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Stage 10 Human Embryo (~ 22 Days)
Somite Formation from Pre-Somitic Mesoderm
Somite Formation and Hairy Gene expression
Hairy Gene Expression
Homeotic (Hox) Genes
Hox a
Hox b
Hox c
Hox d
Hox Gene Expression Along A/P Axis
(Posterior margin of Hox Genes Expression)
“Hox Code” Concept
Hoxc8 Deletion in Mouse
Forelimb Development
in chick and mouse
Limb Bud Development
Sonichedgehog (Shh) Expression in Limb Bud
Ectopic Application of Shh Protein
Hox Gene Expression in Limb Bud
Hox a genes
Hox d genes
Synpolydactyl Phenotype
Hoxd13 mutation
Digit Formation
Programmed Cell Death
Programmed
Cell Death
Pathway
(BMP?)
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