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Molecular profiling of CD34+ cells identifies low expression
of CD7, along with high expression of proteinase 3 or
elastase, as predictors of longer survival in patients with
CML
by Agnes S. M. Yong, Richard M. Szydlo, John M. Goldman, Jane F. Apperley, and
Junia V. Melo
Blood
Volume 107(1):205-212
January 1, 2006
©2006 by American Society of Hematology
Hierarchical clustering using microarray expression measures on 20 most significantly different
genes, represented by 25 probe sets, in 19 patient samples.
Agnes S. M. Yong et al. Blood 2006;107:205-212
©2006 by American Society of Hematology
Representative scatter plots showing a good correlation between the expression of ELA2, PR-3,
and CD7 measured by microarray (MAS 5.0, using an arbitrary scale) and Q-RT/PCR methods (P
values refer to Spearman ρ). .
Agnes S. M. Yong et al. Blood 2006;107:205-212
©2006 by American Society of Hematology
Probability curves based on Cox regression analysis models.
Agnes S. M. Yong et al. Blood 2006;107:205-212
©2006 by American Society of Hematology
Probabilities of survival using CD7 and PR-3 protein expression.
Agnes S. M. Yong et al. Blood 2006;107:205-212
©2006 by American Society of Hematology
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