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Monday, April 29 2002 Morning Session Session Chair: Philip Howe, CCF 10:00a-10:15a Sandra Lemmon, CWRU Role of phosphorylation in regulation of endocytosis and actin organization10:15a10:30a Alan Wolfman, CCF Ras isoform function: Location, location, location 10:30a-10:45a Usha Narayanan (Matera lab) Snurportin1 forms a pre-import snRNP complex with SMN and Importin beta 10:45a-11:00a Donald Jacobsen, CCF Homocysteine and Vascular Disease 11:00a-11:15a Neena Singh, CWRU Molecular basis of prion transmission, replication, and pathogenesis. Mid morning session Session Chair: Sandra Lemmon, CWRU 11:45a-12:00a Stanley Hazen, CCF Peroxidases and Inflammatory Disease 12:00p-12:15p Sanjay Pimplikar, CWRU Alzheimer's Disease: Think Inside 12:15p-12:30p Paul DiCorleto, CCF Endothelial Cell Activation 12:30p-12:45p Susann Brady-Kalnay, CWRU PTP regulates adhesion and signaling 12:45p-1:00p Donna Driscoll, CCF Novel posttranscriptional mechanisms that increase protein diversity Afternoon Session Session Chair: Paul DiCorleto, CCF 3:45p-4:00p RichardGibson (Wilson-Delfosse lab), CWRU A RhoGDI-binding defective Mutant of Cdc42Hs Targets to Membranes and Activates Filopodia Formation but Does Not Cycle with the Cytosol of Mammalian Cells 4:00p-4:15p Martha Cathcart, CCF Critical Pathways in Monocyte Inflammatory Responses 4:15p-4:30p Cathy Carlin, CWRU Regulating EGF receptor signaling by membrane trafficking 4:30p-4:45p Hung-Ying Kao, CWRU Mechanism of nucleocytoplasmic shuttling of class II histone deacetylase 4:45p-5:00p Maribel Rico (Egelhoff lab), CWRU Regulation of Myosin Filament Assembly in Dictyostelium discoideumDinner 6:00p-7:00p Keynote Speaker 7:00p-8:00p Hidde Ploegh, Department of Pathology, Harvard Medical School Antigen Presentation in Real TimePoster Sessions 8:00p-11:00p Tuesday, April 30, 2002 Morning Session Session Chair: Virgil Muresan, CWRU 9:00a-9:15a Guy Chisolm, CCF Influence of Specific Lipoprotein Oxidation Products on Select Vascular Cell Functions 9:15a-9:30a Ed Greenfield, CWRU Cell-cell interactions that regulate bone turnover 9:30a-9:45a Paul Fox, CCF Translational Control of Ceruloplasmin Expression 9:45a-10:00a Alan Levine, CWRU How the T lymphocyte may use lipid raft heterogeneity to regulate an immune response 10:00a-10:15a Philip Howe, CCF TGF SignallingMidmorning session Session Chair: Josephine Adams, CCF 10:45a-11:00a Bing-Cheng Wang, CWRU EphA2 Kinase Activation Antagonizes HGF-Induced Renal Epithelial Cell Chemotaxis and Branching Morphogenesis 11:00a-11:15a Richard Morton, CCF Mechanisms of Cholesterol Homeostasis 11:15a-11:30a Virgil Muresan, CWRU APP, Microtubule Motors, and Signaling to the Nucleus 11:30a-11:45a Thomas Weimbs, CCF Trafficking in Polarized Epithelial Cells 11:45a-12:00p Andrei Gudkov, CCF Poliovirus protein 3A regulation of membrane traffic Afternoon Session Session Chair: Ed Greenfield, CWRU 1:00p-1:15p Michael Kinter, CCF Proteomics of oxidative stress-resistant cells 1:15p-1:30p Jack Hensold, CWRU Mechanisms of post-transcriptional regulation of gene expression during differentiation 1:30p-1:45p Josephine Adams, CCF Thrombospondin-Cytoskeletal Connections 1:45p-2:00p Alan Tartakoff , CWRU Concluding Comments Prize ceremony 2:30p-3:00p Departure 3:00 p