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SUPPLEMENTARY TABLE II
Genes changed in kidney of Gcdh -/- mice
classification
gene description
fold
change
accession #
signal
transduction
frizzled-related protein
ral guanine nucleotide dissociation stimulator,-like 1
rhotekin
2.1
2.0
2.0
NM_011356
NM_016846
BC013820
solute carrier
mitochondrial carrier family, member 25 (Slc25a25)
organic anion transporter family, member 1a1 (Slc21a1)
solute carrier family 41, member 2 (Slc41a2)
cationic amino acid transporter, y+ system, member 11 (Slc7a11)
organic anion transporter, member 7 (Slc22a7)
monocarboxylic acid transporter, member 4 (Slc16a4)
organic anion transporter family, member 1a6 (Slc21a13)
sodium-dependent dicarboxylate transporter, member 3 (Slc13a3)
solute carrier family 12, member 6 (Slc12a6)
cationic amino acid transporter, y+ system, member 13 (Slc7a13)
sodium-dependent dicarboxylate transporter, member 2 (Slc13a2)
solute carrier family 39 (zinc transporter), member 14 (Slc39a14)
organic anion transporter, member 19 (Slc22a19)
solute carrier family 5 (iodide transporter), member 8 (Slc5a8)
organic cation transporter, member 2 (Slc22a2)
solute carrier family 17 (sodium phosphate), member 3 (Slc17a3)
solute carrier family 4 (anion exchanger), member 2 (Slc4a2)
sodium/glucose cotransporter, member 2 (Slc5a2)
solute carrier family 1, member 1 (Slc1a1)
solute carrier family 26, member 4 (Slc26a4)
solute carrier family 4 (anion exchanger), member 1 (Slc4a1)
monocarboxylic acid transporter, member 7 (Slc16a7)
nucleoside transporter, member 3 (Slc29a3)
monocarboxylic acid transporter, member 1 (Slc16a1)
cationic amino acid transporter, y+ system, member 8 (Slc7a8)
facilitated glucose transporter, member 1 (Slc2a1)
urea transporter, member 2 (Slc14a2)
4.0
4.0
2.6
2.6
1.7
1.7
1.7
1.7
1.6
1.6
1.6
1.5
1.5
1.4
1.4
1.4
0.7
0.7
0.7
0.6
0.6
0.6
0.6
0.6
0.5
0.5
0.4
BC019978
NM_013797
BC026874
NM_011990
BC026598
BC025441
NM_023718
BB497312
NM_133648
NM_028746
BC013493
BB399837
BC021384
BC017691
NM_013667
NM_134069
NM_009207
BC022226
U75214
NM_011867
NM_011403
NM_011391
BI158381
NM_009196
NM_016972
BM209618
AF366052
3.3
2.8
2.8
2.3
2.1
2.0
1.9
0.7
0.5
0.5
0.5
0.4
0.4
0.4
0.4
BC024605
AU019171
AK004192
NM_008596
NM_010864
BC014701
NM_053097
NM_019404
BC019966
AK019319
BC015076
BC024320
NM_021359
U03434
NM_021272
transport, other camello-like 5
/ cytoskeleton tocopherol (alpha) transfer protein
CD36 antigen
mitsugumin 29
myosin Va
potassium voltage-gated channel, shaker-related subfamily, beta member 1
camello-like 3
arginine vasopressin receptor 2
aquaporin 2
apolipoprotein E
epithelial V-like antigen 1
CEA-related cell adhesion molecule 2
integrin beta 6
ATPase, Cu++ transporting, alpha polypeptide
fatty acid binding protein 7, brain
transcription/
cell cycle
energy/
metabolism
ceruloplasmin
aquaporin 4
chloride intracellular channel 3
calcium/calmodulin-dependent protein kinase II, delta
laminin, beta 2
major urinary protein 1 / major urinary protein 2
spondin 1, (f-spondin) extracellular matrix protein
ATP-binding cassette, sub-family B (MDR/TAP), member 1B
0.2
0.2
0.2
0.2
0.2
0.1
0.1
0.1
NM_021272
U48399
AK009020
BM239047
BC026051
NM_031188
BC020531
NM_011075
ankyrin repeat domain 6
cell death-inducing DNA fragmentation factor, alpha subunit-like effector A
suppressor of cytokine signaling 2
delta sleep inducing peptide, immunoreactor
polymerase (DNA directed), kappa
inhibitor of DNA binding 1
histone deacetylase 11
anaphase promoting complex subunit 4
midkine
cyclin-dependent kinase inhibitor 1C (P57)
8.6
3.3
2.3
2.3
2.3
1.9
0.4
0.4
0.3
0.1
BM199504
NM_007702
NM_007706
NM_010286
AB027563
U43884
BC016208
BC024870
M34328
NM_009876
cytochrome P450, family 24, subfamily a, polypeptide 1
glypican 1
ornithine decarboxylase, structural 1
monoacylglycerol O-acyltransferase 2
dehydrogenase/reductase (SDR family) member 8
phospholipase A2, group IID
acetoacetyl-CoA synthetase
phosphoenolpyruvate carboxykinase 1, cytosolic
uridine phosphorylase 2
UDP-glucuronosyltransferase 2 family, member 5
carbonic anhydrase 4
SA rat hypertension-associated homolog
trimethyllysine hydroxylase, epsilon
angiotensin converting enzyme
aminolevulinic acid synthase 1
ATPase, class VI, type 11A
renin 1 structural
heme binding protein 1
arginase type II
acetyl-Coenzyme A acyltransferase 2
angiotensinogen
microsomal glutathione S-transferase 1
cytosolic acyl-CoA thioesterase 1
stearoyl-Coenzyme A desaturase 2
sterol-C4-methyl oxidase-like
folate hydrolase
phosphoserine aminotransferase 1
retinol dehydrogenase 11
3-phosphoglycerate dehydrogenase
steroidogenic acute regulatory protein
7-dehydrocholesterol reductase
P lysozyme structural
7.0
4.0
2.8
2.6
2.6
2.5
2.5
2.5
2.3
2.3
2.1
2.1
2.1
2.1
1.9
1.9
1.9
0.5
0.5
0.5
0.5
0.4
0.4
0.4
0.4
0.4
0.4
0.3
0.3
0.3
0.2
0.1
D89669
NM_016696
S64539
BB414982
NM_053262
AK004232
BC026817
AW106963
BC027189
NM_009467
NM_007607
AB022340
NM_138758
M55333
BC022110
NM_015804
NM_031192
AF117613
AV002218
BB718075
AK018763
BC009155
NM_134188
BB459479
AK005441
NM_016770
BC004827
AK012056
AA561726
BG067261
NM_007856
AV066625
molecular
chaperons
expressed
sequence tags
hydroxysteroid dehydrogenase-1, delta<5>-3-beta
3-hydroxy-3-methylglutaryl-Coenzyme A synthase 2
glutaryl-Coenzyme A dehydrogenase
0.1
0.0
0.0
NM_008293
AK004902
NM_008097
DnaJ (Hsp40) homolog, subfamily A, member 4
DnaJ (Hsp40) homolog, subfamily B, member 1
heat shock protein 1B
heat shock protein 1B / heat shock protein 1A
heat shock protein 1A
DnaJ (Hsp40) homolog, subfamily A, member 1
DnaJ (Hsp40) homolog, subfamily B, member 4
heat shock protein 105
3.5
2.9
2.5
2.3
2.1
1.9
1.9
1.9
BC022948
NM_018808
M12573
M12573
M12573
NM_008298
BC017161
BI499717
RIKEN cDNA C730048C13 gene
rearranged L-myc fusion sequence
RIKEN cDNA 130002F13 gene
DNA segment, Chr 6, ERATO Doi 253, expressed
hypothetical protein BC006605, expressed sequence
--dedicator of cytokinesis 9
expressed sequence AI114950
expressed sequence AI788959
2.0
2.0
2.0
1.9
0.5
0.4
0.4
0.3
0.1
BB667865
BF020283
AI788755
BQ174328
BC006605
AU046270
BB795072
BB224153
BC028826