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Menstrual disorders Definition A menstrual disorder is a physical or emotional problem that interferes with the normal menstrual cycle, causing pain, unusually heavy or light bleeding, delayed menarche, or missed periods. Description Typically, a woman of childbearing age should menstruate every 28 days or so unless she is pregnant or moving into menopause. But numerous things can go wrong with the normal menstrual cycle, some the result of physical causes, others emotional. These include amenorrhea, or the cessation of menstruation, menorrhagia, or heavy bleeding, and dysmenorrhea, or severe menstrual cramps. Nearly every woman will experience one or more of these menstrual irregularities at some time in her life. Dysmenorrhea Characterized by menstrual cramps or painful periods, dysmenorrhea, which comes from the Greek words for "painful flow," affects nearly every woman at some point in her life. It is the most common reproductive problem in women, resulting in numerous days absent from school, work, and other activities. There are two types: primary and secondary. Primary, or normal cramps, affects up to 90% of all women, usually occurring in women about three years after they start menstruating and continuing through their mid-twenties or until they have a child. About 10% of women who have this type of dysmenorrhea cannot work, attend school, or participate in their normal activities. It may be accompanied by backache, dizziness, headache, nausea, vomiting, diarrhea and tenseness. The symptoms typically start a day or two before menstruation, usually ending when menstruation actually begins. Primary dysmenorrhea is related to the production of prostaglandins, natural chemicals the body makes that cause an inflammatory reaction. They also cause the muscles of the uterus to contract, thus helping the uterus shed the lining built up during the first part of a woman's cycle. Women with severe menstrual pain have higher levels of prostaglandin in their menstrual blood than women who do not have such pain. In some women, prostaglandins can cause some of the smooth muscles in the gastrointestinal tract to contract, resulting in the nausea, vomiting and diarrhea some women experience. Prostaglandins also cause the arteries and veins to expand, so that blood collects in them rather than flowing freely through them, causing pain and heaviness. Yet another reason for severe cramps, particularly in women who have not yet had a baby, is that the flow of the blood and clots through the tiny cervical opening is painful. After a woman has a baby, however, the cervix opening is larger. Secondary dysmenorrhea has an underlying physical cause and primarily affects older women, although it may also occur immediately after a woman begins menstruation. Secondary dysmenorrhea is more serious and is related to some underlying cause. The pain may feel like regular menstrual cramps, but may last longer than normal and occur throughout the month. It may be stronger on one side of the body than the other. Possible causes include: A tipped uterus Endometriosis, a condition in which the same type of tissue found in the lining of the uterus occurs outside the uterus, usually elsewhere in the pelvic cavity Adenomyosis, a condition in which the endometrial lining grows into the muscle of the uterus Fibroids Pelvic inflammatory disease (PID) An IUD A uterine, ovarian, bowel or bladder tumor Uterine polyps Inflammatory bowel disease Scarring or adhesions from earlier surgery Primary dysmenorrhea is typically treated with nonsteroidal anti-inflammatory medications like ibuprofen and naproxen, which studies show help 64 to 100% of women. Birth control pills relieve pain and symptoms in about 90% of women by suppressing ovulation and reducing the amount of menstrual blood. It may take up to three cycles before a woman feels relief. Heat from a heating pad or hot bath, can also help relieve pain.Treatment for secondary dysmenorrhea depends on the underlying cause of the condition. Menstrual cramps Most women have experienced menstrual cramps before or during their period at some point in their lives. For some, it's part of the regular monthly routine. But if your cramps are especially painful and persistent, you should consult your health care professional. Pain from menstrual cramps is caused by uterine contractions, triggered by prostaglandins, hormone-like substances that circulate in your bloodstream. If you having severe menstrual pain, you might also find you have some diarrhea or an occasional feeling of faint where you suddenly become pale and sweaty. That's because prostaglandins speed up contractions in your intestines, resulting in diarrhea, and lower your blood pressure by relaxing blood vessels, leading to lightheadedness. Premenstrual syndrome (PMS) PMS is a term commonly used to describe a wide variety of severe physical and psychological symptoms associated with the menstrual cycle. About 30 to 40 percent of women experience symptoms severe enough to disrupt their lifestyles. PMS symptoms are more severe and disruptive than the typical premenstrual symptoms that as many as 75 percent of all women experience. There are more than 150 documented symptoms of PMS, the most common of which is depression. Symptoms develop about seven to 10 days before your period and disappear once your period begins or soon after. Physical symptoms associated with PMS include: Bloating Swollen, painful breasts Fatigue Constipation Headaches Clumsiness Emotional symptoms associated with PMS include: Anger Anxiety or confusion Mood swings and tension Crying and depression An inability to concentrate No one knows what causes PMS. However, researchers now know that it is not a simple result of an imbalance of estrogen and progesterone—commonly referred to as "female hormones," or any other single hormonal factor. A complex interaction of brain chemicals (such as dopamine, norepinephrine and serotonin) are now suspected of having a more direct relationship in triggering PMS. Exactly how these brain chemicals change with or affect the menstrual cycle remains unclear. Estrogen excesses, progesterone deficiencies, vitamin B6 deficiencies, low levels of serotonin (a brain chemical that affects mood), an excess of prolactin (a protein hormone that induces lactation) and altered glucose metabolism are among the many different theories that attempt to explain PMS, but none has been proven. PMS differs from other menstrual cycle symptoms because symptoms: tend to increase in severity as the cycle progresses. are relieved when menstrual flow begins or shortly after. are present for at least three consecutive menstrual cycles. Symptoms of PMS may worsen with age and increase in severity following each pregnancy. If you experience PMS, you may have an increased sensitivity to alcohol at specific times during your cycle. Women with this condition often have a sister or mother who also suffers from PMS, suggesting a genetic component exists for the disorder. Premenstrual dysphoric disorder (PMDD) Premenstrual dysphoric disorder is far more severe than the typical PMS. Women who experience PMDD (about 3 to 8 percent of all women) say it significantly interferes with their lives. Experts equate the difference between PMS and PMDD to the difference between a mild tension headache and a migraine. The most common symptoms of PMDD are heightened irritability, anxiety and mood swings. Women who have a history of major depression, postpartum depression or mood disorders are at higher risk for PMDD than other women. Although some symptoms of PMDD and major depression overlap, they are different: PMDD-related symptoms (both emotional and physical) are cyclical. When a woman starts her period, the symptoms subside within a few days. Depression-related symptoms, however, are not associated with the menstrual cycle. Without treatment, depressive mood disorders can persist for weeks, months or years. Amenorrhea There are two types of amenorrhea: primary and secondary. Overall, they affect 2-5% of childbearing women, a number that is considerably higher among female athletes (possibly as high as 66%). Primary amenorrhea occurs when a girl at least 16 years old is not menstruating. Young girls may not have regular periods for their first year or two, or their periods may be very light, a condition known as oligomenorrhea. A light flow is nothing to worry about. But if the period has not begun at all by age 16, there may be something wrong. Amenorrhea is most common in girls who are severely underweight and/or exercise intensely, both of which affect the amount of body fat necessary to trigger the release of hormones that, in turn, begins puberty. Secondary amenorrhea occurs in women of childbearing age after a period of normal menstruation and is diagnosed when menstruation has stopped for three months. It can occur in women of any age. Causes and symptoms The only symptom of primary amenorrhea is delayed menstruation. In addition to low body weight or excessive exercise, other causes of primary amenorrhea include Turner's syndrome, a birth defect related to the reproductive system, or ovarian problems. In 2003, a group of researchers reported on a new genetic mutation associated with primary amenorrhea. In secondary amenorrhea, the primary symptom is the ceasing of menstruation for at least three months. Causes include pregnancy or breastfeeding, sudden weight loss or gain, intense exercise, stress, endocrine disorders affecting the thyroid, pituitary or adrenal glands, including Cushing's Syndrome and hyperthyroidism, problems with or surgery on the ovaries, including removal of the ovaries, cysts or ovarian tumors. Amenorrhea in athletes or dancers is frequently associated with two other disordersosteopenia, or reduced bone mass, and eating disorders. This combination is sometimes called the female athlete triad. Osteopenia is of concern because it can lead to premature osteoporosis. Treatment For primary amenorrhea with no underlying problem, no treatment is necessary, and a wait-and-see approach is often adopted. If women have genetic or hormonal abnormalities, amenorrhea is often treated with oral contraceptives that contain combinations of estrogen and progestin. Side effects include bloating, weight gain and acne, although some birth control pills actually improve acne. Progestins, or synthetic progesterone, are also used alone to "jump start" a woman's period. They include medroxyprogesterone (Provera, Amen, Depo-Provera), norethindrone acetate (Aygestin, Norlutate), and norgestrel (Ovrel). If the amenorrhia is due to a physical problem, such as a closed vagina, surgery may be required. With secondary amenorrhia, treatment depends on the cause. Hormonal imbalances are treated with supplemental hormones. Tumors or cysts may require surgery. Obesity may require a diet and exercise regimen, while amenorrhia resulting from too much dieting or exercise necessitates lifestyle changes. Alternative treatment There are several herbal remedies that can bring on menstruation, including: black cohosh, cramp bark, chasteberry, celery, turmeric, and marsh mallow. Numerous relaxation techniques, such as meditation, deep breathing, and yoga can help reduce stress and its affects on menstruation. Prevention Simply following a healthy exercise and nutritional program can help prevent amenorrhea, as can reducing stress and learning relaxation techniques. Also, avoiding excessive alcohol intake and quitting smoking may prevent missed periods.