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PLACE LABEL HERE ACETAMINOPHEN OVERDOSE ORDERS The following orders will be implemented. Orders with a “” are choices and are NOT implemented unless checked. Initial all handwritten order modifications and the bottom of each page when indicated (multipage). 1. Diagnosis Admit as Inpatient __________________________________________________(reason for admission) 2. 3. 4. 5. 6. 7. 8. 9. 10. 11. 12. 13. & Status: Place in Observation _______________________________________________(reason for observation) Unit: ICU IMCU/PCU Medical Floor (with Telemetry) Medical Floor (No Telemetry) Consults: Mental Health consult Other: ______________________________________________________ Suicide Precautions Diagnostics, if not done in ED: STAT acetaminophen level , STAT PT/INR and daily x 3 days STAT liver function tests and daily x 3 days Vitals q ________ hrs Intake and Output q _______ hrs Urinary Retention Orders (form # 31620), initiate if patient has urinary retention or difficulty voiding DVT Mechanical Prophylaxis Sequential compression device (SCD) TED hose Foot pumps Actual weight of patient: ______ kg (Required) Diet: _________________________________________________________________________________________ Nutrition Supplement Orders (form # 31417), initiate if patient meets criteria Activity: _______________________________________________________________________________________ SCHEDULED MEDICATIONS 14. IVF: ______________________________ at ____________ ml/hr 15. Acetylcysteine Therapy: Oral: Mucomyst (acetylcysteine) 140 mg/kg po or NG tube, then 4 hrs after loading dose, give 70 mg/kg po q 4 hrs x 17 doses (18 total doses). May dilute in soft drinks. IV: IV formulation reserved for patients unable to tolerate oral acetylcysteine Acetadote (acetylcysteine) infusion: Total infusion time = 21 hours For patients < 40 kg or those requiring fluid restriction, notify pharmacy to reduce the total volume and recalculate rates to avoid fluid overload 16. Weight (kg) round up to next 5 kg weight Acetadote Loading Dose 150 mg/kg in D5W 250 ml over 60 minutes Acetadote SECOND Dose 50 mg/kg in D5W 500 ml over 4 hours Acetadote THIRD Dose 100 mg/kg in D5W 1,000 ml over 16 hours 40 kg 45 kg 50 kg 55 kg 60 kg 65 kg 70 kg 75 kg 80 kg 85 kg 90 kg 95 kg 100 kg 105 kg > 110 kg MAX 6,000 mg 6,750 mg 7,500 mg 8,250 mg 9,000 mg 9,750 mg 10,500 mg 11,250 mg 12,000 mg 12,750 mg 13,500 mg 14,250 mg 15,000 mg 15,750 mg 16,500 mg 2,000 mg 2,250 mg 2,500 mg 2,750 mg 3,000 mg 3,250 mg 3,500 mg 3,750 mg 4,000 mg 4,250 mg 4,500 mg 4,750 mg 5,000 mg 5,250 mg 5,500 mg 4,000 mg 4,500 mg 5,000 mg 5,500 mg 6,000 mg 6,500 mg 7,000 mg 7,500 mg 8,000 mg 8,500 mg 9,000 mg 9,500 mg 10,000 mg 10,500 mg 11,000 mg Lovenox (enoxaparin) 40 mg SQ q 24 hrs at 1700; if CrCl < 30, give 30 mg SQ q 24 hrs Order writer’s Initials___________ Send copy to pharmacy *3-20583* FORM 3-20583 REV. 07/2012 Page 1 of 2 PLACE LABEL HERE ACETAMINOPHEN OVERDOSE ORDERS The following orders will be implemented. Orders with a “” are choices and are NOT implemented unless checked. Initial all handwritten order modifications and the bottom of each page when indicated (multipage). PRN MEDICATIONS (If > one drug is ordered for the same indication, clinical assessment will be used per policy 520-06) 17. Itching during infusion: Benadryl (diphenhydramine) 25 mg IV q 4 hrs prn 18. Severe pain: Morphine 1-4 mg IV q 3 hrs prn Dilaudid (hydromorPHONE) 0.5-1 mg IV q 3 hrs prn 19. Moderate pain: Toradol (ketorolac) 30 mg IV (or IM if no IV access) q 6 hrs prn (15 mg if > 65 y/o old or < 50 kg) or 10 mg po q 6 hrs prn (maximum combined duration of IV and po Toradol {ketorolac} is 5 days) Other: _____________________________________________________________ 20. Mild pain/temp >100.5F/HA: Ibuprofen 200-400 mg po q 4 hrs prn, may use elixir 21. Nausea/Vomiting: 22. Indigestion: Maalox XS (aluminum/magnesium/simethicone) 30 ml po four times daily prn 23. Stool Softener: Colace (docusate) 100 mg po bid prn; if patient has not had a bowel movement 24. Constipation: Milk of Magnesia (MOM) 30 ml po daily prn 25. Anxiety: Zofran (ondansetron) 4 mg IV q 6 hrs prn Reglan (metoclopramide) 10 mg po or IV q 6 hrs prn (5 mg if > 65 y/o) Phenergan (promethazine) 12.5-25 mg po or per rectum q 4 hrs prn Ativan (lorazepam) 0.5 - 1 mg po q 8 hrs prn Xanax (alprazolam) 0.25 - 0.5 mg po q 6 hrs prn ADDITIONAL ORDERS: ______________________________________________________________________________________ ______________________________________________________________________________________ ______________________________________________________________________________________ ______________________________________________________________________________________ ______________________________________________________________________________________ ______________________________________________________________________________________ ______________________________________________________________________________________ ______________ Date ___________________ Time _________________________________ Physician Signature ___________ PID Number Send copy to pharmacy FORM 3-20583 REV. 07/2012 Page 2 of 2