Download KEY

To ensure that the aerosol product is delivered in the proper and desired form, a
suitable ……. Should used :
a) Propellant.
b) Valve.
c) Product concentrates.
d) Actuator
e) Mounting cup
. ………….. is the aerosol device assigned to deliver a given dose of medication
a) Propellant.
b) Container.
c) Valve.
d) Product concentrates
e) Gasket
When the active ingredients are dispersed in the propellant to form foam
aerosols, The type of the Aerosol system is :
a) Solution System
b) Emulsion Based System
c) Suspension or Dispersion Systems
d) Stable foam Systems
e) Quick-Breaking Foams
Which of the followings could be used as propellant in aerosols formulation?
a) Fluorinated hydrocarbons
b) Propane
c) butane
d) Nitrogen
e) All of the above
For acidic drugs formulated as Topical Eye drops , The most used salt
derivatives is :
a) Sulfate salt
b) Sosium salt
c) Phosphate salt
d) Nitrate salt
e) acetate salt
Irrigating eye preprations are :
a) Parenteral dosage forms for ophthalmology use
b) A balanced salt solution was developed for hydration and clarity of the cornea
during surgery.
c) Sterile ophthalmic implants
d) Ophthalmic products introduced into the interior structures of the eye during
ocular surgery
e) None
Sterilizations validation for ophthalmic preparations should prove absence of
Pseudomonas aeruginosa .
a. True
b. False
Boric acid in a concentration of 0.9% produces the same osmotic pressure as
does 1.9% sodium chloride.
a. True
b. False
A topical dermatological product is designed to deliver drug:
a. Through percutaneous absorption.
b. Through the skin to the general circulation.
c. Into the skin in treating dermal disorders, with the skin as the target
organ.
d. a&b.
e. All of the above.
When powdered substances are to be incorporated into hydrocarbon bases,
the following agent may be used as the levigating agent:
a. Vasline.
b. Mineral oil.
c. Water.
d. Alcohol.
e. Any of the above.
The highest degree of occlusion is provided by:
a. Yellow Ointment USP and White Ointment USP have the same
occlusivity but different water washability.
b. Hydrophilic Petrolatum USP has high water washability and
occlusivity.
c. Modified Lanolin USP is lanolin processed to reduce the contents of
free lanolin alcohols thus it has better water washability than Lanolin
USP.
d. Hydrophilic Ointment USP has better water washability compared to
Polyethylene Glycol Ointment, NF.
e. None of the above.
Identify the following ointment base:
Cholesterol
30 g
Stearyl alcohol
30 g
White wax
80 g
White petrolatum
80g
a. Lanolin.
b. Hydrophilic Petrolatum.
c. Hydrophilic Ointment.
d. White Ointment.
e. None of the above.
Concerning extemporaneous compounding of ointments, choose the incorrect
statement(s):
a. The pharmacist may mix the components using a glass mortar and
pestle, or a spatula on an ointment slab.
b. If a levigating agent is needed, it is better to choose a volatile one
about equal in volume to the solid material.
c. Geometric dilution is used to incorporate powdered components
within the base.
d. a&b.
e. All of the above.
The following type of ointment base does not contain oleaginous components:
a. Oleaginous bases,
b. Absorption bases,
c. Water-removable bases,
d. Water-soluble bases.
e. c&d.
Concerning ophthalmic ointments and gels, the major route by which drugs
enter the eye is simple diffusion via:
a. The cornea for lipophilic drugs.
b. The cornea for hydrophilic drugs.
c. The conjunctiva and sclera of lipophilic drugs.
d. All of the above.
Compared with ophthalmic solutions, ophthalmic ointments and gels will:
a. Provide extended residence time on the surface of the eye.
b. Decrease the duration of their surface effects.
c. Increase bioavailability for absorption into the ocular tissues.
d. a&c.
e. All of the above.
Transdermal drug delivery system is usually only suitable for drugs of low level
of potency?
a. True
b. False
Which is an example of chemical permeation enhancer surfactant?
a. Methanol
b. pyrolidiones,
c. propylene glycol
d. Cellulose derivatives
e. Pluronic F127
Define the type of TDDS
a. Polymer Membrane Permeation Controlled System
b. Polymer Matrix Diffusion Controlled TDDS System
c. Gradient Controlled TDDS
d. Adhesive Dispersion-Type system
The followings are examples of synthetic polymers EXCEPT?
a. Polysiloxane
b. Cellulose derivatives
c. Silicon rubber
d. Acrylonitryle
Good candidates for diffusion through the intercellular rout of dermal diffusion
are:
a. Substances with high aqueous solubility characteristics
b. Substances with high lipid solubility characteristics
c. None of the above
Hygroscopic nature :
a. Cocoa butter–based suppositories
b. Polyethylene glycol suppositories that do not contain at least 50% water
c. Glycerinated gelatin–based suppositories
d. All of the above
which of the following factors slow down the rectal absorption :
a. Irritated mucosa
b. Mucosa dehydration
c. Cancer of colon
d. All of the above
Polyethylene glycol suppositories do not melt at body temperature but rather
dissolve slowly in the body’s fluids.
a. True
b. False
Oleaginous suppository bases include:
a.
b.
c.
d.
Glyceryl monopalmitate
Glycerinated gelatin
Polyethylene glycol
Bothe a and b