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The Islamic University of Gaza Faculty of Sceince Department Biology Histology 2nd mid term 3/ 5 /2011 60 minutes St. Name:…………………………………………………St. No…………………... Answer all the following questions Q. I- Choose the correct statement (20 points) 1.Which of the following is NOT primarily composed of connective tissue? a. Blood b. Bone c. Tendon d. Intervertebral disc 2. Which of the following is not associated with connective tissue? a. Tightly packed cells b. Extracellular fibers c. Tissue fluid d. Ground substance e. None of the above; all of the above are seen with connective tissue " 3. Which of the following can be classified as "embryonic connective tissue"? a. Cartilage b. Mucous connective tissue c. Adipose tissue d. Bone e. Blood 4. What type of adipose tissue tends to increase as humans age? a. Brown adipose tissue b. White adipose tissue c. Unilocular adipose tissue d. Multilocular adipose tissue e. Both b and c 5- Which of the following is NOT primarily composed of connective tissue? a. Bone marrow b. Articular cartilage c. Heart d. Mesenchyme e. Fat 1 6.Which one of these cells is not a cell type routinely found in loose connective tissue? a. Fibroblast b. Microglia c. Histiocyte d. Plasma cell e. Mast cell 7.What does connective tissue develop from? a. Mesothelium b. Mesenchyme c. Mesangial cells d. Mesentery e. Wharton's jelly 8. Which of the following is NOT a glycosaminoglycan in cartilage? a. Chondroitin sulfate b. Proteoglycans c. Keratan sulfate d. Hyaluronic acid e. All of the above are glycosaminoglycans in cartilage 11. Which type of cartilage is characterized by the presence of chondrocytes sitting in lacunae? a. Hyaline cartilage b. Elastic cartilage c. Fibrocartilage d. All of the above e. None of the above 12.Which type of cartilage is highly vascular? a. Hyaline cartilage b. Elastic cartilage c. Fibrocartilage d. All of the above e. None of the above 13.Which type of cartilage is found in the larynx? a. Hyaline cartilage b. Elastic cartilage c. Fibrocartilage d. Both a and b e. All of the above 14. Which is incorrect about compact bone? a. is also called dense bone. b. has the Haversian system. c. Found in long bone d. its matrix is mineralized and lacks collagen fibers. e. lined with endostium 2 15.What are Sharpey's fibers? a. Elastic fibers b. Collagen fibers c. Reticular fibers d. Trabeculae e. Dense regular connective tissue 16. What is bone formation called when the bone is formed from a cartilage template? a. Intraosseous b. Diaphyses c. Intramembranous d. Endochondral e. Endosteum 17. What type of muscle contains actin and myosin? a. Skeletal muscle b. Cardiac muscle c. Smooth muscle d. Both "a" and "b" e. "a" "b" and "c 18.What is actin? a. Myofilament b. Myosin c. Muscle fibe d. Myofibril e. Myocardium 19. Red fibers differ from the white fibers in all the following except a. make up slow-twitch muscle b. are more resistant to fatigue? c. have more mitochondria and use aerobic metabolism d. are skeletal muscle fibers e. less glycogen and myoglobin. 20. Which is incorrect about the development of a long bone in the adult a. Develops from a small hyaline cartilage. b. Cartilaginous model grows in length and width c. Cartilaginous model ossifies by endochondral and perichondral ossification. d. A membrane of mesenchymal connective tissue converts into bone. 3 Matching a- Match each cell with its characteristic (A) 1-Osteoclast 2-Chondrocyte (B) ) derived from B lymphocytes ( ( )contains metachromatically stained granules 3-Histocyte 4-Plasma cell ( ( ) produce collagen and ground substance in c.t. ) mature bone cell 5-Osteoblast ( ) produces the cartilaginous matrix? 6-Osteocyte ( ) connective tissue macrophage 7-Fibroblast ( ) involved in laying down new bone? 8-Mast cell ( ) a multinucleated cell with acidophilic foamy cytoplasm. b- Match each of the following connective tissue with its appropriate organ (A) 1-Perimysium 2-Perineurium 3-Perichondrium 4-Periosteum 5-Endosteum ( ( ( ( ) ) ) ) (B) Bone Cartilage. Nerve fascicles. Muscle fascicles What type of connective tissue makes up each of the following? Dermis of the skin Tendon Stroma of the organs Which type of cartilage forms Intervertebral disc? Incomplete rings of trachea? Ear pinna? Which type of bone forms Flat bone of the skull? Sternum? Scapula? 3.Which type of muscle fibers found in each of the following? a. Tongue? 4 b. Blood vessel? c. Walls of the viscera? d. Heart? Give reason(s) 1- Hyaline cartilage is characterized by a glassy matrix 2- Smooth muscle has unstriated appearance 3- Blood can be classified as "specialized connective tissue"? 4- True or false? Correct the false ones 1-( )Mesenchyme is a differentiated tissue found in the embryo 2-( )Hyaline cartilage at the articular site of bone lacks perichondrium. 3-( )The muscle fibers of esophagus are of the skeletal type. 4-( )Haversian system is the cylindrical structure with bone, also called Osteon. 5-( )Hyaline cartilage is the most abundant type of cartilage. 6-( )Spongy bone is also referred to as cancellous bone 7-( )Howship's lacuna is a space seen underneath an osteoclast. 8-( )Intercalated discs are specialized junctions between cardiac cells. 9-( )Pericytes are rare in the adult c.t. but they are persist along capillaries as UMCs 10-( ) Volkmann's canals connect the Haversian canals together and with the enosteal blood vessels. 11-( ) The matrix of cartilage is basophilic due to the presence of sulphated glycosaminoglycans. 22. Which is incorrectly defined? Myofilaments are actin and myosin. 5 The muscle fiber is a muscle cell. A myofibril is a longitudinal bundle of myofilaments within a muscle cell. Myocardium is the muscular layer of the heart. 23.What is myosin? a. Muscle fibers b. Myofibrils c. Myocardium d. Myofilament e. Muscle cell 24.Which fiber type is make up fast-twitch muscle? a. Red fibers b. White fibers c. Intermediate fibers d. All of the above e. None of the above 2.Which of the following is NOT a fiber found in connective tissue? a. Collagen fiber b. Elastic fiber c. Reticular fiber d. Purkinje fiber 3.Which of the following can be classified as "specialized connective tissue"? a. Mesenchyme b. Mucous connective tissue c. Blood d. Loose connective tissue 10.Which of the following is NOT primarily composed of connective tissue? a. Spinal cord b. Pubic symphysis c. Ligament d. Areolar tissue e. Organ capsule 6