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Molecular characterization of the recurrent unbalanced translocation der(1;7)(q10;p10) by Lili Wang, Seishi Ogawa, Akira Hangaishi, Ying Qiao, Noriko Hosoya, Yasuhito Nanya, Kazuma Ohyashiki, Hideaki Mizoguchi, and Hisamaru Hirai Blood Volume 102(7):2597-2604 October 1, 2003 ©2003 by American Society of Hematology Partial karyotype of der (1;7)(q10;p10). Lili Wang et al. Blood 2003;102:2597-2604 ©2003 by American Society of Hematology Representative results of 2-color FISH experiments and comparison of signal intensities in centromere alphoids. Lili Wang et al. Blood 2003;102:2597-2604 ©2003 by American Society of Hematology FISH analysis with the patients using various centromeric alphoid probes. Lili Wang et al. Blood 2003;102:2597-2604 ©2003 by American Society of Hematology Breakpoint mapping in der(1;7)(q10;p10) and proposed mechanism generating this translocation. Lili Wang et al. Blood 2003;102:2597-2604 ©2003 by American Society of Hematology Relative reduction of D1Z7 and D7Z1 contents on the derivative chromosome in different samples. Lili Wang et al. Blood 2003;102:2597-2604 ©2003 by American Society of Hematology Similarity of the 2 involved alphoid subsets. Lili Wang et al. Blood 2003;102:2597-2604 ©2003 by American Society of Hematology