Download SUPPORTING TABLE S1 ATOM CARBON TRANSITIONS PPP

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SUPPORTING TABLE S1
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ATOM CARBON TRANSITIONS PPP/Glycolysis flux determination.
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rxnEq
GLC_EX + ATP = G6P
G6P = F6P
F6P + ATP = F16BP
F16BP = DHAP + GAP
DHAP = GAP
GAP = PGA + NADH + ATP
PGA = PEP
PEP = PYR + ATP
G6P = 6PG + NADPH
6PG = R5P + CO2 + NADPH
R5P + R5P = E4P + F6P
E4P + R5P = F6P + GAP
PYR = AcCOA + CO2 + NADH
AcCOA + OAA = CIT
CIT = ISOCIT
ISOCIT =  KG + CO2 + NADPH
 KG = 0.5 SUCC + 0.5 SUCC + CO2 + ATP + NADH
SUCC = MAL + FADH
MAL = OAA + NADH
PEP + CO2 = OAA + ATP
G6P = G6P_B
F6P = F6P_B
GAP = GAP_B
PGA = PGA_B
PEP = PEP_B
PYR = PYR_B
R5P = R5P_B
E4P = E4P_B
AcCOA = AcCOA_B
 KG =  KG_B
OAA = OAA_B
CO2 = CO2_EX
 KG = GLU
 KG = PRO
OAA = THR
OAA = ASP
PYR = ALA
PYR + PYR = VAL + CO2
PGA = SER
SER = GLY + MeTHF
PYR + PYR = ISV + CO2
ISV + AcCOA = LEU + CO2
PYR + OAA = ILE + CO2
E4P + PEP = SHKM
SHKM + PEP = CHRM
CHRM = PHE + CO2
rxnCTrans
abcdef + X = abcdef
abcdef = abcdef
abcdef + X = abcdef
abcdef = abc + def
abc = cba
abc = abc + X + X
abc = abc
abc = abc + X
abcdef = abcdef + X
abcdef = bcdef + a + X
abcde + fghij = bcde + fgahij
abcd + efghi = efabcd + ghi
abc = bc + a + X
ab + cdef = fedbac
abcdef = abcdef
abcdef = abcde + f + X
abcde = 0.5 bcde + 0.5 edcb + a + X + X
abcd = abcd + X
abcd = abcd + X
abc + d = abcd + X
a=a
abcde = abcde
abcde = abcde
abcd = abcd
abcd = abcd
abc = abc
abc + def = abefc + d
abc = abc
abc = ab + c
abc + def = abefc + d
abcde + fg = fgbcde + a
abc + defg = debfgc + a
abcd + efg = efgabcd
abcdefg + hij = abcdefghij
abcdefghij = hijbcdefg + a
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Carbon atom transitions are represented using letter code (rxnCTrans). For each metabolite,
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carbon atoms are identified using lower case letter to represent successive carbons atoms.
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RxnID is an ID for each reaction and rxnEq is the reaction. “_B” means drain to biomass and
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“_EX” means extracellular. More details about nomenclature are avalaible in the OpenFlux
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Manual.
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Non-conventional abbreviations:
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6PG : 6-Phosphogluconate ; AcCoA : AcetylCoA ;  KG: -Ketoglutarate ; CHRM :
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Chorismic acid ; CIT : Citric acid ; DHAP : Dihydroxyacetone phosphate ; E4P : Erythrose-
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4-Phosphate ; F16BP : Fructose-1,6-bisphosphate ; F6P : Fructose-6-Phosphate ; G6P :
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Glucose-6-Phosphate ; GAP : Glyceraldehyde-3-Phosphate ; GLC: Glucose ; ISOCIT :
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Isocitric acid ; ISV : Isovaline ; MAL : Malic acid ; MeTHF : 5 ;10-
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methylenetetrahydrofolate or formylTHF ; OAA : Oxaloacetic acid ; PEP :
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Phosphoenolpyruvate ; PGA : 3-Phosphoglycerate ; PYR : Pyruvate ; R5P : Ribose-5-
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Phosphate ; SHKM : Shikimic acid ; SUCC : Succinic acid.
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