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King Saud University Diploma Course In Basic Biochemistry Final Exam , First Semester 2008-2009 Student's Name: ------------------------------------ Student's No. ------------------------- Q1. Put (√ ) or (X) , correct the (X) one: 10 marks. 1. Atoms of different elements have same masses and properties. ( ) 2. Glucogenic a.a´ produces glycogen as an end product ex. Trp. ( ) 3. Increase in the PH , causes first α-smino gp.will donate a proton , then α-carboxyl gp. will donate a proton. ( ) 4. Pepsin has it's maximum activity at acidic PH. ( ) 5. Sucrose is a reducing sugar, since it can reduce Cu++ to Cu +. ( ) 6. The simplest and most abundant lipids is cholesterol. ( ) 7.The Pyrimidine Adenine always pair with Purine Thymine by 3 hydrogen bonds.( ) 8. UMP is Uridine-5'- mono- phosphate may present in DNA. ( ) 9. Hormones are always proteins. ( ) 10. One of the factors that regulate Hormones action is Temperature. ( ) Q2. Fill in the Blanks: 10 marks. 1. The no. of electrons lost or gained to form stable system is called………………….. 2. Peptide ……………… contain a peptide bond formed between two a.a´ by a …… ……………………… bond. 3. In chromatography : molecules are separated on the bases of …………………… Between two phases: ……………………. and ……………………………………… 4. At V.max the enzyme is ………………. with it's ………………. and can function no further. 5. Competitive inhibition can be reversed by ………………………………………….. 6. If the CHO contain 2 or more different types of sugar we called it ………………… ………….. ex. ………………………….. contains repeating units of ……………….. …………. and ……………………………….. 7. Fatty acid general formula is …………………………. 8. glycerol + 3 F.A → …………………………………. 9. The difference between Nucleoside and Nucleotide is ……………………………... ………………………………………………………………………………………….. 10. Enzyme ……………………… catalysis the replication of DNA. 5 marks. Q3. Give an example of: 1. Interactions stabilizing the 3˚ structure of protein. 2. Protein denaturation . 3. Sphingolipids. 4. Defense protein. 5. Irreversible inhibitor. Q4. Draw the chemical structure of: 1. Pyrimidine. 4. ATP 2. Tyrosine 5 marks. 3. D-Fructose 5. Deoxyribonucleotide. 5 marks. Q5. Match: 1. Replication of DNA. 2. Sulfhydryl gp. 3. Chromatography 4. Iodine no. 5. Steroid Hormone RS Fats Cholesterol Cysteine Cell Division Q6. Answer one of the following: 1. Write short note about : _____ _____ _____ _____ _____ 5 marks. A. Replication of DNA. B. The difference between DNA and RNA. 2. Enzyme Inhibition. Good Luck..