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Unit VII: Patterns of Inheritance
AP Biology / Zeiher
Genetic Problem Set VI
1. Individuals showing Down syndrome usually have an extra chromosome 21, so that
their body cells contain 47 chromosomes.
a. At what stages of meiosis I and II could a mistake occur that could result
in the altered chromosome number?
b. In a few cases, 46 chromosomes are present, including two normal
appearing chromosomes 21 and longer than normal chromosome 14.
Explain how this situation could arise.
2. Sketch a cell with three pairs of chromosomes undergoing meiosis, and show
how nondisjunction can result in the production of gametes with entire or missing
chromosomes.
3. How is chromosome gene linkage an exception to the law of independent
assortment?
4. Draw an example of the following chromosomal breakages:
a.
b.
c.
d.
Deletion
Duplication
Translocation
Inversion
Put a caption with each illustration explaining the different forms of chromosomal
breakage.
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