Download Curriculum Vitae Timothy A Cross

Document related concepts
no text concepts found
Transcript
Curriculum Vitae
Timothy A Cross
December 07, 2016
General Information
University address:
National High Magnetic Field Laboratory
1800 East Paul Dirac Drive
Florida State University
Tallahassee, Florida 32310-4390
Phone: 850-644-0917; Fax: 850-644-1366
E-mail address:
[email protected]
Professional Preparation
1981
Ph.D., University of Pennsylvania. Major: Chemistry.
Timothy A. Cross. (1981). Dynamics of a Viral Coat Protein. Unpublished
doctoral dissertation, University of Pennsylvania.
1976
B.S., Trinity College. Major: Chemistry. Graduated Honors in General
Scholarship (highest academic honor granted by the institution).
Professional Experience
2003–present
Earl Frieden Professor of Chemistry and Biochemistry, Department of
Chemistry & Biochemistry, Florida State University.
1998–present
NMR Spectroscopy and Imaging Program Director, National High Magnetic
Field Lab, Florida State University. 1991-1994 Acting Director NMR
Program 1995-1997 Director for New Initiatives.
1997–present
Courtesy Associate Professor, Department of Biological Science, Florida State
University.
1990–present
Member of the Center for Materials Research and Technology, Florida State
University.
1984–present
Member of the Institute of Molecular Biophysics, Florida State University.
Vita for Timothy A Cross
1984–2007
Director of the FSU Nuclear Magnetic Resonance Facility, Florida State
University. 1984 Institute of Molecular Biophysics.
1984–2003
Assistant, Associate Professor, & Professor, Department of Chemistry &
Biochemistry, Florida State University.
1995–1997
Director for New Initiatives, National High Magnetic Field Laboratory,
Florida State University.
1991–1994
Acting Director of the NMR Program, National High Magnetic Field
Laboratory, Florida State University.
1991–1993
Director of the Institute & Structural Biology Program, Florida State
University.
1983–1984
Postdoctoral Fellow, Department of Biophysical Chemistry, Biozentrum der
Universitat Basel.
1981–1983
Postdoctoral Fellow, Department of Chemistry, University of Pennsylvania.
Honors, Awards, and Prizes
Outstanding Achievements in NMR Spectroscopy, Eastern Analytical Society (2015).
2010 Florida Award, Florida Section of the American Chemical Society (2010). ($500).
2008-Present Fellow of the Biophysical Society, Biophysical Society (2008).
2001-2003 Distinguished Research Professor, Florida State University (2001).
1990-1991 Developing Scholar Award, Florida State University (1990). ($6,000).
1988-1990 Alfred P. Sloan Research Fellow, Alfred P. Sloan Foundation (1988). ($50,000).
1985-1990 Presidential Young Investigator Award, National Science Foundation with matching
support from Proctor & Gamble (1985). ($500,000).
Elected Fellow Status
Elected as a Fellow of International Society for Magnetic Resonance (ISMAR) (2016).
Elected as a Fellow of Biophysical Society (2008).
Elected as a Fellow of American Association for the Advancement of Science (1998).
Fellowship(s)
NATO Postdoctoral Fellowship (1983–1984).
NIH Predoctoral Fellowship (1978–1981).
Page 2
Vita for Timothy A Cross
Current Membership in Professional Organizations
American Association for the Advancement of Science
American Chemical Society
Biophysical Society
Protein Society
Teaching
Courses Taught
General Biochemistry I (BCH4053)
MTB Divisome Complex (BSC4900)
Directed Individual Study (CHM4905)
Directed Individual Study (CHM5833)
Directed Individual Study (CHM5830)
Directed Individual Study (CHM5831)
Directed Individual Study (CHM5832)
Mutations In CRGA (CHM4906)
CrgA Point Mutation (CHM4906)
Membrane Protein Research (CHM4905)
Membrane Protein RS (CHM4905)
Special Topics in Biochemistry and Cell Biology (BCH5886)
Directed Individual Study (MOB5905)
Human Biochemistry (BCH4624)
Directed Individual Study (PHY5909)
Honors Work (CHM4906)
Selected Topics in Biological Science (BSC4933)
Chemical Research (CHM5911)
Chemical Research (CHM5910)
Physical Chemistry of Macromolecules II (CHM5507)
Doctoral Committee Chair
Wright, A. K., graduate. (2016).
Miao, Y., graduate. (2015).
Das, N., graduate. (2014).
Murray, D. T., graduate. (2014).
Sharma, M., graduate. (2010).
Truong, M. L., graduate. (2010).
Moore, J. D., graduate. (2008). Structural and Functional Characterization of the Functional
Domain, Active Site, and Catalytic Mechanism of ChiZ, a Peptidoglycan Hydrolase from
Mycobacterium tuberculosis.
Nguyen, H. T. B., graduate. (2008). Structural Characterization of Rv0008c – An integral
Page 3
Vita for Timothy A Cross
membrane protein from Mycobacterium tuberculosis by solution NMR spectroscopy.
Page, R. C., graduate. (2008). Structural Characterizations of Integral Membrane Proteins: The
Nexus of Solution and Solid State NMR Spectroscopy.
Li, C., graduate. (2007). Membrane Protein Structural and Dynamics Characterization by Static
Solid-State Nuclear Magnetic Resonance Spectroscopy.
Mo, Y., graduate. (2005). Study of Structure-Function Correlations in Ion Channels by
Solid-State NMR.
Hu, J., graduate. (2005). Structure-Function Correlation of the M2 Proton Channel
Characterized by Solid-State Nuclear Magnetic Resonance Spectroscopy.
Tian, C., graduate. (2003). Initial Structural Characterization of Integrated Membrane M2
Proton Channel from Influenza A Virus using Solid-State and Solution NMR.
Kim, S., graduate. (2002). Computational Aspects of Membrane Protein Structural
Determination Using Solid State NMR.
Wang, J., graduate. (2001). PISA Wheel Analysis and M2-TMP Structural Determination.
Kovacs, F., graduate. (1999). Structural Characterization of the M2 Protein Ion Channel of the
Influenza A Virus Using Solid State Nuclear Magnetic Resonance Spetroscopy.
Cotten, M., graduate. (1998). Molecular Basis of Channel Folding and Function in Membranes:
A Solid State NMR Study Featuring Aromatic Amino Acids in a Model System,
Gramicidin A.
Tian, F., graduate. (1998). Structure-Function Correlations of an Ion Channel Probed by Solid
State NMR.
Xu, F., graduate. (1997). Solvent Roles in Polypeptide Structure and Stability.
Ketchem, R., graduate. (1995). Structural Determination and Refinement of the Gramicidin A
Transmembrane Channel as Studied by Solid-State Nuclear Magnetic Resonance
Spectroscopy.
Lee, K. C., graduate. (1994). Novel Structural Constraints and Dynamics in the Gramicidin
Cation Channel.
Hu, W., graduate. (1994). Conformations, Dynamics and Functional Roles for Tryptophans in
the Gramicidin A Transmembrane Channel Studied by Solid-State Nuclear Magnetic
Resonance.
North, C., graduate. (1993). Peptide Backbone Librations of the Gramicidin A Transmembrane
Channel as Measured by Solid State Nuclear Magnetic Resonance: Implications for
Proposed Mechanisms of Ion Transport.
Pascal, S., graduate. (1993). High Resolution Structure Determination of Gramicidin A Dimers
in Various Solvent Environments by 2D 1H-1H NMR.
Nicholson, L., graduate. (1990). The Structural Motif and Backbone Dynamics of
Membrane-Bound Gramicidin-A Using Solid-State 15N Nuclear Magnetic Resonance
Spectroscopy.
Teng, Q., graduate. (1990). Determination of Nuclear Spin Tensor Orientations and their
Application in the Structure Determination of Gramicidin A by Solid State NMR.
Ekanayake, E., doctoral candidate.
Escobar Bravo, C. A., doctoral candidate.
Paulino, J., doctoral candidate.
Shin, Y., doctoral candidate.
Can, T., doctoral student.
Griffin, J. M., doctoral student.
Page 4
Vita for Timothy A Cross
Kozlova, A. S., doctoral student.
Doctoral Committee Member
Spear, J. M., graduate. (2015).
Lu, Y., graduate. (2013).
Porter, C. M., graduate. (2011).
Nguyen, D., graduate. (2008).
Ongley, H., graduate. (2008).
Ruben, E. A., graduate. (2007).
Calvin, K., graduate. (2007).
Achuthan, S., graduate. (2007).
Hall, M., graduate. (2007).
Stavreva, T., graduate. (2007).
Waller, J., graduate. (2007).
Asbury, T., graduate. (2006).
Song, L., graduate. (2006).
Marin, V., graduate. (2005).
Bhatia, S., graduate. (2004).
Buttery, S., graduate. (2004).
Gattis, J., graduate. (2004).
Korostelev, A., graduate. (2004).
Wu, Z., graduate. (2004).
Clark, S. A., graduate. (2003).
Mehndiratta, P., graduate. (2003).
Panagiotakis, M., graduate. (2002).
Sale, K., graduate. (2002).
Soares, A., graduate. (2002).
Cook, K., graduate. (2001).
Callihan, D., graduate. (2000).
Griffin, P., graduate. (2000).
Patterson, B., graduate. (2000).
Xie, Q., graduate. (2000).
DeMaria, J., graduate. (1999).
Nakamae, S., graduate. (1999).
DeLia, T., graduate. (1998).
Meyer, D., graduate. (1998).
Ming, L., graduate. (1998).
Schaab, K., graduate. (1998).
Schmidt, P., graduate. (1998).
Svirschevsky, S., graduate. (1998).
Adhikari, B. B., graduate. (1997).
Combs, C., graduate. (1997).
Drazen, M., graduate. (1996).
Kinsey, S., graduate. (1996).
Page 5
Vita for Timothy A Cross
Su, L., graduate. (1996).
Liu, Zhi-Ren, graduate. (1994).
Merchant, K., graduate. (1994).
Hecker, K. H., graduate. (1993).
Yoo, H., graduate. (1993).
Li, X., doctoral candidate.
Schwartz, A. B., doctoral candidate.
Sternisha, S. M., doctoral candidate.
Corbett, K. M., doctoral student.
Klatsky, J. C., doctoral student.
Throckmorton, R., doctoral student.
Doctoral Committee University Representative
Kaur, P., graduate. (2016).
Bradshaw, M. D., graduate. (2015).
Throckmorton, R. E., graduate. (2012).
Lakner, C., graduate. (2011).
Nguyen, D. N., graduate. (2007).
Black, M., graduate. (1988).
Hu, X., doctoral candidate.
Hayati, Z., doctoral student.
Master's Committee Chair
Gupta, C. C. H., graduate. (2011).
Chase, R., graduate. (2007). Initial Characterization of Two Alpha-Helical Membrane Proteins
from Mycobacterium tuberculosis.
Kim, H., graduate. (2003). Solid State NMR Cross Polarization Schemes for Peptide Samples
Oriented in Hydrated Phospholipid Bilayers.
Mo, Y., graduate. (2002). A Structural Study of Gramicidin A in Long Chain Lipids by Solid
State NMR.
Zhang, L., graduate. (1998). An Investigation of the Protonation of Histidine-37 in Influenza A
Virus M2 Protein by Solid State NMR.
Wang, C., graduate. (1991). The Use of Chemical Shift as a Structural Constraint: Application to
the Gramicidin A Channel Using Solid State NMR.
Fields, C. G., graduate. (1989). The Application of Solid Phase Peptide Synthesis for the Study of
Gramicidins A, B, and C by Solid Sate NMR Spectroscopy.
Moll, F., graduate. (1988). Solid State Phosporus Nuclear Magnetic Resonance Study on
Alignment and Characterization of Oriented Phospholipids Containing Gramicidin D.
LoGrasso, P., graduate. (1988). Solid State 15N NMR of Uniformly 15N Labeled Gramicidin.
Page 6
Vita for Timothy A Cross
Master's Committee Member
Nakamae, S., graduate. (1995).
Yoo, H., graduate. (1994).
Kamasa-Quashie, A. K., graduate. (1993).
Bradshaw, M. D., student.
Bachelor's Committee Member
Bradshaw, M., graduate. (2010).
Kahen, E., graduate. (2009).
Strafstrom, C., graduate. (1995).
Bridgeford, E., graduate. (1994).
Research and Original Creative Work
Publications
Refereed Journal Articles
Fu, R., Miao, Y., & Cross, T. A. (submitted). "Probing Hydronium Ion Histidine NH Exchange
Rates in the M2 Channel via Indirect Observation of Dipolar-Dephased 15N Signal in
Solid State MAS NMR". J. Am. Chem. Soc. Manuscript submitted for publication.
Tzitzoglaki, C., Wright, A., Freudenberger, K., Kolarov, F., Tietjen, I., Fedida, D., Gauglitz, G.,
Cross, T. A., & Kolocouris, A. (submitted). "Binding and Proton Blockage by
Amantadine Variants of the Influenza M2TMWT and M2TMS31N Explained". J. Med.
Chem. Manuscript submitted for publication.
Chekmenev, E., & Cross, T. A. (submitted). Oxygen-17 Chemical Shift Can Probe Ion
Conduction in Native Channel Environment. Manuscript submitted for publication.
Murray, D. T., Lu, Y., Cross, T. A., & Quine, J. R. (submitted). Geometry of Kinked Protein
Helices from NMR Datat. Manuscript submitted for publication.
Plocinski, P., Ziolkiewicz, M., Kiran, M., Nguyen, H., Hugonnet, J., Veckerle, C., Arthur, M.,
Dziadek, J., Cross, T. A., Madiraju, M., & Rajagopalan, M. (submitted). Characteriztion
of CrgA, A New Partner of the Mycobacterium tuberculosis Peptidoglycan
Polymerization Complexes. Manuscript submitted for publication.
Ekanayake, E. V., Fu, R., & Cross, T. A. (2016). Structural Influences: Cholesterol, Drug, and
Proton Binding to Full-Length Influenza A M2 Protein. Biophys J, 110(6), 1391-9.
doi:10.1016/j.bpj.2015.11.3529
Page 7
Vita for Timothy A Cross
Miao, Y., Fu, R., Zhou, H.-X., & Cross, T. A. (2016). Dynamic, Short Hydrogen Bonds in
Histidine Tetrad of Full-Length M2 H+ Channel Reveals Tetrameric Structural
Heterogeneity and Functional Mechanism". Structure, 23, 2300-2308.
Wright, A. K., Batsomboon, P., Dai, J., Hung, I., Zhou, H.-X., Dudley, G. B., & Cross, T. A.
(2016). "Differential Binding of Rimantadine Enantiomers to Influenza A M2 Proton
Channel". J. Am. Chem. Soc, 138, 1506-1509.
Das, N., Dai, J., Hung, I., Rajagopalan, M. R., Zhou, H. X., & Cross, T. A. (2015). Structure of
CrgA, a cell division structural and regulatory protein from Mycobacterium tuberculosis,
in lipid bilayers. Proc Natl Acad Sci U S A, 112(2), E119-26.
doi:10.1073/pnas.1415908112
Markiewicz, W. D., Brey, W. W., Cross, T. A., Dixon, I. R., Gor'kov, P. L., Grant, S. C., Marks,
E. L., Painter, T. A., Schepkin, V. D., & Swenson, C. A. (2015). "A Decade of
Experience with the Ultra-Wide-Bore 900 MHz NMR Magnet". IEEE Trans. Appl.
Supercon, 3, 1-6.
Cross, T. A., Ekanayake, V., Paulino, J., & Wright, A. (2014). Solid state NMR: The essential
technology for helical membrane protein structural characterization. J Magn Reson, 239,
100-9. doi:10.1016/j.jmr.2013.12.006
Jean-Francois, F. L., Dai, J., Yu, J., Myrick, A., Rubin, E., Fajer, P. G., Song, L., Zhou, H.-X., &
Cross, T. A. (2014). "Transmembrane Regulatory Peptides as Potential Drugs for
Tuberculosis: Structural study of MgtR-MgtC interaction". J. Mol. Biol, 426, 436-446.
doi:.org/10.1016/j.jmb.2013.10.014
Kolocouris, A., Tzitzoglaki, C., Johnson, F. B., Zell, R., Wright, A. K., Cross, T. A., Tietjen, I.,
Fedida, D., & Busath, D. D. (2014). "Aminoadamantanes with Persistent in vitro Efficacy
Against H1N1 Influenza A". J. Med. Chem, 57, 4629-4639. doi:10.1021/jm500598u
Miao, Y., Cross, T. A., & Fu, R. (2014). Differentiation of histidine tautomeric states using
(15)N selectively filtered (13)C solid-state NMR spectroscopy. J Magn Reson, 245,
105-9. doi:10.1016/j.jmr.2014.06.005
Murray, D. T., Griffin, J., & Cross, T. A. (2014). "Detergents Optimized Membrane Protein
Reconstitution in Liposomes for Solid State NMR". Biochemistry, 53, 2454-2463.
Murray, D. T., Hung, I., & Cross, T. A. (2014). "Assignment of Oriented Sample NMR
Resonances from a Three-Transmembrane Helix Protein". J. Magn. Reson, 240, 34-44.
Murray, D. T., Li, C., Gao, F. P., Qin, H., & Cross, T. A. (2014). "Structural Validation of
Helical Membrane Proteins by Absolute Restraints from Solid State NMR: Diacyglycerol
Kinase, an example". Biophys. J, 106, 1559-1569.
Page 8
Vita for Timothy A Cross
Cross, T. A., Murray, D. T., & Watts, A. (2013). "Helical Membrane Protein and Their
Environment". European Journal of Biophysics, 42, 731-755.
doi:10.1007/s00249-013-0925-x
Das, N., Murray, D. T., & Cross, T. A. (2013). Lipid bilayer preparations of membrane proteins
for oriented and magic-angle spinning solid-state NMR samples. Nat Protoc, 8(11),
2256-70. doi:10.1038/nprot.2013.129
Dong, H., Yi, M., Cross, T. A., & Zhou, H.-X. (2013). "Ab Initio Calculations and Validation of
the pH-Dependent Structures of the His37-Trp41 Quartet, the Heart of Acid Activation
and Proton Conductance in the M2 Protein of Influenza A Virus". Chem. Sci. RSC, 4,
2776-2787.
Miao, Y., & Cross, T. A. (2013). "Solid State NMR and Protein-Protein Interactions in
Membranes". Curr. Opin. Stuct. Biol, 23, 919-928. doi:org/10.1016/j.sbi.2013.08.004
Miao, Y., Cross, T. A., & Fu, R. (2013). , Cross, T.A. & (2013) "Identifying Inter-Residue
Resonances in Crowded 2D 13C-13C Correlation Spectra of Membrane Proteins by
Solid-State MAS NMR Difference Spectroscopy". J. Magn. Reson, 56, 265-273.
Murray, D., Das, N., & Cross, T. A. (2013). "Solid State NMR Strategy for Characterizing
Native Membrane Protein Structures". Accounts of Chemical Research, 46, 2172-2181.
doi:10.1021/ar3003442
Sharma, M., Yi, M., Dong, H., Qin, H., Busath, D. D., Zhou, H.-X., & Cross, T. A. (2013). "The
Novel Histidine/Tryptophan Chemistry of the M2 Protein of Influenza A". US Patent
8,581,584, 01.
Zhou, H.-X., & Cross, T. A. (2013). "Influences of Membrane Mimetic Environments on
Membrane Protein Structures". Annual Reviews of Biophysics, 42, 361-392.
doi:10.1146/annurev-biophys-083012-130326
Zhou, H.-X., & Cross, T. A. (2013). "Modeling the Membrane for Structural and Functional
Characterization: Influenza A M2 Protein". Protein Science, 22, 381-394.
Can, T. V., Sharma, M., Hung, I., Gor'kov, P. L., Brey, W. W., & Cross, T. A. (2012). "Magic
Angle Spinning and Oriented Sample Solid State NMR Structural Restraints Combine for
Influenxa A M2 Protein Functional Insights". J. Am. Chem. Soc, 134, 9022-9025.
Cross, T. A., T.A., Dong, H., Sharma, M., Busath, D. D., & Zhou, H.-X. (2012). "M2 Protein
from Influenza A: From multiple structures to biophysical and functional insights". Curr.
Opin. Virology, 2, 128-133.
Page 9
Vita for Timothy A Cross
Dong, H., Sharma, M., Zhou, H.-X., & Cross, T. A. (2012). "Glycines:Role in √-Helical
Membrane Protein Structure and Potential for Structural Validation". Biochemistry, 51,
4779-4789.
Du, J., Cross, T. A., & Zhou, H.-X. (2012). "Recent Progress in Structure-Based Anti-Influenza
Drug Design" :. Drug Discov Today, 17, 1111-1120.
Miao, Y., Qin, H., Fu, R., Sharma, M., Can, T. V., Hung, I., Luca, S., Gor'kov, P. L., Brey, W.
W., & Cross, T. A. (2012). "M2 Protein Channel Structural Validation from Full Length
Protein Samples in Synthetic Bilayers and E. coli Membranes". Angew. Chemie, 51,
8383-8386.
Plocinski, P., Arora, N., Sarva, K., Qin, H., Das, N., Plocinska, R., Ziolkiewiz, M., Dziadek, J.,
Kiran, M., Cross, T. A., Madiraju, M., & Rajagopalan. (2012). "Mycobacterium
tuberculosis CwsA Interacts with CrgA ad Wag31 and the CrgA-CwsA complex is
involved in peptidoglycan synthesis and cell shape determination". J. Bact, 194,
6398-6409.
Cross, T. A., Sharma, M., Yi, M., & Zhou, H.-X. (2011). Influence of Solubilizing Environments
on Membrane Protein Structures. Trends Biol. Sci, 36, 117-125.
Hu, J., Qin, H., Gao, F. P., & Cross, T. A. (2011). "A systematic application of mature MBP in
membrane protein production: overexpression, membrane targeting, and purification". J.
Prot. Expr. Purif, 80, 34-40.
Murray, D. T., Lu, Y., Cross, T. A., & Quine, J. R. (2011). "Geometry of Kinked Protein Helices
from NMR Data". J. Magn. Reson, 210, 82-89.
Peterson, E., Ryser, T., Funk, S., Inoye, D., Sharma, M., Qin, H., Cross, T. A., & Busath, D. D.
(2011). Functional Reconstitution of Influenza A M2(22-62). BBA-Biomemb, 1808,
516-552.
Plocinski, P., Ziolkiewicz, M., Kiran, M., Nguyen, H., Hugonnet, J., Veckerle, C., Arthur, M.,
Dziadek, J., Cross, T. A., Madiraju, M., & Rajagopalan, M. (2011). Characteriztion of
CrgA, A New Partner of the Mycobacterium tuberculosis Peptidoglycan Polymerization
Complexes:. J. Bacteriol, 193, 3246-3256.
Separovic, F., Killian, J. A., Cotten, M., Busath, D. D., & Cross, T. A. (2011). "Modeling the
Membrane Environment for Membrane Proteins". Biophys. J, 100, 2073-2074.
Sharma, M., Li, C., Busath, D. D., Zhou, H.-X., & Cross, T. A. (2011). Drug Sensitivity,
Drug-Resistant Mutations, and the Structure of three Conductance Domains of Viral
Porins. BBA-Biomemb, 1808, 2538-2546.
Page 10
Vita for Timothy A Cross
Jones, T. L., Fu, R., Nielsen, F., Cross, T. A., & Busath, D. D. (2010). Gramicidin Channels are
Internally Gated. Biophys. J, 98, 1486-1493.
Sharma, M., Yi, M., Dong, H., Qin, H., Petersen, E., Busath, D. D., Zhou, H.-X., & Cross, T. A.
(2010). Insight into the Mechanism of the Influenza A Proton Channe from a Structure in
a Lipid Bilayer. Science, 330, 509-512.
Cross, T. A. (2009). News and Views: Flu M2B Structure and Function. Nature Structural &
Molecular Biology, 16, 1207-1209.
Hu, J., Qin, H., Gao, F. P., & Cross, T. A. (2009). A systematic application of mature MBP in
membrane protein production: overexpression, membrane targeting, and purification.
Journal of Protein Expression and Purification, 80, 34-40.
Hu, J., Sharma, M., Qin, H., Gao, F. P., & Cross, T. A. (2009). ) Ligand Binding in the
Conserved Interhelical Loop of CorA, a Magnesium channel from Mycobacterium
tuberculosis. J. Biol. Chem, 284, 15619-15628.
Page, R. C., Lee, S., Moore, J. D., Opella, S. J., & Cross, T. A. (2009). Backbone Structure of a
Small Integral Membrane Protein: a unique structural characterization. Prot. Sci, 18,
134-146.
Qian, C., Fu, R., Gor'kov, P., Brey, W. W., Cross, T. A., & Gan, Z. (2009). 14N Polarization
Inversion Spin Exchange at Magic Angle (PISEMA). J. Magn. Reson, 196, 96-99.
Yi, M., Cross, T. A., & Zhou, H.-X. (2009). Conformational heterogeneity of the M2 proteon
channel: a structural model for channel activation. PNAS, 106, 13311-13316.
Achuthan, S., Asbury, T., Hu, J., Bertram, R., Cross, T. A., & Quine, J. R. (2008). Continuity
Conditions and Torsion Angles From ssNMR Orientational Restraints. J. Magn. Reson,
191, 24-30.
Gan, Z., Kwak, H.-T., Bird, M., Cross, T. A., Gor'kov, P., Brey, W. W., & Shetty, K. (2008).
High Field NMR using Resistive and Hybrid Magnets. J. Magn. Reson, 191, 135-140.
Hu, J., Qin, H., Li, C., Sharma, M., Cross, T. A., & Gao, F. P. (2008). Chemical Cleavage of
Fusion Proteins for High Level Production of Transmembrane Peptides and Protein
Domains Containing Conserved Methionines. BBA-Biomembranes, 1778, 1060-1066.
Li, C., Yi, M., Hu, J., Zhou, H.-X., & Cross, T. A. (2008). Solid-State NMR and MD Simulation
of the Anti-Viral Drug Amantadine Solubilized in DMPC Bilayers. Biophys. J, 94,
1295-1302.
Page 11
Vita for Timothy A Cross
Moffat, J. C., Vijayvergiya, V., Gao, P. F., Cross, T. A., Woodbury, D. J., & Busath, D. D.
(2008). Proton Transport Through Influenza Virus A M2 Protein Reconstituted in
Vesicles. Biophys. J, 94, 434-445.
Nguyen, H., & Cross, T. A. (2008). 1H, 15N, and 13C Backbone resonance assignment of
Rv1567c, an integral membrane protein from Mycobacterium tuberculosis. Biomol. NMR
Assign, 2, 47-49.
Page, R. C., Kim, S., & Cross, T. A. (2008). Transmembrane Helix Uniformity Examined by
Spectral Mapping of Torsion Angles. Structure, 16, 787-797.
Qin, H., Hu, J., Hua, Y., Challa, S. V., Cross, T. A., & Gao, F. P. (2008). Construction of a
Series of Vectors for High Throughput Cloning and Expression Screening of membrane
Proteins from Mycobacterium tuberculosis. BMC Biotechnology, 8, 51.
Witter, R., Nozirov, F., Sternberg, U., Cross, T. A., Ulrich, A. S., & Fu, R. (2008). Solid State
19F-NMR Reveals that Trp-41 Participates in the Gating Mechanism of the M2 Proton
Channel from Influenza A Virus. J. Am. Chem. Soc, 103, 918-924.
Yi, M., Cross, T. A., & Zhou, H.-X. (2008). A secondary Gate as a Mechanism for Inhibition of
the M2 Proton Channel by Amantadine. J. Phys. Chem. B, 112, 7977-7979.
Fu, R., Truong, M., Saager, R. J., Cotten, M., & Cross, T. A. (2007). High Resolution
Heteronuclear Correlation Spectroscopy in Solid State NMR of Aligned Samples. J.
Magn. Reson, 188, 41-48.
Hu, J., Asbury, T., Achuthan, S., Li, C., Bertram, R., Quine, J. R., Fu, R., & Cross, T. A. (2007).
Backbone Structure of the Amantadine-blocked Transmembrane Domain M2 Proton
Channel from Influenza A Virus. Biophys. J, 92, 4335-4343.
Hu, J., Fu, R., & Cross, T. A. (2007). The Chemical and Dynamical Influence of the Anti-Viral
Drug Amantadine on the M2 Proton Channel Transmembrane Domain. Biophys. J, 93,
276-283.
Hu, J., Qin, H., Li, C., Sharma, M., Cross, T. A., & Gao, F. P. (2007). Structural Biology of
Transmembrane Domains: Effieicient Production and Characterization of
Transmembrane Peptides by NMR. Prot. Sci, 16, 2153-2165.
Korepanova, A., Nguyen, H., Hua, Y., Moore, J., & Cross, T. A. (2007). Expression of
Membrane Proteins from Mycobacterium tuberculosis in Escherichia coli as Fusions with
Maltose Binding Protein. Prot. Express. Purif, 53, 24-30.
Li, C., Gao, F. P., Qin, H., Chase, R., Gor'kov, P. L., Brey, W. W., & Cross, T. A. (2007).
Uniformly Aligned Full-Length Membrane Proteins in Liquid-Crystalline Bilayers for
Structural Characterization. J. Am. Chem. Soc, 129, 5304-5305.
Page 12
Vita for Timothy A Cross
Li, C., Qin, H., Gao, F. P., & Cross, T. A. (2007). Solid-State NMR Characterization of
Conformational Plasticity within the Transmembrane Domain of the Influenza A M2
Proton Channel. BBA, Biomembranes, 1768, 3162-3170.
Page, R., Li, C., Hu, J., Gao, F. P., & Cross, T. A. (2007). Lipid Bilayers: An Essential
Environment for the Understanding of Membrane Proteins. Magn. Reson. Chem, 45,
S2-S11.
Asbury, T., Quine, J. R., Achuthan, S., Hu, J., Chapman, M. S., Cross, T. A., & Bertram, R.
(2006). PIPATH: An Optimized Algorithm for Generating a-Helical Structures from
PISEMA Data. J. Magn. Reson, 183, 87-95.
Chekmenev, E. Y., Gor'kov, P. L., Cross, T. A., Alaouie, A. M., & Smirnov, A. I. (2006).
Flow-through Lipid Nanotube Arrays for Structure-Function Studies of Membrane
Proteins by Solid-State NMR Spectroscopy. Biophys. J, 91, 3076-3084.
Chekmenev, E. Y., Waddell, K. W., Hu, J., Gan, Z., Wittebort, R. J., & Cross, T. A. (2006). Ion
Binding Study by 17O Solid-State NMR Spectroscopy in a Model Peptide Gly-Gly-Gly
at 19.6 T. J. Am. Chem. Soc, 128, 9849-9855.
Gor'kov, P. L., Chekmenev, E. Y., Fu, R., Hu, J., Cross, T. A., Cotten, M., & Brey, W. W.
(2006). A Large Volume Flat Coil Probe for Oriented Membrane Proteins. J. Magn.
Reson, 180, 9-20.
Hu, J., Fu, R., Nishimura, K., Zhang, L., Zhu, H.-X., Busath, D. D., Vijayvergiya, V., & Cross,
T. A. (2006). Histidines: Heart of the H+ Channel from Influenza A Virus. Proc. Natl.
Acad. Sci. USA, 103, 6865-6870.
Li, C., Mo, Y., Hu, J., Chekmenev, E., Tian, C., Gao, F. P., Fu, R., Gor'kov, P., Brey, W., &
Cross, T. A. (2006). Analysis of RF Heating and Sample Stability in Aligned Static
Solid-State NMR Spectroscopy. J. Magn. Reson, 180, 51-57.
Page, R. C., Moore, J. D., Nguyen, H. B., Sharma, M., Chase, R., Gao, F. P., Mobley, C. K.,
Sanders, C. R., Ma, L., Sonnichsen, F. D., Lee, S., Howell, S. C., Opella, S. J., & Cross,
T. A. (2006). Comprehensive Evaluation of Solution Nuclear Magnetic Resonance
Spectroscopy Sample Preparation for Helical Integral Membrane Proteins. J. Struct.
Funct. Genomics, 7, 51-64.
Quine, J. R., Achuthan, S., Asbury, T., Bertram, R., Chapman, M. S., Hu, J., & Cross, T. A.
(2006). Intensity and Mosaic Spread Analysis from PISEMA Tensors in Solid State
NMR. J. Magn. Reson, 179, 190-198.
Page 13
Vita for Timothy A Cross
Chekmenev, E. Y., Hu, J., Gor'kov, P. L., Brey, W. W., Cross, T. A., Ruuge, A., & Smirnov, A.
I. (2005). 15N and 31P Solid-State NMR Study of Transmembrane Domain Alignment of
M2 Protein of Influenza A Virus in Hydrated Cylindrical Lipid Bilayers Confined to
Anodic Aluminum Oxide Nanopores. J. Magn. Reson, 173, 322-327.
Fu, R., Brey, W. W., Shetty, K., Gor'kov, P., Saha, S., Long, J. R., Grant, S. C., Chekmenev, E.
Y., Hu, J., Gan, Z., Sharma, M., Logan, T. M., Brüschweiler, R., Edison, A., Blue, A.,
Dixon, I. R., Markiewicz, W. D., & Cross, T. A. (2005). Ultra-Wide Bore 900 MHz
High-Resolution NMR at the National High Magnetic Field Laboratory. J. Magn. Reson,
177, 1-8.
Gao, F. P., & Cross, T. A. (2005). Recent Developments in membrane Protein Structural
Genomics. Genome Biology, 6, 244.
Hu, J., Chekmenev, E., Gan, Z., Gor'kov, P., Saha, S., Brey, W. W., & Cross, T. A. (2005). Ion
Solvation by Channel Carbonyls Characterized by 17O Solid State NMR at 21 T. J. Am.
Chem. Soc, 127, 11922-11923.
Korepanova, A., Gao, F. P., Hua, Y., Qin, H., Nakamoto, R. K., & Cross, T. A. (2005). Cloning
and Expression of Multiple Integral Membrane Proteins from Mycobacterium
tuberculosis in Escherichia coli. Prot. Sci, 14, 148-158.
Xiong, Y., Chalmers, M. J., Gao, F. P., Cross, T. A., & Marshall, T. A. (2005). Identification of
Mycobacterium tuberculosis H37Rv Integral Membrane Proteins by One-Dimensional
Gel Electrophoresis and Liquid Chromatography Electrospray Ionization Tandem Mass
Spectrometry. J. Proteome Res, 4, 855-861.
Fu, R., Hu, J., & Cross, T. A. (2004). Towards Quantitative Measurements in Solid-State
CPMAS NMR: A Lee-Goldburg Frequency Modulated Cross Polarization Scheme. J.
Magn. Reson, 168, 8-17.
Kim, H., Cross, T. A., & Fu, R. (2004). Cross Polarization Schemes for Peptide Samples
Oriented in Hydrated Phospholipid Bilayers. J. Magn. Reson, 168, 147-152.
Kim, S., & Cross, T. A. (2004). 2D Solid State NMR Spectral Simulations of 310, a, and
p-Helices. J. Magn. Reson, 168, 187-193.
Mo, Y., Cross, T. A., & Nerdal, W. (2004). Structural Restraints and heterogeneous Orientation
of the Gramicidin A Channel Closed State in Lipid Bilayers. Biophysical J, 86,
2837-2845.
Quine, J. R., Chapman, M. S., Cross, T. A., & Bertram, R. (2004). Mathematical Aspects of
Protein Structure Determination with NMR Orientational Restraints. Bull. Math. Biology,
66, 1705-1730.
Page 14
Vita for Timothy A Cross
Schneider-Muntau, H. J., Brandt, B. L., Brunel, L. C., Cross, T. A., Edison, A. S., Marshall, A.
G., & Reyes, A. P. (2004). The National High Magnetic Field Laboratory. Physica
B-Condensed Matter, 346, 643-648.
Vijayvergiya, V., Wilson, R., Chorak, A., Gao, P., Cross, T. A., & Busath, D. D. (2004). Proton
Conductance of Influenza Virus M2 Proteins in Planar Lipid Bilayers. Biophys. J, 87,
1697-1704.
Walian, P., Cross, T. A., & Jap, B. K. (2004). Structural Genomics of Membrane Proteins.
Genome Biology, 5, 215.
Bertram, R., Asbury, T., Fabiola, F., Quine, J. R., Cross, T. A., & Chapman, M. S. (2003).
Atomic Refinement with Correlated Solid-State NMR Restraints. J. Magn. Reson, 163,
300-309.
Bingham, N. C., Smith, N. E. C., Cross, T. A., & Busath, D. D. (2003). Molecular Dynamics
Simulations of Trp Side-Chain Conformational Flexibility in the Gramicidin A Channel.
Biopolymers, 71, 593-600.
Tian, C., Gao, P. F., Pinto, L. H., Lamb, R. A., & Cross, T. A. (2003). Initial Structure and
Dynamic Characterization of the M2 Protein Transmembrane and Amphipathic Helices
in Lipid Bilayers. Protein Sci, 12, 2597-2605.
Cole, C. D., Frost, A. S., Thompson, N., Cotten, M., Cross, T. A., & Busath, D. D. (2002).
Non-contact dipole effects on channel permeation. VI. 5F- and 6F-Trp Gramicidin
Channel Currents. Biophys. J, 83, 1974-1986.
Fu, R., Tian, C., & Cross, T. A. (2002). NMR Spin Locking of Proton Magnetization under
Frequency Switched Lee-Goldburg (FSLG) Pulse Sequence". J. Magn. Reson, 154,
130-135.
Fu, R., Tian, C., Kim, H., Smith, S. A., & Cross, T. A. (2002). The Effect of Hartmann-Hahn
Mismatching on Polarization Inversion Spin Exchange at the magic Angle. J. Magn.
Reson, 159, 167-174.
Gan, Z., Gor'kov, P., Cross, T. A., Samosan, A., & Massiot, D. (2002). Seeking for Higher
Resolution and Sensitivity for NMR of Quadrupolar Nuclei at Ultra High Magnetic
Fields. J. Am. Chem. Soc, 124, 5634-5635.
Gowen, J. A., Markham, J. C., Morrison, S. E., Cross, T. A., Busath, D. D., Mapes, E. J., &
Schumaker, M. F. (2002). The Role of Trp Side Chains in Tuning Single Proton
Conduction Through Gramicidin Channels. Biophys. J, 83, 880-898.
Page 15
Vita for Timothy A Cross
Grage, S. L., Wang, J., Cross, T. A., & Ulrich, A. S. (2002). Structure Analysis of 19F-Labeled
Tryptophan side chains in Gramicidin A by solid-state 19F NMR of Oriented Samples.
Biophys. J, 83, 3336-3350.
Kim, S., & Cross, T. A. (2002). Uniformity, Ideality and Hydrogen Bonds in Transmembrane
-Helices. Biophys. J, 83, 2084-2095.
Nishimura, K., Kim, S., Zhang, L., & Cross, T. A. (2002). The Closed State of a H+ Channel
Helical Bundle: Combining Precise orientational and Distance Restraints from Solid State
NMR. Biochemistry, 41, 13170-13177.
Tian, C., Tobler, K., Pinto, L. H., Lamb, R., & Cross, T. A. (2002). Expression and Initial
Structural Insights from Solid State NMR of the M2 Proton Channel from influenza A
Virus. Biochemistry, 41, 11294-11300.
Anderson, D. G., Shirts, R. A., Cross, T. A., & Busath, D. D. (2001). Non-contact dipole effects
on channel permeation. V. Computed potentials for fluorinated gramicidin. Biophys. J,
81, 1255-1264.
Denny, J. K., Wang, J., Cross, T. A., & Quine, J. R. (2001). PISEMA Powder Patterns and PISA
Wheels. J. Magn. Reson, 152, 217-226.
Kim, S., Quine, J. R., & Cross, T. A. (2001). Complete Cross-Validation and R-Factor
Calculation of Solid-State NMR Derived Structures. J. Am. Chem. Soc, 123, 7292-7298.
Markham, J. C., Gowen, J. A., Cross, T. A., & Busath, D. D. (2001). Comparison of Gramicidin
A and Gramicidin M Channel Conductance Dispersities. Biochim. Biophys. Acta, 1513,
185-192.
Nishimura, K., Fu, R., & Cross, T. A. (2001). The Effect of RF Inhomogeneity on Heteronuclear
Dipolar Recoupling Solid State NMR: Practical Performance of SFAM and REDOR. J.
Magn. Reson, 152, 227-233.
Thompson, N., Thompson, G., Cole, C. C., Cotten, M., Cross, T. A., & Busath, D. D. (2001).
Non-contact dipole effects on channel permeation. IV. Kinetic model of 5F-Trp13
gramicidin A currents. Biophys. J, 81, 1245-1254.
Wang, J., Kim, S., Kovacs, F., & Cross, T. A. (2001). Structure of the Transmembrane Region of
the M2 Protein H+ Channel. Protein Sci, 10, 2241-2250.
Bertram, R., Quine, J. R., Chapman, M., & Cross, T. A. (2000). Atomic Refinement Using
Orientational Restraints from Solid-State NMR. J. Magn. Reson, 147, 9-16.
Page 16
Vita for Timothy A Cross
Byström, T., Strandberg, E., Kovacs, F. A., Cross, T. A., & Lindblom, G. (2000). Interaction of
Pgs Peptide E with PC Lipids of Different Chain Lengths. Biochim. Biophys. Acta, 1509,
335-345.
Cross, T. A., & Quine, J. R. (2000). Protein Structure in Anisotropic Environments:
Development of Orientational Constraints. Concepts in NMR, 12, 55-70.
Fu, R., Cotten, M., & Cross, T. A. (2000). Inter- and Intramolecular Distance Measurements by
Solid State Magic Angle Spinning NMR: Determination of Gramicidin A Channel Dimer
Structure in Hydrated Phospholipid Bilayers. " J. Biomol. NMR, 16, 261-268.
Kovacs, F. A., Denny, J. K., Song, Z., Quine, J. R., & Cross, T. A. (2000). Helix Tilt of the M2
Transmembrane Protein: An Intrinsic Property of the Protein". J. Mol. Biol, 295,
117-125.
Quine, J. R., & Cross, T. A. (2000). Protein Structure in Anisotropic Environments: Unique
Structural Fold from Orientational Constraints. Concepts in NMR, 12, 71-82.
Soghomonian, V., Sabo, M., Powell, A., Murphy, P., Rosanske, R., Cross, T. A., &
Schneider-Muntau, H. J. (2000). Identification and Minimization of Sources of Temporal
Instabilities in High Field (>23 Tesla) Resistive Magnets. Rev. Sci. Instrum, 71,
2882-2889.
Song, Z., Kovacs, F. A., Wang, J., Denny, J., Shekar, S. C., Quine, J. R., & Cross, T. A. (2000).
Transmembrane Domain of M2 Protein from Influenza A Virion as Studied by PISEMA
in Solid-State 15N NMR. Biophys. J, 79, 767-775.
Wang, J., Denny, J. K., Tian, C., Kovacs, F. A., Song, Z., Fu, R., Quine, J. R., & Cross, T. A.
(2000). Imaging Membrane Protein Helical Wheels". J. Magn. Reson, 144, 162-167.
Kovacs, F., Quine, J., & Cross, T. A. (1999). Validation of the Single-Stranded Channel
Conformation of Gramicidin A by Solid-State NMR. Proc. Natl. Acad. Sci. U.S.A, 96,
7910-7915.
Refereed Book Chapters
Cross, T. A. (in press). The M2 Proton Channel from Influenza A: An Example of Structural
Sensitivity to Environment. In Encyclopedia of Biophysics. Springer.
Das, N., Murray, D. T., Miao, Y., & Cross, T. A. (2014). "Helical Membrane Protein Structure:
Strategy for Success" in . Ed. In Frances Separovic, & Akira Naito (Eds.), Advances in
Biological Solid-State NMR: Proteins and Membrane Active Peptides. Royal Society of
Chemistry, Cambridge, UK.
Page 17
Vita for Timothy A Cross
Cross, T. A. (2013). Cross, T.A. () "M2 Proton Channel from Influenza A: An Example of
Structural Sensitivity to Environment". In Biophys. Encyclo (pp. 1321-1327). Springer.
Cross, T. A. (2010). The Origins of Membrane Proteins Structural Characterization in Lipid
Bilayers. In Harris, R.K., & Wasylishen, R.E. (Eds.), Encyclopedia Magn. Reson. John
Wiley, Chichester.
Fu, R., Brey, W. W., & Cross, T. A. (2009). Aligned Membrane Proteins: Structural Studies. In
Harris, R.K., & Wasylishen, R.E. (Eds.), Encyclopedia Magn. Reson. John Wiley,
Chichester.
Hu, J., Chekmenev, E., & Cross, T. A. (2006). Anisotropic Chemical Shift Perturbation by Ions
in Conducting Channels in Modern Magnetic Resonance. In Asakura, T., Saito, H., &
Ando, I. (Eds.), Part 1: Applications in Chemistry, Biological and Marine Sciences.
Springer.
Refereed Proceedings
Witter, R., Fu, R., Li, C., Cross, T. A., Sternberg, U., & Ulrich, A. S. (2010). Solid-state
15N-NMR Investigations on the pH Dependent Conformation of Trp-41 of the M2
Proton Channel of Influenza A Virus. In Anninos, P., Rossi, M., Pham, T.D., Falugi, C.,
Bussing, A., & Koukkou, M (Eds.), Unspecified conference (pp. 277-283). The World
Scientific and Engineering Academy and Society.
Presentations
Invited Keynote and Plenary Presentations at Conferences
Cross, T. A. (presented 2010, December). Sorting Structural Reality from the Artifacts: In
Search of Membrane Protein Functional Understanding. Plenary presentation at
Pacifichem, Honolulu, HI. (International)
Cross, T. A. (presented 2010, August). Sorting Structural Reality from the Artifacts: In Search of
Membrane Protein Functional Understanding. Not Available presentation at
International Conference on Magnetic Resonance in Biological Systems, Cains,
Australia. (International)
Cross, T. A. (presented 2008, October). Protein Drug Targets and Prospects for Drug-Screening
using Solid State NMR. Not Available presentation at Southeast Magnetic Resonance
Conference, Tallahassee, FL. (Regional)
Page 18
Vita for Timothy A Cross
Cross, T. A. (presented 2008, February). High Field NMR – Advantages and Challenges. Not
Available presentation at Workshop for European NMR Research Infrastructure,
Florence, Italy. (International)
Cross, T. A. (presented 2005, October). Conformational Plasticity and Functional
Understanding in M2 Protein – A Beginning. Not Available presentation at Viral Ion
Channels, Gargano, Italy. (International)
Cross, T. A. (presented 2005, January). Membrane Protein Structural Genomics. Not Available
presentation at 21st International Conference on Magnetic Resonance in Biological
Systems, Hyderabad, India. (International)
Cross, T. A. (presented 2001, May). From Topology to Cross-Validation of Macromolecular
Structures by Solid-State NMR. Not Available presentation at Annual Meeting of the
Polymer Society, Polymer Society, Japan, Tokyo. (International)
Cross, T. A. (presented 1998, August). Field NMR: A New Millenium Resource. Not Available
presentation at XVIIIth International Conference on Magnetic Resonance in Biological
Systems, Tokyo, Japan. (International)
Cross, T. A. (presented 1998, January). High Field NMR: A New Millenium Resource. Not
Available presentation at National High Magnetic Field Laboratory, Washington, DC.
(National)
Cross, T. A. (presented 1996, November). High Resolution Structure in Anisotropic
Environments by Solid State NMR. Not Available presentation at National (Japan) NMR
Meeting, Kyoto, Japan. (International)
Cross, T. A. (presented 1994, November). Structure and Dynamics of Biomolecules with Solid
State NMR in the National High Magnetic Field Laboratory. Not Available presentation
at NMR Program of the Japan Polymer Society, Japan Polymer Society, Tokyo, Japan.
(International)
Invited Presentations at Conferences
Cross, T. A. (presented 2011, January). Opportunities, Challenges and Urgency for the
Characterization of Membrane Protein Drug Targets. Presentation at From Molecules to
Medicines, Florida State University. (State)
Cross, T. A. (presented 2010, October). The Native M2 Protein Structure from Influenza A.
Presentation at Southeast Magnetic Resonance Conference, Gainesville, FL. (Regional)
Page 19
Vita for Timothy A Cross
Cross, T. A. (presented 2010, July). Sorting Structural Reality from the Artifacts: In Search of
Membrane Protein Functional Understanding. Presentation at International Society for
Magnetic Resonance, Florence, Italy. (International)
Cross, T. A. (presented 2010, May). Sorting Structural Reality from the Artifacts: In Search of
Membrane Protein Functional Understanding. Presentation at Florida Annual Meeting &
Exposition, Tampa, FL. (Regional)
Cross, T. A. (presented 2010, May). Sorting Structural Reality from the Artifacts: In Search of
Membrane Protein Functional Understanding. Presentation at 93rd Canadian Chemistry
Conference and Exhibition, Toronto Canada. (International)
Cross, T. A. (presented 2010, January). From PISA Wheels to High Resolution Membrane
Protein Structure. Presentation at Biological Solid State NMR Winter School, Stowe VT.
(National)
Cross, T. A. (presented 2010, January). Protein: Epression, Purification, Reconstitution, and
Sample Preparation. Presentation at Biological Solid State NMR Winter School, Stowe,
VT. (National)
Cross, T. A. (presented 2010, January). Sorting Structural Reality from Among the Artifacts: The
M2 Proton Channel. Presentation at Biological Solid State NMR Winter School, Stowe,
VT. (National)
Cross, T. A. (presented 2009, November). Sorting Structural Reality from the Artifacts: In
Search of Membrane Protein Functional Understanding. Presentation at Georgia-Tech
Biotech Symposium, Georgia Tech University, Atlanta GA. (Regional)
Cross, T. A. (presented 2009, July). Sorting Structural Reality from the Artifacts. Presentation at
Rocky Mountain Conference, Snowmass, Colorado. (International)
Cross, T. A. (presented 2009, February). Solid State NMR : A Novel Approach for Membrane
Protein Drug Screening. Poster presentation at Keystone Symposium: Frontiers of NMR
in Biology, Santa Fe, NM. (National)
Cross, T. A. (presented 2009, January). Mtb Membrane Proteins: A Potentially Novel Approach
for Drug Screening. Poster presentation at Keystone Symposium: Tuberculosis: Biology,
Pathology and Therapy, Keystone. (National)
Cross, T. A. (presented 2008, August). Membrane Protein Drug Targets and Prospects for
Drug-Screening using Solid-State NMR. Presentation at American Chemical Society
Meeting, American Chemical Society, Washington DC. (International)
Cross, T. A. (presented 2008, March). High Field NMR – Advantages and Challenges.
Presentation at Pioneering High Magnetic Fields, Tallahassee, Florida. (National)
Page 20
Vita for Timothy A Cross
Cross, T. A. (presented 2008, March). NMR User Facility at the National High Magnetic Field
Laboratory in Tallahassee, FL. Poster presentation at 49th ENC Conference, ENC,
Pacific Grove, CA. (International)
Cross, T. A. (presented 2008, February). Unique Insights into Membrane Protein Biophysics
through Structural Genomics. Presentation at 52nd Annual Biophysics Society Meeting,
Biophysics Society, Long Beach, California. (International)
Cross, T. A. (presented 2008, January). From PISA Wheels to High Resolution Membrane
Protein Structure. Presentation at Winter School for Biological Solid State NMR, Stowe,
Vermont. (National)
Cross, T. A. (presented 2008, January). Membrane Proteins from molecular Biology to Sample
Preparation to RF Engineering. Presentation at Winter School for Biological Solid State
NMR, Stowe, Vermont. (National)
Cross, T. A. (presented 2006, August). Advances in Solid State NMR of Membrane Proteins.
Presentation at International Conference on Magnetic Resonance in Biological Systems,
Gottingen. (International)
Cross, T. A. (presented 2006, July). 17O NMR Spectroscopy of Biological Systems at High Field.
Presentation at Rocky Mountain Conference, Breckenridge, CO. (International)
Cross, T. A. (presented 2006, July). Membrane Protein Spectroscopy at High Fields.
Presentation at – Experimental NMR Conference, Asilomar, CA. (National)
Cross, T. A. (presented 2006, April). NMR User Facility at the National High Magnetic Field
Laboratory in Tallahassee FL. Poster presentation at ENC Conference, ENC, Asilomar,
CA. (International)
Cross, T. A. (presented 2006, February). 17ONMR Analysis of the Gramicidin Channel.
Presentation at Gordon Research Conf.: Protons and Membrane Reactions, Ventura, CA.
(International)
Cross, T. A. (presented 2005, June). Structure, Dynamics and Function through Solid State NMR
of Membrane Proteins. Presentation at Gordon Research Conference: Magnetic
Resonance, Conneticut College. (National)
Cross, T. A. (presented 2005, February). Electrostatics in Membrane Bound Ion Channels
Characterized by Solid State NMR Spectroscopy. Presentation at National Society of
Black Physicists & National Society of Hispanic Physicists, Orlando, FL. (National)
Cross, T. A. (presented 2004, October). Solid State NMR of a H+ Channel: from Structure to
Function. Presentation at Center for Membrane Proteomics Summerschool, Frankfurt,
Germany. (International)
Page 21
Vita for Timothy A Cross
Cross, T. A. (presented 2004, September). Membrane Protein Expression, Sample Preparation
and Initial NMR Spectroscopy. Presentation at Structural Proteomics of Integral
Membrane Proteins, Marburg, Germany. (International)
Cross, T. A. (presented 2004, August). Challenges in the Solid State NMR of Membrane
Proteins. Presentation at Rocky Mountain Conference, Denver, CO. (International)
Cross, T. A. (presented 2004, April). The M2 Proton Channel from Influenza A Virus Structural
and Functional Studies by Solid-State NMR. Presentation at The 1st Pacific-Rim
International Conference on Protein Structure, Yokohama, Japan. (International)
Cross, T. A. (presented 2004, March). Ion Interactions with the Gramicidin Channel and Proton
Interactions with the M2 Channel. Presentation at American Physical Society Annual
Meeting, American Physical Society, Montreal, Canada. (International)
Cross, T. A. (presented 2004, January). NMR Studies of the M2 Protein Channel from Influenza
A Virus. Presentation at Membranes: A Challenge for Protein Magnetic Resonance,
Tallahassee, FL. (National)
Cross, T. A. (presented 2003, November). NMR Studies of M2 Protein and M2-TMP.
Presentation at M2 Protein Workshop, – Evanston, Illinois. (National)
Cross, T. A. (presented 2003, October). Crystal-Ball Gazing: Membrane Proteins at 900 MHz
and Above. Presentation at SouthEast Magnetic Resonance Conference, Tallahassee, FL.
(Regional)
Cross, T. A. (presented 2003, June). Aligned Lipid Matrices for Structural Characterization of
Membrane Proteins. Presentation at 16th International Meeting on NMR Spectroscopy,
Cambridge, England. (International)
Cross, T. A. (presented 2003, February). Structural Features and Function of the M2 Proton
Channel from Influenza A. Presentation at Joint Keystone meeting – Membrane Protein:
Structure and Mechanism; Frontiers of NMR in Molecular Biology VIII, Taos.
(International)
Cross, T. A. (presented 2002, October). Integral Membrane Protein Structural Genomics:
Mycobacterium tuberculosis. Presentation at ISGO International Conference on
Structural Genomics, Berlin Germany. (International)
Cross, T. A. (presented 2002, August). Advances in PISEMA Spectroscopy of Membrane
Proteins. Presentation at The 20th International Conference on Magnetic Resonance in
Biological Systems, Toronto Canada. (International)
Page 22
Vita for Timothy A Cross
Cross, T. A. (presented 2002, April). NMR Spectroscopy and Imaging Facility, National High
Magnetic Field Laboratory. Poster presentation at Annual Experimental NMR
Conference, Asilomar, CA. (National)
Cross, T. A. (presented 2002, February). Initial Structure of the M2 Proton Channel from
Influenza A Virus by Solid State NMR. Presentation at The 46th Annual Meeting of the
Biophysical Society, Biophysical Society, San Francisco CA. (International)
Cross, T. A. (presented 2001, September). High Performance High Field NMR in Resistive
Magnets. Presentation at 2nd Annual Meeting of the high Field Infrastructure
Cooperative Network, Nijmegen, The Netherlands. (International)
Cross, T. A. (presented 2001, September). PISA Wheels: Solid State NMR Topology Elucidation
of Membrane Protein Structure. Presentation at The 1st International Meeting on Proton
Channels, Villars, Switzerland. (International)
Cross, T. A. (presented 2001, September). PISA Wheels: Solid State NMR Topology Elucidation
of Membrane Proteins. Presentation at The 2nd Alpine Conference on Solid State NMR,
Chamonix, France. (International)
Cross, T. A. (presented 2001, August). From Topology to Refinement and Cross-Validation of
Membrane Bound Macromolecules by Solid-State NMR. Presentation at Rocky Mountain
Conference on Analytical Chemistry, Denver, CO. (International)
Cross, T. A. (presented 2001, August). Towards a high Resolution Structure of the M2 Proton
Channel in Influenza A Virus Using Solid-State NMR. Presentation at International
Society of Magnetic Resonance, International Society of Magnetic Resonance, Rhodes,
Greece. (International)
Cross, T. A. (presented 2001, May). Molecular Interactions and Structural Refinement in a
Membrane Environment. Presentation at Computational Aspects – Biomolecular NMR,
Ciocco, Italy. (International)
Cross, T. A. (presented 2000, December). Helical Wheels Directly Observed in
MembrneProteins by Solid State NMR. Presentation at Pacifichem '00 International
Chemical Congress, Honolulu, HI. (International)
Cross, T. A. (presented 2000, November). Solid-State NMR: A Tool for High Resolution
Macromolecular Structure Determination in a Bilayer Environment. Presentation at
Conference on the Frontiers in Structural Biology of Membrane Proteins, Galveston,
Texas. (International)
Cross, T. A. (presented 2000, October). From Topology to High Resolution Membrane Protein
Structures. Presentation at University of Leiden Workshop on the Future of Solid State
NMR in Biology, University of Leiden, Leiden, The Netherlands. (International)
Page 23
Vita for Timothy A Cross
Cross, T. A. (presented 2000, August). Imaging membrane Protein Helical Wheels. Presentation
at International Conference on Magnetic Resonance in Biological Systems, Florence,
Italy. (International)
Cross, T. A. (presented 2000, August). NMR Spectroscopy at High Fields: An NMR
Collaboratorium. Presentation at 2nd Annual EMSL Workshop on Structural Genomics
held at the Pacific Northwest National Laboratory, Pacific Northwest National
Laboratory, Richland WA. (International)
Cross, T. A. (presented 2000, April). Imaging membrane Protein Helical Wheels. Presentation at
41st Experimental NMR Conference, Asilomar, CA. (International)
Cross, T. A. (presented 2000, March). NMR Spectroscopy and Imaging User Facility, National
High Magnetic Field Laboratory. Poster presentation at Experimental NMR Conference,
Asilomar, CA. (National)
Cross, T. A. (presented 1999, September). Imaging Protein Helical Wheels. Presentation at
Workshop on Membrane Protein Structure Determination, Lake Tegernsee, Bavaria.
(International)
Cross, T. A. (presented 1999, August). Ion Conductance in a Model Channel: How Specificity
and Conductance Efficiency are Achieved. Presentation at 54th Annual Calorimetry
Conference, Tallahassee, FL. (National)
Cross, T. A. (presented 1999, May). Channel Structure in Lamellar Phase Lipids: Peptides to
Proteins. Presentation at Florida, American Chemical Society Meeting, American
Chemical Society, Orlando FL. (State)
Cross, T. A. (presented 1999, May). Orientational Constraints from Solid State NMR for High
Resolution Structural Characterization. Presentation at Annual Meeting of the American
Crystallographic Association, American Crystallographic Association, Buffalo NY.
(International)
Cross, T. A. (presented 1999, March). NMR Applications at Very High Fields. Poster
presentation at Experimental NMR Conference, Orlando, FL. (National)
Cross, T. A. (presented 1999, February). Channel Structure in Lamellar Phase Lipids: Peptides
to Proteins. Presentation at Industrial Analytical Directors Meeting, National High
Magnetic Field Laboratory. (National)
Cross, T. A. (presented 1999, January). Channel Structure in Lamellar Phase Lipids: Peptides to
Proteins. Presentation at Keystone Symposium on 'Fronteirs of NMR in Molecular
Biology VI, Breckenridge, CO. (International)
Cross, T. A. (presented 1998, November). Correlations of Structure, Dynamics and Function in
the Gramicidin Channel by Solid State NMR: I. Presentation at Norvalis Foundation
Page 24
Vita for Timothy A Cross
Symposium 225: Gramicidin and Related ion channel-forming peptides, Norvalis
Foundation, London England. (International)
Cross, T. A. (presented 1998, November). Correlations of Structure, Dynamics and Function in
the Gramicidin Channel by Solid State NMR: II. Presentation at Norvalis Foundation
Symposium 225: Gramicidin and Related ion channel-forming peptides, Norvalis
Foundation, London England. (International)
Cross, T. A. (presented 1998, August). Orientational Constraints: Their Precision, Accuracy and
Efficient Utilization in Structural Characterization of Silk Fibroin. Presentation at
Proceedings of the International Symposium on Silk and NMR, Tokyo, Japan.
(International)
Cross, T. A. (presented 1998, June). High Resolution Structure and Dynamics of
Membrane-Bound Polypeptides. Presentation at Annual meeting of the Canadian
Federation of Biological Sciences, Canadian Federation of Biological Sciences,
Edmonton, Canada. (International)
Cross, T. A. (presented 1998, February). M2 Protein from Influenza Virus: A Preliminary View
from Soli-State NMR. Presentation at Biophysics Society Meeting, Biophysics Society,
Kansas City KS. (International)
Cross, T. A. (presented 1998, January). High Resolution Macromolecular Structure and
Dynamics by Solid State NMR. Poster presentation at High Field NMR: A New
Millennium Resource Conference, Washington DC. (National)
Cross, T. A. (presented 1997, August). High Resolution Structure of a Lipid Bilayer-Bound
Polypeptide: Gramicidin A. Presentation at 13th Scandinavian Symposium on Surface
Chemistry, Umea, Sweden. (International)
Cross, T. A. (presented 1997, August). Macromolecular Structure from Solid-State NMR
Derived Orientational Constraints. Presentation at Membrane Workshop, Umea,
Sweden. (International)
Cross, T. A. (presented 1997, April). Solvent Mediated Conformational Interconversion: A
Catalytic Role for Protic Solvents. Presentation at Structural Biology Workshop, Oxford,
England. (International)
Cross, T. A. (presented 1997, March). Deuterium Spectroscopy at 20 and 24.6T. Presentation at
Experimental NMR Conference, Orlando, FL. (International)
Cross, T. A. (presented 1997, February). Tryptophan, the Unique Amino Acid of Membrane
Proteins: A Perspective from Gramicidin and Solid State NMR. Presentation at Winter
Gordon Conference on Proteins and Membranes, Ventura, CA. (International)
Page 25
Vita for Timothy A Cross
Cross, T. A. (presented 1996, October). Solid-State NMR Derived Structure: Membrane Bound
Polypeptides to Proteins. Presentation at SEMRC, Tuscaloosa, AL. (International)
Cross, T. A. (presented 1996, August). Trytophan, the Unique Amino Acid of Membrane
Proteins: A Perspective from Gramicidin and Solid State NMR. Presentation at XVIIth
International Conference on Magnetic Resonance in Biological Systems, Keystone, CO.
(International)
Cross, T. A. (presented 1995, December). High Resolution Dynamics and Structure
Characterization by Solid State NMR: From Biopolymers to Synthetic Polymers.
Presentation at Pacifichem '95 International Chemical Congress, Honolulu, HI.
(International)
Cross, T. A. (presented 1995, November). The Atomic Resolution Structural Characterization of
a Bilayer Solubilized Polypeptide by Solid State NMR Spectroscopy. Presentation at
Workshop on - The Techniques of Today and Tomorrow for the Study of Molecular
Structure, Function and Dynamics, Lund, Sweden. (International)
Cross, T. A. (presented 1995, September). Structural Characterization from Solid State
NMR-Derived Orientational Constraints: The Gramicidin Channel in a Lipid Bilayer.
Presentation at Fogarty International Center Conference on Membrane Ion Channels:
Structure and Function, Washington, DC. (International)
Cross, T. A. (presented 1995, May). Molecular Dynamics by Solid State NMR in a
Membrane-Bound Polypeptide. Presentation at Florida Section of the American Chemical
Society, American Chemical Society, Tampa FL. (State)
Cross, T. A. (presented 1994, August). High Resolution Structure and Dynamics at the
Protein/Lipid Interface: The Gramicidin Channel in Hydrated Lipid Bilayers.
Presentation at XVIth International Conference on Magnetic Resonance in Biological
Systems, Veldhoven, The Netherlands. (International)
Cross, T. A. (presented 1994, August). Structural Characterization from Solid State
NMR-Derived Orientational Constraints: Extending a Biopolymer Technique to Synthetic
Polymers. Presentation at National ACS Meeting: International Symposium on Polymer
Spectroscopy, American Chemical Society, Washington DC. (International)
Cross, T. A. (presented 1994, June). High Resolution Dynamics at the Protein/Lipid Interface:
The Gramicidin Channel in Hydrated Lipid Bilayers. Presentation at Blue Hen NMR
Conference, Wilmington, NC. (National)
Cross, T. A. (presented 1994, May). High Resolution Three Dimensional Protein Structure from
Solid State NMR Spectroscopy: The Gramicidin Channel. Presentation at GERM
Meeting, Strasbourg GERMANY. (International)
Page 26
Vita for Timothy A Cross
Cross, T. A. (presented 1994, March). High Resolution Polypeptide Structure in Anisotropic
Environments: The gramicidin channel in lipid bilayers. Presentation at Los Alamos
Workshop, National High Magnetic Field Laboratory, Santa Fe, NM. (International)
Cross, T. A. (presented 1994, March). Lipid-Peptide Interface: A View from the Peptide.
Presentation at Biophysical Society Annual Meeting, Biophysical Society, New Orleans
LA. (International)
Cross, T. A. (presented 1994, January). Ultra-High Resolution Structure from Orientational
Constraints in Anisotropic Environments: The gramicidin channel in lipid bilayers.
Presentation at Experimental NMR Conference, Asilomar, CA. (International)
Cross, T. A. (presented 1993, October). Ultra-High Resolution Structure from Orientational
Constraints in Anisotropic Environments. Presentation at Southeastern NMR Conference,
Gainesville, FL. (Regional)
Cross, T. A. (presented 1993). Gramicidin A Structure Determination in Lipid Bilayers and
Model Bilayer Environments by Solution and Solid State NMR. Presentation at Florida
Section Annual Meeting of the Americal Chemical Society, Americal Chemical Society,
Orlando FL. (State)
Cross, T. A. (presented 1993). High Resolution Structure, Dynamics and Function of the
Gramicidin A Channel. Presentation at Keystone Symposia on Molecular and Cell
Biology: Joint Session - Fronteirs of NMR in Molecular Biology III and Prospects and
Progress in Drug Design Based on Peptides and Proteins, Taos. (International)
Cross, T. A. (presented 1992). Membrane Bound Polypeptide Structure and Dynamics by Solid
State NMR. Presentation at 34th Rocky Mountain Conference on Magnetic Resonance,
Denver, CO. (International)
Cross, T. A. (presented 1992). National High Magnetic Field Laboratory: NMR Spectroscopy in
the Future. Presentation at Florida Section Annual Meeting of the Americal Chemical
Society, Americal Chemical Society, Cocoa Beach FL. (International)
Cross, T. A. (presented 1992). Structure and Dynamics of a Membrane Bound Polypeptide.
Presentation at Biophysical Society Annual Meeting, Biophysical Society, Houston TX.
(International)
Cross, T. A. (presented 1992). Structure and Dynamics of a Membrane Bound Polypeptide.
Presentation at XIth Meeting of the International Society for Magnetic Resonance,
International Society for Magnetic Resonance, Vancouver CANADA. (International)
Cross, T. A. (presented 1991, January). Development of the User's Program. Presentation at
Co-Organizer for the National High Magnetic Field Laboratory, National High Magnetic
Field Laboratory, Gainesville, FL. (National)
Page 27
Vita for Timothy A Cross
Cross, T. A. (presented 1991). Atomic Resolution of Protein and Polypeptide Structure by Solid
State NMR. Presentation at International Symposium on Biotechnology sponsored by the
Society of Fiber Science and Technology, Tokyo, Japan. (International)
Cross, T. A. (presented 1991). High Resolution NMR - Advances in Chemistry. Presentation at
Special Symposium on High Magnetic Field Research at the 28th Annual Technical
Meeting of the Society of Engineering Science, Society of Engineering Science,
Gainesville FL. (National)
Cross, T. A. (presented 1990, December). Structure and Dynamics of the Gramicidin Cation
Channel. Presentation at Southeast-Southwest Regional ACS Meeting, American
Chemical Society, New Orleans LA. (Regional)
Cross, T. A. (presented 1990). Polypeptide Structure and Dynamics by Solid State NMR.
Presentation at the Univ. of Florida Interdisciplinary Center for Biotechnology Research
Workshop on NMR and Structure of Biomolecules Gainesville Biotechnology
Conference, Univeristy of Florida, Gainesville FL. (Regional)
Cross, T. A. (presented 1989). Atomic Resolution Structure and Dynamics of the Gramicidin
Channel by Solid State NMR Spectroscopy. Poster presentation at Proteins Gordon
Conference, Ventura, CA. (International)
Cross, T. A. (presented 1989). Atomic Resolution Structure of the Gramicidin Channel by Solid
State NMR Spectroscopy. Poster presentation at Analytical Gordon Conference, Gordon
Conference. (National)
Cross, T. A. (presented 1989). Molecular Dynamics by Solid State NMR. Poster presentation at
Analytical Gordon Conference, Gordon Conference. (National)
Cross, T. A. (presented 1989). Polypeptide Structure and Dynamics by Solid State NMR.
Presentation at Conference on Molecular Approaches to the Elucidation of Biological
Functions by Stable Isotope Aided NMR Spectroscopy, Oiso, Japan. (International)
Cross, T. A. (presented 1989). Polypeptide Structure and Dynamics by Solid State NMR.
Presentation at Southeast Regional NMR Conference, Memphis TN. (Regional)
Cross, T. A. (presented 1988). 15N Solid State NMR of the Gramicidin A Cation Channel.
Presentation at 40th Southeast Regional ACS Meeting, American Chemical Society,
Atlanta, GA. (Regional)
Cross, T. A. (presented 1988). Dynamics of the Gramicidin A Transmembrane Channel by Solid
State 15N NMR. Presentation at Experimental NMR Conference, Rochester, N.Y.
(International)
Page 28
Vita for Timothy A Cross
Cross, T. A. (presented 1985). Dynamic and Structural Elucidation of Biomolecules by Solid
State NMR. Presentation at Second International Symposium on the Synthesis and
Application of Isotopically Labeled Compounds, Kansas City, MO. (International)
Refereed Presentations at Conferences
Das, N. (presented 2010, August). Regulation of M. tuberculosis Cell Division: Discovery of
Protein Complexes. Poster presentation at 24th Symposium of the Protein Society,
Protein Society, San Diego, CA. (International)
Jean-Francois, F. L. (presented 2010, August). Characterization of a Heterodimer Peptide within
the Membrane Using PISEMA. Poster presentation at 39th Southeast Magnetic
Resonance Conference, University of Florida, Gainesville, FL. (Regional)
Jean-Francois, F. L. (presented 2010, August). Peptide-Peptide Interaction within the Membrane
Using PISEMA Based Experiments. Poster presentation at 24th International Conference
on Magnetic Resonance in Biological Systems, Cairns, Australia. (International)
Jean-Francois, F. L. (presented 2010, April). Is MgtC, a Potential Drug Target in M.
tuberculosis, Inhibited by MgtR? Peptide Interaction Study Using PISEMA. Poster
presentation at 51st ENC Conference, ENC, Daytona, FL. (International)
Murray, D. (presented 2010, April). Novel Analysis of Kinked Helices from PISEMA Data.
Poster presentation at 51st ENC Conference, ENC, Daytona, FL. (International)
Ni, D. (presented 2010, April). LpqH is the Enzymatic Target for LspA, A Drug Target for M.
tuberculosis. Poster presentation at 51st ENC Conference, ENC, Daytona, FL.
(International)
Sharma, M. (presented 2010, April). High Resolution Backbone Structure of M2 Proton Channel
from Influenza A Virus by Solid State NMR. Poster presentation at 51st ENC Conference,
ENC, Daytona, FL. (International)
Murray, D. (presented 2010, February). Solid State NMR Observation of the Geometry of Kinked
Protein Helices. Poster presentation at 54th Annual Biophysical Society Meeting,
Biophysical Society, San Francisco, CA. (International)
Peterson, E. (presented 2010, February). Acid Activation, Proton Transport Rate Saturation and
pH Dependence of Amantadine Block for Influenza A M2 Proton Truncate (22-62).
Poster presentation at 54th Annual Biophysical Society Meeting, Biophysical Society,
San Francisco, CA. (International)
Page 29
Vita for Timothy A Cross
Ryser, T. J. (presented 2010, February). Functional Reconstitution of Influenza A M2 (22-62).
Poster presentation at 54th Annual Biophysical Society Meeting, Biophysical Society,
San Francisco, CA. (International)
Sharma, M. (presented 2010, February). Structural and Functional Studies of M2 Proton
Channel from Influenza A Virus. Poster presentation at 54th Annual Biophysical Society
Meeting, Biophysical Society, San Francisco, CA. (International)
Edison, A. S. (presented 2009, March). Chemistry and Biology at the National High Magnetic
Field Laboratory. Poster presentation at 50th ENC Conference, ENC, Pacific Grove, CA.
(International)
Murray, D. T. (presented 2009, March). Solid State NMR Studies of Structure-Activity
Relationships in Large Membrane Proteins. Poster presentation at 50th ENC Conference,
ENC, Pacific Grove, CA. (International)
Ni, D. (presented 2009, March). Purification, Refolding and Structural Investigations of the
Membrane Protein, Lipoprotein Signa Peptidase (LspA) by Solid State NMR. Poster
presentation at 50th ENC Conference, ENC, Pacific Grove, CA. (International)
Sharma, M. (presented 2009, March). M2 Proton Channel from Influenza A Virus Studied by
Solid State NMR Spectroscopy. Poster presentation at 50th ENC Conference, ENC,
Pacific Grove, CA. (International)
Truong, M. (presented 2009, March). Chemical Shift Anisotropy Tensor Measurements using
High Resolution Heteronuclear Correlation Spectroscopy in Solid State NMR. Poster
presentation at 50th ENC Conference, ENC, Pacific Grove, CA. (International)
Murray, D. T. (presented 2009, February). Solid State NMR of Membrane Proteins: Towards
complex structural and functional information for bacterial ABC class transporters.
Poster presentation at 53rd Annual Biophysical Society Meeting, Biophysical Society,
Boston, MA. (International)
Ni, D. (presented 2009, February). Making Membrane Protein LspA Samples and its uniformly
aligned full lengh investigated by Solid State NMR. Poster presentation at 53rd Annual
Biophysical Society Meeting, Biophysical Society, Boston, MA. (International)
Plocinski, P. (presented 2009, February). Initial Characterization of Rv0008c and Rv0011c, two
potential cell division regulatory proteins of Mycobacterium tuberculosis. Poster
presentation at Texas TB Meeting, Texas TB Education Center. (State)
Sharma, M. (presented 2009, February). Structural and Functional Studies of M2 Proton
Channel from Influenza A Virus. Poster presentation at 53rd Annual Biophysical Society
Meeting, Biophysical Society, Boston, MA. (International)
Page 30
Vita for Timothy A Cross
Truong, M. L. (presented 2009, February). Ion Interactions of Gramicidin A using
Multidimensional Proton Solid State NMR. Poster presentation at 53rd Annual
Biophysical Society Meeting, Biophysical Society, Boston, MA. (International)
Yi, M. (presented 2009, February). Conformational Heterogeneity of the M2 Proton Channel: A
Model for Channel Activation. Poster presentation at 53rd Annual Biophysical Society
Meeting, Biophysical Society, Boston, MA. (International)
Mananga, E. S. (presented 2008, October). Enhanced Sensitivity and Resolution for
Orientational Restraints from Lipid Bilayer Bound Gramicidin A. Poster presentation at
37th Southeast Magnetic Resonance Conference, Florida State University, Tallahassee,
FL. (Regional)
Murray, D. T. (presented 2008, October). Solid State NMR of Membrane Proteins: Towards
Complex Structure and Functional Information for Bacterial ABC Class Importers.
Poster presentation at 37th Southeast Magnetic Resonance Conference, Florida State
University, Tallahassee, FL. (Regional)
Qian, C. (presented 2008, October). Polarization Inversion Spin Exchange at the Magic Angle
(PISEMA). Poster presentation at 37th Southeast Magnetic Resonance Conference,
Florida State University, Tallahassee, FL. (Regional)
Chekmenev, E. Y. (presented 2008, March). Macroscopic Alignment and Leaflet Solvent
Accessibility of Nanopore-Confined Lipid Bilayer Arrays as a Function of Lipid
Composition. Poster presentation at 49th ENC Conference, ENC, Pacific Grove, CA.
(International)
Gor'kov, P. L. (presented 2008, March). Applications of Low-E coils to High Field SS NMR of
Proteins Aligned in Bicelles. Poster presentation at 49th ENC Conference, ENC, Pacific
Grove, CA. (International)
Sharma, M. (presented 2008, March). Solid State NMR Studies of Uniformly Aligned Full-length
Membrane Proteins. Poster presentation at 49th ENC Conference, ENC, Pacific Grove,
CA. (International)
Truong, M. L. (presented 2008, March). High Resolution Heteronuclear Correlation
Spectroscopy in Solid State NMR of Aligned Samples. Poster presentation at 49th ENC
Conference, ENC, Pacific Grove, CA. (International)
Jones, T. L. (presented 2008, February). Persistent Gramicidin a Channel Gating. Poster
presentation at Biophysical Society 52nd Annual Meeting, Biophysical Society, Long
Beach, CA. (International)
Page 31
Vita for Timothy A Cross
Moore, J. (presented 2008, February). Inducing Order in ChiZ, a Natively Disordered Membrane
Protein from Mycobacterium tuberculosis. Poster presentation at Biophysical Society
52nd Annual Meeting, Biophysical Society, Long Beach, CA. (International)
Nguyen, H. B. (presented 2008, February). Solution Structure of Integral Membrane Protein
from Mycobacterium tuberculosis: Insight into Rv0008c: An FtsZ Inhibitor and Its
Complex. Poster presentation at Biophysical Society 52nd Annual Meeting, Biophysical
Society, Long Beach, CA. (International)
Page, R. (presented 2008, February). A Diving into the Spectral Depths: Torsion Angle Mapping
as a Probe for Transmembrane Helix Uniformity. Poster presentation at Biophysical
Society 52nd Annual Meeting, Biophysical Society, Long Beach, CA. (International)
Sharma, M. (presented 2008, February). M2 Proton Channel from Influenza A Virus Studied by
Solution and Solid-State NMR Spectroscopy. Poster presentation at Biophysical Society
52nd Annual Meeting, Biophysical Society, Long Beach, CA. (International)
Yi, M. (presented 2008, February). Helix Kinking, Conformational Heterogeneity, and Blockage
of the M2 Proton Channel: Roles of Water Molecules and Amantadine Binding. Poster
presentation at Biophysical Society 52nd Annual Meeting, Biophysical Society, Long
Beach, CA. (International)
Nguyen, H. B. (presented 2007, April). Initial Characterization of Rv0008c, an Integral
Membrane Protein from Mycobacterium tuberculosis by Solution NMR Spectroscopy.
Poster presentation at ENC Conference, ENC, Daytona, FL. (International)
Page, R. C. (presented 2007, April). Transmembrane Helix Structure in Two Distinct Membrane
Mimetics: Applying Solution and Solid State NMR to Examine the Structure of KdpC.
Poster presentation at ENC Conference, ENC, Daytona, FL. (International)
Sharma, M. (presented 2007, April). Solution and Solid State NMR Studies of M2 Proton
Channel of Influenza A Virus. Poster presentation at ENC Conference, ENC, Daytona,
FL. (International)
Chase, R. A. (presented 2007, February). Characterization of Membrane Proteins from M.
tuberculosis Using Solution and Solid State NMR. Poster presentation at Biophysical
Society 51st Annual Meeting, Biophysical Society, Baltimore, MD. (International)
Nielson, F. (presented 2007, February). External His Mutations Affect Proton Conductance of
Influenza M2 Channels. Poster presentation at Biophysical Society 51st Annual Meeting,
Biophysical Society, Baltimore, MD. (International)
Page 32
Vita for Timothy A Cross
Yi, M. (presented 2007, February). Molecular Dynamics Study of Amantadine Inhibition of the
M2 Ion Channel of Influenza A in Phospholipid Bilayers. Poster presentation at
Biophysical Society 51st Annual Meeting, Biophysical Society, Baltimore, MD.
(International)
Li, C. (presented 2006, October). M2-TMD Conformational Plasticity and Function. Poster
presentation at SE Magnetic Resonance Conference, University of Florida, Gainesville,
FL. (Regional)
Qin, H. (presented 2006, October). Structural Genomics of Integral Membrane Proteins from
Mycobacterium tuberculosis. Poster presentation at 4th ISGO International Conference
on Structural Genomics, ISGO, Yokohama, Japan/Beijing, China. (International)
Nguyen, H. B. (presented 2006, August). Solution NMR of alpha-helical membrane proteins
Rv0008c and Rv1567c from Mycobacterium tuberculosis. Poster presentation at XXIInd
International Conference on Magnetic Resonance in Biological Systems, Göttingen,
Germany. (International)
Page, R. C. (presented 2006, August). Alpha-Helical Membrane Protein Structure by Solution
and Solid State NMR: Examining KdpC and Rv1861 from Mycobacterium tuberculosis.
Poster presentation at International Conference on Magnetic Resonance in Biological
System, Göttingen, Germany. (International)
Witter, R. (presented 2006, August). Structure Refinement of M2-TMD. Poster presentation at
ICMRBS Conference, Goettingen, Germany. (International)
Gor'kov, P. L. (presented 2006, July). Low-E Probes for High Frequency Biological SS NMR.
Poster presentation at Rocky Mountain Conference on Analytical Chemistry,
Breckenridge, CO. (International)
Chase, R. A. (presented 2006, April). Characterizing Membrane Proteins from M. Tuberculosis,
Calculating Residual Dipolar Couplings. Poster presentation at ENC Conference, ENC,
Asilomar, CA. (International)
Chekmenev, E. Y. (presented 2006, April). Flow-through Lipid Nanotube Arrays for
Macroscopic Alignment and Structure-function Studies of Membrane proteins by
Solid-state NMR Spectroscopy. Poster presentation at ENC Conference, ENC, Asilomar,
CA. (International)
Chekmenev, E. Y. (presented 2006, April). Towards 17O Solid State NMR Spectroscopy of
Ion-selective Channels at Ultra-high Magnetic Fields. Poster presentation at ENC
Conference, ENC, Asilomar, CA. (International)
Page 33
Vita for Timothy A Cross
Gor'kov, P. (presented 2006, April). Applications of Low-E Static Probes to High Frequency
Membrane Protein NMR. Poster presentation at ENC Conference, ENC, Asilomar, CA.
(International)
Hu, J. (presented 2006, April). Expression, Purification and Preliminary NMR Studies of the
Transmembrane Domain of CorA, a Magnesium Transporter from Mycobacterium
Tuberculosis. Poster presentation at ENC Conference, ENC, Asilomar, CA.
(International)
Li, C. (presented 2006, April). Two Molecular Mechanisms toward Influenza A Virus Resistant
to Antiviral Drug: Amantadine - a Solid State NMR Study. Poster presentation at ENC
Conference, ENC, Asilomar, CA. (International)
Nguyen, H. B. (presented 2006, April). Effect of Paramagnetic Relaxation on Integral
Membrane Proteins from Mycobacterium tuberculosis by Solution NMR Spectroscopy.
Poster presentation at ENC Conference, ENC, Asilomar, CA. (International)
Nozirov, F. (presented 2006, April). 19F Solid-state NMR Studies of the Transmembrane
Domain of the M2 protein. Poster presentation at ENC Conference, ENC, Asilomar, CA.
(International)
Page, R. C. (presented 2006, April). Comprehensive Evaluation of Solution Nuclear Magnetic
Resonance Spectroscopy Sample Preparation for Helical Integral Membrane Proteins.
Poster presentation at ENC Conference, ENC, Asilomar, CA. (International)
Sharma, M. (presented 2006, April). Progress in Solution NMR based Structural
Characterization of M2 Proton Channel from Influenza A Virus. Poster presentation at
ENC Conference, ENC, Asilomar, CA. (International)
Witter, R. (presented 2006, April). New Theoretical and Experimental Concepts of Solid State
19F-NMR for Biological Applications. Poster presentation at ENC Conference, ENC,
Asilomar, CA. (International)
Busath, D. (presented 2006, February). Conductance Properties of Influenza A Virus M2
Variants in Planar Lipid Bilayers. Poster presentation at Biophysical Society 50th
Annual Meeting, Biophysical Society, Salt Lake City, UT. (International)
Chekmenev, E. Y. (presented 2006, February). Gramicidin A Channels in Substrate-Supported
Lipid Nanotube Bilayers. Poster presentation at Biophysical Society 50th Annual
Meeting, Biophysical Society, Salt Lake City, UT. (International)
Vijayvergiya, V. (presented 2006, February). Proton Conductance of Influenza A Virus M2
Mutants and M2 TMP in Planar Lipid Bilayers. Poster presentation at Biophysical
Society 50th Annual Meeting, Biophysical Society, Salt Lake City, UT. (International)
Page 34
Vita for Timothy A Cross
Yi, M. (presented 2006, February). Calculation of pKa's for histidine at the center of the
influenza A M2 proton channel. Poster presentation at Biophysical Society 50th Annual
Meeting, Biophysical Society, Salt Lake City, UT. (International)
Achuthan, S. (presented 2005, April). PiPath: An Assignment Algorithm for Solid-State NMR
PISEMA Spectra. Poster presentation at Annual Experimental NMR Conference,
Providence, RI. (National)
Asbury, T. M. (presented 2005, April). Structures of the M2-TMP Proton Channel from
Influenza A Virus in the Presence of Amantadine. Poster presentation at Annual
Experimental NMR Conference, Providence, RI. (National)
Fu, R. (presented 2005, April). Use of Asymmetric Frequency Switched Lee Goldurg in
Polarization Inversion Spin Exchange at the Magic Angle. Poster presentation at Annual
Experimental NMR Conference, Providence, RI. (National)
Achuthan, S. (presented 2005, February). Analysis of Orientational Restraints from Solid State
NMR for Membrane Protein Structure Determination. Poster presentation at Annual
Biophysics Society Meeting, Biophysics Society, Long Beach, California. (International)
Moore, J. D. (presented 2005, February). Solution NMR in Various Condiionson Mycobacterium
tuberculosis Integral Membrane Proteins Rv2719c, Rv1761c and Rv1824 Expressed in E.
coli. Poster presentation at Annual Biophysics Society Meeting, Biophysics Society,
Long Beach, California. (International)
Nguyen, H. B. (presented 2005, February). Expression, Purification and Initial Characterization
of Several Integral Membrane Proteins from Mycobacterium tuberculosis. Poster
presentation at Annual Biophysics Society Meeting, Biophysics Society, Long Beach,
California. (International)
Page, R. C. (presented 2005, February). Characterizing alpha-Helical Integral Membrane
Proteins: Initial Results Torwards a Joint Solution and Solid State NMR Based Structure
Elucidation Scheme. Poster presentation at Annual Biophysics Society Meeting,
Biophysics Society, Long Beach, California. (International)
Pearson, J. K. (presented 2005, February). Ammonium Conductance Properties of Influenza A
M2 Channels in Lipid Bilayers: pH Dependence. Poster presentation at Annual
Biophysics Society Meeting, Biophysics Society, Long Beach, California. (International)
Sharma, M. (presented 2005, February). Expression, Purification and Initial Characterization of
the Integral Membrane Protein, Rv0150c from Mycobacterium tuberculosis by NMR
Spectroscopy. Poster presentation at Annual Biophysics Society Meeting, Biophysics
Society, Long Beach, California. (International)
Page 35
Vita for Timothy A Cross
Strongin, B. A. (presented 2005, February). Atomic Force Microscopy Imaging of
Antibody-Bound Influenza A M2 Protein. Poster presentation at Annual Biophysics
Society Meeting, Biophysics Society, Long Beach, California. (International)
Vijayvergiya, V. (presented 2005, February). Proton Conductance of 6F19 – Trp15,41 Influenza
A Protein in Planar Lipid Bilayers. Poster presentation at Annual Biophysics Society
Meeting, Biophysics Society, Long Beach, California. (International)
Vijayvergiya, V. (presented 2005, February). Proton Conductance of the Influenza A M2
Transmembrane Peptide in Lipid Bilayers. Poster presentation at Annual Biophysics
Society Meeting, Biophysics Society, Long Beach, California. (International)
Asbury, T. (presented 2004, October). PIPATH: An Assignment Algorithm for Solid-State NMR
PISEMA Data. Poster presentation at 15th Triennial Conference for the International
Society for Magnetic Resonance, International Society for Magnetic Resonance, Ponte
Vedra Beach, Florida. (International)
Chekmenev, E. (presented 2004, October). Ion Binding Study by 17O MAS NMR Sppectroscopy
at High Fieeld and by Ab Initio Calculations in Model Peptide Systems. Poster
presentation at 15th Triennial Conference for the International Society for Magnetic
Resonance, International Society for Magnetic Resonance, Ponte Vedra Beach, Florida.
(International)
Hu, J. (presented 2004, October). New Prospects, New Challenges with Membrane Protein
Structure, Dynamics and Function. Presentation at 15th International Society for
Magnetic Resonance Meeting, iety for Magnetic Resonance, Ponte Vedra Beach, FL.
(International)
Hu, J. (presented 2004, October). Structure Determination of the M2-TMP Proton Channel from
Influenza A Virus in the Presence of Amantaadine using Orientational Restraints. Poster
presentation at 15th Triennial Conference for the International Society for Magnetic
Resonance, International Society for Magnetic Resonance, Ponte Vedra Beach, Florida.
(International)
Moore, J. A. (presented 2004, October). Initial Characterization of Mycobacterium tubeculoosis
integral Membrane Proteins: Rv2719c, Rv1761c and Rv0008c Expressed in E. coli.
Poster presentation at 15th Triennial Conference for the International Society for
Magnetic Resonance, International Society for Magnetic Resonance, Ponte Vedra Beach,
Florida. (International)
Nguyen, H. (presented 2004, October). Expression, Purification and Initial Characterization of
Two Membrane Proteins: Rv0476c and Rv1824 from Mycobacterium tubeculosis. Poster
presentation at 15th Triennial Conference for the International Society for Magnetic
Resonance, International Society for Magnetic Resonance, Ponte Vedra Beach, Florida.
(International)
Page 36
Vita for Timothy A Cross
Page, R. C. (presented 2004, October). Structural Characterization of the Integral Membrane
Protein Rv2433c from Mmycobacterium tuberculosis by solution and solid-state NMR
Spectroscopy. Poster presentation at 15th Triennial Conference for the International
Society for Magnetic Resonance, International Society for Magnetic Resonance, Ponte
Vedra Beach, Florida. (International)
Saha, S. (presented 2004, October). Faraday Shielding of Solid-State NMR Samples. Poster
presentation at 15th Triennial Conference for the International Society for Magnetic
Resonance, International Society for Magnetic Resonance, Ponte Vedra Beach, Florida.
(International)
Chekmenev, E. Y. (presented 2004, April). Mycobacterium tuberculosis: Solid State NMR study
of Rv2433c protein. Poster presentation at Annual Experimental NMR Conference,
Asilomar, CA. (National)
Fu, R. (presented 2004, April). Towards Quantitative Measurements in Solid-State CP/MAS
NMR. Poster presentation at Annual Experimental NMR Conference, Asilomar, CA.
(National)
Hu, J. (presented 2004, April). Structures of the M2-TMP Proton Channel from Influenza A
Virus in the Presence of Amantadine. Poster presentation at Annual Experimental NMR
Conference, Asilomar, CA. (National)
Li, C. (presented 2004, April). Analysis of RF Heating and Sample Stability in Aliigned Static
Solid-State NMR Spectroscopy. Poster presentation at Annual Experimental NMR
Conference, Asilomar, CA. (National)
Mo, Y. (presented 2004, April). Membrane Protein Sample Preparation for Anisotropic Solid
State NMR Experiments. Poster presentation at Annual Experimental NMR Conference,
Asilomar, CA. (National)
Wiener, M. (presented 2004, March). Membrane protein Structural Genomics: Multiple
approaches for sample preparation. Poster presentation at NIGMS 2004 PSI Protein
Production and Crystallization Workshop, NIGMS, Bethesda, MD. (National)
Xiong, Y. (presented 2004, March). ESI FT-ICR Mass Spectrometry Analysis of Mycobacterium
tuberculosis H37Rv Periferal Membrane Proteins. Poster presentation at Annual meeting
of the American Society of Mass Spectroscopists, American Society of Mass
Spectroscopists. (National)
Achuthan, S. (presented 2004, February). Structure Determination of the Amantadine-Blocked
M2 Transmembrane Segment Using Orientational Restraints from Solid-State NMR.
Poster presentation at Annual Biophysics Society Meeting, Biophysics Society,
Baltimore, Maryland. (International)
Page 37
Vita for Timothy A Cross
Hu, J. (presented 2004, February). Histidine Protonation in the Transmembrane Segment of the
M2 Proton Channel from Influenza A Virus. Poster presentation at Annual Biophysics
Society Meeting, Biophysics Society, Baltimore, Maryland. (International)
Moore, J. (presented 2004, February). Expression, Purification and Initial Characterization of
Mycobacterium tuberculosis Integral Membrane Proteins. Poster presentation at Annual
Biophysics Society Meeting, Biophysics Society, Baltimore, Maryland. (International)
Nguyen, H. (presented 2004, February). Semisynthesis and Initial Characterization of the M2
Proton Channel from Influenza A Virus. Poster presentation at Annual Biophysics
Society Meeting, Biophysics Society, Baltimore, Maryland. (International)
Page, R. (presented 2004, February). Expression, Purification and Initial Characterization by
NMR Spectroscopy of the Integral Membrane Protein Rv2433c from Mycobacterium
tuberculosis. Poster presentation at Annual Biophysics Society Meeting, Biophysics
Society, Baltimore, Maryland. (International)
Vijayvergiya, V. (presented 2004, February). Single Channel Conductance of Influenza Virus M2
Protein in Planar Lipid Bilayers. Poster presentation at Annual Biophysics Society
Meeting, Biophysics Society, Baltimore, Maryland. (International)
Chekmenev, E. Y. (presented 2004, January). Sample Heat Dissipation Improvement in NMR of
Hydrated Lipids. Poster presentation at 5th Biennial Structural Biology Symposium –
Membranes: A Challenge for Protein Magnetic Resonance, Florida State University,
Tallahassee, FL. (National)
Hu, J. (presented 2004, January). Histidine Protonation in the Transmembrane Sepment of the
M2 roton Channel fom Influenza A Virus. Poster presentation at 5th Biennial Structural
Biology Symposium – Membranes: A Challenge for Protein Magnetic Resonance,
Florida State University, Tallahassee, FL. (National)
Korepanova, A. (presented 2004, January). Overexpression and Purification of Membrane
Proteins from M. tuberculosis in Escherichia coli as Fusions to Maltose Binding Protein.
Poster presentation at 5th Biennial Structural Biology Symposium – Membranes: A
Challenge for Protein Magnetic Resonance, Florida State University, Tallahassee, FL.
(National)
Moore, J. (presented 2004, January). Expression, Purification and Initial Characterization of
Rv2719c, Rv1924c, and Rv1239c Integral Membrane Proteins of M. tuberculosis. Poster
presentation at 5th Biennial Structural Biology Symposium – Membranes: A Challenge
for Protein Magnetic Resonance, Florida State University, Tallahassee, FL. (National)
Page, R. C. (presented 2004, January). Expression, Purification and Initial Characterization by
NMR Spectroscopy of the Integral Membrane Protein Rv2433c from Mycobacterium
tuberculosis. Poster presentation at 5th Biennial Structural Biology Symposium –
Page 38
Vita for Timothy A Cross
Membranes: A Challenge for Protein Magnetic Resonance, Florida State University,
Tallahassee, FL. (National)
Gor'kov, P. L. (presented 2003, November). Large Sample 15N Solid State NMR Facility for
Oriented Membrane Proteins. Poster presentation at Southeastern Magnetic Resonance
Conference, Florida State University, Tallahassee, FL. (Regional)
Hu, J. (presented 2003, November). Histidine Protonation in a Proton Channel from the M2
Transmembrane Segment. Poster presentation at Southeastern Magnetic Resonance
Conference, Florida State University, Tallahassee, FL. (Regional)
Asbury, T. (presented 2003, October). Atomic Refinement Using Correlated Orientational Data
from Solid-State NMR. Poster presentation at Southeastern Magnetic Resonance
Conference, Florida State University, Tallahassee, FL. (Regional)
Li, C. (presented 2003, October). Evaluation of Heteronuclear Decoupling Sequence Applied to
Static Rigid and Hydrated Solids. Poster presentation at Southeastern Magnetic
Resonance Conference, Florida State University, Tallahassee, FL. (Regional)
Mo, Y. (presented 2003, October). Solid State NMR of Membrane Proteins in Different Lipid
Bilayers. Poster presentation at Southeastern Magnetic Resonance Conference, Florida
State University, Tallahassee, FL. (Regional)
Nguyen, H. (presented 2003, October). Semisynthesis of the Influenza Virus M2 Ion Channel
Protein Using a Modified Mycobacterium xenopi GyrA Intein Expression System without
Substituting Amino Acids at the Cleavage Site. Poster presentation at Southeastern
Magnetic Resonance Conference, Florida State University, Tallahassee, FL. (Regional)
Page, R. C. (presented 2003, October). Expression, Purification and Initial Characterization by
NMR Spectroscopy of Multiple Integral Membrane Proteins from Mycobacterium
tuberculosis. Presentation at Southeastern Magnetic Resonance Conference, Florida State
University, Tallahassee, FL. (Regional)
Bertram, R. (presented 2003, March). Atomic Refinement Using Correlated Orientational Data
from Solid-State NMR. Poster presentation at Annual Biophysics Society Meeting,
Biophysics Society, San Antonio, Texas. (International)
Gao, F. (presented 2003, March). Membrane Protein Structural Genomics: Mycobacterium
tuberculosis. Poster presentation at Annual Biophysics Society Meeting, Biophysics
Society, San Antonio, Texas. (International)
Gao, F. (presented 2003, March). Solid State NMR Studies of Membrane Associated Ion
Channels. Poster presentation at Annual Biophysics Society Meeting, Biophysics
Society, San Antonio, Texas. (International)
Page 39
Vita for Timothy A Cross
Hu, J. (presented 2003, March). Exploring the Binding Effect of Amantadine on the Histidine
Side Chain and Backbone of the M2 Protein Transmembrane Segment from Influenza
Virus by Solid State NMR. Poster presentation at Annual Biophysics Society Meeting,
Biophysics Society, San Antonio, Texas. (International)
Li, C. (presented 2003, March). Sensitivity Improvements in Membrane Protein Solid State NMR
Experiments. Poster presentation at Annual Biophysics Society Meeting, Biophysics
Society, San Antonio, Texas. (International)
Quine, J. R. (presented 2003, March). Analysis of Orientational Restraints in NMR. Poster
presentation at Annual Biophysics Society Meeting, Biophysics Society, San Antonio,
Texas. (International)
Vijayvergiya, V. (presented 2003, March). Ion Channel Studies of Influenza virus M2 in planar
lipid bilayers. Poster presentation at Annual Biophysics Society Meeting, Biophysics
Society, San Antonio, Texas. (International)
Gao, F. (presented 2002, November). Over-expression of Integral Membrane Proteins from
Mycobacterium tuberculosis for NMR Structural Genomics Studies. Poster presentation at
Southeast Magnetic Resonance Conference, North Carolina State University, Raleigh,
North Carolina. (Regional)
Tian, C. (presented 2002, November). PISA Wheel Helical Rotational Angle Analysis of m2
Protein Channel from Influenza A Virus. Poster presentation at Southeast Magnetic
Resonance Conference, North Carolina State University, Raleigh, North Carolina.
(Regional)
Gao, F. (presented 2002, October). Integral Membrane Protein Structural Genomics:
Mycobacterium tuberculosis. Poster presentation at ISGO International Conference on
Structural Genomics, Berlin, Germany. (International)
Brey, W. W. (presented 2002, April). Improvements in NMR Probes for Membrane Protein
Studies. Poster presentation at Annual Experimental NMR Conference, Asilomar, CA.
(National)
Hu, J. (presented 2002, April). Solid State NMR Spectroscopy of Histidine-37 in the Proton
Channel Formed by the Transmembrane Peptide, M2-TMP. Poster presentation at
Annual Experimental NMR Conference, Asilomar, CA. (National)
Kim, S. (presented 2002, April). Direct Observation of helical Geometry and Resonance
Assignment in 2D Solid State NMR Spectra. Poster presentation at Annual Experimental
NMR Conference, Asilomar, CA. (National)
Page 40
Vita for Timothy A Cross
Tian, C. (presented 2002, April). Transmembrane Helix Backbone Structural Characterization of
M2 Proton Channel from Influenza A Vrius Using 2D PISEMA Solid State NMR. Poster
presentation at Annual Experimental NMR Conference, Asilomar, CA. (National)
Hu, J. (presented 2002, February). Histidine Residue pH Titration and Amantadine Inhibition
Studies of M2 Protein from Influenza A Vrius by Magic Angle Spinning (MAS) NMR.
Poster presentation at Annual Biophysical Society Meeting, Biophysical Society, San
Francisco, CA. (International)
Kim, S. (presented 2002, February). Analysis and NMR Spectral Simulation of 310, , and
Helices. Poster presentation at Annual Biophysical Society Meeting, Biophysical Society,
San Francisco, CA. (International)
Kim, S. (presented 2002, February). Refined Molecular Model Structure Based on Solid State
NMR Orientational Restraints: A Tetramer Model Structure of Influenza M2 H+ Channel
Transmembrane Region. Poster presentation at Annual Biophysical Society Meeting,
Biophysical Society, San Francisco, CA. (International)
Tian, C. (presented 2002, February). Structural Characterization of M2 Protein from Influenza A
Vrius Using Solution NMR and Solid State NMR. Poster presentation at Annual
Biophysical Society Meeting, Biophysical Society, San Francisco, CA. (International)
Nishimura, K. (presented 2001, November). The Effect of RF Inhomogeneity on Heteronuclear
Dipolar Recoupling in Solid State NMR: Practical Performance of SFAM and REDOR.
Poster presentation at 40th Japan NMR conference, Kyoto Japan. (International)
Tian, C. (presented 2001, November). Initial Structural Characterization of M2 Proton Channel
from Influenza A virus using Solid State NMR. Presentation at International Symposium
of Magnetic resonance Methodology, WuHan, P.R. China. (International)
Fu, R. (presented 2001, October). NMR Spin Locking under Frequency-Switched Lee-Goldburg
(FSLG) Pulse Sequences. Presentation at the 9th Beijing Conference and Exhibition on
Instrumental Analaysis (BCEIA), Beijing, P.R. China. (International)
Gan, Z. (presented 2001, October). High-Field, Fast-MAS NMR of Quadrupolar Nuclei up to 40
kHz and 40T. Presentation at Southeastern Magnetic Resonance Conference, Gainesville,
FL. (Regional)
Hu, J. (presented 2001, October). Imaging Membrane Protein Helical Wheels. Poster
presentation at Southeastern Magnetic Resonance Conference, University of Florida,
Gainsville, FL. (Regional)
Kim, S. (presented 2001, October). Solid state NMR Structure Determination of Membrane
Protein Helices. Presentation at Southeastern Magnetic Resonance Conference,
University of Florida, Gainsville, FL. (Regional)
Page 41
Vita for Timothy A Cross
Gan, Z. (presented 2001, August). High Field, Fast Speed and Satellite Transition MAS NMR of
Quadrupolar Nuclei. Presentation at Rocky Mountain Conference on Analytical
Chemistry, Denver, CO. (International)
Kim, S. (presented 2001, May). Molecular Refinement and Cross-Validation with Solid-State
NMR Orientational Data. Poster presentation at Gordon Resarch Conference,
Computational Aspects of Biomolecular NMR, Il Ciocco, Italy. (International)
Bertram, R. (presented 2001, March). Molecular Refinement and Cross-Validation with Solid
State NMR Orientational Data. Poster presentation at Annual Experimental NMR
Conference, Orlando, FL. (National)
Fu, R. (presented 2001, March). NMR Spin Locking Magnetization under Frequency Switched
Lee-Goldberg (FSLG) Pulse Sequence. Poster presentation at Annual Experimental NMR
Conference, Orlando, FL. (National)
Hu, J. (presented 2001, March). Imaging Membrane Protein Helical Wheels. Poster presentation
at Membrane Protein Structure/Function Keystone Conference, Tahoe City. (National)
Hu, J. (presented 2001, March). Structural Determination of the M2 Transmembrane Peptide
(TMP) H+ Channel from Solid State NMR. Poster presentation at Keystone Conference
on membrane Protein Structure/Function, Tahoe City. (National)
Kim, S. (presented 2001, March). Solid State NMR Structure Determination of Hydrogen
Bonding and Uniformity of membrane Protein Helices. Poster presentation at Annual
Experimental NMR Conference, Orlando, FL. (National)
King, B. (presented 2001, March). Using Nuclear Magnetic Resonance Spectroscopy to Study
the Structure of Humic Acid. Poster presentation at Annual Experimental NMR
Conference, Orlando, FL. (National)
Mo, Y. (presented 2001, March). Structural Studies of the Gramicidin A Monomer in Long
Chain Lipid Bilayers. Poster presentation at Annual Experimental NMR Conference,
Orlando, FL. (National)
Nishimura, K. (presented 2001, March). Experimental Evidence for the Bundle Structure of M2
H+ Channel Transmembrane Peptide (TMP) from Solid-State NMR Distance
Measurements. Poster presentation at Annual Experimental NMR Conference, Orlando,
FL. (National)
Painter, T. A. (presented 2001, March). Wide bore 900 MHz NMR System Fabrication and
Testing. Poster presentation at Annual Experimental NMR Conference, Orlando, FL.
(National)
Page 42
Vita for Timothy A Cross
Tian, C. (presented 2001, March). Structural Insight of Intact M2 Membrane Protein from
Influenza A Virus by 2D PISEMA. Poster presentation at Annual Experimental NMR
Conference, Orlando, FL. (National)
Bertram, R. (presented 2001, February). Molecular Refinement and Cross-Validation with Solid
State NMR Orientational Data. Poster presentation at Annual Biophysical Society
Meeting, Biophysical Society, Boston, MA. (International)
Denny, J. K. (presented 2001, February). PISEMA Powder Patterns and PISA Wheels. Poster
presentation at Annual Biophysical Society Meeting, Biophysical Society, Boston, MA.
(International)
Markham, J. C. (presented 2001, February). A Discrete Conductance Substate in Gramicidin M.
Channels. Poster presentation at Annual Biophysical Society Meeting, Biophysical
Society, Boston, MA. (International)
Mo, Y. (presented 2001, February). The Structural Studies of Gramicidin A in long Lipid
Bilayers. Poster presentation at Annual Biophysical Society Meeting, Biophysical
Society, Boston, MA. (International)
Nishimura, K. (presented 2001, February). Experimental Evidence for the Bundle Structure of
M2 H+ Channel Transmembrane Peptide and Intact Protein from Influenza A Virus from
Solid-State NMR. Poster presentation at Annual Biophysical Society Meeting,
Biophysical Society, Boston, MA. (International)
Schumaker, M. F. (presented 2001, February). A Unified Model of Proton Conductance through
Gramicidin A, B and M. Poster presentation at Annual Biophysical Society Meeting,
Biophysical Society, Boston, MA. (International)
Thompson, K. (presented 2001, February). Gramicidin A Conductance is Enhanced by Phloretin
in Phospholipid but not Monoglyceride Bilayers. Poster presentation at Annual
Biophysical Society Meeting, Biophysical Society, Boston, MA. (International)
Quine, J. R. (presented 2001, January). Transmembrane protein Structure from Mathematical
Analysis. Poster presentation at National American Mathematical Society Meeting,
American Mathematical Society, New Orleans, LA. (National)
Grage, S. (presented 2000, March). Solid-state F-19 NMR Studies of Gramicidin A in Oriented
Membranes. Poster presentation at Experimental NMR Conference, Asilomar, CA.
(National)
Kim, S. (presented 2000, March). Complete Cross-Validation and R-Factor Calculation of
Solid-State NMR Derived Structures. Poster presentation at Experimental NMR
Conference, Asilomar, CA. (National)
Page 43
Vita for Timothy A Cross
Tian, C. (presented 2000, March). Structural Characterization by Solid-State NMR of Intact M2
Protein and the Transmembrane Peptide. Poster presentation at Experimental NMR
Conference, Asilomar, CA. (National)
Cole, C. (presented 2000, February). Current-Voltage Relationships of 5- and 6-F Trp Analogs
of Gramicidin A. Poster presentation at Annual Biophysical Society Meeting, Biophysical
Society, New Orleans, LA. (International)
Denny, J. K. (presented 2000, February). Simulating Membrane Protein Helical Wheels from
PISEMA Spectra. Poster presentation at Annual Biophysical Society Meeting,
Biophysical Society, New Orleans, LA. (International)
Kim, S. (presented 2000, February). Structural Validation of Solid-State NMR Derived
Structures. Poster presentation at Annual Biophysical Society Meeting, Biophysical
Society, New Orleans, LA. (International)
Nishimura, K. (presented 2000, February). Heteronuclear Dipolar Recoupling in Solid-State
MAS NMR in the Presence of RF Pulse Inhomogeneity: Pratical Performance of REDOR
and SFAM. Poster presentation at Annual Biophysical Society Meeting, Biophysical
Society, New Orleans, LA. (International)
Tian, C. (presented 2000, February). Structural Characterization of Intact M2 Protein by Solid
State NMR. Poster presentation at Annual Biophysical Society Meeting, Biophysical
Society, New Orleans, LA. (International)
Wang, J. (presented 2000, February). High Resolution Structure of the M2 Transmembrane
Peptide (TMP) H+ Channel from Solid State NMR. Poster presentation at Annual
Biophysical Society Meeting, Biophysical Society, New Orleans, LA. (International)
Wang, J. (presented 2000, February). Structural Characterization of the M2 Transmembrane
Peptide (TMP). Poster presentation at Annual Biophysical Society Meeting, Biophysical
Society, New Orleans, LA. (International)
Zhou, Z. (presented 2000, February). 15N NMR Study of the Ionization Properties of the
Influenza Virus Fusion Petide in Zwitterionic Phospholipid Dispersions. Poster
presentation at Annual Biophysical Society Meeting, Biophysical Society, New Orleans,
LA. (International)
Denny, J. K. (presented 2000, January). Orientational constraints and nuclear magnetic
resonance, II: PISEMA wheels. Poster presentation at AMS/MAA National Joint
Meetings, AMS/MAA. (National)
Denny, J. (presented 1999, November). Simulating Membrane Protein Helical Wheels from
PISEMA Spectra. Poster presentation at SEMRC, Florida State University, Tallahassee,
FL. (Regional)
Page 44
Vita for Timothy A Cross
Fu, R. (presented 1999, November). PISEMA Wheels. Poster presentation at SEMRC, Florida
State University, Tallahassee, FL. (Regional)
Fu, R. (presented 1999, November). Protein Structural Determination Using Solid State NMR
Spectroscopy. Poster presentation at SEMRC, Florida State University, Tallahassee, FL.
(Regional)
Gan, Z. (presented 1999, November). Solid state NMR of Quadrupolar and Low-Gamma Nuclei
at 19.6 T and 25 T. Poster presentation at SEMRC, Florida State University, Tallahassee,
FL. (Regional)
Kim, S. (presented 1999, November). Cross-Validation of Solid-state NMR Derived Structures.
Poster presentation at SEMRC, Florida State University, Tallahassee, FL. (Regional)
Tian, C. (presented 1999, November). Structural Characterization by Solid State NMR of Intact
M2 Protein and the Synthetic Transmmbrane Peptide. Poster presentation at SEMRC,
Florida State University, Tallahassee, FL. (Regional)
Wang, J. (presented 1999, November). High Resolution Structure of the M2 Transmembrane
Peptide (TMP) H+ Channel from Solid State NMR. Poster presentation at SEMRC,
Florida State University, Tallahassee, FL. (Regional)
Gallagher, G. J. (presented 1999, July). Depth Measurements in membranes via Solid-State
NMR. Poster presentation at Protein Society Meeting, Protein Society. (National)
Soghomonian, V. (presented 1999, March). Development of Resistive Magnets for NMR
Applications. Poster presentation at Experimental NMR Conference, Orlando, FL.
(National)
Song, Z. (presented 1999, March). Orientational Constraints for the Influenza Viral M2 Protein
from 2D-PISEMA in Solid-State NMR. Poster presentation at Experimental NMR
Conference, Orlando, FL. (National)
Tian, F. (presented 1999, March). 13C Polarization and Spin Diffusion in a Lipid Bilayer Bound
Polypeptide by Solid State NMR. Poster presentation at Experimental NMR Conference,
Orlando, FL. (National)
Wang, J. (presented 1999, March). Investigation of the Proton Transfer Regulatory Role of
Histidine-37 in the Influenza A Virus M2 Protein by Solid State NMR. Poster presentation
at Experimental NMR Conference, Orlando, FL. (National)
Cole, C. D. (presented 1999, February). The Effects of 5-Florination of Trp9, 11, 13, or 15 of
Gramicidin channel Conductance. Poster presentation at Annual Biophysics Society
Meeting, Biophysics Society, Baltimore, MD. (International)
Page 45
Vita for Timothy A Cross
Denny, J. (presented 1999, February). The Discrete Frenet Frame and Coiled Coil Proteins.
Poster presentation at Annual Biophysics Society Meeting, Biophysics Society,
Baltimore, MD. (International)
Gao, F. (presented 1999, February). Structural Mapping of E. coli Lactose Permease Using 19F
Solid State NMR Spectroscopy. Poster presentation at Annual Biophysics Society
Meeting, Biophysics Society, Baltimore, MD. (International)
Kovacs, F. (presented 1999, February). Refinement of a Structural Model of the M2 Ion Channel
from Influenza A. Poster presentation at Annual Biophysics Society Meeting, Biophysics
Society, Baltimore, MD. (International)
Phillips, L. R. (presented 1999, February). In Gramicidin Hydrogen Transport the Rate Limiting
Water Reorientation Must be Initiated at the Channel Exit. Poster presentation at Annual
Biophysics Society Meeting, Biophysics Society, Baltimore, MD. (International)
Song, Z. (presented 1999, February). Structural and Chemical Characterization by Solid State
NMR of a Proton Channel. Poster presentation at Annual Biophysics Society Meeting,
Biophysics Society, Baltimore, MD. (International)
Thompson, N. (presented 1999, February). Kinetic Modeling of 5F-Trp13 Gramicidin A Channel
Currents. Poster presentation at Annual Biophysics Society Meeting, Biophysics Society,
Baltimore, MD. (International)
Wang, J. (presented 1999, February). 2H Solid State NMR of Ethanolamine and Tyrosine
Analogs of Gramicidin A in Lipid Bilayers. Poster presentation at Annual Biophysics
Society Meeting, Biophysics Society, Baltimore, MD. (International)
Denny, J. K. (presented 1999). The discrete Frenet frame and coiled proteins. Poster
presentation at Program in Mathematics and Molecular Biology VI: Understanding
Structure, Santa Fe, NM. (National)
Soghomonian, V. (presented 1998, October). NMR at High Fields: 20 & 25 T. Presentation at
The American Chemical Society North Jersey Section NMR Topical Group, American
Chemical Society, New Jersey. (National)
Cotten, M. (presented 1998, March). Determination of Gramicidin Dimer Structures in Hydrated
Phospholipid Bilayers by Solid State NMR. Poster presentation at ENC Meeting, ENC,
Asilomar, CA. (International)
Kovacs, F. (presented 1998, March). Structural Characterization of the M2 Transmembrane
Peptide using Orientational Constraints from Solid State NMR. Poster presentation at
ENC Meeting, ENC, Asilomar, CA. (International)
Page 46
Vita for Timothy A Cross
Tian, F. (presented 1998, March). Orientational Constraints from Hydrated Powder Samples by
Two-Dimensional PISEMA Sequence. Poster presentation at ENC Meeting, ENC,
Asilomar, CA. (International)
Cotten, M. (presented 1998, February). Use of 5-Flurotryptophan and Solid State NMR to Probe
the Role of Long-Range Electrostatic Interactions in the Gramicidin A Channel. Poster
presentation at Annual Biophysics Society Meeting, Biophysics Society, Kansas City,
KS. (International)
Kovacs, F. A. (presented 1998, February). Structural Characterization of the M2
Transmembrane Peptide Backbone Using Solid State NMR. Poster presentation at Annual
Biophysics Society Meeting, Biophysics Society, Kansas City, KS. (International)
Quine, J. (presented 1998, February). Tilt of Membrane a Helices Using Solid State NMR. Poster
presentation at Annual Biophysics Society Meeting, Biophysics Society, Kansas City,
KS. (International)
Thulin, C. (presented 1998, February). 5-Flurotryptophan of Trp-13 in Gramicidin A Can
Increase (Lecithin) or Decrease (Monoolein) Channel Conductance. Poster presentation
at Annual Biophysics Society Meeting, Biophysics Society, Kansas City, KS.
(International)
Tian, F. (presented 1998, February). Structural Basis for the Gramicidin A Channel Specificity
Probed by Solid State NMR. Poster presentation at Annual Biophysics Society Meeting,
Biophysics Society, Kansas City, KS. (International)
Tian, F. (presented 1997, March). Cation Binding Induced Changes in N-15 CSA in a
Polypeptide. Poster presentation at ENC Meeting, ENC, Orlando, FL. (International)
Cotten, M. (presented 1997, February). Tryptophan as Switch for the Conformational
Conversion of Gramicidin in Lipid Bilayers. Poster presentation at Annual Biophysics
Society Meeting, Biophysics Society, New Orleans, LA. (International)
Kovacs, F. A. (presented 1997, February). Structural Characterization of the M2
Transmembrane Peptide Backbone Using Solid State NMR. Poster presentation at Annual
Biophysics Society Meeting, Biophysics Society, New Orleans, LA. (International)
Xu, F. (presented 1997, February). Solvent Mediated Conformational Interconversion: A
Catalytic Role for Protic Solvents. Poster presentation at New Fronteirs in NMR
Keystone Conference, Taos. (International)
Soghomonian, V. (presented 1996, September). NMR at Very High Field (24T) in Resistive
Magnets: Results and Challenges. Presentation at AMPERE Congress, Cantebury,
England. (International)
Page 47
Vita for Timothy A Cross
Ketchem, R. R. (presented 1996, March). Protein Structure Characterization using Solid State
NMR Orientational Data. Poster presentation at ENC Meeting, ENC, Asilomar, CA.
(International)
Soghomonian, V. (presented 1996, March). NMR at Very High Field (24T) in Resistive Magnets:
Results and Challenges. Presentation at Experimental NMR Conference, Asilomar, CA.
(International)
Soghomonian, V. (presented 1996, March). NMR at Very High Field (24T) in Resistive Magnets:
Results and Challenges. Poster presentation at ENC Meeting, ENC, Asilomar, CA.
(International)
Tian, F. (presented 1996, March). Dipolar Oscillations in Membrane-Bound Polypeptides. Poster
presentation at ENC Meeting, ENC, Asilomar, CA. (International)
Ketchem, R. R. (presented 1996, February). A Complete Method for Determining Protein
Structure from Solid-State NMR Orientational Data. Poster presentation at Annual
Biophysics Society Meeting, Biophysics Society, Baltimore, MD. (International)
Tian, F. (presented 1996, February). Solid State NMR of Gramicidin A to Study Channel
Selectivity and Gramicidin Analogs to Probe the Functional Roles of Tryptophan. Poster
presentation at Annual Biophysics Society Meeting, Biophysics Society, Baltimore, MD.
(International)
Wang, A. (presented 1996, February). Conformational Interconversion of a Polypeptide Induced
by 'Catalytic' Solvent. Poster presentation at Annual Biophysics Society Meeting,
Biophysics Society, Baltimore, MD. (International)
Xu, F. (presented 1996, February). The Solvent Effects on the Conformational Interconversion of
a Polypeptide and their Implications for Membrane Proteins in the Lipid Environment.
Poster presentation at Annual Biophysics Society Meeting, Biophysics Society,
Baltimore, MD. (International)
Ketchem, R. R. (presented 1995, December). A Complete Method for Determining Protein
Structure from Soli-State NMR Orientational Data. Poster presentation at SEMRC,
Florida State University, Tallahassee, FL. (Regional)
Kuhns, P. L. (presented 1995, December). NMR in a 24.6T, 10 ppm Resistive Magnet at the
National High Magnetic Field Laboratory. Poster presentation at SEMRC, Florida State
University, Tallahassee, FL. (Regional)
Tian, F. (presented 1995, December). Solid-State NMR of Gramicidin A to Study Channel
Selectivity and Gramicidin Analogs to Probe the Functional Roles of Tryptophan. Poster
presentation at SEMRC, Florida State University, Tallahassee, FL. (Regional)
Page 48
Vita for Timothy A Cross
Wang, A. (presented 1995, December). Conformational Interconversion of a Polypeptide
Induced by "Catalytic" Solvent. Poster presentation at SEMRC, Florida State University,
Tallahassee, FL. (Regional)
Ketchem, R. R. (presented 1995, April). High Definition Protein Structure Solid-State NMR
Derived Orientational Constraints. Poster presentation at Keystone Conference,
Keystone. (National)
Xu, F. (presented 1995, April). Determination and Identification of the Interaction of Gramicidin
A with Solvent in an Ethanol/Benzene Solvent System using 2D NMR Spectroscopy.
Poster presentation at Keystone Conference, Keystone. (National)
Ketchem, R. R. (presented 1995, February). Global Refinement of the Gramicidin Channel
Improved by New Solid State NMR Constraints. Poster presentation at 1995 Biophysics
Society Meeting, Biophysics Society, San Francisco, CA. (International)
Tian, F. (presented 1995, February). Polypeptide Ion Channels as Studied by Solid State NMR.
Poster presentation at 1995 Biophysics Society Meeting, Biophysics Society, San
Franciscso, CA. (International)
Huo, S. (presented 1995). Proton Exchange and Molecular Dynamics in the Gramicidin Channel
Dissolved in a Lipid Environment: A Solid State NMR Study of Gramicidin Analogs.
Poster presentation at Physical Phenomina at High Magnetic Fields Conference, National
High Magnetic Field Laboratory, Tallahassee, FL. (National)
Huo, S. (presented 1995). Proton Exchange of Gramicidin A Channel with Water in Lipid
Environment Investigated by Solid State NMR and NMR Studies of Gramicidin A
Analogs. Poster presentation at ENC Meeting, ENC, Boston, MA. (International)
Ketchem, R. R. (presented 1995). Biological Solid-State NMR Spectroscopy - a Need for High
Fields. Poster presentation at Physical Phenomina at High Magnetic Fields Conference,
National High Magnetic Field Laboratory, Tallahassee, FL. (National)
Asakura, T. (presented 1994, August). Structural Analysis of Uniaxially aligned Protein Fiber by
Solid State 15N and 13C NMR. Poster presentation at XVIth International Conference on
Magnetic Resonance in Biological Systems, Veldhoven, The Netherlands. (International)
Arumugam, S. (presented 1994). 2H, 15N and 23Na NMR Studies on the Functional Aspects of
the Gramicidin Channel. Poster presentation at Annual Biophysics Meeting, Biophysics
Meeting, New Orleans, LA. (International)
Arumugam, S. (presented 1994). Functional Aspects of the Gramicidin Channel as Studied by
2H, 15N and 23Na NMR. Poster presentation at ENC Meeting, ENC, Asilomar, CA.
(International)
Page 49
Vita for Timothy A Cross
Hu, W. (presented 1994). Structure, Dynamics and Function in the Gramicidin Channel. Poster
presentation at Magnetic Resonance Gordon Conference, Henniker, New Hampshire.
(National)
Ketchem, R. R. (presented 1994). Backbone Structural Refinement and Dynamics from Solid
State NMR Derived Tensors and Orientational Constraints. Poster presentation at ENC
Meeting, ENC, Asilomar, CA. (International)
Ketchem, R. R. (presented 1994). High Definition Structure and Refinement of the Gramicidin
Channel Backbone and Sidechains. Poster presentation at Annual Biophysics Meeting,
Biophysics Meeting, New Orleans, LA. (International)
Lee, K.-C. (presented 1994). Molecular Dynamics of Gramicidin A by Solid-State NMR. Poster
presentation at Annual Biophysics Meeting, Biophysics Meeting, New Orleans, LA.
(International)
Lee, K.-C. (presented 1994). Polypeptide Sidechain Structure and Dynamics in a Hydrated Lipid
Bilayer Environment. Poster presentation at ENC Meeting, ENC, Asilomar, CA.
(International)
Vaughn, J. B., Jr. (presented 1994). Determination and Characterization of the Dependence of
the Conformations of Gramicidin A upon Benzene/Alcohol solvent Mixtures using 2D
NMR Spectroscopy. Poster presentation at ENC Meeting, ENC, Asilomar, CA.
(International)
Ketchem, R. R. (presented 1993). Dynamics of the Gramicidin A Channel: Molecular
Reorientation Rates and Backbone Librations. Poster presentation at Annual Biophysics
Meeting, Biophysics Meeting, Washington. (International)
Ketchem, R. R. (presented 1993). High Resolution Protein Structure Determination by Solid
State NMR. Poster presentation at Annual Biophysics Meeting, Biophysics Meeting,
Washington. (International)
Ketchem, R. R. (presented 1993). High Resolution Protein Structure Determination by Solid
State NMR. Poster presentation at Keystone Symposia on Molecular and Cell Biology:
Joint Session - Fronteirs of NMR in Molecular Biology III and Prospects and Progress in
Drug Design Based on Peptides and Proteins, Taos. (International)
Ketchem, R. R. (presented 1993). High Resolution Protein Structure Determination by Solid
State NMR. Poster presentation at Proteins Gordon Conference, Tilton, NH. (National)
Lazo, N. D. (presented 1993). Probing the Dynamics of Gramicidin A by 15N Solid State NMR of
Rapidly Frozen Samples. Poster presentation at Experimental NMR Conference, St.
Louis. (National)
Page 50
Vita for Timothy A Cross
Lee, K.-C. (presented 1993). Global and Sidechain Dynamics of Gramicidin A by 2H Solid State
NMR. Poster presentation at Experimental NMR Conference, St. Louis. (National)
Ketchem, R. R. (presented 1992). Structural Details of the Gramicidin Channel Conformation by
Solid State NMR. Poster presentation at Annual Biophysics Society Meeting, Biophysics
Society, Houston, TX. (International)
Lazo, N. (presented 1992). Structural Dynamics of Gramicidin A as Revealed by
Variable-Temperature Solid-State 15N and 13C NMR. Poster presentation at
Experimental NMR Conference, Asilomar, CA. (National)
Lee, K.-C. (presented 1992). Sidechain Structure and Dynamics in Gramicidin A Using 2H and
15N Solid State NMR. Poster presentation at Experimental NMR Conference, Asilomar,
CA. (National)
Nicholson, L. K. (presented 1992). A Method for Studying the Structure of Uniaxially Aligned
Molecular Systems Using Solid State NMR: Application to Silk Fibroin Fibers. Poster
presentation at Annual Biophysics Society Meeting, Biophysics Society, Houston, TX.
(International)
North, C. (presented 1992). 15N T1 Relaxation Times Indicate Backbone Librations of the
Gramicidin A Cation Channel on the Same Time Scale as Ion Transport. Poster
presentation at Experimental NMR Conference, Asilomar, CA. (National)
North, C. L. (presented 1992). Long Correlation Times for Peptide Backbone Motions Measured
by 15N Solid State NMR in Gramicidin A. Poster presentation at Annual Biophysics
Society Meeting, Biophysics Society, Houston, TX. (International)
Pascal, S. M. (presented 1992). A Right Handed Parallel Double Helical Structure of Gramicidi
A by High Resolution NMR. Poster presentation at Annual Biophysics Society Meeting,
Biophysics Society, Houston, TX. (International)
Pascal, S. M. (presented 1992). High Resolution Structure of Isolated Gramicidin A Species in
Various Solvent Systems by 2D NMR. Poster presentation at Experimental NMR
Conference, Asilomar, CA. (National)
Mai, W. (presented 1991). The Gramicidin Channel Backbone Folding Motif by Solid State
NMR. Poster presentation at Annual Biophysics Society Meeting, Biophysics Society,
San Francisco, CA. (International)
Nicholson, L. K. (presented 1991). Solid-State NMR for the Study of Structure and Dynamics of
Membrane-Bound Proteins. Presentation at Aspects of Drug Design Conference,
Beckman Institute for Advanced Science and Technology, University of Illinois at
Champaign-Urbana, Champaign-Urbana IL. (International)
Page 51
Vita for Timothy A Cross
Nicholson, L. K. (presented 1991). Structural and Dynamic Studies of Silk Fibroin Using Solid
State 15N NMR. Poster presentation at Annual Biophysics Society Meeting, Biophysics
Society, San Francisco, CA. (International)
North, C. (presented 1991). 15N T1 Relaxation Times Interpreted by a Detailed Structural and
Dynamic Model of the Gramicidin Cation Channel. Poster presentation at Experimental
NMR Conference, St. Louis, MO. (National)
Pascal, S. M. (presented 1991). Isolation and Solution NMR Structure Determination of a
Gramicidin A Dimer. Poster presentation at Experimental NMR Conference, St. Louis,
MO. (National)
Pascal, S. M. (presented 1991). Isolation and Solution NMR Structure Determination of a
Gramicidin A Dimer. Poster presentation at Annual Biophysics Society Meeting,
Biophysics Society, San Francisco, CA. (International)
Pascal, S. M. (presented 1991). Isolation and Solution NMR Structure Determination of a
Gramicidin A Dimer. Poster presentation at Keystone Colloquium: Fronteirs of NMR in
Molecular Biology, Keystone. (International)
Wang, C. (presented 1991). 2H, 13C and 15N NMR of the Gramicidin Channel in a Lipid
Bilayer: Structural Constraints. Poster presentation at Experimental NMR Conference,
St. Louis, MO. (National)
Chiu, S.-W. (presented 1990). Molecular Dynamics Computations and Solid State NMR of the
Gramicidin Cation Channel. Poster presentation at Annual Biophysical Society Meeting,
Biophysical Society. (International)
Chiu, S.-W. (presented 1990). Molecular Dynamics Computations and Solid State NMR of the
Gramicidin Cation Channel. Poster presentation at Biophysics Satellite Conference on
Expanding Fronteirs in Polypeptide and Protein Structural Research, Whistler, British
Columbia. (International)
Nicholson, L. K. (presented 1990). Dynamics of the Gramicidin Cation Channel using Solid
State 15N NMR. Poster presentation at Biophysics Satellite Conference on Expanding
Fronteirs in Polypeptide and Protein Structural Research, Whistler, British Columbia.
(International)
Nicholson, L. K. (presented 1990). Molecular Dynamics Computations and Solid State NMR of
the Gramicidin Cation Channel. Poster presentation at Experimental NMR Conference,
Asilomar, CA. (National)
Page 52
Vita for Timothy A Cross
Teng, Q. (presented 1990). 15N and 13C Chemical Shift and 14N Electric Field Gradient Tensor
Orientations with respect to the molecular frame of the Peptide Linkages in the
Gramicidin Cation Channel. Poster presentation at Experimental NMR Conference,
Asilomar, CA. (National)
Teng, Q. (presented 1990). Determination of Torsion Angles in the Backbone of the Gramicidin
Cation Channel by Solid State NMR. Poster presentation at Annual Biophysical Society
Meeting, Biophysical Society. (International)
Teng, Q. (presented 1990). Determination of Torsion Angles in the Backbone of the Gramicidin
Cation Channel by Solid State NMR. Poster presentation at 10th International Biophysics
Congress, Vancover, British Columbia. (International)
Brenneman, M. T. (presented 1989). A New Method for Determining Protein Structure Using
Solid State NMR: The 'Metric Method. Poster presentation at Annual Biophysical Society
Meeting, Biophysical Society. (International)
Chiu, S.-W. (presented 1989). Molecular Dynamics Computations and Solid State NMR of the
Gramicidin Cation Channel. Poster presentation at New York Ion Channel Meeting, New
York. (Regional)
Nicholson, L. K. (presented 1989). Conformational Substates in the Polypeptide Backbone of the
Gramicidin A Transmembrane Channel. Presentation at Annual Biophysical Society
Meeting, Biophysical Society. (International)
Nicholson, L. K. (presented 1989). Peptide Linkage Dynamics in the N-terminal Region of the
Gramicidin A Transmembrane Channel Using Solid State 15N NMR. Poster presentation
at Experimental NMR Conference, Asilomar, CA. (National)
Teng, Q. (presented 1989). Backbone Structure of a Dipeptide Segment of the Gramicidin A
Transmembrane Channel from Solid State 15N NMR. Poster presentation at Experimental
NMR Conference, Asilomar, CA. (National)
Brenneman, M. T. (presented 1988). Protein Structure and Dynamics of the Gramicidin Channel
by Solid State NMR. Poster presentation at American Physical Society Conference on
Biological Physics, American Physical Society. (National)
Fields, C. G. (presented 1988). Solid Phase Synthesis and Solid State 15N NMR Spectroscopy of
Gramicidins A, B and C. Poster presentation at Annual FASEB Meeting, FASEB.
(National)
LoGrasso, P. V. (presented 1988). Gramicidin A Structure in Lipid Bilayers. Poster presentation
at Annual Biophysical Society Meeting, Biophysical Society. (International)
Page 53
Vita for Timothy A Cross
Nicholson, L. K. (presented 1988). Dynamics of the Gramicidin A Transmembrane Channel by
Solid State 15N NMR. Poster presentation at Experimental NMR Conference, Asilomar,
CA. (National)
Nicholson, L. K. (presented 1988). Peptide Backbone Dynamics of Gramicidin A in Lipid
Bilayers Using Solid State 15N NMR Spectroscopy. Poster presentation at Annual
Biophysical Society Meeting, Biophysical Society. (International)
Teng, Q. (presented 1988). Solid State NMR Study of the Structure of Gramicidin A. Poster
presentation at Experimental NMR Conference, Asilomar, CA. (National)
Moll, F. (presented 1987). Solid State 15N NMR Studies of Uniform an Specific Site 15N Labeled
Gramicidin A' in an Oriented Lipid Bilayer. Poster presentation at Annual Biophysical
Society Meeting, Biophysical Society. (International)
Nicholson, L. K. (presented 1987). Solid State NMR Studies of Isotopically Labeled Gramicidin
A in an Oriented Lipid Bilayer. Poster presentation at Experimental NMR Conference,
Asilomar, CA. (National)
Guy, C. A. (presented 1986). Solid State NMR Spectroscopy of Oriented Gramicidin Cation
Channels in a Lipid Bilayer. Poster presentation at The Experimental NMR Conference,
Asilomar, CA. (National)
Invited Lectures and Readings of Original Work
Cross, T. A. (2010, October). Structure and Function of a Flu Drug Target. Delivered at Florida
State University. (Local)
Cross, T. A. (2009, April). Biochemical Activity in a Hydrocarbon Environment: the challenges
and opportunities for membrane proteins. Delivered at Iowa State University. (National)
Cross, T. A. (2009, March). Lipid Bilayers: an essential environment for understanding
membrane protein structure-function relationships. Delivered at Virginia Tech. (Local)
Cross, T. A. (2008, October). Why Structural Biology Needs Solid State NMR Spectroscopy.
Delivered at Clark University, Worcester, MA. (National)
Cross, T. A. (2008, February). " Drug Targets and Prospects for for Drug-Screening using Solid
State NMR. Delivered at University of Pisa, Department of Chemistry. (International)
Cross, T. A. (2008, February). Sample preparation for Aligned Sample Solid State NMR.
Delivered at University of Florence, Center for Magnetic Resonance, Florence, Italy.
(International)
Page 54
Vita for Timothy A Cross
Cross, T. A. (2008, February). The M2 Proton Channel from Influenza A Virus: Structural and
Functional Studies by NMR. Delivered at University of Florence, Center for Magnetic
Resonance, Florence, Italy. (International)
Cross, T. A. (2008, February). Understanding Biological Solid State NMR of Aligned Samples.
Delivered at University of Florence, Center for Magnetic Resonance, Florence, Italy.
(International)
Cross, T. A. (2007, October). The Balance of Molecular Interactions in Membrane Proteins:
Characterizations by Solid State NMR Spectroscopy. Delivered at University of Florida,
Dept. of Chemistry, Gainesville, FL. (Local)
Cross, T. A. (2007, July). Structure-Function Studies of Membrane Protein Drug Targets by
NMR. Delivered at University of Texas Health Center at Tyler, Tyler, TX. (National)
Cross, T. A. (2007, January). The M2 Proton Channel from Influenza A Virus: Structural and
Functional Studies by NMR. Delivered at Duke University. (National)
Cross, T. A. (2006, November). The M2 Acid Channel from Influenza A Virus: Structural and
Functional Studies by NMR. Delivered at University of South Alabama. (National)
Cross, T. A. (2006, October). The M2 Proton Channel from Influenza A Virus: Structural and
Functional Studies by NMR. Delivered at Eppley Cancer Institute, University of
Nebraska Medical Center. (National)
Cross, T. A. (2006, April). The M2 Proton Channel from Influenza A Virus: Structural and
Functional Studies by NMR. Delivered at Burnham Institute, La Jolla, CA. (National)
Cross, T. A. (2005, December). High Field NMR Spectroscopy of Membrane Proteins. Delivered
at South-East Center for NMR Spectroscopy, webcast. (Regional)
Cross, T. A. (2005, December). Ion Interactions with the Gramicidin Channel & Proton
Interactions with the M2 Channel. Delivered at Queens University, Kingston, Ontario.
(International)
Cross, T. A. (2005, August). Grant Support from the National Science Foundation: An
Experience. Delivered at Florida State University, Tallahassee, FL. (Local)
Cross, T. A. (2005, August). Grant Support from the National Science Foundation: An
Experience. Delivered at Florida State University, College of Medicine, Tallahassee, FL.
(Local)
Cross, T. A. (2005, May). The M2 Proton Channel from Influenza A Virus: Structural and
Functional Studies by Solid State NMR. Delivered at University of Pennsylvania.
(National)
Page 55
Vita for Timothy A Cross
Cross, T. A. (2005, January). Ion Interactions with the Gramicidin Channel and Proton
Interactions with the M2 Channel. Delivered at Center for Cellular and Molecular
Biology, Hyderabad, India. (International)
Cross, T. A. (2004, April). Membrane Proteins: Challenges for Structural Biology by Solid State
NMR. Delivered at University of Delaware. (National)
Cross, T. A. (2004, March). Membrane Protein Structural Genomics: A Multi-Technology
Challenge. Delivered at University of Virginia – Chalottesville, Chalottesville, VA.
(National)
Cross, T. A. (2003, May). Membrane Protein Structural Biology and Structural Genomics:
Challenges for Solid State NMR. Delivered at University of California - Berkeley,
Berkeley, CA. (National)
Cross, T. A. (2003, April). Membrane Proteins: Challenges for Structural Biology by Solid State
NMR. Delivered at Brandeis University. (National)
Cross, T. A. (2003, January). Membrane Protein Challenges for Structural Biology by Solid
State NMR. Delivered at Yale University. (National)
Cross, T. A. (2002, May). Membrane Protein Structure from Solid-State NMR: PISA Wheels.
Delivered at Ohio University. (National)
Cross, T. A. (2002, April). Membrane Protein. Delivered at University of Minnesota. (National)
Cross, T. A. (2002, February). Membrane Protein Structural Elucidation: PISA Wheels from
Solid State NMR Spectroscopy. Delivered at Vanderbilt University. (National)
Cross, T. A. (2002, February). Solid State NMR of Membrane Proteins. Delivered at Vanderbilt
University. (National)
Cross, T. A. (2001, November). Towards a Three Dimensional Structure of the M2 Proton
Channel from Influenza A Virus Using Solid-State NMR of Aligned Liquid Crystalline
Lipid Bilayers. Delivered at Rockefeller University. (National)
Gao, F. P. (2001, October). Membrane Protein Structural Characterization using Solid State
Nuclear magnetic Resonance. Delivered at Shanghai Jiao University, Shanghai, P.R.
China. (International)
Cross, T. A. (2000, November). Imaging Membrane Protein Helical Wheels by Solid State NMR
Spectroscopy: M2 Protein from Influenza A. Delivered at " Programs of Structural
Biology and Molecular Biophysics, University of Pittsburg, Pittsburg, PA. (National)
Page 56
Vita for Timothy A Cross
Cross, T. A. (2000, March). Imaging membrane Protein Helical Wheels. Delivered at Tokyo
University of Agriculture & Technology, Tokyo, Japan. (International)
Cross, T. A. (2000, March). Imaging membrane Protein Helical Wheels. Delivered at Himeji
Institute of Technology, Harima Science Garden City, Japan. (International)
Cross, T. A. (2000, March). Imaging membrane Protein Helical Wheels. Delivered at Kobe
University, Kobe, Japan. (International)
Cross, T. A. (2000, March). Three-Dimensional Protein Structures: Mathematical and Technical
Challenges. Delivered at Department of Mathematics, Florida State University,
Tallahassee, FL. (Local)
Cross, T. A. (2000, January). Chemistry and Biology at the Frontiers of High Field NMR
Spectroscopy. Delivered at Department of Chemistry, Florida institute of Technology,
Miami, FL. (State)
Cross, T. A. (1999, September). Imaging Protein Helical Wheels. Delivered at Department of
Biochemistry, Oxford University. (International)
Cross, T. A. (1999, April). Solid State NMR Channel Characterization in Lamellar Phase Lipids:
Peptides to Proteins. Delivered at Department of Physiology and Biophysics, Case
Western Reserve University. (National)
Cross, T. A. (1999, April). Solid State NMR Channel Characterization in Lamellar Phase Lipids:
Peptides to Proteins. Delivered at Department of Biophysics, University of Michigan.
(National)
Cross, T. A. (1999, April). The NHMFL NMR Program and The National Magnetic Resonance
Collaboratorium. Delivered at Program in Structural Biology, Case Western Reserve
University. (National)
Cross, T. A. (1997, November). From Membrane-Bound Polypeptides to Proteins: High
Resolution Structure by NMR. Delivered at Chemistry Department, Florida State
University, Tallahassee, FL. (Local)
Cross, T. A. (1997, May). High Resolution Structure in a Lipid Bilayer Environment: Solid State
NMR from Polypeptides to Proteins. Delivered at Department of Biochemistry,
Molecular Biology, and Cell Biology, Northwestern University, Evanston, IL. (National)
Cross, T. A. (1997, February). Membrane Polypeptides and Their Environment: Structure,
Stability and Flexibility. Delivered at Department of Chemistry Tuscon. (National)
Cross, T. A. (1996, November). High Resolution Structure in Anisotropic Environments by Solid
State NMR. Delivered at University of Hokkaido, Sapporo, Japan. (International)
Page 57
Vita for Timothy A Cross
Cross, T. A. (1996, November). The Unique Advantages of NMR Spectroscopy. Delivered at
Tokyo University of Agriculture & Technology, Tokyo, Japan. (International)
Cross, T. A. (1996, April). High Resolution Structure & Dynamics by Solid state NMR:
Gramicidin A in Hydrated Lipid Bilayers. Delivered at Department of Chemical
Engineering, Florida State University & Florida A&M University, Tallahassee, FL.
(Local)
Cross, T. A. (1996, April). High Resolution Structure in Membranes by Solid State NMR: The
Gramicidin A Channel. Delivered at Department of Chemistry, Ohio University.
(National)
Cross, T. A. (1996, March). High Resolution Dynamics in a Membrane-Bound Polypeptide by
Solid State NMR. Delivered at Himeji Institute of Technology, Himeji, Japan.
(International)
Cross, T. A. (1996, March). High Resolution Dynamics in a Membrane-Bound Polypeptide by
Solid State NMR. Delivered at Institute of Chemical Engineering, Kyoto University,
Kyoto, Japan. (International)
Cross, T. A. (1996, March). High Resolution Dynamics in a Membrane-Bound Polypeptide by
Solid State NMR. Delivered at Department of Synthetic Chemistry and Biological
Chemistry, Kyoto University, Kyoto, Japan. (International)
Cross, T. A. (1996, March). High Resolution Dynamics in a Membrane-Bound Polypeptide by
Solid State NMR. Delivered at Tokyo University of Agriculture & Technology, Tokyo,
Japan. (International)
Cross, T. A. (1995, September). Membrane Proteins: Functional Implications from High
Resolution Structure and Dynamics of Polypeptides in a Bilayer Environment. Delivered
at Institute of Molecular Biophysics, Florida State University, Tallahassee, FL. (Local)
Cross, T. A. (1995, June). High Resolution Structure & Dynamics by Solid state NMR:
Gramicidin A in Hydrated Lipid Bilayers. Delivered at University of Basel, Basel,
Switzerland. (International)
Cross, T. A. (1995, May). High Resolution Structure & Dynamics by Solid state NMR:
Gramicidin A in Hydrated Lipid Bilayers. Delivered at University of Louisville,
Louisville, KY. (National)
Cross, T. A. (1995, March). High Resolution Structure & Dynamics by Solid state NMR:
Gramicidin A in Hydrated Lipid Bilayers. Delivered at Cornell University. (National)
Page 58
Vita for Timothy A Cross
Cross, T. A. (1994, November). Nuclear Magnetic Resonance: A Unique Spectroscopy.
Delivered at Tokyo University of Agriculture and Technology, Tokyo, Japan.
(International)
Cross, T. A. (1994, May). Molecular Dynamics by Solid State NMR and Functional Correlations
in a Membrane-Bound Polypeptide. Delivered at Universite de Lausanne, Lausanne,
Switzerland. (International)
Cross, T. A. (1993, December). NMR Spectroscopy Applied to Structure-Function Relationships
in Membrane Proteins. Delivered at Battelle - Pacific Northwest Laboratories. (National)
Cross, T. A. (1993, November). Solid-State NMR for Elucidating Structure-Function
Relationships. Delivered at Chemistry Department, Florida State University, Tallahassee,
FL. (Local)
Cross, T. A. (1993, October). Solid-State NMR for Elucidating Structure-Function Relationships.
Delivered at Chemistry Department, University of South Florida. (State)
Cross, T. A. (1993, October). Solid-State NMR for Elucidating Structure-Function
Relationships: The Gramicidin Cationic Channel. Delivered at Chemistry Department,
University of Virginia. (National)
Cross, T. A. (1993, March). The Biological Membrane: An Environment that Traps Protein
Conformation. Delivered at Los Alamos National Laboratory, INC Division, Los
Alamos, NM. (National)
Cross, T. A. (1992, October). Gramicidin: A Mechanism for Protein Insertion. Delivered at
Washington State University, Pullman, Washington. (National)
Cross, T. A. (1992, October). Structure and Dynamics of the Gramicidin A Cation Channel by
Solid State NMR. Delivered at Washington State University, Pullman, Washington.
(National)
Cross, T. A. (1992, May). Structure and Dynamics of the Gramicidin A Cation Channel by Solid
State NMR. Delivered at Georgia Institute of Technology, Atlanta, Georgia. (National)
Cross, T. A. (1992, February). Structure and Dynamics of the Gramicidin A Cation Channel by
Solid State NMR. Delivered at Columbia University, New York, New York. (National)
Cross, T. A. (1991, July). High Resolution Molecular Dynamics in Proteins by Solid State 15N
and 13C NMR. Delivered at Otsuka Denshi, Shinjuku, Japan. (International)
Cross, T. A. (1991, July). Protein Structure Determination by Solid State NMR Spectroscopy.
Delivered at Yokohama University, Yokohama, Japan. (International)
Page 59
Vita for Timothy A Cross
Cross, T. A. (1991, July). Science and Facilities for the New U.S. National High Magnetic Field
Laboratory. Delivered at Tokyo University, Tokyo, Japan. (International)
Cross, T. A. (1991, July). Solid State NMR Analysis of the Structure of Antibiotics. Delivered at
Pola Co, Totsuka, Japan. (International)
Cross, T. A. (1991, July). The Advantages of Solid State 15N NMR for Protein Structure and
Dynamics Elucidation. Delivered at Tokyo University of Agriculature and Technology,
Tokyo, Japan. (International)
Cross, T. A. (1991, April). Protein Structure and Dynamics by Solid State NMR Spectroscopy.
Delivered at University of Illinois, Department of Physiology and Biophysics & the
Beckman Institute, Champaign-Urbana, IL. (National)
Cross, T. A. (1990, October). The Future of NMR Spectroscopy: A View from the National High
Magnetic Field Laboratory. Delivered at MARTECH Seminar, Tallahassee, FL. (Local)
Cross, T. A. (1989, May). Atomic Resolution Structure and Dynamics of the Gramicidin Channel
by Solid State NMR Spectroscopy. Delivered at Procter and Gamble - Miami Valley Labs,
Cincinatti, OH. (National)
Cross, T. A. (1989, April). Atomic Resolution Structure and Dynamics of the Gramicidin
Channel by Solid State NMR Spectroscopy. Delivered at University of Washington,
Seattle, WA. (Local)
Cross, T. A. (1989, February). Polypeptide Structure and Dynamics by Solid State NMR.
Delivered at University of Tokyo for Agriculture and Technology. (International)
Cross, T. A. (1989, January). 15N Solid State NMR of the Gramicidin A Channel. Delivered at
Washington University, St. Louis, MO. (National)
Cross, T. A. (1988, May). The Function of the Gramicidin Cation Channel: The Beginnings of
an Explanation from Solid State NMR. Delivered at FSU Chemistry Department,
Tallahassee, FL. (Local)
Cross, T. A. (1987, October). -History Dependent Gramicidin Structures. Delivered at Procter
and Gamble - Miami Valley Labs, Cincinatti, OH. (National)
Cross, T. A. (1987, April). Solid State 15N NMR Approach for Determining Polypeptide
Structure and Dynamics. Delivered at Syracuse University, Syracuse, NY. (National)
Cross, T. A. (1987, February). 15N NMR Studies of Gramicidin A in a Lipid Bilayer. Delivered
at Fl. Biochemists. (State)
Page 60
Vita for Timothy A Cross
Cross, T. A. (1986, October). NMR Spectroscopy and the Future of Chemistry. Delivered at
Davidson College, Davidson, North Carolina. (Local)
Cross, T. A. (1986, May). Isotopic Labeling of Gramicidin A' and its Incorporation into
Oriented Lipid Bilayers. Delivered at Procter and Gamble - Miami Valley Labs,
Cincinatti, OH. (National)
Cross, T. A. (1986, May). NMR Spectroscopy and the Future of Chemistry. Delivered at Trinity
College, Hartford, CT. (Local)
Cross, T. A. (1986, May). Structural and Dynamic Characterizations of Biological
Macromolecular Complexes by Solid State NMR. Delivered at Atlanta University,
Atlanta, GA. (National)
Cross, T. A. (1985, September). Dynamic and Structural Elucidation of Biomolecules by Solid
State NMR. Delivered at Bristol Myers, Rochester, NY. (National)
Cross, T. A. (1985, May). Dynamic and Structural Elucidation of Biomolecules by Solid State
NMR. Delivered at Procter and Gamble - Miami Valley Labs, Cincinatti, OH. (National)
Cross, T. A. (1985, March). Dynamic and Structural Elucidation of Biomolecules by Solid State
NMR. Delivered at IMB Minisymposium, Tallahassee, FL. (Local)
Cross, T. A. (1984, September). In Vivo NMR Spectroscopy: Probe Development and
Application. Delivered at Smith, Kline, French, and Beckman, Philadelphia, PA.
(National)
Patented Inventions
Cross, T. A., Brey, W. W., Smirnov, A., & Chekmenev, E. Y. (submitted). Solid State NMR
Method for Screening Cell Membrane Protein Binding Drug Candidates. U.S. Patent
7,674,595.
Cross, T. A., Brey, W. W., Smirnov, A., & Chekmenev, E. Y. (submitted). Solid State NMR
Method for Screening Cell Membrane Protein Binding Drug Candidates. U.S. Patent
7,678,546.
Page 61
Vita for Timothy A Cross
Contracts and Grants
Contracts and Grants Funded
Cross, Timothy A (PI), & Zhou, Huan-Xiang (Co-PI). (Apr 2015–Mar 2017). Membrane Protein
Structures and Interactions in the M. Tuberculosis Divisome. Funded by National
Institute of Allergy. (1R01AI119178). Total award $1,496,222.
Cross, Timothy A (Co-PI), Trociewitz, Ulf P (Co-PI), Brey, William W (PI), & Larbalestier,
David C (Co-PI). (Aug 2014–Apr 2017). Solution-Based Biomolecular NMR at 24 T
Fields Using New High Temperature Superco. Funded by National Institute of General
Medical Sciences. (R21GM111302). Total award $637,500.
Cross, Timothy A (PI), & Brey, William W (Co-PI). (Jul 2014–Jul 2017). 14.1 T Magnet With
+/- 1280 G Field Regulation and Integrated MAS Cryogenic. Funded by National
Institutes of Health. (S10OD018519). Total award $1,376,600.
Cross, Timothy A (PI), Fu, Riqiang (Co-PI), & Zhou, Huan-Xiang (Co-PI). (Aug 2011–Jul
2015). Correlations: Structure-Dynamics-Function in Channels. Funded by National
Institute of Allergy. (R01AI023007). Total award $1,848,827.
Cross, Timothy A (Co-PI), Bird, Mark D (Co-PI), Gan, Zhehong (Co-PI), Brey, William W (PI),
& Grant, Samuel (Co-PI). (Oct 2010–Sep 2016). MRI: Development of an NMR Console
for the 36 T Series. Funded by National Science Foundation. (1039938). Total award
$1,300,000.
Cross, Timothy A (PI), & Brey, William W (Co-PI). (Aug 2009–Jul 2015). ikM Tuberculosis
Membrane Protein Pharmaceutical Targets. Funded by National Institute of Allergy.
(P01AI074805). Total award $8,719,341.
Cross, Timothy A (PI), & Gao, Fei (Co-PI). (Dec 2007–Nov 2014). Four Mtb Membrane
Proteins: Structure and Function. Funded by National Institute of Allergy.
(R01AI073891). Total award $2,042,627.
Cross, Timothy A (Co-PI), Brey, William W (PI), & Gor'kov, Petr L (Co-PI). (Jun 2007–Jan
2012). Unrestricted Grant for Support of Postdoctoral Associate. Funded by Bruker
BioSpin Corporation. Total award $100,000.
Cross, Timothy A (Co-PI), Bird, Mark D (PI), & Brandt, Bruce L (Co-PI). (Aug 2006–Nov
2014). Series Connected Hybrid Construction Phase. Funded by National Science
Foundation. (0603042). Total award $11,699,643.
Page 62
Vita for Timothy A Cross
Cross, Timothy A (PI), & Page, Richard C (Co-PI). (Jul 2006–Apr 2008). Structure
Determination of kdpC: the C Subunit of the Potassium Transporting ATPase, kdp.
Funded by American Heart Association. Total award $43,540.
Cross, Timothy A (Co-PI), & Moore, Jacob D (PI). (Dec 2005–Dec 2008). Membrane Protein
Backbone Structure Determination. Funded by National Institute of Neurological
Disorders. (F31NS054494). Total award $84,145.
Cross, Timothy A (PI), & Moore, Jacob D (Co-PI). (Jul 2005–Dec 2005). Tuberculosis
Percarditis: Alpha Helical Membrane Protein. Funded by American Heart Association.
(0515194B). Total award $10,500.
Cross, Timothy A (PI), & Nguyen, Hau Thi B (Co-PI). (Jul 2005–Jun 2007). Structural Analysis
of Integral Membrane Proteins. Funded by American Heart Association. (0515199B).
Total award $42,000.
Cross, Timothy A (PI), Fu, Riqiang (Co-PI), & Zhou, Huan-Xiang (Co-PI). (Mar 2005–Feb
2011). Correlations: Structure-Dynamics-Functions in Channels. Funded by National
Institute of Allergy. (R01AI023007). Total award $1,726,292.
Cross, Timothy A (Co-PI), (Co-PI), Bird, Mark D (PI), & Brandt, Bruce L (Co-PI). (Jul
2004–Jun 2007). Series Connected Hybrid. Funded by National Science Foundation.
(DMR-0412169). Total award $1,803,092.
Cross, Timothy A (PI), Quine, John R (Co-PI), & Fu, Riqiang (Co-PI). (Feb 2003–Jan 2007).
Membrane Protein Solid State NMR: PISEMA Developme. Funded by National Science
Foundation. (0235774). Total award $516,254.
Cross, Timothy A (PI), Taylor, Kenneth A (Co-PI), Quine, John R (Co-PI), Marshall, Alan G
(Co-PI), Chapman, Michael S (Co-PI), & Bertram, Richard (Co-PI). (Sep 2001–Aug
2007). Membrane Protein Structural Genomics: M. Tuberculosis. Funded by National
Institute of General Medical Sciences. (P01 GM64676). Total award $7,979,166.
Cross, Timothy A (PI). (Jan 2001–Dec 2020). CROS-SRAD ALLOCATION. Funded by FSU.
Total award $19,841.
Cross, Timothy A (PI), & Fu, Riqiang (Co-PI). (Mar 2000–Feb 2005). Correlations: Structure
Dynamics Functions in Cha. Funded by National Institute of Allergy. (5 R01 AI23007).
Total award $1,593,208.
Contracts and Grants Pending
Cross, Timothy A (PI), & Brey, William W (Co-PI). (May 2016). National Resource For
Advanced Nmr Technology. Submitted to National Institutes of Health.
Page 63
Vita for Timothy A Cross
Service
Florida State University
FSU University Service
Member, Executive Committee, Center for Advancing Exercise and Nutrition Research on
Aging (2008–present).
Member, Biomedical Advisory Committee (2007–present).
Member, College Area Promotion and Tenure Committee (2005–2006).
Member, Doctoral Directive Status Committee (2005–2006).
Member, Science Area Promotion and Tenure Committee (2005–2006).
Member, Faculty Search Committee - Martech (2004–2005).
Member, Faculty Search Committee – Chemical Engineering (2004–2005).
Member, Arts & Sciences Computing Technology Committee (2003–2005).
Member, College Committee on the Interactions between Programs and Departments
(1991–1993).
Member, Science Area Committee (1991–1993).
Member, Science Center Planning Committee (1991–1993).
FSU Department Service
Member, Graduate Curriculum and Advising Committee (2009–present).
Member, Awards Committee (2008–present).
Member, NMR Facility Committee (2007–present).
Member, Courtesy Appointment Committee (2004–present).
Division Head, Biochemistry Division Head (2002–present).
Chair, BASS Lab Facility Committee (2000–2009).
Page 64
Vita for Timothy A Cross
Member, Staff Evaluation Committee (2007–2008).
Member, Chemistry Executive Committee (2003–2008).
Director and Committee Chair, The NMR Facility (2004–2007).
Member, Taxol Royalty Committee (2002–2006).
Chair, Merit Raise Committee (2003–2004).
Director, The NMR Facility (1984–2004).
Member, MASS Spec Lab Facility Committee (2002–2003).
Member, Search Committee for Senior NMR Spectroscopist (1999–2003).
Member, Committee on Courtesy Appointments (2000–2002).
Member, Search Committee for Senior Computationalist (1999–2001).
Chair, Departmental Safety Committee (1995–1997).
Member, Graduate Recruiting Committee (1993–1995).
Chair, Magnet Lab and Martech Selection Committee (1992–1995).
ex Officio Member, NMR Facility Committee (1984–1995).
ex Officio Member, Biological Science Executive Committee (1992–1993).
ex Officio Member, Chemistry Executive Committee (1992–1993).
Member, Merit Raise Committee (1991–1992).
Chair, Search Committee for Head of the NMR Program in the NHMFL (1990–1992).
Member, Ad Hoc Committee to evaluate William Armstrong (1991).
Member, Ad Hoc Committee to Evaluate Paul Bash (1990–1991).
Member, Liason Search Committee (1990–1991).
Member, BASS Lab Committee (1989–1991).
Member, Graduate Advisory Committee (1986–1991).
Page 65
Vita for Timothy A Cross
Member, Capital Equipment Committee (1989–1990).
Member, Curriculum Committee (1989–1990).
Member, Awards Committee (1988–1989).
Chair, Computer Development Committee (1987–1988).
Member, General Development Committee (1986–1987).
FSU Institute or Center Service
Member, NHMFL Promotion Committee for Research Faculty (2010–present).
Member, NHMFL Staff Leadership Committee (2005–present).
Member, NHMFL Executive Committee (1994–present).
Member, IMB Search Committee Chair for new Director (2006–2007).
Member, NHMFL Renewal Committee (2005–2007).
Member, NHMFL Promotion Committee (2004–2007).
Member, NHMFL Diversity Task Force (2004–2006).
Member, NHMFL Search for Scholar Scientist in MRI (2004–2006).
Member, NHMFL Named Postdoctoral Evaluation Committee (2004–2005).
Chair, Search for Rising Star in NMR (2002–2004).
Member, IMB Research Training Grant Committee (1998–2003).
Member, AMRIS Facility Advisory Committee (1998–2002).
Project Director, NHMFL Keck Program (1996–2000).
Member, IMB Executive Committee (1997–1998).
Member, IMB RTG Committee (1996–1998).
Member, Search Committee for Solid-State NMR Spectroscopist (1996–1998).
Page 66
Vita for Timothy A Cross
Member, Search Committee for NMR/Biomaterials Faculty in Chemical Engineer (1996–1997).
Member, CIMAR Faculty Committee (1995–1996).
Acting Director, NHMFL New Initiatives (1995–1996).
Chair, Search Committee for EMR Spectroscopist (1995–1996).
Chair, Search Committee for RF Specialist (1995–1996).
Member, Magnet Lab Search Committee (1992–1994).
Member, Structural Biology Director's Search Committee (1990–1994).
Program Director, Structural Biology Program (1990–1994).
Program Director, Institute of & Graduate Program in Molecular Biophysics (1990–1993).
Chair, NHMFL Search Oversight Committee (1990–1993).
Member, NHMFL Facilities Committee (1990–1992).
Member, NHMFL Planning Committee (1990–1992).
Co-coordinator, 1st International NHMFL NMR Workshop (1991).
Member, Structural Biology Search Committee (1990–1991).
Member, Structural Biology Seminar Committee (1989–1991).
Member, Molecular Biophysics Graduate Program Committee (1987–1990).
The Profession
Editorial Board Membership(s)
Journal of Magnetic Resonance (1998–present).
Biophysical Journal (1998–2004).
Service to Professional Associations
Member, Biophysics Society Public Affairs Committee (2005–present).
Page 67
Vita for Timothy A Cross
Advisory Board, Magnetic Resonance in Chemistry (1997–present).
NIBIB Advisory Committee, UCSD Resource for Solid State NMR (1997–present).
NMR & MRI User Program Director, NHMFL (1995–present).
NCRR Advisory Committee, University of California, San Diego Resource for Solid State NMR
(1995–present).
External Advisory Committee, Canadian High Field Solid State NMR Facility (2009–2013).
Organizing Committee, 16th Meeting International Society for Magnetic Resonance (2007).
Member, Biophysics Society 50th Anniversary Committee (2005–2007).
Co-Chair, Biophysics Society Funding Agency Subcommittee (2005–2007).
Member, International Advisory Committee – 16th ISMAR Conference, Taiwan (2005–2007).
Member, Advisory Board of the Magnetic Resonance in Chemistry (1997–2006).
Member, Biophysics Society Legislative Action Committee (2005).
Member, Biophysics Society Program Committee (2005).
Organizing Chair, 15th Meeting International Society for Magnetic Resonance (2004).
Program Chair, 48th Annual Meeting Biophysical Society (2004).
Member, Biophysics Society Nominating Committee (2003–2004).
Chair, Biophysics Society Program Committee (2002–2004).
Editor, Editorial Board - Biophysical Journal (1998–2004).
Editor, Editorial Board – Journal Magnetic Resonance (1998–2003).
Elected Member, Biophysical Society Council (2000–2002).
Member, NIH BBCB Study Section (1995–1999).
Member, NSF Biophysics Review Panel (1989–1992).
Page 68
Vita for Timothy A Cross
Service to Other Universities
PhD Dissertation Review for Brian Hare, Yale University (1994).
Page 69
Related documents