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MHCP Enrolled Providers – Pharmacies Fee-for-Service PA Criteria Sheet – IBRANCE™ (May 2016) Drug Therapeutic Area Ibrance™ (palbociclib capsules) [Pfizer] Oncology Approval criteria Patient has a diagnosis of estrogen receptor (ER)-positive, human epidermal growth factor receptor 2 (HER2)-negative advanced breast cancer AND Ibrance treatment will be in combination with letrozole as initial endocrine based therapy in postmenopausal women OR In combination with fulvestrant in women with disease progression following endocrine therapy <br> Quantity limit 21 capsules every 28 days <br> Background information IBRANCE is a kinase inhibitor indicated in combination with letrozole for the treatment of postmenopausal women with estrogen receptor (ER)-positive, human epidermal growth factor receptor 2 (HER2)-negative advanced breast cancer as initial endocrinebased therapy for their metastatic disease MHCP Provider Call Center 651-431-2700 or 800-366-5411