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Publications for Nikolas Haass Publications for Nikolas Haass 2016 Beaumont, K., Hill, D., Daignault, S., Lui, G., Sharp, D., Gabrielli, B., Weninger, W., Haass, N. (2016). Cell cycle phase-specific drug resistance as an escape mechanism of melanoma cells. The Journal of Investigative Dermatology, 136(7), 1479-1489. <a href="http://dx.doi.org/10.1016/j.jid.2016.02.805 ">[More Information]</a> Haass, N. (2016). Die Rolle der dynamischen Tumorheterogenitat. Spectrum Dermatologie, 2016 (3), 14-17. Skalamera, D., Dahmer-Heath, M., Stevenson, A., Pinto, C., Shah, E., Daignault, S., Said, N., Davis, M., Haass, N., et al (2016). Genome-wide gain-of-function screen for genes that induce epithelial-to-mesenchymal transition in breast cancer. Oncotarget, 7(38), 61000-61020. <a href="http://dx.doi.org/10.18632/oncotarget.113 14">[More Information]</a> Vaidyanathan, S., Cato, K., Tang, L., Pavey, S., Haass, N., Gabrielli, B., Duijf, P. (2016). In vivo overexpression of Emi1 promotes chromosome instability and tumorigenesis. Oncogene, 35(41), 5446-5455. <a href="http://dx.doi.org/10.1038/onc.2016.94">[ More Information]</a> Haass, N. (2016). JNK-ERK signalling in melanoma: rewired or entangled? British Journal of Dermatology, 175(6), 1139-1140. <a href="http://dx.doi.org/10.1111/bjd.14903">[Mo re Information]</a> Giles, K., Brown, R., Ganda, C., Podgorny, M., Candy, P., Wintle, L., Richardson, K., Kalinowski, F., Stuart, L., Epis, M., Haass, N., et al (2016). microRNA-7-5p inhibits melanoma cell proliferation and metastasis by suppressing RelA/NF-(kappa)B. Oncotarget, 7(22), 31663-31680. <a href="http://dx.doi.org/10.18632/oncotarget.942 1">[More Information]</a> Maadi, H., Moshtaghian, A., Taha, M., Mowla, S., Kazeroonian, A., Haass, N., Javeri, A. (2016). Multimodal tumor suppression by miR-302 cluster in melanoma and colon cancer. The International Journal of Biochemistry and Cell Biology, 81, 121-132. <a href="http://dx.doi.org/10.1016/j.biocel.2016.11. 004">[More Information]</a> 2015 Ravindran Menon, D., Das, S., Krepler, C., Vultur, A., Rinner, B., Schauer, S., Kashofer, K., Wagner, K., Zhang, G., Bonyadi Rad, E., et al (2015). A stress-induced early innate response causes multidrug tolerance in melanoma. Oncogene, 34(34), 4448-4459. <a href="http://dx.doi.org/10.1038/onc.2014.372">[ More Information]</a> Spoerri, L., Oo, Z., Larsen, J., Haass, N., Gabrielli, B., Pavey, S. (2015). Cell Cycle Checkpoint and DNA Damage Response Defects as Anticancer Targets: From Molecular Mechanisms to Therapeutic Opportunities. In Georg T. Wondrak (Eds.), Stress Response Pathways in Cancer: From Molecular Targets to Novel Therapeutics, (pp. 29-49). Dordrecht: Springer Science+Business Media. Haass, N. (2015). Dynamic tumor heterogeneity in melanoma therapy: how do we address this in a novel model system? Melanoma Management, 2(2), 93-95. Burke, M., Morais, C., Oliver, K., Lambie, D., Gobe, G., Carroll, R., Staatz, C., Sinnya, S., Soyer, P., Winterford, C., et al (2015). Expression of Bcl-xL and Mcl-1 in the Nonmelanoma Skin Cancers of Renal Transplant Recipients. American Journal of Clinical Pathology, 143(4), 514-526. <a href="http://dx.doi.org/10.1309/AJCPQNB5WA 3PLQBK">[More Information]</a> Tikoo, S., Haass, N. (2015). Friends or foes: IL-10 and TGF-β in melanoma. Experimental Dermatology, 24(4), 254-255. <a href="http://dx.doi.org/10.1111/exd.12661">[Mo re Information]</a> Beaumont, K., Anfosso, A., Ahmed, F., Weninger, W., Haass, N. (2015). Imaging- and Flow Cytometry-based Analysis of Cell Position and the Cell Cycle in 3D Melanoma Spheroids. Journal of Visualized Experiments: JOVE, 28(106), 1-9. <a href="http://dx.doi.org/10.3791/53486">[More Information]</a> Tonnessen, C., Haass, N. (2015). Melanoma: From Tumor-Specific Mutations to a New Molecular Taxonomy and Innovative Therapeutics. In Thomas Bieber, Frank Nestle (Eds.), Personalized Treatment Options in Dermatology, (pp. 7-27). Berlin: Springer-Verlag. Ke, Y., Hummel, A., Stevens, C., Gladbach, A., Ippati, S., Bi, M., Lee, W., Halliday, G., Haass, N., Kiernan, M., et al (2015). Short-term suppression of A315T mutant human TDP-43 expression improves functional deficits in a novel inducible transgenic mouse model of FTLD-TDP and ALS. Acta Neuropathologica, 130(5), 661-678. <a href="http://dx.doi.org/10.1007/s00401-015-148 6-0">[More Information]</a> Haass, N., Nassif, N., McGowan, E. (2015). Publications for Nikolas Haass Switching the sphingolipid rheostat in the treatment of diabetes and cancer comorbidity from a problem to an advantage. BioMed Research International, 2015, 1-9. <a href="http://dx.doi.org/10.1155/2015/165105">[ More Information]</a> 2014 Moloney, F., Guitera, P., Coates, E., Haass, N., Ho, K., Khoury, R., O'Connell, R., Raudonikis, L., Schmid, H., Mann, G., Menzies, S. (2014). Detection of Primary Melanoma in Individuals at Extreme High Risk: A Prospective 5-year Follow-up Study. JAMA Dermatology, 150(8), 819-827. <a href="http://dx.doi.org/10.1001/jamadermatol.20 14.514">[More Information]</a> Hill, D., Lovat, P., Haass, N. (2014). Induction of endoplasmic reticulum stress as a strategy for melanoma therapy:is there a future? Melanoma Management, 1(2), 127-137. <a href="http://dx.doi.org/10.2217/MMT.14.16">[ More Information]</a> Haass, N., Schumacher, U. (2014). Melanoma never says die. Experimental Dermatology, 23(7), 471-472. <a href="http://dx.doi.org/10.1111/exd.12400">[Mo re Information]</a> Beaumont, K., Kumaran - Mohana, N., Haass, N. (2014). Modeling Melanoma In Vitro and In Vivo. Healthcare, 2, 27-46. <a href="http://dx.doi.org/10.3390/healthcare20100 27">[More Information]</a> Haass, N., Beaumont, K., Hill, D., Anfosso, A., Mrass, P., Munoz, M., Kinjyo, I., Weninger, W. (2014). Real-time cell cycle imaging during melanoma growth, invasion and drug response. Pigment Cell & Melanoma Research, 27(5), 764-776. <a href="http://dx.doi.org/10.1111/pcmr.12274">[ More Information]</a> Wang, K., Beaumont, K., Otte, N., Font Sadurni, J., Bailey, C., van Geldermalsen, M., Sharp, D., Tiffen, J., Ryan, R., Jormakka, M., Haass, N., Rasko, J., Holst, J. (2014). Targeting glutamine transport to suppress melanoma cell growth. International Journal of Cancer, 135(5), 1060-1071. <a href="http://dx.doi.org/10.1002/ijc.28749">[Mor e Information]</a> Mohana-Kumaran, N., Hill, D., Allen, D., Haass, N. (2014). Targeting the intrinsic apoptosis pathway as a strategy for melanoma therapy. Pigment Cell & Melanoma Research, 27(4), 525-539. <a href="http://dx.doi.org/10.1111/pcmr.12242">[ More Information]</a> Haass, N. (2014). The Petrel 2014: Annual Report for Southport The Brisbane Seabird Study Group SOSSA, Northern Sector | The Grey-headed Albatross conundrum at the Australian east coast, (pp. 96 - 107). Brisbane, QLD, Australia: SOSSA. 2013 Stehn, J., Haass, N., Bonello, T., Desouza, M., Kottyan, G., Treutlein, H., Zeng, J., Nascimento, P., Sequeira, V., Butler, T., Allanson, M., Winlaw, D., Reeve, V., Weninger, W., et al (2013). A Novel Class of Anticancer Compounds Targets the Actin Cytoskeleton in Tumor Cells. Cancer Research, 73(16), 5169-5182. <a href="http://dx.doi.org/10.1158/0008-5472.CAN -12-4501">[More Information]</a> Tong, P., Qin, J., Cooper, C., Lowe, P., Murrell, D., Kossard, S., Ng, L., Roediger, B., Weninger, W., Haass, N. (2013). A quantitative approach to histopathological dissection of elastin-related disorders using multiphoton microscopy. British Journal of Dermatology, 169(4), 869-879. <a href="http://dx.doi.org/10.1111/bjd.12430">[Mo re Information]</a> Pavey, S., Spoerri, L., Haass, N., Gabrielli, B. (2013). DNA repair and cell cycle checkpoint defects as drivers and therapeutic targets in melanoma. Pigment Cell & Melanoma Research, 26(6), 805-816. <a href="http://dx.doi.org/10.1111/pcmr.12136">[ More Information]</a> Brandner, J., Haass, N. (2013). Melanoma's connections to the tumour microenvironment. Pathology, 45(5), 443-452. <a href="http://dx.doi.org/10.1097/PAT.0b013e328 363b3bd">[More Information]</a> Wroblewski, D., Mijatov, B., Mohana-Kumara, N., Lai, F., Gallagher, S., Haass, N., Zhang, X., Hersey, P. (2013). The BH3-mimetic ABT-737 sensitizes human melanoma cells to apoptosis induced by selective BRAF inhibitors but does not reverse acquired resistance. Carcinogenesis, 34(2), 237-247. <a href="http://dx.doi.org/10.1093/carcin/bgs330">[ More Information]</a> 2012 Smalley, K., Aplin, A., Flaherty, K., Hoeller, C., Bosserhoff, A., Haass, N., Bosenberg, M., Ribas, A., Barnhill, R., Kudchadkar, R., et al (2012). Meeting report from the 2011 International Melanoma Congress, Tampa, Florida. Pigment Cell & Melanoma Research, 25(1), E1-E11. <a href="http://dx.doi.org/10.1111/j.1755-148X.201 1.00943.x">[More Information]</a> Coates, E., Moloney, F., Guitera, P., Haass, N., Ho, K., Khoury, R., Mann, G., Menzies, S. Publications for Nikolas Haass (2012). Melanoma detection in high risk patients: a case series. 20th Regional Conference of Dermatology 2012. Lucas, K., Kumaran - Mohana, N., Lau, D., Zhang, X., Hersey, P., Huang, D., Weninger, W., Haass, N., Allen, J. (2012). Modulation of NOXA and MCL-1 as a Strategy for Sensitizing Melanoma Cells to the BH3-Mimetic ABT-737. Clinical Cancer Research, 18(3), 783-795. <a href="http://dx.doi.org/10.1158/1078-0432.CCR11-1166">[More Information]</a> Moloney, F., Guitera, P., Coates, E., Haass, N., Ho, K., Khoury, R., Mann, G., Menzies, S. (2012). Observation of a five year high risk clinic for primary melanoma. 3rd World Congress of Dermoscopy, Australia. 2011 Kuphal, S., Haass, N. (2011). Cell-Cell and Cell-Matrix Contacts in Melanoma and the Tumor Microenvironment. In Anja Bosserhoff (Eds.), Melanoma Development: Molecular Biology, Genetics and Clinical Application, (pp. 181-215). Vienna: Springer. McGowan, E., Alling, N., Jackson, E., Yagoub, D., Haass, N., Allen, J., Martinello-Wilks, R. (2011). Evaluation of Cell Cycle Arrest in Estrogen Responsive MCF-7 Breast Cancer Cells: Pitfalls of the MTS Assay. PloS One, 6(6), 1-8. <a href="http://dx.doi.org/10.1371/journal.pone.002 0623">[More Information]</a> Hersey, P., Smalley, K., Weeraratna, A., Bosenberg, M., Zhang, X., Haass, N., Paton, E., Mann, G., Scolyer, R. (2011). Meeting report from the 7th International Melanoma Congress, Sydney, November, 2010. Pigment Cell & Melanoma Research, 24(1), e1-e15. <a href="http://dx.doi.org/10.1111/j.1755-148X.201 0.00811.x">[More Information]</a> 2010 de Zwaan, S., Haass, N. (2010). Genetics of basal cell carcinoma. Australasian Journal of Dermatology, 51(2), 81-92; quiz 93-4. <a href="http://dx.doi.org/10.1111/j.1440-0960.200 9.00579.x">[More Information]</a> Haass, N., Ripperger, D., Wladykowski, E., Dawson, P., Gimotty, P., Blome, C., Fischer, F., Schmage, P., Moll, I., Brandner, J. (2010). Melanoma progression exhibits a significant impact on connexin expression patterns in the epidermal tumor microenvironment. Histochemistry and Cell Biology, 133(1), 113-124. <a href="http://dx.doi.org/10.1007/s00418-009-065 4-5">[More Information]</a> Cocciolone, R., Crotty, K., Andrews, L., Haass, N., Moloney, F. (2010). Multiple Desmoplastic Melanomas in Birt-Hogg-Dube Syndrome and a Proposed Signaling Link Between Folliculin, the mTOR Pathway, and Melanoma Susceptibility. Archives of Dermatology, 146(11), 1316-1318. <a href="http://dx.doi.org/10.1001/archdermatol.20 10.333">[More Information]</a> Lee, J., Li, L., Brafford, P., van den Eijnden, M., Halloran, M., Sproesser, K., Haass, N., Smalley, K., Tsai, J., Bollag, G., et al (2010). PLX4032, a potent inhibitor of the B-Raf V600E oncogene, selectively inhibits V600E-positive melanomas. Pigment Cell & Melanoma Research, 23(6), 820-827. <a href="http://dx.doi.org/10.1111/j.1755-148X.201 0.00763.x">[More Information]</a> 2009 Santiago-Walker, A., Li, L., Haass, N., Herlyn, M. (2009). Melanocytes: from morphology to application. Skin Pharmacology and Physiology, 22(2), 114-121. <a href="http://dx.doi.org/10.1159/000178870">[M ore Information]</a> Haass, N., Smalley, K. (2009). Melanoma biomarkers: current status and utility in diagnosis, prognosis, and response to therapy. Molecular Diagnosis and Therapy, 13(5), 283-296. <a href="http://dx.doi.org/10.2165/11317270-00000 0000-00000">[More Information]</a> 2008 Tsai, J., Lee, J., Wang, W., Zhang, J., Cho, H., Mamo, S., Bremer, R., Gillette, S., Kong, J., Haass, N., et al (2008). Discovery of a selective inhibitor of oncogenic B-Raf kinase with potent antimelanoma activity. Proceedings of the National Academy of Sciences of the United States of America (PNAS), 105(8), 3041-3046. <a href="http://dx.doi.org/10.1073/pnas.071174110 5">[More Information]</a> Haass, N. (2008). From xiphophorus to melanoma-a tribute to steven kazianis (1966-2008). Zebrafish, 5(2), 91-92. <a href="http://dx.doi.org/10.1089/zeb.2008.9992"> [More Information]</a> Smalley, K., Lioni, M., Noma, K., Haass, N., Herlyn, M. (2008). In vitro three-dimensional tumor microenvironment models for anticancer drug discovery. Expert Opinion on Drug Discovery, 3(1), 1-10. <a href="http://dx.doi.org/10.1517/17460441.3.1.1" >[More Information]</a> Haass, N., Hoeller, C., Herlyn, M. (2008). Targeting Signaling Pathways - in the search of Melanoma's Achilles' heel. In Menashe Bar-Eli Publications for Nikolas Haass (Eds.), Regulation of Gene Expression in the Tumor Environment, (pp. 27-42). United States: Springer. Haass, N., Sproesser, K., Nguyen, T., Contractor, R., Medina, C., Nathanson, K., Herlyn, M., Smalley, K. (2008). The mitogen-activated protein/extracellular signal-regulated kinase kinase inhibitor AZD6244 (ARRY-142886) induces growth arrest in melanoma cells and tumor regression when combined with docetaxel. Clinical Cancer Research, 14(1), 230-239. <a href="http://dx.doi.org/10.1158/1078-0432.CCR07-1440">[More Information]</a> 2007 Smalley, K., Contractor, R., Haass, N., Kulp, A., Atilla-Gokcumen, G., Williams, D., Bregman, H., Flaherty, K., Soengas, M., Meggers, E., et al (2007). An organometallic protein kinase inhibitor pharmacologically activates p53 and induces apoptosis in human melanoma cells. Cancer Research, 67(1), 209-217. <a href="http://dx.doi.org/10.1158/0008-5472.CAN -06-1538">[More Information]</a> Wenke, A., Kjellman, C., Lundgren-Akerlund, E., Uhlmann, C., Haass, N., Herlyn, M., Bosserhoff, A. (2007). Expression of integrin alpha10 is induced in malignant melanoma. Cellular Oncology, 29(5), 373-386. <a href="http://www.ncbi.nlm.nih.gov/entrez/query. fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract &list_uids=17726260">[More Information]</a> Smalley, K., Contractor, R., Haass, N., Lee, J., Nathanson, K., Medina, C., Flaherty, K., Herlyn, M. (2007). Ki67 expression levels are a better marker of reduced melanoma growth following MEK inhibitor treatment than phospho-ERK levels. British Journal of Cancer, 96(3), 445-449. <a href="http://dx.doi.org/10.1038/sj.bjc.6603596"> [More Information]</a> 2006 Haass, N., Wladykowski, E., Kief, S., Moll, I., Brandner, J. (2006). Differential induction of connexins 26 and 30 in skin tumors and their adjacent epidermis. Journal of Histochemistry and Cytochemistry: imaging the spectrum of cell biology, 54(2), 171-182. <a href="http://dx.doi.org/10.1369/jhc.5A6719.2005 ">[More Information]</a> Smalley, K., Haass, N., Brafford, P., Lioni, M., Flaherty, K., Herlyn, M. (2006). Multiple signaling pathways must be targeted to overcome drug resistance in cell lines derived from melanoma metastases. Molecular Cancer Therapeutics, 5(5), 1136-1144. <a href="http://dx.doi.org/10.1158/1535-7163.MCT -06-0084">[More Information]</a> 2005 Haass, N., Smalley, K., Li, L., Herlyn, M. (2005). Adhesion, migration and communication in melanocytes and melanoma. Pigment Cell Research, 18(3), 150-159. <a href="http://dx.doi.org/10.1111/j.1600-0749.200 5.00235.x">[More Information]</a> Haass, N., Herlyn, M. (2005). Normal human melanocyte homeostasis as a paradigm for understanding melanoma. The journal of investigative dermatology. Symposium proceedings, 10(2), 153-163. <a href="http://dx.doi.org/10.1111/j.1087-0024.200 5.200407.x">[More Information]</a> Smalley, K., Brafford, P., Haass, N., Brandner, J., Brown, E., Herlyn, M. (2005). Up-regulated expression of zonula occludens protein-1 in human melanoma associates with N-cadherin and contributes to invasion and adhesion. The American Journal of Pathology, 166(5), 1541-1554. <a href="http://www.ncbi.nlm.nih.gov/entrez/query. fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract &list_uids=15855653">[More Information]</a>