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Locally Advanced (Unresectable) or Metastatic Gallbladder Cancer/Cholangiocarcinoma Chemotherapy Algorithm Locally Advanced (Unresectable) or Metastatic Gallbladder Cancer/Cholangiocarcinoma Fit for chemotherapy? No Clinical Trials or Supportive Care Yes Gemcitabine +/Cisplatin Progression Clinical Trials or Supportive Care Funded via NHS England Regimen Details May be applied for via Cancer Drugs Fund Wherever possible, eligible patients should be offered access to treatment as part of clinical trials