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The Center of Molecular Biology and Neuroscience
Pubications in peer-reviewed journals
Molecular biology
Bjoras M., Seeberg E., Luna L., Pearl L. H., Barrett T. E. (2002) Reciprocal "flipping" underlies substrate
recognition and catalytic activation by the human 8-oxo-guanine DNA glycosylase. J.Mol.Biol. 317
(2):171-177
van den Bout C. J., Machon O., Rosok O. O., Backman M., Krauss S. (2002) The mouse enhancer
element D6 directs Cre recombinase activity in the neocortex and the hippocampus. Mech.Dev. 110 (12):179-182
Winther-Larsen H. C., Koomey M. (2002) Transcriptional, chemosensory and cell-contact-dependent
regulation of type IV pilus expression. Curr.Opin.Microbiol. 5 (2):173-178
Anensen H., Provan F., Lian A. T., Reinertsen S. H., Ueno Y., Matsuda A., Seeberg E., Bjelland S.
(2001) Mutations induced by 5-formyl-2'-deoxyuridine in Escherichia coli include base substitutions that
can arise from mispairs of 5-formyluracil with guanine, cytosine and thymine. Mutat.Res. 476 (1-2):99107
Bjelland S., Anensen H., Knaevelsrud I., Seeberg E. (2001) Cellular effects of 5-formyluracil in DNA.
Mutat.Res. 486 (2):147-154
Collins R. F., Davidsen L., Derrick J. P., Ford R. C., Tonjum T. (2001) Analysis of the PilQ secretin from
Neisseria meningitidis by transmission electron microscopy reveals a dodecameric quaternary structure.
J.Bacteriol. 183 (13):3825-3832
Eide L., Fosberg E., Hoff E., Seeberg E. (2001) Overexpression of endonuclease III protects Escherichia
coli mutants defective in alkylation repair against lethal effects of methylmethanesulphonate. FEBS Lett.
491 (1-2):59-62
Eide L., Luna L., Gustad E. C., Henderson P. T., Essigmann J. M., Demple B., Seeberg E. (2001)
Human endonuclease III acts preferentially on DNA damage opposite guanine residues in DNA.
Biochemistry 40 (22):6653-6659
Harmsen D., Singer C., Rothganger J., Tonjum T., de Hoog G. S., Shah H., Albert J., Frosch M. (2001)
Diagnostics of neisseriaceae and moraxellaceae by ribosomal DNA sequencing: ribosomal differentiation
of medical microorganisms. J.Clin.Microbiol. 39 (3):936-942
Klungland A., Paulsen R., Rolseth V., Yamada Y., Ueno Y., Wiik P., Matsuda A., Seeberg E., Bjelland S.
(2001) 5-Formyluracil and its nucleoside derivatives confer toxicity and mutagenicity to mammalian cells
by interfering with normal RNA and DNA metabolism. Toxicol.Lett. 119 (1):71-78
Knaevelsrud I., Ruoff P., Anensen H., Klungland A., Bjelland S., Birkeland N. K. (2001) Excision of uracil
from DNA by the hyperthermophilic Afung protein is dependent on the opposite base and stimulated by
heat-induced transition to a more open structure. Mutat.Res. 487 (3-4):173-190
Koomey M. (2001) Implications of molecular contacts and signaling initiated by Neisseria gonorrhoeae.
Curr.Opin.Microbiol. 4 (1):53-57
Olsen A. K., Bjortuft H., Wiger R., Holme J., Seeberg E., Bjoras M., Brunborg G. (2001) Highly efficient
base excision repair (BER) in human and rat male germ cells. Nucleic Acids Res. 29 (8):1781-1790
Park H. S., Wolfgang M., van Putten J. P., Dorward D., Hayes S. F., Koomey M. (2001) Structural
alterations in a type IV pilus subunit protein result in concurrent defects in multicellular behaviour and
adherence to host tissue. Mol.Microbiol. 42 (2):293-307
Rognes T. (2001) ParAlign: a parallel sequence alignment algorithm for rapid and sensitive database
searches. Nucleic Acids Res. 29 (7):1647-1652
Souza-Pinto N. C., Eide L., Hogue B. A., Thybo T., Stevnsner T., Seeberg E., Klungland A., Bohr V. A.
(2001) Repair of 8-oxodeoxyguanosine lesions in mitochondrial dna depends on the oxoguanine dna
glycosylase (OGG1) gene and 8-oxoguanine accumulates in the mitochondrial dna of OGG1-defective
mice. Cancer Res. 61 (14):5378-5381
Tonjum T., Seebereg E. (2001) Microbial fitness and genome dynamics. Trends Microbiol. 9 (8):356358
Winther-Larsen H. C., Hegge F. T., Wolfgang M., Hayes S. F., van Putten J. P., Koomey M. (2001)
Neisseria gonorrhoeae PilV, a type IV pilus-associated protein essential to human epithelial cell
adherence. Proc.Natl.Acad.Sci.U.S.A 98 (26):15276-15281
Hartmann A., Halvorsen C. E., Jenssen T., Bjorneklett A., Brekke I. B., Bakke S. J., Hirschberg H.,
Tonjum T., Gaustad P. (2000) Intracerebral abscess caused by Nocardia otitidiscaviarum in a renal
transplant patient--cured by evacuation plus antibiotic therapy. Nephron 86 (1):79-83
Huang C., Wolfgang M. C., Withey J., Koomey M., Friedman D. I. (2000) Charged tmRNA but not
tmRNA-mediated proteolysis is essential for Neisseria gonorrhoeae viability. EMBO J. 19 (5):1098-1107
Le Page F., Klungland A., Barnes D. E., Sarasin A., Boiteux S. (2000) Transcription coupled repair of 8oxoguanine in murine cells: the ogg1 protein is required for repair in nontranscribed sequences but not in
transcribed sequences. Proc.Natl.Acad.Sci.U.S.A 97 (15):8397-8402
Luna L., Bjoras M., Hoff E., Rognes T., Seeberg E. (2000) Cell-cycle regulation, intracellular sorting and
induced overexpression of the human NTH1 DNA glycosylase involved in removal of
formamidopyrimidine residues from DNA. Mutat.Res. 460 (2):95-104
Machon O., Backman M., Julin K., Krauss S. (2000) Yeast two-hybrid system identifies the ubiquitinconjugating enzyme mUbc9 as a potential partner of mouse Dac. Mech.Dev. 97 (1-2):3-12
Mehl A., Rolseth V., Gordon S., Bjoraas M., Seeberg E., Fonnum F. (2000) Brain hypoplasia caused by
exposure to trichlorfon and dichlorvos during development can be ascribed to DNA alkylation damage
and inhibition of DNA alkyltransferase repair. Neurotoxicology 21 (1-2):165-173
Rognes T., Seeberg E. (2000) Six-fold speed-up of Smith-Waterman sequence database searches using
parallel processing on common microprocessors. Bioinformatics. 16 (8):699-706
Wolfgang M., van Putten J. P., Hayes S. F., Dorward D., Koomey M. (2000) Components and dynamics
of fiber formation define a ubiquitous biogenesis pathway for bacterial pili. EMBO J. 19 (23):6408-6418
Alseth I., Eide L., Pirovano M., Rognes T., Seeberg E., Bjoras M. (1999) The Saccharomyces cerevisiae
homologues of endonuclease III from Escherichia coli, Ntg1 and Ntg2, are both required for efficient
repair of spontaneous and induced oxidative DNA damage in yeast. Mol.Cell Biol. 19 (5):3779-3787
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Caubit X., Thangarajah R., Theil T., Wirth J., Nothwang H. G., Ruther U., Krauss S. (1999) Mouse Dac, a
novel nuclear factor with homology to Drosophila dachshund shows a dynamic expression in the neural
crest, the eye, the neocortex, and the limb bud. Dev.Dyn. 214 (1):66-80
Forest K. T., Dunham S. A., Koomey M., Tainer J. A. (1999) Crystallographic structure reveals
phosphorylated pilin from Neisseria: phosphoserine sites modify type IV pilus surface chemistry and fibre
morphology. Mol.Microbiol. 31 (3):743-752
Klungland A., Rosewell I., Hollenbach S., Larsen E., Daly G., Epe B., Seeberg E., Lindahl T., Barnes D.
E. (1999) Accumulation of premutagenic DNA lesions in mice defective in removal of oxidative base
damage. Proc.Natl.Acad.Sci.U.S.A 96 (23):13300-13305
Klungland A., Hoss M., Gunz D., Constantinou A., Clarkson S. G., Doetsch P. W., Bolton P. H., Wood R.
D., Lindahl T. (1999) Base excision repair of oxidative DNA damage activated by XPG protein. Mol.Cell
3 (1):33-42
Shadidy M., Caubit X., Olsen R., Seternes O. M., Moens U., Krauss S. (1999) Biochemical analysis of
mouse FKBP60, a novel member of the FKPB family. Biochim.Biophys.Acta 1446 (3):295-307
Wolfgang M., van Putten J. P., Hayes S. F., Koomey M. (1999) The comP locus of Neisseria
gonorrhoeae encodes a type IV prepilin that is dispensable for pilus biogenesis but essential for natural
transformation. Mol.Microbiol. 31 (5):1345-1357
Allunans J., Bjoras M., Seeberg E., Bovre K. (1998) Production, isolation and purification of bacteriocins
expressed by two strains of Neisseria meningitidis. APMIS 106 (12):1181-1187
Berdal K. G., Johansen R. F., Seeberg E. (1998) Release of normal bases from intact DNA by a native
DNA repair enzyme. EMBO J. 17 (2):363-367
Bergan T., Gaustad P., Hoiby E. A., Berdal B. P., Furuberg G., Baann J., Tonjum T. (1998) Antibiotic
resistance of pneumococci in Norway. Int.J.Antimicrob.Agents 10 (1):77-81
Delghandi M., Utsi E., Krauss S. (1998) Saami mitochondrial DNA reveals deep maternal lineage
clusters. Hum.Hered. 48 (2):108-114
Gran C., Boyum A., Johansen R. F., Lovhaug D., Seeberg E. C. (1998) Growth inhibition of granulocytemacrophage colony-forming cells by human cytidine deaminase requires the catalytic function of the
protein. Blood 91 (11):4127-4135
Holme J. A., Bjorge C., Trbojevic M., Olsen A. K., Brunborg G., Soderlund E. J., Bjoras M., Seeberg E.,
Scholz T., Dybing E., Wiger R. (1998) Effects of chemical-induced DNA damage on male germ cells.
Arch.Toxicol.Suppl 20:151-160
Koomey M. (1998) Competence for natural transformation in Neisseria gonorrhoeae: a model system for
studies of horizontal gene transfer. APMIS Suppl 84:56-61
Levy L. M., Attwell D., Hoover F., Ash J. F., Bjoras M., Danbolt N. C. (1998) Inducible expression of the
GLT-1 glutamate transporter in a CHO cell line selected for low endogenous glutamate uptake. FEBS
Lett. 422 (3):339-342
Nornes S., Clarkson M., Mikkola I., Pedersen M., Bardsley A., Martinez J. P., Krauss S., Johansen T.
(1998) Zebrafish contains two pax6 genes involved in eye development. Mech.Dev. 77 (2):185-196
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Pettersson B., Kodjo A., Ronaghi M., Uhlen M., Tonjum T. (1998) Phylogeny of the family Moraxellaceae
by 16S rDNA sequence analysis, with special emphasis on differentiation of Moraxella species.
Int.J.Syst.Bacteriol. 48 Pt 1:75-89
Rognes T., Seeberg E. (1998) SALSA: improved protein database searching by a new algorithm for
assembly of sequence fragments into gapped alignments. Bioinformatics. 14 (10):839-845
Tonjum T., Caugant D. A., Dunham S. A., Koomey M. (1998) Structure and function of repetitive
sequence elements associated with a highly polymorphic domain of the Neisseria meningitidis PilQ
protein. Mol.Microbiol. 29 (1):111-124
Tonjum T., Welty D. B., Jantzen E., Small P. L. (1998) Differentiation of Mycobacterium ulcerans, M.
marinum, and M. haemophilum: mapping of their relationships to M. tuberculosis by fatty acid profile
analysis, DNA-DNA hybridization, and 16S rRNA gene sequence analysis. J.Clin.Microbiol. 36 (4):918925
Wolfgang M., Lauer P., Park H. S., Brossay L., Hebert J., Koomey M. (1998) PilT mutations lead to
simultaneous defects in competence for natural transformation and twitching motility in piliated Neisseria
gonorrhoeae. Mol.Microbiol. 29 (1):321-330
Wolfgang M., Park H. S., Hayes S. F., van Putten J. P., Koomey M. (1998) Suppression of an absolute
defect in type IV pilus biogenesis by loss-of-function mutations in pilT, a twitching motility gene in
Neisseria gonorrhoeae. Proc.Natl.Acad.Sci.U.S.A 95 (25):14973-14978
Bjoras M., Luna L., Johnsen B., Hoff E., Haug T., Rognes T., Seeberg E. (1997) Opposite basedependent reactions of a human base excision repair enzyme on DNA containing 7,8-dihydro-8oxoguanine and abasic sites. EMBO J. 16 (20):6314-6322
Drake S. L., Sandstedt S. A., Koomey M. (1997) PilP, a pilus biogenesis lipoprotein in Neisseria
gonorrhoeae, affects expression of PilQ as a high-molecular-mass multimer. Mol.Microbiol. 23 (4):657668
Klungland A., Lindahl T. (1997) Second pathway for completion of human DNA base excision-repair:
reconstitution with purified proteins and requirement for DNase IV (FEN1). EMBO J. 16 (11):3341-3348
Kodjo A., Richard Y., Tonjum T. (1997) Moraxella boevrei sp. nov., a new Moraxella species found in
goats. Int.J.Syst.Bacteriol. 47 (1):115-121
Koomey M. (1997) Bacterial pathogenesis: a variation on variation in Lyme disease. Curr.Biol. 7
(9):R538-R540
Lindahl T., Barnes D. E., Klungland A., Mackenney V. J., Schar P. (1997) Repair and processing events
at DNA ends. Ciba Found.Symp. 211:198-205
Lindbrathen A., Gaustad P., Hovig B., Tonjum T. (1997) Direct detection of Mycobacterium tuberculosis
complex in clinical samples from patients in Norway by ligase chain reaction. J.Clin.Microbiol. 35
(12):3248-3253
Marsteinstredet U., Brunborg G., Bjoras M., Soderlund E., Seeberg E., Kronberg L., Holme J. A. (1997)
DNA damage induced by 3-chloro-4-(dichloromethyl)-5-hydroxy-2[5H]-furanone (MX) in HL-60 cells and
purified DNA in vitro. Mutat.Res. 390 (1-2):171-178
Petrini B., Bauer J., Hoffner S., Miorner H., Tonjum T. (1997) [Molecular mycobacterium-diagnostics.
Weapon against increased global spread of tuberculosis]. Lakartidningen 94 (41):3612-4, 3616
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Roldan-Arjona T., Wei Y. F., Carter K. C., Klungland A., Anselmino C., Wang R. P., Augustus M., Lindahl
T. (1997) Molecular cloning and functional expression of a human cDNA encoding the antimutator
enzyme 8-hydroxyguanine-DNA glycosylase. Proc.Natl.Acad.Sci.U.S.A 94 (15):8016-8020
Sandkvist M., Michel L. O., Hough L. P., Morales V. M., Bagdasarian M., Koomey M., DiRita V. J.,
Bagdasarian M. (1997) General secretion pathway (eps) genes required for toxin secretion and outer
membrane biogenesis in Vibrio cholerae. J.Bacteriol. 179 (22):6994-7003
Tonjum T., Koomey M. (1997) The pilus colonization factor of pathogenic neisserial species: organelle
biogenesis and structure/function relationships--a review. Gene 192 (1):155-163
Bjelland S., Seeberg E. (1996) Different efficiencies of the Tag and AlkA DNA glycosylases from
Escherichia coli in the removal of 3-methyladenine from single-stranded DNA. FEBS Lett. 397 (1):127129
Bjoras M., Gjesdal O., Erickson J. D., Torp R., Levy L. M., Ottersen O. P., Degree M., Storm-Mathisen J.,
Seeberg E., Danbolt N. C. (1996) Cloning and expression of a neuronal rat brain glutamate transporter.
Brain Res.Mol.Brain Res. 36 (1):163-168
Eide L., Bjoras M., Pirovano M., Alseth I., Berdal K. G., Seeberg E. (1996) Base excision of oxidative
purine and pyrimidine DNA damage in Saccharomyces cerevisiae by a DNA glycosylase with sequence
similarity to endonuclease III from Escherichia coli. Proc.Natl.Acad.Sci.U.S.A 93 (20):10735-10740
Kubota Y., Nash R. A., Klungland A., Schar P., Barnes D. E., Lindahl T. (1996) Reconstitution of DNA
base excision-repair with purified human proteins: interaction between DNA polymerase beta and the
XRCC1 protein. EMBO J. 15 (23):6662-6670
Lehmann A. R., Bridges B. A., Hanawalt P. C., Johnson R. T., Kanaar R., Krokan H. E., Kyrtopoulos S.,
Lambert B., Melton D. W., Moustacchi E., Natarajan A. T., Radman M., Sarasin A., Seeberg E., Smerdon
M. J., Smith C. A., Smith P. J., Thacker J., Thomale J., Waters R., Weeda G., West S. C., van Zeeland A.
A., Zdzienicka M. Z. (1996) Workshop on processing of DNA damage. Mutat.Res. 364 (3):245-270
Nornes S., Mikkola I., Krauss S., Delghandi M., Perander M., Johansen T. (1996) Zebrafish Pax9
encodes two proteins with distinct C-terminal transactivating domains of different potency negatively
regulated by adjacent N-terminal sequences. J.Biol.Chem. 271 (43):26914-26923
Tonjum T., Klintz L., Bergan T., Baann J., Furuberg G., Cristea M., Petrini B., Hoffner S. (1996) Direct
detection of Mycobacterium tuberculosis in respiratory samples from patients in Scandinavia by
polymerase chain reaction. Clin.Microbiol.Infect. 2 (2):127-131
Bjelland S., Eide L., Time R. W., Stote R., Eftedal I., Volden G., Seeberg E. (1995) Oxidation of thymine
to 5-formyluracil in DNA: mechanisms of formation, structural implications, and base excision by human
cell free extracts. Biochemistry 34 (45):14758-14764
Bjoras M., Klungland A., Johansen R. F., Seeberg E. (1995) Purification and properties of the alkylation
repair DNA glycosylase encoded the MAG gene from Saccharomyces cerevisiae. Biochemistry 34
(14):4577-4582
Caugant D. A., Sandven P., Eng J., Jeque J. T., Tonjum T. (1995) Detection of rifampin resistance
among isolates of Mycobacterium tuberculosis from Mozambique. Microb.Drug Resist. 1 (4):321-326
Chiang S. L., Taylor R. K., Koomey M., Mekalanos J. J. (1995) Single amino acid substitutions in the Nterminus of Vibrio cholerae TcpA affect colonization, autoagglutination, and serum resistance.
Mol.Microbiol. 17 (6):1133-1142
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Drake S. L., Koomey M. (1995) The product of the pilQ gene is essential for the biogenesis of type IV pili
in Neisseria gonorrhoeae. Mol.Microbiol. 18 (5):975-986
Freitag N. E., Seifert H. S., Koomey M. (1995) Characterization of the pilF-pilD pilus-assembly locus of
Neisseria gonorrhoeae. Mol.Microbiol. 16 (3):575-586
Klungland A., Laake K., Hoff E., Seeberg E. (1995) Spectrum of mutations induced by methyl and ethyl
methanesulfonate at the hprt locus of normal and tag expressing Chinese hamster fibroblasts.
Carcinogenesis 16 (6):1281-1285
Kodjo A., Tonjum T., Richard Y., Bovre K. (1995) Moraxella caprae sp. nov., a new member of the
classical Moraxellae with very close affinity to Moraxella bovis. Int.J.Syst.Bacteriol. 45 (3):467-471
Koomey M. (1995) Prepilin-like molecules in type 4 pilus biogenesis: minor subunits, chaperones or
mediators of organelle translocation? Trends Microbiol. 3 (11):409-410
Lindahl T., Satoh M. S., Poirier G. G., Klungland A. (1995) Post-translational modification of poly(ADPribose) polymerase induced by DNA strand breaks. Trends Biochem.Sci. 20 (10):405-411
Seeberg E., Eide L., Bjoras M. (1995) The base excision repair pathway. Trends Biochem.Sci. 20
(10):391-397
Tonjum T., Bovre K., Juni E. (1995) Fastidious gram-negative bacteria: meeting the diagnostic challenge
with nucleic acid analysis. APMIS 103 (9):609-627
Tonjum T., Freitag N. E., Namork E., Koomey M. (1995) Identification and characterization of pilG, a
highly conserved pilus-assembly gene in pathogenic Neisseria. Mol.Microbiol. 16 (3):451-464
Bjelland S., Birkeland N. K., Benneche T., Volden G., Seeberg E. (1994) DNA glycosylase activities for
thymine residues oxidized in the methyl group are functions of the AlkA enzyme in Escherichia coli.
J.Biol.Chem. 269 (48):30489-30495
Boyum A., Lovhaug D., Seeberg E., Nordlie E. M. (1994) Identification of cytidine deaminase as inhibitor
of granulocyte-macrophage colony formation. Exp.Hematol. 22 (2):208-214
Brossay L., Paradis G., Fox R., Koomey M., Hebert J. (1994) Identification, localization, and distribution
of the PilT protein in Neisseria gonorrhoeae. Infect.Immun. 62 (6):2302-2308
Klungland A., Bjoras M., Hoff E., Seeberg E. (1994) Increased removal of 3-alkyladenine reduces the
frequencies of hprt mutations induced by methyl- and ethylmethanesulfonate in Chinese hamster
fibroblast cells. Nucleic Acids Res. 22 (9):1670-1674
Nordnes S., Krauss S., Johansen T. (1994) cDNA sequence of zebrafish (Brachydanio rerio) translation
elongation factor-1 alpha: molecular phylogeny of eukaryotes based on elongation factor-1 alpha protein
sequences. Biochim.Biophys.Acta 1219 (2):529-532
Skaar I., Gaustad P., Tonjum T., Holm B., Stenwig H. (1994) Streptococcus phocae sp. nov., a new
species isolated from clinical specimens from seals. Int.J.Syst.Bacteriol. 44 (4):646-650
Torp R., Danbolt N. C., Babaie E., Bjoras M., Seeberg E., Storm-Mathisen J., Ottersen O. P. (1994)
Differential expression of two glial glutamate transporters in the rat brain: an in situ hybridization study.
Eur.J.Neurosci. 6 (6):936-942
Albertson N. H., Koomey M. (1993) Molecular cloning and characterization of a proline iminopeptidase
gene from Neisseria gonorrhoeae. Mol.Microbiol. 9 (6):1203-1211
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Bjelland S., Bjoras M., Seeberg E. (1993) Excision of 3-methylguanine from alkylated DNA by 3methyladenine DNA glycosylase I of Escherichia coli. Nucleic Acids Res. 21 (9):2045-2049
Ericson J. U., Krauss S., Fjose A. (1993) Genomic sequence and embryonic expression of the zebrafish
homeobox gene hox-3.4. Int.J.Dev.Biol. 37 (2):263-272
Johansen T., Moens U., Holm T., Fjose A., Krauss S. (1993) Zebrafish pou[c]: a divergent POU family
gene ubiquitously expressed during embryogenesis. Nucleic Acids Res. 21 (3):475-483
Kanner B. I., Danbolt N., Pines G., Koepsell H., Seeberg E., Mathisen J. S. (1993) Structure and function
of the sodium and potassium-coupled glutamate transporter from rat brain. Biochem.Soc.Trans. 21
(1):59-61
Lauer P., Albertson N. H., Koomey M. (1993) Conservation of genes encoding components of a type IV
pilus assembly/two-step protein export pathway in Neisseria gonorrhoeae. Mol.Microbiol. 8 (2):357-368
Seeberg E. (1993) Physical and genetic mapping of the tag gene on the Escherichia coli chromosome.
J.Bacteriol. 175 (17):5733-5734
Tonjum T., Haas R. (1993) Identification of Actinobacillus actinomycetemcomitans by leukotoxin genespecific hybridization and polymerase chain reaction assays. J.Clin.Microbiol. 31 (7):1856-1859
Tonjum T., Weir S., Bovre K., Progulske-Fox A., Marrs C. F. (1993) Sequence divergence in two
tandemly located pilin genes of Eikenella corrodens. Infect.Immun. 61 (5):1909-1916
Fjose A., Njolstad P. R., Nornes S., Molven A., Krauss S. (1992) Structure and early embryonic
expression of the zebrafish engrailed-2 gene. Mech.Dev. 39 (1-2):51-62
Klungland A., Fairbairn L., Watson A. J., Margison G. P., Seeberg E. (1992) Expression of the E.coli 3methyladenine DNA glycosylase I gene in mammalian cells reduces the toxic and mutagenic effects of
methylating agents. EMBO J. 11 (12):4439-4444
Krauss S., Korzh V., Fjose A., Johansen T. (1992) Expression of four zebrafish wnt-related genes during
embryogenesis. Development 116 (1):249-259
Mikkola I., Fjose A., Kuwada J. Y., Wilson S., Guddal P. H., Krauss S. (1992) The paired domaincontaining nuclear factor pax[b] is expressed in specific commissural interneurons in zebrafish embryos.
J.Neurobiol. 23 (8):933-946
Pines G., Danbolt N. C., Bjoras M., Zhang Y., Bendahan A., Eide L., Koepsell H., Storm-Mathisen J.,
Seeberg E., Kanner B. I. (1992) Cloning and expression of a rat brain L-glutamate transporter. Nature
360 (6403):464-467
Tonjum T., Caugant D. A., Bovre K. (1992) Differentiation of Moraxella nonliquefaciens, M. lacunata, and
M. bovis by using multilocus enzyme electrophoresis and hybridization with pilin-specific DNA probes.
J.Clin.Microbiol. 30 (12):3099-3107
Zhang Q. Y., DeRyckere D., Lauer P., Koomey M. (1992) Gene conversion in Neisseria gonorrhoeae:
evidence for its role in pilus antigenic variation. Proc.Natl.Acad.Sci.U.S.A 89 (12):5366-5370
Borchsenius F., Bruun J. N., Tonjum T. (1991) Systemic meningococcal disease: the diagnosis on
admission to hospital. NIPH Ann. 14 (1):11-22
Degre M., Rollag H., Holter E., Tonjum T., Krajci Z., Bukholm G. (1991) [Diagnosis of cytomegalovirus
infections in hospitalized patients]. Tidsskr.Nor Laegeforen. 111 (28):3401-3404
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Koomey M., Bergstrom S., Blake M., Swanson J. (1991) Pilin expression and processing in pilus mutants
of Neisseria gonorrhoeae: critical role of Gly-1 in assembly. Mol.Microbiol. 5 (2):279-287
Krauss S., Johansen T., Korzh V., Fjose A. (1991) Expression of the zebrafish paired box gene pax[zf-b]
during early neurogenesis. Development 113 (4):1193-1206
Krauss S., Johansen T., Korzh V., Moens U., Ericson J. U., Fjose A. (1991) Zebrafish pax[zf-a]: a paired
box-containing gene expressed in the neural tube. EMBO J. 10 (12):3609-3619
Krauss S., Johansen T., Korzh V., Fjose A. (1991) Expression pattern of zebrafish pax genes suggests a
role in early brain regionalization. Nature 353 (6341):267-270
Patel P., Marrs C. F., Mattick J. S., Ruehl W. W., Taylor R. K., Koomey M. (1991) Shared antigenicity
and immunogenicity of type 4 pilins expressed by Pseudomonas aeruginosa, Moraxella bovis, Neisseria
gonorrhoaea, Dichelobacter nodosus, and Vibrio cholerae. Infect.Immun. 59 (12):4674-4676
Tonjum T., Marrs C. F., Rozsa F., Bovre K. (1991) The type 4 pilin of Moraxella nonliquefaciens exhibits
unique similarities with the pilins of Neisseria gonorrhoeae and Dichelobacter (Bacteroides) nodosus.
J.Gen.Microbiol. 137 ( Pt 10):2483-2490
Berdal K. G., Bjoras M., Bjelland S., Seeberg E. (1990) Cloning and expression in Escherichia coli of a
gene for an alkylbase DNA glycosylase from Saccharomyces cerevisiae; a homologue to the bacterial
alkA gene. EMBO J. 9 (13):4563-4568
Seeberg E., Fuchs R. P. (1990) Acetylaminofluorene bound to different guanines of the sequence GGCGCC- is excised with different efficiencies by the UvrABC excision nuclease in a pattern not
correlated to the potency of mutation induction. Proc.Natl.Acad.Sci.U.S.A 87 (1):191-194
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Ornung G., Ottersen O. P., Cullheim S., Ulfhake B. (1998) Distribution of glutamate-, glycine- and GABAimmunoreactive nerve terminals on dendrites in the cat spinal motor nucleus. Exp.Brain Res. 118
(4):517-532
Ottersen O. P., Takumi Y., Matsubara A., Landsend A. S., Laake J. H., Usami S. (1998) Molecular
organization of a type of peripheral glutamate synapse: the afferent synapses of hair cells in the inner ear.
Prog.Neurobiol. 54 (2):127-148
15
Pedarzani P., Krause M., Haug T., Storm J. F., Stuhmer W. (1998) Modulation of the Ca2+-activated K+
current sIAHP by a phosphatase-kinase balance under basal conditions in rat CA1 pyramidal neurons.
J.Neurophysiol. 79 (6):3252-3256
Ragnarson B., Ornung G., Ottersen O. P., Grant G., Ulfhake B. (1998) Ultrastructural detection of
neuronally transported choleragenoid by postembedding immunocytochemistry in freeze-substituted
Lowicryl HM20 embedded tissue. J.Neurosci.Methods 80 (2):129-136
Runden E., Seglen P. O., Haug F. M., Ottersen O. P., Wieloch T., Shamloo M., Laake J. H. (1998)
Regional selective neuronal degeneration after protein phosphatase inhibition in hippocampal slice
cultures: evidence for a MAP kinase-dependent mechanism. J.Neurosci. 18 (18):7296-7305
Takumi Y., Bergersen L., Landsend A. S., Rinvik E., Ottersen O. P. (1998) Synaptic arrangement of
glutamate receptors. Prog.Brain Res. 116:105-121
Takumi Y., Nagelhus E. A., Eidet J., Matsubara A., Usami S., Shinkawa H., Nielsen S., Ottersen O. P.
(1998) Select types of supporting cell in the inner ear express aquaporin-4 water channel protein.
Eur.J.Neurosci. 10 (12):3584-3595
Trotti D., Danbolt N. C., Volterra A. (1998) Glutamate transporters are oxidant-vulnerable: a molecular
link between oxidative and excitotoxic neurodegeneration? Trends Pharmacol.Sci. 19 (8):328-334
Wang Y. X., Wenthold R. J., Ottersen O. P., Petralia R. S. (1998) Endbulb synapses in the anteroventral
cochlear nucleus express a specific subset of AMPA-type glutamate receptor subunits. J.Neurosci. 18
(3):1148-1160
Weber J. R., Orstavik S., Torgersen K. M., Danbolt N. C., Berg S. F., Ryan J. C., Tasken K., Imboden J.
B., Vaage J. T. (1998) Molecular cloning of the cDNA encoding pp36, a tyrosine-phosphorylated adaptor
protein selectively expressed by T cells and natural killer cells. J.Exp.Med. 187 (7):1157-1161
Akbar M. T., Torp R., Danbolt N. C., Levy L. M., Meldrum B. S., Ottersen O. P. (1997) Expression of glial
glutamate transporters GLT-1 and GLAST is unchanged in the hippocampus in fully kindled rats.
Neuroscience 78 (2):351-359
Bjaalie J. G., Sudbo J., Brodal P. (1997) Corticopontine terminal fibres form small scale clusters and
large scale lamellae in the cat. Neuroreport 8 (7):1651-1655
Bjaalie J. G., Brodal P. (1997) Cat pontocerebellar network: numerical capacity and axonal collateral
branching of neurones in the pontine nuclei projecting to individual parafloccular folia. Neurosci.Res. 27
(3):199-210
Brodal P., Bjaalie J. G. (1997) Salient anatomic features of the cortico-ponto-cerebellar pathway.
Prog.Brain Res. 114:227-249
Gegelashvili G., Danbolt N. C., Schousboe A. (1997) Neuronal soluble factors differentially regulate the
expression of the GLT1 and GLAST glutamate transporters in cultured astroglia. J.Neurochem. 69
(6):2612-2615
Haverkamp S., Eldred W. D., Ottersen O. P., Pow D., Ammermuller J. (1997) Synaptic inputs to identified
color-coded amacrine and ganglion cells in the turtle retina. J.Comp Neurol. 389 (2):235-248
Johannsson E., Nagelhus E. A., McCullagh K. J., Sejersted O. M., Blackstad T. W., Bonen A., Ottersen
O. P. (1997) Cellular and subcellular expression of the monocarboxylate transporter MCT1 in rat heart. A
high-resolution immunogold analysis. Circ.Res. 80 (3):400-407
16
Landsend A. S., Amiry-Moghaddam M., Matsubara A., Bergersen L., Usami S., Wenthold R. J., Ottersen
O. P. (1997) Differential localization of delta glutamate receptors in the rat cerebellum: coexpression with
AMPA receptors in parallel fiber-spine synapses and absence from climbing fiber-spine synapses.
J.Neurosci. 17 (2):834-842
Lehre K. P., Davanger S., Danbolt N. C. (1997) Localization of the glutamate transporter protein GLAST
in rat retina. Brain Res. 744 (1):129-137
Nielsen S., Nagelhus E. A., Amiry-Moghaddam M., Bourque C., Agre P., Ottersen O. P. (1997)
Specialized membrane domains for water transport in glial cells: high-resolution immunogold
cytochemistry of aquaporin-4 in rat brain. J.Neurosci. 17 (1):171-180
Ottersen O. P., Chaudhry F. A., Danbolt N. C., Laake J. H., Nagelhus E. A., Storm-Mathisen J., Torp R.
(1997) Molecular organization of cerebellar glutamate synapses. Prog.Brain Res. 114:97-107
Ottersen O. P., Landsend A. S. (1997) Organization of glutamate receptors at the synapse.
Eur.J.Neurosci. 9 (11):2219-2224
Reichenberger I., Straka H., Ottersen O. P., Streit P., Gerrits N. M., Dieringer N. (1997) Distribution of
GABA, glycine, and glutamate immunoreactivities in the vestibular nuclear complex of the frog. J.Comp
Neurol. 377 (2):149-164
Shupliakov O., Ottersen O. P., Storm-Mathisen J., Brodin L. (1997) Glial and neuronal glutamine pools at
glutamatergic synapses with distinct properties. Neuroscience 77 (4):1201-1212
Takumi Y., Matsubara A., Danbolt N. C., Laake J. H., Storm-Mathisen J., Usami S., Shinkawa H.,
Ottersen O. P. (1997) Discrete cellular and subcellular localization of glutamine synthetase and the
glutamate transporter GLAST in the rat vestibular end organ. Neuroscience 79 (4):1137-1144
Torp R., Hoover F., Danbolt N. C., Storm-Mathisen J., Ottersen O. P. (1997) Differential distribution of
the glutamate transporters GLT1 and rEAAC1 in rat cerebral cortex and thalamus: an in situ hybridization
analysis. Anat.Embryol.(Berl) 195 (4):317-326
Trotti D., Rizzini B. L., Rossi D., Haugeto O., Racagni G., Danbolt N. C., Volterra A. (1997) Neuronal and
glial glutamate transporters possess an SH-based redox regulatory mechanism. Eur.J.Neurosci. 9
(6):1236-1243
Ullensvang K., Lehre K. P., Storm-Mathisen J., Danbolt N. C. (1997) Differential developmental
expression of the two rat brain glutamate transporter proteins GLAST and GLT. Eur.J.Neurosci. 9
(8):1646-1655
Amiry-Moghaddam M., Nagelhus E. A., Agre P., Nielsen S., Ottersen O. P. (1996) Taurine and water
channels are co-localized in renal tubule cells and other tissues. Immunocytochemical studies in rats.
Adv.Exp.Med.Biol. 403:165-171
Antal M., Petko M., Polgar E., Heizmann C. W., Storm-Mathisen J. (1996) Direct evidence of an
extensive GABAergic innervation of the spinal dorsal horn by fibres descending from the rostral
ventromedial medulla. Neuroscience 73 (2):509-518
Bjoras M., Gjesdal O., Erickson J. D., Torp R., Levy L. M., Ottersen O. P., Degree M., Storm-Mathisen J.,
Seeberg E., Danbolt N. C. (1996) Cloning and expression of a neuronal rat brain glutamate transporter.
Brain Res.Mol.Brain Res. 36 (1):163-168
Figenschou A., Hu G. Y., Storm J. F. (1996) Cholinergic modulation of the action potential in rat
hippocampal neurons. Eur.J.Neurosci. 8 (1):211-219
17
Gegelashvili G., Civenni G., Racagni G., Danbolt N. C., Schousboe I., Schousboe A. (1996) Glutamate
receptor agonists up-regulate glutamate transporter GLAST in astrocytes. Neuroreport 8 (1):261-265
Gundersen V., Ottersen O. P., Storm-Mathisen J. (1996) Selective excitatory amino acid uptake in
glutamatergic nerve terminals and in glia in the rat striatum: quantitative electron microscopic
immunocytochemistry of exogenous (D)-aspartate and endogenous glutamate and GABA.
Eur.J.Neurosci. 8 (4):758-765
Hackney C. M., Osen K. K., Ottersen O. P., Storm-Mathisen J., Manjaly G. (1996) Immunocytochemical
evidence that glutamate is a neurotransmitter in the cochlear nerve: a quantitative study in the guinea-pig
anteroventral cochlear nucleus. Eur.J.Neurosci. 8 (1):79-91
Haugeto O., Ullensvang K., Levy L. M., Chaudhry F. A., Honore T., Nielsen M., Lehre K. P., Danbolt N. C.
(1996) Brain glutamate transporter proteins form homomultimers. J.Biol.Chem. 271 (44):27715-27722
Langeveld C. H., Schepens E., Jongenelen C. A., Stoof J. C., Hjelle O. P., Ottersen O. P., Drukarch B.
(1996) Presence of glutathione immunoreactivity in cultured neurones and astrocytes. Neuroreport 7
(11):1833-1836
Matsubara A., Laake J. H., Davanger S., Usami S., Ottersen O. P. (1996) Organization of AMPA receptor
subunits at a glutamate synapse: a quantitative immunogold analysis of hair cell synapses in the rat
organ of Corti. J.Neurosci. 16 (14):4457-4467
Moore J. K., Osen K. K., Storm-Mathisen J., Ottersen O. P. (1996) gamma-Aminobutyric acid and glycine
in the baboon cochlear nuclei: an immunocytochemical colocalization study with reference to interspecies
differences in inhibitory systems. J.Comp Neurol. 369 (4):497-519
Nagelhus E. A., Lehmann A., Ottersen O. P. (1996) Neuronal and glial handling of glutamate and
glutamine during hypoosmotic stress: a biochemical and quantitative immunocytochemical analysis using
the rat cerebellum as a model. Neuroscience 72 (3):743-755
Ornung G., Shupliakov O., Linda H., Ottersen O. P., Storm-Mathisen J., Ulfhake B., Cullheim S. (1996)
Qualitative and quantitative analysis of glycine- and GABA-immunoreactive nerve terminals on
motoneuron cell bodies in the cat spinal cord: a postembedding electron microscopic study. J.Comp
Neurol. 365 (3):413-426
Ottersen O. P., Laake J. H., Reichelt W., Haug F. M., Torp R. (1996) Ischemic disruption of glutamate
homeostasis in brain: quantitative immunocytochemical analyses. J.Chem.Neuroanat. 12 (1):1-14
Pedarzani P., Storm J. F. (1996) Interaction between alpha- and beta-adrenergic receptor agonists
modulating the slow Ca(2+)-activated K+ current IAHP in hippocampal neurons. Eur.J.Neurosci. 8
(10):2098-2110
Pedarzani P., Storm J. F. (1996) Evidence that Ca/calmodulin-dependent protein kinase mediates the
modulation of the Ca2+-dependent K+ current, IAHP, by acetylcholine, but not by glutamate, in
hippocampal neurons. Pflugers Arch. 431 (5):723-728
Shupliakov O., Fagerstedt P., Ottersen O. P., Storm-Mathiesen J., Grillner S., Brodin L. (1996)
Immunocytochemical localization of glycine in the lamprey spinal cord with reference to GABAergic and
glutamatergic synapses: a light and electron microscopic study. Acta Biol.Hung. 47 (1-4):393-410
Trotti D., Rossi D., Gjesdal O., Levy L. M., Racagni G., Danbolt N. C., Volterra A. (1996) Peroxynitrite
inhibits glutamate transporter subtypes. J.Biol.Chem. 271 (11):5976-5979
18
Usami S., Hjelle O. P., Ottersen O. P. (1996) Differential cellular distribution of glutathione--an
endogenous antioxidant--in the guinea pig inner ear. Brain Res. 743 (1-2):337-340
Usami S., Ottersen O. P. (1996) Aspartate is enriched in sensory cells and subpopulations of nonneuronal cells in the guinea pig inner ear: a quantitative immunoelectron microscopic analysis. Brain
Res. 742 (1-2):43-49
Usami S., Ottersen O. P. (1996) Immunocytochemical localization of taurine in the inner ear.
Adv.Exp.Med.Biol. 403:361-368
Volterra A., Bezzi P., Rizzini B. L., Trotti D., Ullensvang K., Danbolt N. C., Racagni G. (1996) The
competitive transport inhibitor L-trans-pyrrolidine-2, 4-dicarboxylate triggers excitotoxicity in rat cortical
neuron-astrocyte co-cultures via glutamate release rather than uptake inhibition. Eur.J.Neurosci. 8
(9):2019-2028
Chaudhry F. A., Lehre K. P., van Lookeren Campagne M., Ottersen O. P., Danbolt N. C., Storm-Mathisen
J. (1995) Glutamate transporters in glial plasma membranes: highly differentiated localizations revealed
by quantitative ultrastructural immunocytochemistry. Neuron 15 (3):711-720
Ericson A. C., Blomqvist A., Craig A. D., Ottersen O. P., Broman J. (1995) Evidence for glutamate as
neurotransmitter in trigemino-and spinothalamic tract terminals in the nucleus submedius of cats.
Eur.J.Neurosci. 7 (2):305-317
Gundersen V., Shupliakov O., Brodin L., Ottersen O. P., Storm-Mathisen J. (1995) Quantification of
excitatory amino acid uptake at intact glutamatergic synapses by immunocytochemistry of exogenous Daspartate. J.Neurosci. 15 (6):4417-4428
Laake J. H., Slyngstad T. A., Haug F. M., Ottersen O. P. (1995) Glutamine from glial cells is essential for
the maintenance of the nerve terminal pool of glutamate: immunogold evidence from hippocampal slice
cultures. J.Neurochem. 65 (2):871-881
Leergaard T. B., Lakke E. A., Bjaalie J. G. (1995) Topographical organization in the early postnatal
corticopontine projection: a carbocyanine dye and 3-D computer reconstruction study in the rat. J.Comp
Neurol. 361 (1):77-94
Leergaard T. B., Bjaalie J. G. (1995) Semi-automatic data acquisition for quantitative neuroanatomy.
MicroTrace--computer programme for recording of the spatial distribution of neuronal populations.
Neurosci.Res. 22 (2):231-243
Lehre K. P., Levy L. M., Ottersen O. P., Storm-Mathisen J., Danbolt N. C. (1995) Differential expression
of two glial glutamate transporters in the rat brain: quantitative and immunocytochemical observations.
J.Neurosci. 15 (3 Pt 1):1835-1853
Levy L. M., Lehre K. P., Walaas S. I., Storm-Mathisen J., Danbolt N. C. (1995) Down-regulation of glial
glutamate transporters after glutamatergic denervation in the rat brain. Eur.J.Neurosci. 7 (10):2036-2041
Lundgren P., Mattsson M. O., Johansson L., Ottersen O. P., Sellstrom A. (1995) Morphological and
GABA-immunoreactive development of the embryonic chick telencephalon. Int.J.Dev.Neurosci. 13
(5):463-472
Malmierca M. S., Rees A., Le Beau F. E., Bjaalie J. G. (1995) Laminar organization of frequency-defined
local axons within and between the inferior colliculi of the guinea pig. J.Comp Neurol. 357 (1):124-144
19
Maxwell D. J., Ottersen O. P., Storm-Mathisen J. (1995) Synaptic organization of excitatory and inhibitory
boutons associated with spinal neurons which project through the dorsal columns of the cat. Brain Res.
676 (1):103-112
Ornung G., Ragnarson B., Grant G., Ottersen O. P., Storm-Mathisen J., Ulfhake B. (1995) Ia boutons to
CCN neurones and motoneurones are enriched with glutamate-like immunoreactivity. Neuroreport 6
(15):1975-1980
Osen K. K., Storm-Mathisen J., Ottersen O. P., Dihle B. (1995) Glutamate is concentrated in and
released from parallel fiber terminals in the dorsal cochlear nucleus: a quantitative immunocytochemical
analysis in guinea pig. J.Comp Neurol. 357 (3):482-500
Pedarzani P., Storm J. F. (1995) Protein kinase A-independent modulation of ion channels in the brain by
cyclic AMP. Proc.Natl.Acad.Sci.U.S.A 92 (25):11716-11720
Pedarzani P., Storm J. F. (1995) Dopamine modulates the slow Ca(2+)-activated K+ current IAHP via
cyclic AMP-dependent protein kinase in hippocampal neurons. J.Neurophysiol. 74 (6):2749-2753
Roberts R. C., McCarthy K. E., Du F., Ottersen O. P., Okuno E., Schwarcz R. (1995) 3Hydroxyanthranilic acid oxygenase-containing astrocytic processes surround glutamate-containing axon
terminals in the rat striatum. J.Neurosci. 15 (2):1150-1161
Rothe F., Brosz M., Storm-Mathisen J. (1995) Quantitative ultrastructural localization of glutamate
dehydrogenase in the rat cerebellar cortex. Neuroscience 64 (4):iii-xvi
Shupliakov O., Atwood H. L., Ottersen O. P., Storm-Mathisen J., Brodin L. (1995) Presynaptic glutamate
levels in tonic and phasic motor axons correlate with properties of synaptic release. J.Neurosci. 15
(11):7168-7180
Torp R., Lekieffre D., Levy L. M., Haug F. M., Danbolt N. C., Meldrum B. S., Ottersen O. P. (1995)
Reduced postischemic expression of a glial glutamate transporter, GLT1, in the rat hippocampus.
Exp.Brain Res. 103 (1):51-58
Trotti D., Volterra A., Lehre K. P., Rossi D., Gjesdal O., Racagni G., Danbolt N. C. (1995) Arachidonic
acid inhibits a purified and reconstituted glutamate transporter directly from the water phase and not via
the phospholipid membrane. J.Biol.Chem. 270 (17):9890-9895
Usami S., Ottersen O. P. (1995) Differential cellular distribution of glutamate and glutamine in the rat
vestibular endorgans: an immunocytochemical study. Brain Res. 676 (2):285-292
Usami S., Ottersen O. P. (1995) The localization of taurine-like immunoreactivity in the organ of Corti: a
semiquantitative, post-embedding immuno-electron microscopic analysis in the rat with some
observations in the guinea pig. Brain Res. 676 (2):277-284
Zafra F., Aragon C., Olivares L., Danbolt N. C., Gimenez C., Storm-Mathisen J. (1995) Glycine
transporters are differentially expressed among CNS cells. J.Neurosci. 15 (5 Pt 2):3952-3969
Amiry-Moghaddam M., Nagelhus E., Ottersen O. P. (1994) Light- and electronmicroscopic distribution of
taurine, an organic osmolyte, in rat renal tubule cells. Kidney Int. 45 (1):10-22
Danbolt N. C. (1994) The high affinity uptake system for excitatory amino acids in the brain.
Prog.Neurobiol. 44 (4):377-396
20
Danbolt N. C., Storm-Mathisen J., Ottersen O. P. (1994) Sodium/potassium-coupled glutamate
transporters, a "new" family of eukaryotic proteins: do they have "new" physiological roles and could they
be new targets for pharmacological intervention? Prog.Brain Res. 100:53-60
Davanger S., Torp R., Ottersen O. P. (1994) Co-localization of glutamate and homocysteic acid
immunoreactivities in human photoreceptor terminals. Neuroscience 63 (1):123-133
Davanger S., Hjelle O. P., Babaie E., Larsson L. I., Hougaard D., Storm-Mathisen J., Ottersen O. P.
(1994) Colocalization of gamma-aminobutyrate and gastrin in the rat antrum: an immunocytochemical
and in situ hybridization study. Gastroenterology 107 (1):137-148
Davanger S., Storm-Mathisen J., Ottersen O. P. (1994) Colocalization of glutamate and glycine in bipolar
cell terminals of the human retina. Exp.Brain Res. 98 (2):342-354
Didier A., Ottersen O. P., Storm-Mathisen J. (1994) Differential subcellular distribution of glutamate and
taurine in primary olfactory neurones. Neuroreport 6 (1):145-148
Hjelle O. P., Chaudhry F. A., Ottersen O. P. (1994) Antisera to glutathione: characterization and
immunocytochemical application to the rat cerebellum. Eur.J.Neurosci. 6 (5):793-804
Hvalby O., Hemmings H. C., Jr., Paulsen O., Czernik A. J., Nairn A. C., Godfraind J. M., Jensen V.,
Raastad M., Storm J. F., Andersen P., . (1994) Specificity of protein kinase inhibitor peptides and
induction of long-term potentiation. Proc.Natl.Acad.Sci.U.S.A 91 (11):4761-4765
Laerum H., Storm J. F. (1994) Hippocampal long-term potentiation is not accompanied by presynaptic
spike broadening, unlike synaptic potentiation by K+ channel blockers. Brain Res. 637 (1-2):349-355
Nagelhus E. A., Amiry-Moghaddam M., Lehmann A., Ottersen O. P. (1994) Taurine as an organic
osmolyte in the intact brain: immunocytochemical and biochemical studies. Adv.Exp.Med.Biol. 359:325334
Nikundiwe A. M., Bjaalie J. G., Brodal P. (1994) Lamellar organization of pontocerebellar neuronal
populations. A multi-tracer and 3-D computer reconstruction study in the cat. Eur.J.Neurosci. 6 (2):173186
Ornung G., Shupliakov O., Ottersen O. P., Storm-Mathisen J., Cullheim S. (1994) Immunohistochemical
evidence for coexistence of glycine and GABA in nerve terminals on cat spinal motoneurones: an
ultrastructural study. Neuroreport 5 (8):889-892
Rothe F., Brosz M., Storm-Mathisen J. (1994) Quantitative ultrastructural localization of glutamate
dehydrogenase in the rat cerebellar cortex. Neuroscience 62 (4):1133-1146
Shupliakov O., Brodin L., Srinivasan M., Grillner S., Cullheim S., Storm-Mathisen J., Ottersen O. P.
(1994) Extrasynaptic localization of taurine-like immunoreactivity in the lamprey spinal cord. J.Comp
Neurol. 347 (2):301-311
Torp R., Danbolt N. C., Babaie E., Bjoras M., Seeberg E., Storm-Mathisen J., Ottersen O. P. (1994)
Differential expression of two glial glutamate transporters in the rat brain: an in situ hybridization study.
Eur.J.Neurosci. 6 (6):936-942
Aas J. E., Berg-Johnsen J., Hegstad E., Laake J. H., Langmoen I. A., Ottersen O. P. (1993)
Redistribution of glutamate and glutamine in slices of human neocortex exposed to combined hypoxia
and glucose deprivation in vitro. J.Cereb.Blood Flow Metab 13 (3):503-515
21
Broman J., Anderson S., Ottersen O. P. (1993) Enrichment of glutamate-like immunoreactivity in primary
afferent terminals throughout the spinal cord dorsal horn. Eur.J.Neurosci. 5 (8):1050-1061
Casado M., Bendahan A., Zafra F., Danbolt N. C., Aragon C., Gimenez C., Kanner B. I. (1993)
Phosphorylation and modulation of brain glutamate transporters by protein kinase C. J.Biol.Chem. 268
(36):27313-27317
Castel M., Belenky M., Cohen S., Ottersen O. P., Storm-Mathisen J. (1993) Glutamate-like
immunoreactivity in retinal terminals of the mouse suprachiasmatic nucleus. Eur.J.Neurosci. 5 (4):368381
Danbolt C., Hansen T. W., Oyasoeter S., Storm-Mathisen J., Bratlid D. (1993) In vitro binding of
[3H]bilirubin to neurons in rat brain sections. Biol.Neonate 63 (1):35-39
Gundersen V., Danbolt N. C., Ottersen O. P., Storm-Mathisen J. (1993) Demonstration of
glutamate/aspartate uptake activity in nerve endings by use of antibodies recognizing exogenous Daspartate. Neuroscience 57 (1):97-111
Laake J. H., Torp R., Ottersen O. P. (1993) Ultrastructural immunocytochemical studies as a means of
distinguishing between transmitter and non-transmitter glutamate. Biochem.Soc.Trans. 21 (1):45-49
Levy L. M., Lehre K. P., Rolstad B., Danbolt N. C. (1993) A monoclonal antibody raised against an
[Na(+)+K+]coupled L-glutamate transporter purified from rat brain confirms glial cell localization. FEBS
Lett. 317 (1-2):79-84
Maxwell D. J., Christie W. M., Brown A. G., Ottersen O. P., Storm-Mathisen J. (1993) Identified hair
follicle afferent boutons in the spinal cord of the cat are enriched with L-glutamate-like immunoreactivity.
Brain Res. 606 (1):156-161
Nagelhus E. A., Lehmann A., Ottersen O. P. (1993) Neuronal-glial exchange of taurine during hypoosmotic stress: a combined immunocytochemical and biochemical analysis in rat cerebellar cortex.
Neuroscience 54 (3):615-631
Ottersen O. P. (1993) Neurotransmitters in the cerebellum. Rev.Neurol.(Paris) 149 (11):629-636
Pedarzani P., Storm J. F. (1993) PKA mediates the effects of monoamine transmitters on the K+ current
underlying the slow spike frequency adaptation in hippocampal neurons. Neuron 11 (6):1023-1035
Reichenberger I., Streit P., Ottersen O. P., Dieringer N. (1993) GABA- and glycine-like
immunoreactivities in the cerebellum of the frog. Neurosci.Lett. 154 (1-2):89-92
Reichenberger I., Streit P., Ottersen O. P., Dieringer N. (1993) Neurosci.Lett. 154 (1-2):89-92
Rinvik E., Ottersen O. P. (1993) Terminals of subthalamonigral fibres are enriched with glutamate-like
immunoreactivity: an electron microscopic, immunogold analysis in the cat. J.Chem.Neuroanat. 6 (1):1930
Shupliakov O., Ornung G., Brodin L., Ulfhake B., Ottersen O. P., Storm-Mathisen J., Cullheim S. (1993)
Immunocytochemical localization of amino acid neurotransmitter candidates in the ventral horn of the cat
spinal cord: a light microscopic study. Exp.Brain Res. 96 (3):404-418
Snyder G. L., Fisone G., Morino P., Gundersen V., Ottersen O. P., Hokfelt T., Greengard P. (1993)
Regulation by the neuropeptide cholecystokinin (CCK-8S) of protein phosphorylation in the neostriatum.
Proc.Natl.Acad.Sci.U.S.A 90 (23):11277-11281
22
Taublll E., Ottersen O. P., Gjerstad L. (1993) The progesterone metabolite 5 alpha-pregnan-3 alpha-ol20-one reduces K(+)-induced GABA and glutamate release from identified nerve terminals in rat
hippocampus: a semiquantitative immunocytochemical study. Brain Res. 623 (2):329-333
Torp R., Arvin B., Le Peillet E., Chapman A. G., Ottersen O. P., Meldrum B. S. (1993) Effect of ischaemia
and reperfusion on the extra- and intracellular distribution of glutamate, glutamine, aspartate and GABA in
the rat hippocampus, with a note on the effect of the sodium channel blocker BW1003C87. Exp.Brain
Res. 96 (3):365-376
Uematsu K., Shirasaki M., Storm-Mathisen J. (1993) J.Comp Neurol. 332 (1):59-68
Uematsu K., Shirasaki M., Storm-Mathisen J. (1993) GABA- and glycine-immunoreactive neurons in the
spinal cord of the carp, Cyprinus carpio. J.Comp Neurol. 332 (1):59-68
Waerhaug O., Ottersen O. P. (1993) Demonstration of glutamate-like immunoreactivity at rat
neuromuscular junctions by quantitative electron microscopic immunocytochemistry.
Anat.Embryol.(Berl) 188 (5):501-513
Zhang N., Ottersen O. P. (1993) In search of the identity of the cerebellar climbing fiber transmitter:
immunocytochemical studies in rats. Can.J.Neurol.Sci. 20 Suppl 3:S36-S42
Aas J. E., Laake J. H., Brodal P., Ottersen O. P. (1992) Immunocytochemical evidence for in vitro
release of glutamate and GABA from separate nerve terminal populations in the rat pontine nuclei.
Exp.Brain Res. 89 (3):540-548
Antal M., Sholomenko G. N., Moschovakis A. K., Storm-Mathisen J., Heizmann C. W., Hunziker W.
(1992) The termination pattern and postsynaptic targets of rubrospinal fibers in the rat spinal cord: a light
and electron microscopic study. J.Comp Neurol. 325 (1):22-37
Brodal P., Bjaalie J. G. (1992) Organization of the pontine nuclei. Neurosci.Res. 13 (2):83-118
Broman J., Ottersen O. P. (1992) Cervicothalamic tract terminals are enriched in glutamate-like
immunoreactivity: an electron microscopic double-labeling study in the cat. J.Neurosci. 12 (1):204-221
Danbolt N. C., Storm-Mathisen J., Kanner B. I. (1992) An [Na+ + K+]coupled L-glutamate transporter
purified from rat brain is located in glial cell processes. Neuroscience 51 (2):295-310
Hees B., Danbolt N. C., Kanner B. I., Haase W., Heitmann K., Koepsell H. (1992) A monoclonal antibody
against a Na(+)-L-glutamate cotransporter from rat brain. J.Biol.Chem. 267 (32):23275-23281
Hu G. Y., Storm J. F. (1992) 2-Amino-3-phosphonopropionate fails to block postsynaptic effects of
metabotropic glutamate receptors in rat hippocampal neurones. Acta Physiol.Scand. 145 (2):187-191
Kolston J., Osen K. K., Hackney C. M., Ottersen O. P., Storm-Mathisen J. (1992) An atlas of glycine- and
GABA-like immunoreactivity and colocalization in the cochlear nuclear complex of the guinea pig.
Anat.Embryol.(Berl) 186 (5):443-465
Maxwell D. J., Christie W. M., Brown A. G., Ottersen O. P., Storm-Mathisen J. (1992) Direct observations
of synapses between L-glutamate-immunoreactive boutons and identified spinocervical tract neurones in
the spinal cord of the cat. J.Comp Neurol. 326 (4):485-500
McNulty J. A., Kus L., Ottersen O. P. (1992) Immunocytochemical and circadian biochemical analysis of
neuroactive amino acids in the pineal gland of the rat: effect of superior cervical ganglionectomy. Cell
Tissue Res. 269 (3):515-523
23
Ottersen O. P., Zhang N., Walberg F. (1992) Metabolic compartmentation of glutamate and glutamine:
morphological evidence obtained by quantitative immunocytochemistry in rat cerebellum. Neuroscience
46 (3):519-534
Pines G., Danbolt N. C., Bjoras M., Zhang Y., Bendahan A., Eide L., Koepsell H., Storm-Mathisen J.,
Seeberg E., Kanner B. I. (1992) Cloning and expression of a rat brain L-glutamate transporter. Nature
360 (6403):464-467
Rauen T., Jeserich G., Danbolt N. C., Kanner B. I. (1992) Comparative analysis of sodium-dependent Lglutamate transport of synaptosomal and astroglial membrane vesicles from mouse cortex. FEBS Lett.
312 (1):15-20
Shupliakov O., Brodin L., Cullheim S., Ottersen O. P., Storm-Mathisen J. (1992) Immunogold
quantification of glutamate in two types of excitatory synapse with different firing patterns. J.Neurosci. 12
(10):3789-3803
Storm-Mathisen J., Danbolt N. C., Rothe F., Torp R., Zhang N., Aas J. E., Kanner B. I., Langmoen I.,
Ottersen O. P. (1992) Ultrastructural immunocytochemical observations on the localization, metabolism
and transport of glutamate in normal and ischemic brain tissue. Prog.Brain Res. 94:225-241
Torp R., Haug F. M., Tonder N., Zimmer J., Ottersen O. P. (1992) Neuroactive amino acids in
organotypic slice cultures of the rat hippocampus: an immunocytochemical study of the distribution of
GABA, glutamate, glutamine and taurine. Neuroscience 46 (4):807-823
Usami S., Osen K. K., Zhang N., Ottersen O. P. (1992) Distribution of glutamate-like and glutamine-like
immunoreactivities in the rat organ of Corti: a light microscopic and semiquantitative electron microscopic
analysis with a note on the localization of aspartate. Exp.Brain Res. 91 (1):1-11
Walberg F., Ottersen O. P. (1992) Neuroactive amino acids in the area postrema. An
immunocytochemical investigation in rat with some observations in cat and monkey (Macaca fascicularis).
Anat.Embryol.(Berl) 185 (6):529-545
Zhang N., Ottersen O. P. (1992) Differential cellular distribution of two sulphur-containing amino acids in
rat cerebellum. An immunocytochemical investigation using antisera to taurine and homocysteic acid.
Exp.Brain Res. 90 (1):11-20
Bjaalie J. G., Diggle P. J., Nikundiwe A., Karagulle T., Brodal P. (1991) Spatial segregation between
populations of ponto-cerebellar neurons: statistical analysis of multivariate spatial interactions. Anat.Rec.
231 (4):510-523
Brodal P., Bjaalie J. G., Aas J. E. (1991) Organization of cingulo-ponto-cerebellar connections in the cat.
Anat.Embryol.(Berl) 184 (3):245-254
Clarke J. D., Holder N., Soffe S. R., Storm-Mathisen J. (1991) Neuroanatomical and functional analysis
of neural tube formation in notochordless Xenopus embryos; laterality of the ventral spinal cord is lost.
Development 112 (2):499-516
Davanger S., Ottersen O. P., Storm-Mathisen J. (1991) Glutamate, GABA, and glycine in the human
retina: an immunocytochemical investigation. J.Comp Neurol. 311 (4):483-494
Hu G. Y., Storm J. F. (1991) Excitatory amino acids acting on metabotropic glutamate receptors broaden
the action potential in hippocampal neurons. Brain Res. 568 (1-2):339-344
24
Ji Z. Q., Aas J. E., Laake J., Walberg F., Ottersen O. P. (1991) An electron microscopic, immunogold
analysis of glutamate and glutamine in terminals of rat spinocerebellar fibers. J.Comp Neurol. 307
(2):296-310
Lehmann A., Carlstrom C., Nagelhus E. A., Ottersen O. P. (1991) Elevation of taurine in hippocampal
extracellular fluid and cerebrospinal fluid of acutely hypoosmotic rats: contribution by influx from blood?
J.Neurochem. 56 (2):690-697
Osen K. K., Lopez D. E., Slyngstad T. A., Ottersen O. P., Storm-Mathisen J. (1991) GABA-like and
glycine-like immunoreactivities of the cochlear root nucleus in rat. J.Neurocytol. 20 (1):17-25
Torp R., Andine P., Hagberg H., Karagulle T., Blackstad T. W., Ottersen O. P. (1991) Cellular and
subcellular redistribution of glutamate-, glutamine- and taurine-like immunoreactivities during forebrain
ischemia: a semiquantitative electron microscopic study in rat hippocampus. Neuroscience 41 (2-3):433447
Watson A. H., Storm-Mathisen J., Ottersen O. P. (1991) GABA and glutamate-like immunoreactivity in
processes presynaptic to afferents from hair plates on the proximal joints of the locust leg. J.Neurocytol.
20 (10):796-809
Zhang N. H., Laake J., Nagelhus E., Storm-Mathisen J., Ottersen O. P. (1991) Distribution of glutaminelike immunoreactivity in the cerebellum of rat and baboon (Papio anubis) with reference to the issue of
metabolic compartmentation. Anat.Embryol.(Berl) 184 (3):213-223
Aas J. E., Brodal P., Baughman R. W., Storm-Mathisen J. (1990) Projections to the pontine nuclei from
choline acetyltransferase-like immunoreactive neurons in the brainstem of the cat. J.Comp Neurol. 300
(2):183-195
Andersen P., Raastad M., Storm J. F. (1990) Excitatory synaptic integration in hippocampal pyramids
and dentate granule cells. Cold Spring Harb.Symp.Quant.Biol. 55:81-86
Bjaalie J. G., Diggle P. J. (1990) Statistical analysis of corticopontine neuron distribution in visual areas
17, 18, and 19 of the cat. J.Comp Neurol. 295 (1):15-32
Blackstad T. W., Karagulle T., Ottersen O. P. (1990) MORFOREL, a computer program for twodimensional analysis of micrographs of biological specimens, with emphasis on immunogold
preparations. Comput.Biol.Med. 20 (1):15-34
Bramham C. R., Torp R., Zhang N., Storm-Mathisen J., Ottersen O. P. (1990) Distribution of glutamatelike immunoreactivity in excitatory hippocampal pathways: a semiquantitative electron microscopic study
in rats. Neuroscience 39 (2):405-417
Brodin L., Dale N., Christenson J., Storm-Mathisen J., Hokfelt T., Grillner S. (1990) Three types of
GABA-immunoreactive cells in the lamprey spinal cord. Brain Res. 508 (1):172-175
Broman J., Westman J., Ottersen O. P. (1990) Ascending afferents to the lateral cervical nucleus are
enriched in glutamate-like immunoreactivity: a combined anterograde transport-immunogold study in the
cat. Brain Res. 520 (1-2):178-191
Danbolt N. C., Pines G., Kanner B. I. (1990) Purification and reconstitution of the sodium- and
potassium-coupled glutamate transport glycoprotein from rat brain. Biochemistry 29 (28):6734-6740
Madsen S., Ottersen O. P., Storm-Mathisen J., Sturman J. A. (1990) Immunocytochemical localization of
taurine: methodological aspects. Prog.Clin.Biol.Res. 351:37-44
25
Maxwell D. J., Christie W. M., Short A. D., Storm-Mathisen J., Ottersen O. P. (1990) Central boutons of
glomeruli in the spinal cord of the cat are enriched with L-glutamate-like immunoreactivity. Neuroscience
36 (1):83-104
Maxwell D. J., Christie W. M., Ottersen O. P., Storm-Mathisen J. (1990) Terminals of group Ia primary
afferent fibres in Clarke's column are enriched with L-glutamate-like immunoreactivity. Brain Res. 510
(2):346-350
Ottersen O. P., Laake J. H., Storm-Mathisen J. (1990) Demonstration of a releasable pool of glutamate in
cerebellar mossy and parallel fibre terminals by means of light and electron microscopic
immunocytochemistry. Arch.Ital.Biol. 128 (2-4):111-125
Ottersen O. P., Storm-Mathisen J., Bramham C., Torp R., Laake J., Gundersen V. (1990) A quantitative
electron microscopic immunocytochemical study of the distribution and synaptic handling of glutamate in
rat hippocampus. Prog.Brain Res. 83:99-114
Radian R., Ottersen O. P., Storm-Mathisen J., Castel M., Kanner B. I. (1990) Immunocytochemical
localization of the GABA transporter in rat brain. J.Neurosci. 10 (4):1319-1330
Storm-Mathisen J., Ottersen O. P. (1990) Immunocytochemistry of glutamate at the synaptic level.
J.Histochem.Cytochem. 38 (12):1733-1743
Storm J. F. (1990) Potassium currents in hippocampal pyramidal cells. Prog.Brain Res. 83:161-187
Walberg F., Ottersen O. P., Rinvik E. (1990) GABA, glycine, aspartate, glutamate and taurine in the
vestibular nuclei: an immunocytochemical investigation in the cat. Exp.Brain Res. 79 (3):547-563
Zhang N., Walberg F., Laake J. H., Meldrum B. S., Ottersen O. P. (1990) Aspartate-like and glutamatelike immunoreactivities in the inferior olive and climbing fibre system: a light microscopic and
semiquantitative electron microscopic study in rat and baboon (Papio anubis). Neuroscience 38 (1):6180
Aas J. E., Ottersen O. P., Brodal P. (1989) Profiles enriched in GABA-like immunoreactivity participate in
serial synapses in the pontine nuclei of baboon (Papio anubis). Exp.Brain Res. 78 (3):641-645
Bjaalie J. G., Brodal P. (1989) Visual pathways to the cerebellum: segregation in the pontine nuclei of
terminal fields from different visual cortical areas in the cat. Neuroscience 29 (1):95-107
Bjaalie J. G. (1989) The corticopontine projection from area 20 and surrounding areas in the cat: terminal
fields and distribution of cells of origin as compared to other visual cortical areas. Neuroscience 29
(1):81-93
Davanger S., Ottersen O. P., Storm-Mathisen J. (1989) GABA-immunoreactive cells in the rat
gastrointestinal epithelium. Anat.Embryol.(Berl) 179 (3):221-226
Furness J. B., Trussell D. C., Pompolo S., Bornstein J. C., Maley B. E., Storm-Mathisen J. (1989) Shapes
and projections of neurons with immunoreactivity for gamma-aminobutyric acid in the guinea-pig small
intestine. Cell Tissue Res. 256 (2):293-301
Gholson A. R., Storm J. F., Jayanty R. K., Fuerst R. G., Logan T. J., Midgett M. R. (1989) Evaluation of
canisters for measuring emissions of volatile organic air pollutants from hazardous waste incineration.
JAPCA. 39 (9):1210-1217
Ottersen O. P., Torp R., Storm-Mathisen J. (1989) [New aspects of the pathogenesis of ischemic brain
damage. Possible involvement of excitatory amino acids]. Tidsskr.Nor Laegeforen. 109 (26):2674-2677
26
Ottersen O. P. (1989) Postembedding immunogold labelling of fixed glutamate: an electron microscopic
analysis of the relationship between gold particle density and antigen concentration. J.Chem.Neuroanat.
2 (1):57-66
Ottersen O. P. (1989) Quantitative electron microscopic immunocytochemistry of neuroactive amino
acids. Anat.Embryol.(Berl) 180 (1):1-15
Overby S. E., Bjaalie J. G., Brodal P. (1989) Uneven densities of corticopontine neurons in the
somatosensory cortex: a quantitative experimental study in the cat. Exp.Brain Res. 77 (3):653-665
Storm J. F. (1989) An after-hyperpolarization of medium duration in rat hippocampal pyramidal cells.
J.Physiol 409:171-190
Walberg F., Ottersen O. P. (1989) Demonstration of GABA immunoreactive cells in the inferior olive of
baboons (Papio papio and Papio anubis). Neurosci.Lett. 101 (2):149-155
Yingcharoen K., Rinvik E., Storm-Mathisen J., Ottersen O. P. (1989) GABA, glycine, glutamate, aspartate
and taurine in the perihypoglossal nuclei: an immunocytochemical investigation in the cat with particular
reference to the issue of amino acid colocalization. Exp.Brain Res. 78 (2):345-357
Bicker G., Schafer S., Ottersen O. P., Storm-Mathisen J. (1988) Glutamate-like immunoreactivity in
identified neuronal populations of insect nervous systems. J.Neurosci. 8 (6):2108-2122
Blackstad T. W., Bjaalie J. G. (1988) Computer programs for neuroanatomy: three-dimensional
reconstruction and analysis of populations of cortical neurons and other bodies with a laminar distribution.
Comput.Biol.Med. 18 (5):321-340
Brodal P., Mihailoff G., Border B., Ottersen O. P., Storm-Mathisen J. (1988) GABA-containing neurons in
the pontine nuclei of rat, cat and monkey. An immunocytochemical study. Neuroscience 25 (1):27-45
Ehinger B., Ottersen O. P., Storm-Mathisen J., Dowling J. E. (1988) Bipolar cells in the turtle retina are
strongly immunoreactive for glutamate. Proc.Natl.Acad.Sci.U.S.A 85 (21):8321-8325
Kasa P., Joo F., Dobo E., Wenthold R. J., Ottersen O. P., Storm-Mathisen J., Wolff J. R. (1988)
Heterogeneous distribution of GABA-immunoreactive nerve fibers and axon terminals in the superior
cervical ganglion of adult rat. Neuroscience 26 (2):635-644
Ottersen O. P., Madsen S., Storm-Mathisen J., Somogyi P., Scopsi L., Larsson L. I. (1988)
Immunocytochemical evidence suggests that taurine is colocalized with GABA in the Purkinje cell
terminals, but that the stellate cell terminals predominantly contain GABA: a light- and
electronmicroscopic study of the rat cerebellum. Exp.Brain Res. 72 (2):407-416
Ottersen O. P., Storm-Mathisen J., Somogyi P. (1988) Colocalization of glycine-like and GABA-like
immunoreactivities in Golgi cell terminals in the rat cerebellum: a postembedding light and electron
microscopic study. Brain Res. 450 (1-2):342-353
Ottersen O. P. (1988) Quantitative assessment of taurine-like immunoreactivity in different cell types and
processes in rat cerebellum: an electronmicroscopic study based on a postembedding immunogold
labelling procedure. Anat.Embryol.(Berl) 178 (5):407-421
Roberts A., Dale N., Ottersen O. P., Storm-Mathisen J. (1988) Development and characterization of
commissural interneurones in the spinal cord of Xenopus laevis embryos revealed by antibodies to
glycine. Development 103 (3):447-461
27
Schafer S., Bicker G., Ottersen O. P., Storm-Mathisen J. (1988) Taurine-like immunoreactivity in the
brain of the honeybee. J.Comp Neurol. 268 (1):60-70
Storm J. F. (1988) Temporal integration by a slowly inactivating K+ current in hippocampal neurons.
Nature 336 (6197):379-381
Dale N., Roberts A., Ottersen O. P., Storm-Mathisen J. (1987) The morphology and distribution of
'Kolmer-Agduhr cells', a class of cerebrospinal-fluid-contacting neurons revealed in the frog embryo spinal
cord by GABA immunocytochemistry. Proc.R.Soc.Lond B Biol.Sci. 232 (1267):193-203
Dale N., Roberts A., Ottersen O. P., Storm-Mathisen J. (1987) The development of a population of spinal
cord neurons and their axonal projections revealed by GABA immunocytochemistry in frog embryos.
Proc.R.Soc.Lond B Biol.Sci. 232 (1267):205-215
Davanger S., Ottersen O. P., Storm-Mathisen J. (1987) Immunocytochemical localization of GABA in cat
myenteric plexus. Neurosci.Lett. 73 (1):27-32
Kosaka K., Hama K., Nagatsu I., Wu J. Y., Ottersen O. P., Storm-Mathisen J., Kosaka T. (1987)
Postnatal development of neurons containing both catecholaminergic and GABAergic traits in the rat
main olfactory bulb. Brain Res. 403 (2):355-360
Kosaka T., Kosaka K., Hataguchi Y., Nagatsu I., Wu J. Y., Ottersen O. P., Storm-Mathisen J., Hama K.
(1987) Catecholaminergic neurons containing GABA-like and/or glutamic acid decarboxylase-like
immunoreactivities in various brain regions of the rat. Exp.Brain Res. 66 (1):191-210
Madsen S., Ottersen O. P., Storm-Mathisen J. (1987) Immunocytochemical demonstration of taurine.
Adv.Exp.Med.Biol. 217:275-284
Meldrum B. S., Swan J. H., Ottersen O. P., Storm-Mathisen J. (1987) Redistribution of transmitter amino
acids in rat hippocampus and cerebellum during seizures induced by L-allylglycine and bicuculline: an
immunocytochemical study with antisera against conjugated GABA, glutamate and aspartate.
Neuroscience 22 (1):17-27
Ottersen O. P., Davanger S., Storm-Mathisen J. (1987) Glycine-like immunoreactivity in the cerebellum
of rat and Senegalese baboon, Papio papio: a comparison with the distribution of GABA-like
immunoreactivity and with [3H]glycine and [3H]GABA uptake. Exp.Brain Res. 66 (1):211-221
Ottersen O. P. (1987) Postembedding light- and electron microscopic immunocytochemistry of amino
acids: description of a new model system allowing identical conditions for specificity testing and tissue
processing. Exp.Brain Res. 69 (1):167-174
Rinvik E., Ottersen O. P., Storm-Mathisen J. (1987) Gamma-aminobutyrate-like immunoreactivity in the
thalamus of the cat. Neuroscience 21 (3):781-805
Roberts A., Dale N., Ottersen O. P., Storm-Mathisen J. (1987) The early development of neurons with
GABA immunoreactivity in the CNS of Xenopus laevis embryos. J.Comp Neurol. 261 (3):435-449
Storm-Mathisen J., Ottersen O. P. (1987) Tracing of neurons with glutamate or gamma-aminobutyrate as
putative transmitters. Biochem.Soc.Trans. 15 (2):210-213
Storm J. F. (1987) Action potential repolarization and a fast after-hyperpolarization in rat hippocampal
pyramidal cells. J.Physiol 385:733-759
Storm J. F. (1987) Intracellular injection of a Ca2+ chelator inhibits spike repolarization in hippocampal
neurons. Brain Res. 435 (1-2):387-392
28
Storm J. F. (1987) Phorbol esters broaden the action potential in CA1 hippocampal pyramidal cells.
Neurosci.Lett. 75 (1):71-74
Agardh E., Bruun A., Ehinger B., Storm-Mathisen J. (1986) GABA immunoreactivity in the retina. Invest
Ophthalmol.Vis.Sci. 27 (5):674-678
Bjaalie J. G. (1986) Distribution of corticopontine neurons in visual areas of the middle suprasylvian
sulcus: quantitative studies in the cat. Neuroscience 18 (4):1013-1033
Dale N., Ottersen O. P., Roberts A., Storm-Mathisen J. (1986) Inhibitory neurones of a motor pattern
generator in Xenopus revealed by antibodies to glycine. Nature 324 (6094):255-257
Danbolt N. C., Storm-Mathisen J. (1986) Inhibition by K+ of Na+-dependent D-aspartate uptake into brain
membrane saccules. J.Neurochem. 47 (3):825-830
Danbolt N. C., Storm-Mathisen J. (1986) Na+-dependent "binding" of D-aspartate in brain membranes is
largely due to uptake into membrane-bounded saccules. J.Neurochem. 47 (3):819-824
Fischer B. O., Ottersen O. P., Storm-Mathisen J. (1986) Implantation of D-[3H]aspartate loaded gel
particles permits restricted uptake sites for transmitter-selective axonal transport. Exp.Brain Res. 63
(3):620-626
Madsen S., Ottersen O. P., Storm-Mathisen J., Hokland B. (1986) [Taurine--an interesting amino acid].
Tidsskr.Nor Laegeforen. 106 (4):320-322
Orensanz L. M., Fernandez I., Martin del Rio, Storm-Mathisen J. (1986) Gamma-aminobutyric acid in the
rat oviduct. Adv.Biochem.Psychopharmacol. 42:265-274
Ottersen O. P., Storm-Mathisen J., Madsen S., Skumlien S., Stromhaug J. (1986) Evaluation of the
immunocytochemical method for amino acids. Med.Biol. 64 (2-3):147-158
Ottersen O. P., Storm-Mathisen J. (1986) Excitatory amino acid pathways in the brain.
Adv.Exp.Med.Biol. 203:263-284
Ottersen O. P., Fischer B. O., Rinvik E., Storm-Mathisen J. (1986) Putative amino acid transmitters in the
amygdala. Adv.Exp.Med.Biol. 203:53-66
Somogyi P., Halasy K., Somogyi J., Storm-Mathisen J., Ottersen O. P. (1986) Quantification of
immunogold labelling reveals enrichment of glutamate in mossy and parallel fibre terminals in cat
cerebellum. Neuroscience 19 (4):1045-1050
Storm-Mathisen J., Ottersen O. P., Fu-Long T., Gundersen V., Laake J. H., Nordbo G. (1986)
Metabolism and transport of amino acids studied by immunocytochemistry. Med.Biol. 64 (2-3):127-132
Bjaalie J. G. (1985) Distribution in areas 18 and 19 of neurons projecting to the pontine nuclei: a
quantitative study in the cat with retrograde transport of HRP-WGA. Exp.Brain Res. 57 (3):585-597
Madsen S., Ottersen O. P., Storm-Mathisen J. (1985) Immunocytochemical visualization of taurine:
neuronal localization in the rat cerebellum. Neurosci.Lett. 60 (3):255-260
Ottersen O. P., Madsen S., Meldrum B. S., Storm-Mathisen J. (1985) Taurine in the hippocampal
formation of the Senegalese baboon, Papio papio: an immunocytochemical study with an antiserum
against conjugated taurine. Exp.Brain Res. 59 (3):457-462
29
Ottersen O. P., Storm-Mathisen J. (1985) Different neuronal localization of aspartate-like and glutamatelike immunoreactivities in the hippocampus of rat, guinea-pig and Senegalese baboon (Papio papio), with
a note on the distribution of gamma-aminobutyrate. Neuroscience 16 (3):589-606
Ottersen O. P., Storm-Mathisen J. (1984) Glutamate- and GABA-containing neurons in the mouse and
rat brain, as demonstrated with a new immunocytochemical technique. J.Comp Neurol. 229 (3):374-392
Ottersen O. P., Storm-Mathisen J. (1984) GABA-containing neurons in the thalamus and pretectum of
the rodent. An immunocytochemical study. Anat.Embryol.(Berl) 170 (2):197-207
Taxt T., Storm-Mathisen J. (1984) Uptake of D-aspartate and L-glutamate in excitatory axon terminals in
hippocampus: autoradiographic and biochemical comparison with gamma-aminobutyrate and other amino
acids in normal rats and in rats with lesions. Neuroscience 11 (1):79-100
Wolf G., Schunzel G., Storm-Mathisen J. (1984) Lesions of Schaffer's collaterals in the rat hippocampus
affecting glutamate dehydrogenase and succinate dehydrogenase activity in the stratum radiatum of CA
1. A study with special reference to the glutamate transmitter metabolism. J.Hirnforsch. 25 (3):249-253
Bjaalie J. G., Brodal P. (1983) Distribution in area 17 of neurons projecting to the pontine nuclei: a
quantitative study in the cat with retrograde transport of HRP-WGA. J.Comp Neurol. 221 (3):289-303
Brodal P., Dietrichs E., Bjaalie J. G., Nordby T., Walberg F. (1983) Is lectin-coupled horseradish
peroxidase taken up and transported by undamaged as well as by damaged fibers in the central nervous
system? Brain Res. 278 (1-2):1-9
Dietrichs E., Bjaalie J. G., Brodal P. (1983) Do pontocerebellar fibers send collaterals to the cerebellar
nuclei? Brain Res. 259 (1):127-131
Gjone E., Storm-Mathisen J., Prydz H. (1983) [Jahre prize winners of the year]. Tidsskr.Nor
Laegeforen. 103 (15):1279-1281
Ottersen O. P., Fischer B. O., Storm-Mathisen J. (1983) Retrograde transport of D-[3H]aspartate in
thalamocortical neurones. Neurosci.Lett. 42 (1):19-24
Storm-Mathisen J., Leknes A. K., Bore A. T., Vaaland J. L., Edminson P., Haug F. M., Ottersen O. P.
(1983) First visualization of glutamate and GABA in neurones by immunocytochemistry. Nature 301
(5900):517-520
Thangnipon W., Taxt T., Brodal P., Storm-Mathisen J. (1983) The corticopontine projection: axotomyinduced loss of high affinity L-glutamate and D-aspartate uptake, but not of gamma-aminobutyrate
uptake, glutamate decarboxylase or choline acetyltransferase, in the pontine nuclei. Neuroscience 8
(3):449-457
Tremblay E., Ottersen O. P., Rovira C., Ben Ari Y. (1983) Intra-amygdaloid injections of kainic acid:
regional metabolic changes and their relation to the pathological alterations. Neuroscience 8 (2):299-315
Ottersen O. P. (1982) Connections of the amygdala of the rat. IV: Corticoamygdaloid and
intraamygdaloid connections as studied with axonal transport of horseradish peroxidase. J.Comp Neurol.
205 (1):30-48
Fonnum F., Storm-Mathisen J., Divac I. (1981) Biochemical evidence for glutamate as neurotransmitter
in corticostriatal and corticothalamic fibres in rat brain. Neuroscience 6 (5):863-873
Ottersen O. P. (1981) Afferent connections to the amygdaloid complex of the rat with some observations
in the cat. III. Afferents from the lower brain stem. J.Comp Neurol. 202 (3):335-356
30
Storm-Mathisen J., Wold J. E. (1981) In vivo high-affinity uptake and axonal transport of D-[2,33H]aspartate in excitatory neurons. Brain Res. 230 (1-2):427-433
Storm-Mathisen J. (1981) Glutamate in hippocampal pathways. Adv.Biochem.Psychopharmacol.
27:43-55
Thangnipon W., Storm-Mathisen J. (1981) K+-evoked Caa+-dependent release of D-[3H]aspartate from
terminals of the cortico-pontine pathway. Neurosci.Lett. 23 (2):181-186
Ben Ari Y., Tremblay E., Ottersen O. P. (1980) Injections of kainic acid into the amygdaloid complex of
the rat: an electrographic, clinical and histological study in relation to the pathology of epilepsy.
Neuroscience 5 (3):515-528
Ben Ari Y., Tremblay E., Ottersen O. P., Meldrum B. S. (1980) The role of epileptic activity in
hippocampal and "remote" cerebral lesions induced by kainic acid. Brain Res. 191 (1):79-97
Ottersen O. P. (1980) Afferent connections to the amygdaloid complex of the rat and cat: II. Afferents
from the hypothalamus and the basal telencephalon. J.Comp Neurol. 194 (1):267-289
Ben Ari Y., Tremblay E., Ottersen O. P., Naquet R. (1979) Evidence suggesting secondary epileptogenic
lesion after kainic acid: pre treatment with diazepam reduces distant but not local brain damage. Brain
Res. 165 (2):362-365
Ben Ari Y., Tremblay E., Ottersen O. P. (1979) [Primary and secondary cerebral lesions produced by
kainic acid injections in the rat]. C.R.Seances Acad.Sci.D. 288 (12):991-994
Epelbaum J., Arancibia L. T., Kordon C., Ottersen O. P., Ben Ari Y. (1979) Regional distribution of
somatostatin within the amygdaloid complex of the rat brain. Brain Res. 174 (1):172-174
Ottersen O. P., Ben Ari Y. (1979) Afferent connections to the amygdaloid complex of the rat and cat. I.
Projections from the thalamus. J.Comp Neurol. 187 (2):401-424
Storm-Mathisen J., Iversen L. L. (1979) Uptake of [3H]Glutamic acid in excitatory nerve endings: light
and electronmicroscopic observations in the hippocampal formation of the rat. Neuroscience 4 (9):12371253
Taxt T., Storm-Mathisen J. (1979) Tentative localization of glutamergic and aspartergic nerve endings in
brain. J.Physiol (Paris) 75 (6):677-684
Ben Ari Y., Lagowska Y., Le Gal La Salle, Tremblay E., Ottersen O. P., Naquet R. (1978) Diazepam
pretreatment reduces distant hippocampal damage induced by intra-amygdaloid injections of kainic acid.
Eur.J.Pharmacol. 52 (3-4):419-420
Grofova I., Ottersen O. P., Rinvik E. (1978) Mesencephalic and diencephalic afferents to the superior
colliculus and periaqueductal gray substance demonstrated by retrograde axonal transport of horseradish
peroxidase in the cat. Brain Res. 146 (2):205-220
Bjorklid E., Storm-Mathisen J., Storm E., Prydz H. (1977) Localization of tissue thromboplastin in the
human brain. Thromb.Haemost. 37 (1):91-97
Divac I., Fonnum F., Storm-Mathisen J. (1977) High affinity uptake of glutamate in terminals of
corticostriatal axons. Nature 266 (5600):377-378
Ottersen O. P., Vegge T. (1977) Ultrastructure and distribution of intercellular junctions in corneal
endothelium. Acta Ophthalmol.(Copenh) 55 (1):69-78
31
Storm-Mathisen J. (1977) Glutamic acid and excitatory nerve endings: reduction of glutamic acid uptake
after axotomy. Brain Res. 120 (2):379-386
Storm-Mathisen J. (1977) Localization of transmitter candidates in the brain: the hippocampal formation
as a model. Prog.Neurobiol. 8 (2):119-181
Storm-Mathisen J. (1977) Localization of putative transmitters in the hippocampal formation: with a note
on the connections to septum and hypothalamus. Ciba Found.Symp. (58):49-86
Rinvik E., Grofova I., Ottersen O. P. (1976) Demonstration of nigrotectal and nigroreticular projections in
the cat by axonal transport of proteins. Brain Res. 112 (2):388-394
Storm-Mathisen J. (1975) High affinity uptake of GABA in presumed GABA-ERGIC nerve endings in rat
brain. Brain Res. 84 (3):409-427
Storm-Mathisen J. (1975) Accumulation of glutamic acid decarboxylase in the proximal parts of
presumed GABA-ergic neurones after axotomy. Brain Res. 87 (1):107-109
Fonnum F., Grofova I., Rinvik E., Storm-Mathisen J., Walberg F. (1974) Origin and distribution of
glutamate decarboxylase in substantia nigra of the cat. Brain Res. 71 (1):77-92
Karlsson A., Fonnum F., Malthe-Sorenssen D., Storm-Mathisen J. (1974) Effect of the convulsive agent
3-mercaptopropionic acid on the levels of GABA, other amino acids and glutamate decarboxylase in
different regions of the rat brain. Biochem.Pharmacol. 23 (21):3053-3061
Storm-Mathisen J. (1974) Proceedings: GABA as a transmitter in the central nervous system of
vertebrates. J.Neural Transm. Suppl 11 (0):227-253
Storm-Mathisen J. (1974) GABA as a transmitter in the central nervous system of vertebrates. J.Neural
Transm. Suppl 11 (0):227-253
Storm-Mathisen J., Guldberg H. C. (1974) 5-Hydroxytryptamine and noradrenaline in the hippocampal
region: effect of transection of afferent pathways on endogenous levels, high affinity uptake and some
transmitter-related enzymes. J.Neurochem. 22 (5):793-803
Storm-Mathisen J. (1974) Choline acetyltransferase and acetylcholinesterase in fascia dentata following
lesion of the entorhinal afferents. Brain Res. 80 (2):181-197
Storm-Mathisen J., Fonnum F. (1972) Localization of transmitter candidates in the hippocampal region.
Prog.Brain Res. 36:41-58
Storm-Mathisen J. (1972) Glutamate decarboxylase in the rat hippocampal region after lesions of the
afferent fibre systems. Evidence that the enzyme is localized in intrinsic neurones. Brain Res. 40 (2):215235
Barstad J. A., Fonnum F., Lilleheil G., Storm-Mathisen J. (1971) [Cholinergic transmission]. Tidsskr.Nor
Laegeforen. 91 (8):574-579
Storm-Mathisen J., Fonnum F. (1971) Quantitative histochemistry of glutamate decarboxylase in the rat
hippocampal region. J.Neurochem. 18 (6):1105-1111
Flood P. R., Fonnum F., Storm-Mathisen J. (1970) Choline acetyltransferase and acetylcholinesterase in
myo-tendinous and neuro-muscular junctions of mouse skeletal muscle. Experientia 26 (9):964-965
32
Fonnum F., Storm-Mathisen J., Walberg F. (1970) Glutamate decarboxylase in inhibitory neurons. A
study of the enzyme in Purkinje cell axons and boutons in the cat. Brain Res. 20 (2):259-275
Fugelli K., Storm-Mathisen J., Fonnum F. (1970) Synthesis of gamma-aminobutyric acid in fish
erythrocytes. Nature 228 (275):1001
Storm-Mathisen J. (1970) Quantitative histochemistry of acetylcholinesterase in rat hippocampal region
correlated to histochemical staining. J.Neurochem. 17 (6):739-750
Fonnum F., Storm-Mathisen J. (1969) GABA synthesis in rat hippocampus correlated to the distribution
of inhibitory neurons. Acta Physiol.Scand. 76 (1):35A-36A
Mellgren S. I., Storm-Mathisen J. (1966) Oxidative enzymes, glycogen and lipid in striated muscle. A
histochemical study in the atlantic Hagfish (Myxine glutinosa (L.)). Z.Zellforsch. 71:169-188
Storm-Mathisen J., Mellgren S. I. (1965) Some observations concerning the role of phenazine
methosulfate in histochemical dehydrogenase methods. J.Histochem.Cytochem. 13:408-409
Storm-Mathisen J., Blackstad T. W. (1964) Cholinesterase in the hippocampal region. Distribution and
relation to architectonics and afferent systems. Acta Anat. 56:216-253
Flood P. R., Storm-Mathisen J. (1962) A third type of muscle fibre in the parietal muscle of the atlantic
Hagfish Myxine glutinosa (L)? Z.Zellforsch. 58:638-640
33