angina pectoris: Heart has insufficient supply of oxygen or adequate removal of carbon dioxide and other waste products • Myocardial infarction (MI): Clot in a coronary vessel blocking the flow of blood to the heart Copyright © 2015 McGraw-Hill Education. All rights reserved. No reproduction or distribution without the prior written consent of McGraw-Hill Education. 15 • Ischemia: Characterized by lack of blood flow and oxygen to the heart muscle • Congestive heart failure (CHF) - Heart’s delivery of oxygen-rich blood is inadequate • Arrhythmia - Irregular beatings of the heart leading to loss of consciousness and sudden death •Rheumatic fever: Bacterial infection that originates in the connective tissue Copyright © 2015 McGraw-Hill Education. All rights reserved. No reproduction or distribution without the prior written consent of McGraw-Hill Education. 16 •Force that blood exerts against the blood vessel walls •Highest during systole •Lowest during diastole •Influenced by: • Cardiac output • Peripheral resistance • Structure of the arterial walls Copyright © 2015 McGraw-Hill Education. All rights reserved. No reproduction or distribution without the prior written consent of McGraw-Hill Education. 17 •Plasma - Contains plasma proteins, plasma electrolytes, and the substances transported by the blood •Cells - Contains white blood cells, lymphocytes, red blood cells, and platelets • Platelets: Block small holes that develop in blood vessels and play an important role in blood clotting Copyright © 2015 McGraw-Hill Education. All rights reserved. No reproduction or distribution without the prior written consent of McGraw-Hill Education. 18 •Brings in oxygen through inspiration • Causes the lungs to expand inside the thorax •Eliminates carbon dioxide through expiration • Reduces the lungs’ volume within the thorax Copyright © 2015 McGraw-Hill Education. All rights reserved. No reproduction or distribution without the prior written consent of McGraw-Hill Education. 19 (Source: Lankford, 1979, p. 467) Copyright © 2015 McGraw-Hill Education. All rights reserved. No reproduction or distribution without the prior written consent of McGraw-Hill Education. 20 Hay fever Asthma Viral and bacterial infections Chronic obstructive pulmonary disease Pneumonia Tuberculosis and pleurisy Lung cancer Copyright © 2015 McGraw-Hill Education. All rights reserved. No reproduction or distribution without the prior written consent of McGraw-Hill Education. 21 ( Source: Lankford, 1979, p. 523) Copyright © 2015 McGraw-Hill Education. All rights reserved. No reproduction or distribution without the prior written consent of McGraw-Hill Education. 22 •Gastric secretions in the stomach help with the digestion of food •Enzymes in the small intestine breakdown proteins to amino acids •Large intestine stores food residue and helps in the reabsorption of water •Entry of feces into the rectum leads to the expulsion of solid waste Copyright © 2015 McGraw-Hill Education. All rights reserved. No reproduction or distribution without the prior written consent of McGraw-Hill Education. 23 Gastroesophageal reflux disease Gastroenteritis, diarrhea, and dysentery Peptic ulcer Appendicitis Hepatitis Copyright © 2015 McGraw-Hill Education. All rights reserved. No reproduction or distribution without the prior written consent of McGraw-Hill Education. 24 ( Source: Lankford, 1979, p. 585) Copyright © 2015 McGraw-Hill Education. All rights reserved. No reproduction or distribution without the prior written consent of McGraw-Hill Education. 25 •Kidneys - Regulate the bodily fluids • Produce urine which maintains water balance, blood pH, and electrolyte balance •Ureters - Moves urine to the bladder •Urinary bladder - Reservoir for urine • Urethra - Conducts urine from the bladder out of the body Copyright © 2015 McGraw-Hill Education. All rights reserved. No reproduction or distribution without the prior written consent of McGraw-Hill Education. 26 •Urinary tract infections •Glomerular nephritis •Tubular necrosis •Kidney failure - Could require an artificial kidney, a kidney transplant, or kidney dialysis • Kidney dialysis: Cleanses the blood to remove excess salts, water, and metabolites Copyright © 2015 McGraw-Hill Education. All rights reserved. No reproduction or distribution without the prior written consent of McGraw-Hill Education. 27 ( Sources: Green, 1978, p. 122; Lankford, 1979, p. 688) Copyright © 2015 McGraw-Hill Education. All rights reserved. No reproduction or distribution without the prior written consent of McGraw-Hill Education. 28 Ovaries • Ovum - Produced each month by one ovary • Develops into a human being if fertilized • Flushed out if not fertilized • Estrogen - Develops secondary sex characteristics • Progesterone - Produced during second half of menstrual cycle • Declines if pregnancy fails to occur Testes • Testosterone - Produced by the interstitial cells • Produces sperm • Pass through the uterus into fallopian tubes to fertilize ovum • Develops secondary sex characteristics Copyright © 2015 McGraw-Hill Education. All rights reserved. No reproduction or distribution without the prior written consent of McGraw-Hill Education. 29 Sexually transmitted diseases Chronic pelvic inflammatory disease (PID) in women Cancer Disorders of the menstrual cycle Fertility problems Copyright © 2015 McGraw-Hill Education. All rights reserved. No reproduction or distribution without the prior written consent of McGraw-Hill Education. 30 •Sex chromosomes determines the gender • X chromosome - Mother • X or Y chromosome - Father •Types of research that demonstrates whether a characteristic is genetically acquired • Studies of families • Twin research • Studies of adopted children Copyright © 2015 McGraw-Hill Education. All rights reserved. No reproduction or distribution without the prior written consent of McGraw-Hill Education. 31 •Infection causing microbes can spread via: • Direct transmission • Indirect transmission • Biological transmission • Mechanical transmission Copyright © 2015 McGraw-Hill Education. All rights reserved. No reproduction or distribution without the prior written consent of McGraw-Hill Education. 32 •Whether a microbe produces infection or not depends on: • Number of organisms and their virulence • Body’s defensive capacities •Course • Incubation period • Nonspecific symptoms period • Acute phase Copyright © 2015 McGraw-Hill Education. All rights reserved. No reproduction or distribution without the prior written consent of McGraw-Hill Education. 33 •Body’s resistance to invading organisms •Natural immunity • Acquired through disease • Passed from the mother to the child at birth and through breast-feeding •Artificial immunity - Acquired through vaccinations and inoculations Copyright © 2015 McGraw-Hill Education. All rights reserved. No reproduction or distribution without the prior written consent of McGraw-Hill Education. 34 Nonspecific immune mechanisms • General set of responses to any kind of infection or disorder • Ways of occurring • Anatomical barriers • Phagocytosis • Antimicrobial substances • Inflammatory responses Specific immune mechanisms • Acquired after birth • Fight particular microorganisms and their toxins Copyright © 2015 McGraw-Hill Education. All rights reserved. No reproduction or distribution without the prior written consent of McGraw-Hill Education. 35 (Source: Roitt, Brostoff, & Male, 1998) Copyright © 2015 McGraw-Hill Education. All rights reserved. No reproduction or distribution without the prior written consent of McGraw-Hill Education. 36 Copyright © 2015 McGraw-Hill Education. All rights reserved. No reproduction or distribution without the prior written consent of McGraw-Hill Education. 37 Humoral immunity • B lymphocytes - Confer immunity by the production and secretion of antibodies Cell-mediated immunity • T lymphocytes - Kill invading organisms and infected cells Lymphatic system • Drainage system of the body Copyright © 2015 McGraw-Hill Education. All rights reserved. No reproduction or distribution without the prior written consent of McGraw-Hill Education. 38 •Lupus: Leads to chronic inflammation •Tonsillitis •Infectious mononucleosis •Lymphoma •Autoimmunity: Body attacks its own tissues Copyright © 2015 McGraw-Hill Education. All rights reserved. No reproduction or distribution without the prior written consent of McGraw-Hill Education. 39