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0 0 10 0 10 Driver Non−driver genes −1 10 CGC Non−CGC −1 −1 −2 −2 10 10 −3 0.5 1 G 5 10 15 10 0 −3 0.5 1 0 G 5 10 15 10 0 0.5 1 G 5 10 15 0 10 Essential Non−essential −1 10 10 DNA repair genes Non−DNA repair genes −1 10 −2 C 10 C 0 −2 10 −3 10 C 10 C 10 C 10 CRF Non−CR F −2 10 −3 10 −4 10 0 −3 0.5 1 G 5 10 15 10 0 0.5 1 G 5 10 15 Fig. S7. The complementary cumulative distribution (C) of the gene-gene gravitation score (G) for five different gene sets: cancer driver gene (Driver), Cancer Gene Census (CGC), chromatin regulation factors (CRF), essential genes, and DNA repair genes in lung adenocarcinoma (LUAD). The number of gene-gene pairs for blue line is equal to red line by random sampling 100 times. The shadow of blue line represent the standard deviation.