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Frequent Jumping Translocations of Chromosomal Segments Involving the ABL Oncogene Alone or in Combination With CD3-MLL Genes in Secondary Leukemias by Kimio Tanaka, Mansyur Arif, Mariko Eguchi, Taiichi Kyo, Hiroo Dohy, and Nanao Kamada Blood Volume 89(2):596-600 January 15, 1997 ©1997 by American Society of Hematology (A) Amplified ABL oncogenes in patient no. 4, showing four to six signals in interphase cells. Kimio Tanaka et al. Blood 1997;89:596-600 ©1997 by American Society of Hematology Karyotype from patient 7 shows the complex karyotype, -4 5 , X Y , d e l ( 1 ) ( p 2 2 ) , ;k1 d e l ( 1 ) ( q 1 2 ) ;k4 2 , d e l ( 3 ) ( p 1 1 ) , ;k2 5 , ;k2 7 , d e l ( 1 2 ) ( p 1 1 ) , ;k2 1 6 , ;k2 1 7 , ;k2 1 7 , ;k2 2 0 , ;k1 m a r 1 , ;k1mar2,;k1m... Kimio Tanaka et al. Blood 1997;89:596-600 ©1997 by American Society of Hematology