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Pelvic Floor Dysfunction Chen Xiaojun Ob&Gyn Hospital Fudan Uniiversity Obstetrics & Gynecology Hospital Fudan University What you need to know • Anatomy of pelvic floor and etiology of pelvic floor dysfunction • Definition and major types of pelvic organ prolapse • Principle of treatment • Types of urinary incontinence Obstetrics & Gynecology Hospital Fudan University • Pelvic Organ Prolapse • Lower Urinary Tract disorder • Anorectal Disorder Obstetrics & Gynecology Hospital Fudan University Pelvic floor dysfunction • Not life threatening • But life quality worsening Obstetrics & Gynecology Hospital Fudan University Pelvic Floor Obstetrics & Gynecology Hospital Fudan University Pelvic floor Pelvic outlet Anterior pubic symphysis Posterior apex of coccys Bilateral descending ramus of pubis ascending ramus of ischium ischial tuberosity ischial spine Obstetrics & Gynecology Hospital Fudan University Pelvic floor Pelvic Supports Muscle Fasciae and ligament • 神经支配; Obstetrics & Gynecology Hospital Fudan University Pelvic Floor Pelvic diaphragm • • • Funnel-shaped fibromuscular partition Forms the primary supporting structure for the pelvic contents Composition – Levator ani – Coccygeus muscles – their superior and inferior fasciae • Forms the ceiling of the ischiorectal fossa Obstetrics & Gynecology Hospital Fudan University 女性会阴.浅表分割 阴蒂clitoris------------------------------尿道外口--------------------------External urethral orific 阴道口--------------------------Vaginal orific 外层 ---------------------坐骨海绵体肌 ischocavernosus --------------------球海绵体肌bulbocavernosus ---------------会阴浅横肌 superficial transverse perineal muscle -----------------------肛门外括约肌 External anal sphincter 由会阴浅筋膜与肌肉组成, 包括会阴浅横肌、球海绵体肌、坐骨海绵体肌和肛门外括约肌。 女性会阴和尿生殖膈 ---------------------尿道括约肌 urethral sphincter 尿生殖膈下筋膜---------------Inferior fascia of urogenital diaphragm ----------------尿生殖膈上筋膜 Superior fascia of urogenital diaphragm 会阴深横肌 Deep transverse perineal muscle 中层 为尿生殖膈,由上、下两层坚韧筋膜及一层薄肌肉组成。 覆盖在耻骨弓及两坐骨结节间所形成的骨盆出口前部的三角平面上。 包括会阴深横肌及尿道括约肌。 Levator ani Strongest support of pelvic floor 女性骨盆横膈:俯视图 ----------------------耻骨阴道肌 Pubovaginal muscle Tendinous fascia pelvis “the white line” ---------------------耻骨直肠肌 Puborectal muscle -----------------------耻骨尾骨肌 Pubococcygeal muscle 髂骨尾骨肌 Iliaccoccygeal muscle 坐骨尾骨肌 ischiococcygeus 内层 称为盆膈,为盆底最里层,最坚韧的组织。 由肛提肌、盆筋膜组成,有尿道、阴道、直肠贯穿其中。 Levator ani • Support pelvic organs • Inforce sphincters Obstetrics & Gynecology Hospital Fudan University The hammock hypothesis Obstetrics & Gynecology Hospital Fudan University 3 levels of support • Level 1 - Apical Support Superior suspension of the vagina to the cardinaluterosacral complex • Level 2—Lateral Support Lateral attachment of the upper 2/3 of the vagina • Level 3 – distal support Fusion of the vagina into the urogenital diaphragm and perineal body Obstetrics & Gynecology Hospital Fudan University Obstetrics & Gynecology Hospital Fudan University Pelvic floor 3 compartments • Anterior compartment (bladder and urethra) • Middle compartment (vagina and uterus) • Posterior compartment (anorectus) Obstetrics & Gynecology Hospital Fudan University Integral theory Prolapse and most pelvic floor symptoms such as urinary stress, urge, abnormal bowel and bladder emptying, and some forms of pelvic pain, mainly arise, for different reasons, from laxity in the vagina or its supporting ligaments, a result of altered connective tissue. Obstetrics & Gynecology Hospital Fudan University Pelvic floor dysfunction • • Level 1 – prolapse of the uterus or anterior vaginal vault Level2/3 – prolapse of anterior or posterior vaginal wall • Anterior compartment – lower urethral tract dysfunction Middle compartment – Enterocele Cystocele Uterine prolapse Posterior compartment Rectocele Anorectal dysfunction • • Obstetrics & Gynecology Hospital Fudan University PELVIC ORGAN PROLAPSE Obstetrics & Gynecology Hospital Fudan University Pelvic Organ Prolapse (POP) • Bulge or protrusion of pelvic organs and their associated vaginal segments into or through the vagina • Incidence increases with aging – anterior pelvic organ prolapse 34.3% – posterior wall prolapse 18.6% – uterine prolapse in 14.3% Obstetrics & Gynecology Hospital Fudan University Pelvic Organ Prolapse (POP) • Vaginal delivery as a significant risk factor • History of hysterectomy; obesity ; history of previous prolapse operations; race • Optional surgical treatment remains elusive Obstetrics & Gynecology Hospital Fudan University Pathophysiology • • Attenuation of the supportive structures – endopelvic connective tissue – levator ani muscular support by actual tears or “breaks” by neuromuscular dysfunction Continuous abdominal pressure Obstetrics & Gynecology Hospital Fudan University Definitions • • • • Rectocele Enterocele Cystocele Uterine prolapse – Procidentia Obstetrics & Gynecology Hospital Fudan University Definitions Obstetrics & Gynecology Hospital Fudan University Symptoms • • • • • • • Pelvic organ prolapse Symptoms of voiding dysfunction – Urinary incontinence – Urinary urgency and frequency – Obstructive voiding symptoms – Urinary retention and upper renal compromise Defecatory problems (e.g., constipation, diarrhea, tenesmus, fecal incontinence) Pelvic pain Back and flank pain Overall pelvic discomfort Dyspareunia Obstetrics & Gynecology Hospital Fudan University Symptoms Obstetrics & Gynecology Hospital Fudan University Physical examination • • • • • • • Divide the pelvis into compartments Apical compartment ---- Graves speculum or Baden retractor The anterior and posterior compartments ---- univalve or Sims' spe Rectovaginal examination ---- distinguish a posterior vaginal wall d a dissecting apical enterocele Anterior lateral detachment defect----Baden retractor Valsalva is encouraged Standing straining examination Obstetrics & Gynecology Hospital Fudan University Pelvic Organ Prolapse Quantitation System Obstetrics & Gynecology Hospital Fudan University Pelvic Organ Prolapse Quantitation System Obstetrics & Gynecology Hospital Fudan University Pelvic Organ Prolapse Quantitation System >1 Obstetrics & Gynecology Hospital Fudan University • Pelvic Muscle Function Assessment • Bladder Evaluation Obstetrics & Gynecology Hospital Fudan University Treatment • Nonsurgical Therapy – Mild to moderate prolapse – Desire future childbearing – Not suitable or desiring surgery Always conservative therapy first!!! Obstetrics & Gynecology Hospital Fudan University Conservative Management • • • Pelvic floor muscle training (PFMT) Lifestyle intervention – weight loss – reduction of activities that increase intra–abdominal pressure Mechanical Devices − Pessary Obstetrics & Gynecology Hospital Fudan University Surgical Management • • • • • OPTIONAL!!! Relieve symptoms Restore vaginal anatomy Vaginal, abdominal, and laparoscopic routes Involve a combination of repairs directed to the anterior vagina, vaginal apex, posterior vagina, and perineum • NONE IS PERFECT! Obstetrics & Gynecology Hospital Fudan University Surgical Management Procedures • Restorative: use the patient's endogenous support structures • Compensatory: replace deficient support with permanent graft material • Obliterative: close or partially close the vagina. Obstetrics & Gynecology Hospital Fudan University Obstetrics & Gynecology Hospital Fudan University Key points • With the aging of the population, pelvic organ prolapse is an increasingly common condition seen in women. • Causes of pelvic organ prolapse are multifactorial and result in weakening of the pelvic support connective tissue and muscles as well as nerve damage. • Patients may be asymptomatic or have significant symptoms such as those relating to the lower urinary tract, pelvic pain, defecatory problems, fecal incontinence, back pain, and dyspareunia. • Physical examination includes thoughtful attention to all parts of the vagina, including the anterior, apical, and posterior compartments, levator muscle, and anal sphincter complex. Obstetrics & Gynecology Hospital Fudan University Key points • Nonsurgical treatment options include pelvic floor muscle training and the use of intravaginal devices. • Surgical treatment involves an individualized, multicompartmental approach consistent with the patient‘s previous treatment attempts, activity level, and health status. Obstetrics & Gynecology Hospital Fudan University LOWER URINARY TRACT DISORDERS Obstetrics & Gynecology Hospital Fudan University Normal Urethral Closure Obstetrics & Gynecology Hospital Fudan University Urinary incontinence • • Stress Urinary Incontinence • Most common type of urinary continence in women • Leaking when sneezing, coughing, or exercise • Urethral sphincter defect and/or urethral hypermobility Urge Urinary Incontinence and Overactive Bladder • Most common form of incontinence in older women • Involuntary leakage of urine accompanied by or immediately preceded by urgency • May or may not be caused by detrusor overactivity Obstetrics & Gynecology Hospital Fudan University Urinary incontinence • Mixed Incontinence • Have symptoms of both stress and urge urinary incontinence • In older women mixed and urge incontinence is predominate Obstetrics & Gynecology Hospital Fudan University Stress urinary incontinence • Incidence US 15-35 % Korea 50% China 18.9 % • Age Postmenopausal women 17%. Affects 50 million people in the world. Obstetrics & Gynecology Hospital Fudan University Pathophysiology • Stress urinary incontinence Incontinence caused by anatomic hypermobility of the urethra Incontinence caused by intrinsic sphincteric weakness or deficiency • Urgent urinary incontinence Bladder Innervation Obstetrics & Gynecology Hospital Fudan University Risk factors • • • • • Age Obesity Functional impairment Cognitive impairment Pregnancy and delivery Obstetrics & Gynecology Hospital Fudan University Evaluation • • • • Hisotory (medications, operations...) Quality of life measures Physical examination (Q–tip test) Primary care level tests Voiding Diary Urinalysis Postvoid Residual Volume Cough Stress Test Pad Tests Obstetrics & Gynecology Hospital Fudan University Evaluation • Advanced testing Urodynamics Uroflowmetry Filling cystometry Voiding cystometrography Imaging tests Neurophysiological tests ……. Obstetrics & Gynecology Hospital Fudan University Nonsurgical treatment • Lifestyle Changes Weight loss Postural change Decrease caffeine intake • Physical Therapy -- SUI Pelvic floor muscle training • Behavioral Therapy and Bladder Training – UI & OAB • Vaginal and urethral devices --SUI Obstetrics & Gynecology Hospital Fudan University Vaginal and Urethral Devices Obstetrics & Gynecology Hospital Fudan University Medications • Stress incontinence – α– adrenergic activity • Urge Incontinence and Overactive Bladder – anticholinergic agents Obstetrics & Gynecology Hospital Fudan University Surgical Treatment for Stress incontinence Obstetrics & Gynecology Hospital TVT/SPARC Fudan University Key Points Obstetrics & Gynecology Hospital Fudan University Anorectal Dysfunction Obstetrics & Gynecology Hospital Fudan University Clasification • Defecatory dysfunction --- constipation Infrequent stools, typically fewer than three bowel movements per week. • Fecal Incontinence Obstetrics & Gynecology Hospital Fudan University Key points • Defecatory dysfunction and fecal incontinence are common conditions that have tremendous psychosocial and economic implications. • The differential diagnosis for anorectal dysfunction is broad and can be classified into systemic factors, anatomic and structural abnormalities, and functional disorders. • A thorough history and physical examination is critical for the evaluation of fecal incontinence and defecatory dysfunction, as well as appropriate ancillary testing. Obstetrics & Gynecology Hospital Fudan University Key points • Treatment of anorectal dysfunction should focus on treatment of the underlying condition with nonsurgical management attempted before surgery. • Overlapping sphincteroplasty is the procedure of choice for fecal incontinence caused by a disrupted anal sphincter. Obstetrics & Gynecology Hospital Fudan University Questions • • • • Which structure is the strongest support of the pelvic floor? The types of pelvic organ prolapse and their definition. The principle of treatment of pelvic organ prolapse. Types of urinary incontinence and their definition. Obstetrics & Gynecology Hospital Fudan University Thank you ! Obstetrics & Gynecology Hospital Fudan University