Download Dr Nizar Mhaidat - Jordan University of Science and Technology

Curriculum Vitae
Dr. Nizar M. Mhaidat
Assistant Professor
PhD, Clinical Oncology & Immunology
January 2010
Dr. Nizar Mhaidat:
Jordan University of Science and Technology
Faculty of Pharmacy
Department of Clinical Pharmacy
PO. Box 3030, Irbid 22110, Jordan
Phone:
Work: 0096227201000-23542 or -26774
Home: 0096227300039
Mobile: 00962785338533
Email: [email protected]
[email protected]
Education:
PhD Clinical Oncology & Immunology, 2006, Cancer Research Unit,
Faculty of Medicine, The University of Newcastle, NSW, Australia.
MS.c Clinical Pharmacy, 2001, Faculty of Pharmacy, Jordan University
of Science & Technology, Jordan.
BS.c Pharmacy, 1998, Faculty of Pharmacy, Jordan University of
Science & Technology, Jordan.
High school, 1994, Green Hill International High School, Athens, Greek.
Position Held and Experience:
1.
Chairman of the Clinical Pharmacy Department at Jordan University
of Science & Technology, JUST, 2007.
2.
Assistant Professor, Clinical Oncology and Immunology; JUST, 2006.
3.
Active member of Jordanian Food & Drug Administration (JFDA) of
drug re-registration, 2008.
4.
Head of Clinical Pharmacy Department in King Abdullah University
Hospital (KAUH), 2008.
5.
Active member of the Jordanian Pharmaceutical Continuous Health
Education, 2007.
6.
Active reviewer of Journal of cellular and molecular medicine, 2008.
7.
Active member of the American Association of Cancer Research
(AACR), 2007.
8.
Head of the internal pharmacy (KAUH), 2001-2003.
9.
Clinical Pharmacist at the KAUH, 1999-2001.
10.
General Manager of the local market; Al-Noor drug store, 1998-1999.
Publications and International Congresses Presentations:
1. Nizar M. Mhaidat, Yufang Wang, Kelly A. Kiejda, Xu Dong
Zhang, and Peter Hersey: Docetaxel-Induced Apoptosis in
Melanoma Cells is Dependent on Activation of Caspase-2;
Molecular Cancer Therapeutics, 2007.
2. Nizar M. Mhaidat, Xu Dong Zhang, Chen Chen Jiang, and Peter
Hersey: Docetaxel-induced apoptosis of human melanoma is
mediated by activation of JNK and inhibited by the map kinase
ERK1/2 pathway; Clinical Cancer Research, 2007.
3. Chen Chen Jiang, Li Hua Chen, Susan Gillespie, Kelly A. Kiejda,
Nizar Mhaidat, Yu Fang Wang, Rick Thorne, Xu Dong Zhang,
and Peter Hersey: Tunicamycin sensitize human melanoma cells to
tumor necrosis factor-related apoptosis-inducing ligand-induced
apoptosis by up-regulation of TRAIL-R2 via the unfolded protein
response; Cancer Research, 2007.
4. Rick F. Thorne, Nizar Mhaidat, Kylie Ralston, and Gordon F.
Burns; Shed gangliosides provide detergent-independent evidence
for type-3 glycosynapses, BBRC, 2007.
5. Rick F. Thorne, Nizar Mhaidat, Kylie Ralston, and Gordon F.
Burns; CD36 is a receptor for oxidized high-density lipoprotein:
Implications for the development of atherosclerosis, FEBS Letters,
2007.
6. Nizar M. Mhaidat, XD Zhang, John Allen, Kelly Kiejda, Rodney
Scoot, and Peter Hersey: Temozolomide Induces Senescence but
not Apoptosis in Human Melanoma Cells; British Journal of
Cancer, 2007.
7. Nizar M. Mhaidat, Rick Thorne, XD Zhang, and Peter Hersey:
Regulation of docetaxel-induced apoptosis of human melanoma
cells by different isoforms of protein kinase c; Molecular Cancer
Research, 2007.
8. Nizar M. Mhaidat, Rick Thorne, XD Zhang, and Peter Hersey:
Docetaxel-induced apoptosis of human melanoma is determined by
the level of beta tubulin III. FEBS Letters, 2008.
9. Nizar Mhaidat, Xu Dong Zhang, Ping Wang, Susan Gillespie, and
Peter Hersey. Antimicrotubule agent-induced activation of
ERK1/2 protects human melanoma cells from apoptosis mediated
by c-Jun N-terminal kinase. American Association for Cancer
Research (AACR) Annual Meeting, USA, 2005.
10. Nizar Mhaidat, Xu Dong Zhang, Chen Chen Jiang, and Peter
Hersey. Overcoming resistance of human melanoma to
chemotherapy-induced apoptosis, AACR Annual Meeting, USA,
2006.
11. Nizar Mhaidat, Jing Jing Wu, Xu Dong Zhang, and Peter Hersey.
Human Melanoma Cells Selected for Resistance to Apoptosis by
Prolonged Exposure to Cisplatin, HMRI annual meeting, Australia,
2005.
12. Nizar M. Mhaidat, Rick Thorne, XD Zhang, and Peter Hersey.
Docetaxel induces JNK-dependent apoptosis of human melanoma
by induction of ER stress, Apoptosis, 2008.
13. Nizar M. Mhaidat, XD Zhang, and Peter Hersey. Overcoming
resistance to apoptosis in cancer therapy. Adv Exp Med Biol. 2008.
14. Nizar M. Mhaidat, Peter Hersey. Endoplasmic reticulum; Foe or
Friend in Cancer Cells. Int Rev Cytol, 2006.
15. Nizar M. Mhaidat, Karem Al-zoubi, Suleiman Al-Sweedan.
Prevalence of depression in cancer patients. Supportive cancer
care, 2009.
16. Karem Al-zoubi, Nizar M. Mhaidat. Bacterial resistance:
awareness among medical teams (physicians, pharmacists and
nurses) in north Jordan. Jordan Pharmaceutical Journal, 2009.
17. Nizar M. Mhaidat. Sensitization of colorectal cancer cells to
paclitaxel-induced apoptosis by inhibition of MEK is caspase-4
dependant (In press), 2009.
18.Ahmad Al-Kofahi, Nizar M. Mhaidat. Screening of Jordanian
medicinal plants for inhibition against clinical isolates of
Helicobacter Pylori (submitted).
19.Nizar M. Mhaidat. Involvement of ER stress in chemotherapyinduced apoptosis of cancer cells. Advances in cancer research;
from Lab. To Clinic. AACR Meeting in Jordan, 2008.
20. Karem Alzoubi, Nizar Mhaidat, Sayer Al azzam. Prevalence of
migraine and tension-type headache among adult in Jordan. J.
Headache Pain, 2009.
21.Nizar M. Mhaidat, Feras Alali, Sina Matalqah, Ismail Matalka,
Saied Jaradat, Noor Al-Sawalha, Rick Thorne. Inhibition of MEK
sensitizes paclitaxel-induced apoptosis of human colorectal cancer
cells by downregulation of GRP78. Anticancer Drugs, 2009.
22.Al-Azzam SI, Al-Ajlony MJ, Al-Khateeb T, Alzoubi KH, Mhaidat
N, Ayoub A. An audit of the precipitating factors for haemolytic
crisis among glucose-6-phosphate dehydrogenase-deficient
paediatric patients. J Med Screen., 2009.
23.Nizar Mhaidat, UPR signalling in colorectal cancer. ACCR
Meeting in Boston, USA, 2009.
Current Research Projects:
1.
Chemotherapy-induced apoptosis of cancer cells.
2.
Death and survival signal transduction pathways in human
cancer cells.
3.
Endoplasmic reticulum (ER) stress and unfolded protein
response (UPR); Implications in cancer management.
4.
Endosomes formation and resistance to Taxanes-induced
apoptosis.
5.
Multidrug resistance protein in clinical response of cancer
patients.
Supervision of MSc thesis:
1.
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4.
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10.
Nour Ahmad Sawalha, Paclitaxel-Induced ER-Stress of Human
colorectal Cancer, 2007.
Aseera Mefleh Quwaimani, Altholactone-induced apoptosis of
human colorectal cancer, 2008.
Sohad Ali Barakat, Involvement of MEK/ERK signaling
pathway in the resistance of human colorectal cancer cells to
doxorubicin-induced apoptosis, 2008.
Reem Mazen Al-Hammori, In vitro toxicity study of
altholactone on human colorectal cancer cells: comparison with
5-Fourouracil, 2009.
Saleh Naser Abu-Shuqair, Annonacin; Evaluation of antitumour
activity and safety index in colorectal cancer and normal cells,
2009.
Haeder Kathem Rabeie, Annonacin; Evaluation of antimicrobial
activity and safety index, 2009.
Maha Burhan Al-Omari, Evaluation of colchicine effect on
Cytokine Production from Peripheral Blood Mononuclear Cells
of Type 1 Diabetic Patients, 2009.
Osama Shoqran, Evaluation of MDR1 polymorphism in
Hodgkin Lymphoma patients, 2009.
Ibrahim Hamdan, Synthesis and biological evaluation of
oxadiazole derivatives, 2010.
Israa Trad, Determination the antibiotic susceptibility of
Pseudomonas aeruginosa and Staphylococcus aureus on
biofilm bacteria: an in vitro study, 2010.