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The transcription factors Scl and Lmo2 act together during development of the hemangioblast in zebrafish by Lucy J. Patterson, Martin Gering, Craig E. Eckfeldt, Anthony R. Green, Catherine M. Verfaillie, Stephen C. Ekker, and Roger Patient Blood Volume 109(6):2389-2398 March 15, 2007 ©2007 by American Society of Hematology Lmo2 morphants exhibit normal gross morphology but lack hematopoietic gene expression. Lucy J. Patterson et al. Blood 2007;109:2389-2398 ©2007 by American Society of Hematology Lmo2 atgMO-mediated knockdown of Lmo2 expression is highly specific. Lucy J. Patterson et al. Blood 2007;109:2389-2398 ©2007 by American Society of Hematology Lmo2 is a critical regulator of PLM development. Lucy J. Patterson et al. Blood 2007;109:2389-2398 ©2007 by American Society of Hematology Lmo2 is a critical regulator of ALM development. Lucy J. Patterson et al. Blood 2007;109:2389-2398 ©2007 by American Society of Hematology Endothelial development is severely disrupted in Lmo2-depleted embryos. Lucy J. Patterson et al. Blood 2007;109:2389-2398 ©2007 by American Society of Hematology Scl DNA binding is not required for early erythroid, myeloid, or endothelial gene expression. Lucy J. Patterson et al. Blood 2007;109:2389-2398 ©2007 by American Society of Hematology Lmo2 binding is required for early erythroid, myeloid, and endothelial gene expression. Lucy J. Patterson et al. Blood 2007;109:2389-2398 ©2007 by American Society of Hematology Genetic regulatory networks controlling early PLM and ALM development. Lucy J. Patterson et al. Blood 2007;109:2389-2398 ©2007 by American Society of Hematology
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