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Table S1 ISWI-enriched sequences. (A) Genomic sequences enriched for ISWI are listed according to their chromosome location. Each ISWI-bound sequence is defined by a start (peakStart) an end (peakEnd), and by a peakScore function that reflects the width and height of each peak (see Materials and Methods for details). In case an ISWI peak falls in the proximity of a gene, the relative annotation for the gene region bound together with the distance from the TSS is reported. (B) List of genes bound by ISWI and whose expression changes at least x1.5 fold or (C) x4 fold in ISWI mutant total larvae (Corona et al., 2007). Positive log2(ISWI/wild type) ratio signal values correspond to genes negatively regulated by ISWI, while negative values correspond to genes positively regulated by ISWI. (A) Chromosome chr2L chr2L chr2L chr2L chr2L chr2L chr2L chr2L chr2L chr2L peakStart 20870 70273 72372 95120 130365 143426 154099 222264 248977 431475 peakEnd 21310 70615 73393 95850 130998 143768 156381 222800 250660 431720 peakScore 12.44 9.78 12.75 13.64 17.01 12.81 13.67 11.24 14.04 9.51 GeneName CG2671-RB CG11372-RA CG11372-RA CG11376-RA CG3164-RA CG11454-RA CG3709-RA CG3696-RB CG3696-RA CG4114-RA Strand + + + + + RelatiiveAnnotation intronexon promoter prom_exon intronexon prom_exon exon prom_exon promoter intron exon Distance TSS 282 -1943 495 734 109 222 81 -586 976 345 chr2L chr2L chr2L chr2L chr2L chr2L chr2L chr2L chr2L chr2L chr2L chr2L chr2L chr2L chr2L chr2L chr2L chr2L chr2L chr2L chr2L chr2L chr2L chr2L chr2L chr2L chr2L chr2L chr2L chr2L chr2L 479745 482719 483980 487203 516723 576128 701358 733330 842187 870461 1005946 1421659 1665853 1667376 1749166 1982314 2038049 2147560 2164159 2174731 2250899 2364699 2433151 2701413 2833159 3079018 3172578 3469130 3579128 3657630 3712988 480572 483158 484322 487836 516968 577246 701837 733575 842529 872743 1006973 1422001 1666098 1667815 1749411 1982656 2038932 2147902 2164598 2174976 2251241 2365488 2433396 2701658 2833501 3079263 3172823 3469375 3579373 3659015 3713718 10.78 13.66 11.29 12.16 10.91 10.42 11.65 9.51 12.81 18.77 16.37 11.29 9.51 12.44 10.91 12.81 18.33 12.81 13.66 9.51 11.29 11.24 9.51 9.51 11.29 9.51 9.51 9.51 9.51 20.21 16.37 CG4427-RA intergenic intergenic intergenic intergenic CG13687-RA CG17941-RA intergenic CG3365-RA CG33526-RA intergenic CG5481-RA CG31666-RA CG31666-RA CG17646-RA CG7289-RA CG4244-RA CG7261-RA CG3166-RB CG3166-RB CG17240-RA CG3664-RF CG9885-RA CG31690-RA intergenic CG9660-RB CG34406-RA CG3238-RA CG3242-RA CG10033-RI CG2818-RA + + + + + + + + + + + + + + + + + promoter OUT OUT OUT OUT prom_exon intron OUT intron intronexon OUT promoter promoter promoter intron intronexon exonintron exon intron intron exon prom_exon intron intron OUT intron prom_exon exon exon promoter prom_exon -476 -4000 -4000 -4000 -4000 -101 13370 -4000 333 507 -4000 -1381 -1870 -250 11820 252 471 213 14370 3895 200 -141 4820 26711 -4000 11770 50 754 1515 -1371 -20 chr2L chr2L chr2L chr2L chr2L chr2L chr2L chr2L chr2L chr2L chr2L chr2L chr2L chr2L chr2L chr2L chr2L chr2L chr2L chr2L chr2L chr2L chr2L chr2L chr2L chr2L chr2L chr2L chr2L chr2L chr2L 3762105 3784916 3793879 3867095 4178983 4186959 4224243 4282306 4290409 4464002 4572331 4882839 4966640 4968095 4972654 4975672 5255948 5269571 5325503 5364855 5436124 6253524 6323650 6338405 6423925 6480570 6558166 6636710 6647957 6648830 6921299 3762350 3786810 3794124 3867437 4180101 4187883 4225555 4282648 4290654 4464344 4572627 4883181 4967467 4969989 4973093 4975917 5256193 5271465 5326145 5365585 5436369 6254351 6324283 6338844 6424364 6481785 6558605 6636955 6648202 6649463 6921932 9.51 19.56 9.51 14.33 13.02 11.55 17.98 9.78 9.51 11.29 12.23 10.3 12.12 18.16 9.78 9.51 9.51 19.28 17.01 12.88 9.51 11.29 12.16 10.01 9.78 18.42 15.23 9.51 9.51 10.23 17.01 CG31772-RA CG31958-RA CG3921-RA CG3980-RB intergenic CG31961-RB CG3702-RA CG15427-RC CG15427-RC CG15436-RA CG33196-RC CG11924-RA CG8882-RA CG3756-RA CG3782-RA CG8890-RA CG14026-RA CG14026-RA CG14023-RB CG11020-RD CG31647-RB CG9486-RA CG9491-RC CG9493-RA CG9523-RA CG9537-RA CG11015-RA CG31635-RB CG31635-RB CG31635-RB CG10377-RB + + + + + + + + + + + + + + + + + exon prom_exon exon promoter OUT prom_exon intronexon promoter intron exon intron prom_exon intronexon intronexon promoter exon intron prom_exon promoter exonintron exon promoter prom_exon prom_exon prom_exon prom_exon exonintron exon exon prom_exon prom_exon 2160 45 3339 -447 -4000 368 2198 -673 7381 532 19484 103 724 39 -1103 1223 15282 835 -888 18984 3030 -1937 200 -131 -191 222 586 12255 1008 -58 -49 chr2L chr2L chr2L chr2L chr2L chr2L chr2L chr2L chr2L chr2L chr2L chr2L chr2L chr2L chr2L chr2L chr2L chr2L chr2L chr2L chr2L chr2L chr2L chr2L chr2L chr2L chr2L chr2L chr2L chr2L chr2L 7186884 7219319 7351019 7388279 7417358 7533272 7994777 8040999 8057912 8083874 8139316 8278028 8306796 8314864 8364055 8424163 9387953 9450497 9704207 9964961 10009810 10095600 10246332 10260215 10265710 10291841 10320458 10412965 10436429 10471580 10506689 7187129 7219711 7351361 7388524 7417603 7533711 7995129 8041729 8058157 8084605 8139561 8278370 8307041 8315109 8365755 8424505 9388392 9450839 9705907 9966273 10010782 10095942 10250657 10260945 10266052 10292086 10320813 10413210 10436674 10471825 10507128 9.51 16.06 11.29 9.51 9.51 13.66 11.29 11.24 9.51 14.37 9.51 12.81 9.51 9.51 14.2 9.78 9.78 9.78 14.99 14.68 10.42 11.29 16.86 12.65 9.78 9.51 11.29 9.51 9.51 9.51 15.23 CG4496-RA CG13784-RC CG4969-RA CG5149-RA CG5229-RA CG34374-RF CG7228-RC CG7429-RA CG14472-RA CG31605-RD CG8552-RA CG8049-RC CG7830-RA CG7806-RA CG13383-RB CG13388-RC CG3752-RA CG3779-RA CG31710-RA CG4651-RA CG4758-RB CG34109-RC CG5686-RA CG5671-RF CG4946-RA CG5604-RA CG5381-RA CG5355-RA CG5198-RA CG31719-RA CG7438-RA + + + + + + + + + + + + + + - exon intron intronexon promoter exonintron intron promoter exonintron exon1 intron exon promoter intronexon exonintron exonintron intron intron intron intronexon promoter intronexon intron prom_exon intronexon intronexon intron intron exon intronexon exon prom_exon 1061 514 10754 -153 5028 10931 -771 250 13556 818 20136 -501 1269 3568 39 4461 784 839 887 -1694 -63 1684 -1430 437 544 314 1164 484 561 2644 -128 chr2L chr2L chr2L chr2L chr2L chr2L chr2L chr2L chr2L chr2L chr2L chr2L chr2L chr2L chr2L chr2L chr2L chr2L chr2L chr2L chr2L chr2L chr2L chr2L chr2L chr2L chr2L chr2L chr2L chr2L chr2L 10964009 10967222 10968845 11051298 11263928 11271203 11274929 11700303 11807294 11808255 12020339 12021697 12024658 12038976 12096803 12341475 12483219 12534017 12974570 12991567 13204263 13348919 13365588 13389540 13550299 13598962 13842360 14233347 14346642 14353045 14541279 10965818 10968120 10969187 11051737 11264270 11271739 11275174 11700548 11807539 11808500 12020972 12022136 12025388 12039512 12098892 12341914 12483464 12534359 12974815 12991812 13204799 13349261 13368022 13389785 13550641 13599207 13843212 14233592 14346887 14354648 14541524 16.48 16.72 9.78 9.78 12.81 14.27 9.51 9.51 10.21 9.51 10.23 15.23 10.42 11.24 18.96 12.44 9.51 12.81 9.51 9.51 12.6 9.78 16.77 9.51 14.26 12.07 10.42 9.51 9.51 11.38 9.51 CG33507-RB CG33129-RB CG33129-RA CG31868-RA CG6392-RA CG33695-RA CG33695-RA intergenic CG14938-RC CG14938-RC CG6734-RA CG6734-RA intergenic CG6756-RA CG5336-RA intergenic CG42281-RH CG42281-RF CG3762-RC intergenic CG5547-RB CG16826-RA CG6523-RA CG7099-RA CG7147-RE CG9254-RA CG33306-RA CG4551-RA CG18125-RA CG7516-RA intergenic + + + + + + + + + + + + + + prom_exon intronexon promoter intron exon exonintron exon OUT intron exon prom_exon promoter OUT promoter intronexon OUT exon intron prom_exon OUT exonintron exonintron exonintron exon intron promoter intronexon intron prom_exon intronexon OUT -785 481 -810 15479 5080 1745 5325 -4000 1555 594 282 -978 -4000 -701 5 -4000 232 6382 71 -4000 764 1300 340 2027 307 -1898 956 638 -110 1233 -4000 chr2L chr2L chr2L chr2L chr2L chr2L chr2L chr2L chr2L chr2L chr2L chr2L chr2L chr2L chr2L chr2L chr2L chr2L chr2L chr2L chr2L chr2L chr2L chr2L chr2L chr2L chr2L chr2L chr2L chr2L chr2L 14705610 15038017 15271313 15273327 15318182 15399260 15501814 15765310 15829577 16251789 16287734 16525614 16680023 16720617 16785055 16815658 16817410 17030348 17258049 17526801 17769970 17784683 18148075 18149653 18152028 18460970 18694860 18839384 19034613 19135593 19146927 14705952 15038456 15271558 15273669 15318427 15399505 15502156 15765555 15829824 16252131 16288176 16525859 16681432 16720959 16785300 16816297 16817655 17030690 17258294 17527143 17770215 17785025 18148710 18150288 18152370 18461215 18695784 18839629 19034858 19136032 19147172 11.29 13.66 9.51 9.78 9.51 9.51 11.29 9.51 9.51 11.29 10.01 9.51 17.29 11.29 9.51 17.01 9.51 9.78 9.51 11.29 9.51 11.29 14.76 20.13 9.78 9.51 13.97 9.51 9.51 9.78 9.51 intergenic CG4180-RA CG11861-RB CG11861-RC CG15259-RB CG18482-RA CG4162-RA CG3793-RA intergenic CG4993-RA CG7664-RA CG5953-RB CG4711-RA CG17903-RA CG17927-RF CG31991-RB CG31991-RD intergenic CG15138-RA CG15144-RA intergenic intergenic CG15154-RA CG15154-RA CG15154-RA intergenic CG10383-RA CG10600-RB CG31800-RA CG10719-RA CG10719-RA + + + + + + + + + + + + + + + OUT intronexon exon promoter exon intron intronexon exon OUT promoter promoter intron intronexon intron exon5 promoter exonintron OUT intron exon OUT OUT intron intron intronexon OUT prom_exon exon promoter intron intron -4000 620 192 -1487 596 6844 2876 1203 -4000 -174 -227 7140 672 915 16599 -686 425 -4000 2560 2023 -4000 -4000 4017 2439 211 -4000 100 160 -279 2007 13244 chr2L chr2L chr2L chr2L chr2L chr2L chr2L chr2L chr2L chr2L chr2L chr2L chr2L chr2L chr2L chr2L chr2L chr2L chr2L chr2L chr2L chr2L chr2L chr2L chr2L chr2L chr2L chr2L chr2R chr2R chr2R 19165696 19190508 19192233 19322586 19342119 19359833 19361813 19489730 19491211 19526272 19586748 19590514 19809216 20094771 20417172 20462767 20680698 20798758 20823246 20921178 21139983 21178619 21753661 22168375 22247368 22427882 22472067 22690518 19014 129373 432441 19166135 19191238 19193010 19322928 19342364 19360175 19362865 19490169 19492135 19526711 19587090 19591341 19809461 20095113 20417514 20463012 20681040 20799100 20823491 20921617 21140325 21178961 21753906 22169008 22248673 22428224 22472497 22690860 19550 129715 432783 15.23 12.88 10.23 11.29 9.51 9.78 15.12 9.78 12.16 9.78 11.29 10.01 9.51 12.81 11.29 9.51 12.81 12.81 9.51 15.23 9.78 12.81 9.51 13.02 14.18 11.29 13.27 9.78 13.26 11.29 13.22 CG10719-RC CG17348-RA CG17348-RA intergenic CG17559-RA CG17559-RA CG17559-RA CG10194-RA CG18094-RA CG10166-RA intergenic intergenic intergenic CG10722-RA CG10954-RA CG2493-RA CG1962-RB CG9328-RB CG9331-RE CG9342-RA CG1099-RA CG9242-RA CG11628-RA CG1832-RB CG12775-RA CG17489-RA CG17494-RB CG40439-RB CG17683-RB CG17665-RA CG40293-RB + + + + + + + + + + + + + + + promoter exonintron intron OUT intron intron intronexon prom_exon exonintron prom_exon OUT OUT OUT exon exon exon exon intron promoter intronexon intronexon intron intron intronexon prom_exon intron prom_exon exonintron intronexon intronexon promoter -1650 528 2276 -4000 20982 3220 885 133 1188 -167 -4000 -4000 -4000 979 283 559 749 1199 -1066 1452 2198 907 3677 450 -187 1297 -199 269 532 900 -1596 chr2R chr2R chr2R chr2R chr2R chr2R chr2R chr2R chr2R chr2R chr2R chr2R chr2R chr2R chr2R chr2R chr2R chr2R chr2R chr2R chr2R chr2R chr2R chr2R chr2R chr2R chr2R chr2R chr2R chr2R chr2R 482376 616098 717111 982699 1304065 1327402 1549280 2018335 2019984 2031125 2434394 2522474 2810781 2900978 2998255 3033350 3036213 3133705 3240019 3294946 3417807 3419157 3477594 3509541 3585603 3586671 3667451 3776871 3804405 3842939 3916511 482912 616731 717453 983041 1304534 1327647 1549622 2018774 2020326 2031952 2434675 2522913 2811317 2901223 2998597 3034856 3036846 3134338 3240749 3295191 3418246 3419596 3477936 3509980 3586043 3587595 3667696 3777310 3804793 3843184 3916950 12.95 11.23 11.29 11.82 11.23 9.51 11.29 10.01 11.29 11.24 13.47 11.23 12.25 9.51 9.78 14.81 18.13 15.02 19.09 9.51 11.23 12.44 12.81 13.66 12.44 12.76 9.51 13.66 12.74 9.51 12.44 CG17484-RA CG17704-RF CG14464-RC intergenic CG42345-RB CG42345-RB CG8426-RA CG1765-RB CG1765-RB CG1765-RE CG9397-RI CG3152-RA CG3358-RA CG10106-RA CG12833-RA CG12172-RA CG12828-RA CG1851-RA CG17800-RE CG11166-RG CG1600-RC CG1600-RA CG2092-RA CG30492-RC CG30493-RB CG30496-RA CG30497-RA intergenic CG1877-RD CG14764-RA intergenic + + + + + + + + + + + + + + + + + prom_exon prom_exon exonintron OUT intron intron exon intronexon promoter intron intron exon prom_exon intron intron promoter intronexon promoter intron exon promoter intron prom_exon promoter promoter prom_exon intron OUT prom_exon exon OUT -153 79 558 -4000 444 23669 1274 869 -731 13095 44771 1073 174 1340 12364 -1099 612 -758 28990 257 -1236 1110 142 -987 -962 125 2545 -4000 -83 315 -4000 chr2R chr2R chr2R chr2R chr2R chr2R chr2R chr2R chr2R chr2R chr2R chr2R chr2R chr2R chr2R chr2R chr2R chr2R chr2R chr2R chr2R chr2R chr2R chr2R chr2R chr2R chr2R chr2R chr2R chr2R chr2R 4019253 4283438 4299854 4553324 4611887 4625651 4685117 4776963 4777836 4779485 4830186 5017264 5030852 5171525 5260722 5435705 5442293 5466171 5481927 5749181 5846690 5856855 5987982 5989819 6132871 6237242 6309404 6317529 6363351 6484454 6963148 4019692 4284440 4300875 4554248 4612617 4626672 4686312 4777208 4778566 4779827 4831013 5017703 5031388 5172158 5260967 5436053 5442635 5466708 5482269 5749717 5847129 5857585 5988938 5991422 6133116 6237584 6309843 6318065 6363790 6484960 6963393 10.01 14.92 12.76 10.23 17.13 12.25 17.09 9.51 13.64 11.29 12.25 12.44 15.59 11.29 9.51 9.78 12.81 13.26 12.81 11.24 12.44 10.61 14.44 11.85 9.51 9.78 10.01 18.45 13.66 14.08 9.51 CG2163-RA CG11641-RB CG2121-RB CG8732-RD CG8411-RA CG8740-RC CG33141-RB CG8272-RA CG8272-RA CG8269-RA intergenic CG18659-RB CG8055-RA CG2049-RB CG13954-RB CG1888-RA intergenic CG34407-RD CG1902-RA CG1516-RI CG12130-RB CG12131-RA CG17870-RD CG17870-RD CG3454-RA CG34363-RD CG33474-RA CG42236-RA CG12891-RB CG2368-RJ CG33473-RB + + + + + + + + + + + + + + + + + + - exonintron exonintron promoter prom_exon exonintron intron prom_exon exon exon intronexon OUT promoter intronexon exonintron exon promoter OUT promoter intron promoter prom_exon intronexon prom_exon intron exon intron prom_exon intronexon promoter intron intron 555 8970 -1136 109 488 2838 -306 1818 703 312 -4000 -1976 295 760 896 -1420 -4000 -454 511 -401 -143 756 -76 2084 4620 45264 -113 581 -585 13509 24237 chr2R chr2R chr2R chr2R chr2R chr2R chr2R chr2R chr2R chr2R chr2R chr2R chr2R chr2R chr2R chr2R chr2R chr2R chr2R chr2R chr2R chr2R chr2R chr2R chr2R chr2R chr2R chr2R chr2R chr2R chr2R 6995018 7036771 7071136 7193937 7195006 7275718 7339378 7429268 7469661 7488865 7528012 7539241 7741719 7855644 7905527 7914393 8148918 8323814 8342849 8500279 8524681 8540703 8631541 8643147 8767402 8803734 9020655 9095210 9317801 9390214 9479855 6995931 7037210 7071478 7194376 7195736 7276060 7339720 7429610 7469906 7489304 7528257 7539777 7742158 7855986 7906160 7914735 8149454 8325805 8343094 8500725 8527642 8541045 8631786 8644556 8767744 8804561 9022452 9095455 9318484 9390556 9481056 12.59 11.55 11.29 10.01 10.23 9.78 12.81 12.81 9.51 12.44 9.51 11.24 9.78 11.29 15.02 11.29 13.26 13.67 9.51 13.66 23.77 11.29 9.51 16.34 11.29 19 13.41 9.51 10.58 12.81 10.87 intergenic CG12391-RA CG7734-RA CG12389-RA CG7745-RA CG30022-RB CG7776-RA intergenic CG10897-RD CG10897-RA intergenic CG34228-RA CG8274-RA CG8979-RB CG8967-RA CG8889-RC CG8472-RA CG8529-RC CG12369-RA CG17759-RG CG8625-RC CG8632-RB intergenic CG12373-RA CG3798-RF CG3845-RC CG34438-RF CG4616-RB CG42321-RN CG6033-RC CG6191-RA + + + + + + + + + + + + + + + + + + + - OUT intronexon intron intronexon intronexon exon promoter OUT intron intron OUT intronexon exon intronexon intron intronexon intron prom_exon intron exonintron intronexon exon OUT prom_exon promoter intron intronexon exon promoter prom_exon prom_exon -4000 570 579 913 -17 393 -172 -4000 356 14251 -4000 128 1815 254 1485 526 2274 -29 2276 257 1936 563 -4000 -51 -245 646 930 1072 -743 -43 385 chr2R chr2R chr2R chr2R chr2R chr2R chr2R chr2R chr2R chr2R chr2R chr2R chr2R chr2R chr2R chr2R chr2R chr2R chr2R chr2R chr2R chr2R chr2R chr2R chr2R chr2R chr2R chr2R chr2R chr2R chr2R 9549295 9763418 9828995 9848230 9870252 10053416 10062185 10240967 10391485 10406585 10509271 10511890 10629726 10641690 10736760 10760200 10893789 10898668 10995369 10997503 11006355 11258438 11417314 11550054 11694905 11787038 11934386 11990754 12038224 12059775 12066468 9550025 9763663 9829943 9848669 9870497 10053661 10062915 10241212 10392131 10406927 10509613 10512814 10630068 10641935 10737102 10760542 10894034 10899398 10996584 10998264 11006600 11258974 11417656 11550299 11695150 11787283 11935892 11992465 12038857 12060020 12066907 17.35 9.51 10.61 13.66 9.51 9.51 11.24 9.51 14.15 11.29 11.29 18.95 9.78 10.21 12.81 12.81 10.91 12.16 12.76 10.01 9.51 12.25 9.78 10.21 10.91 10.91 12.43 14.92 13.32 9.51 16.44 CG6209-RA CG18076-RC CG18076-RK CG6692-RC CG13350-RA CG8323-RA CG8367-RF CG8613-RA CG8787-RA intergenic CG12863-RA intergenic CG12858-RA CG10149-RA CG10209-RA CG10241-RA intergenic CG7449-RB intergenic intergenic CG11798-RC CG8169-RA CG8183-RB CG8205-RA CG30084-RG CG8355-RE CG8405-RA CG8416-RD CG8433-RA CG8435-RA CG8440-RB + + + + + + + + + + + + + + + + exon exon prom_exon promoter exon intronexon intron exon prom_exon OUT promoter OUT exon promoter promoter promoter OUT prom_exon OUT OUT intron intronexon intron intron intron intron intronexon prom_exon promoter promoter prom_exon 1443 34901 146 -235 604 979 913 1346 295 -4000 -625 -4000 2937 -1397 -1067 -1105 -4000 131 -4000 -4000 3716 315 2258 2396 7374 14309 -37 712 -1419 -1543 -149 chr2R chr2R chr2R chr2R chr2R chr2R chr2R chr2R chr2R chr2R chr2R chr2R chr2R chr2R chr2R chr2R chr2R chr2R chr2R chr2R chr2R chr2R chr2R chr2R chr2R chr2R chr2R chr2R chr2R chr2R chr2R 12083952 12105181 12107622 12222357 12467469 12494942 12495912 12576546 12618017 12900546 12914325 13150629 13280904 13323159 13379824 13405215 13435532 13479011 13759184 14028538 14044144 14164750 14190524 14260094 14390108 14418424 14420461 14519453 14741113 14859322 14875090 12084876 12105620 12108061 12224781 12468102 12495284 12497128 12576791 12618359 12900791 12916025 13150971 13281343 13323404 13380069 13405654 13435874 13479935 13759429 14028783 14046201 14165384 14190963 14261115 14390353 14418863 14420706 14519698 14741649 14860117 14875432 13.55 13.66 12.44 15.85 11.23 11.29 12.75 9.51 12.81 9.51 20.58 9.78 10.01 9.51 9.51 13.66 9.78 12.15 10.21 10.21 17.13 15.88 11.23 18.48 9.51 15.23 9.51 9.51 13.26 11.24 9.78 CG8446-RD CG8448-RD CG8448-RD CG4311-RA CG5072-RB CG5065-RA CG5065-RA CG30463-RD CG30463-RD CG15609-RD CG9635-RE intergenic CG10939-RA CG6542-RB CG30103-RA CG11419-RA CG4903-RB CG30105-RA CG5784-RD CG5119-RD CG5738-RC CG33198-RA CG14505-RB intergenic CG5224-RA CG10924-RB CG10924-RB CG5482-RA CG18190-RB CG15107-RA CG15105-RC + + + + + + + + + + + + + + + + + exonintron intron intron prom_exon prom_exon prom_exon intron intron intron intronexon prom_exon OUT promoter intron promoter intronexon exon intronexon intronexon promoter prom_exon exonintron exon OUT promoter promoter exon promoter promoter prom_exon exonintron 509 3900 1459 -25 157 -61 1346 42220 701 445 430 -4000 -976 9161 -1319 253 375 480 208 -196 271 37 738 -4000 -883 -1268 671 -172 -887 223 416 chr2R chr2R chr2R chr2R chr2R chr2R chr2R chr2R chr2R chr2R chr2R chr2R chr2R chr2R chr2R chr2R chr2R chr2R chr2R chr2R chr2R chr2R chr2R chr2R chr2R chr2R chr2R chr2R chr2R chr2R chr2R 15024491 15029777 15066844 15140266 15180434 15244406 15249547 15251002 15284496 15311648 15337615 15343773 15796673 16144548 16491135 16883608 17030367 17047732 17056957 17271996 17422439 17961272 17966890 18099841 18193925 18261605 18286391 18453814 18530077 18684862 18811350 15024930 15030972 15067671 15140608 15180996 15244845 15249986 15252605 15284742 15311990 15338054 15344309 15797015 16144890 16491477 16885202 17030612 17047977 17057978 17273405 17423174 17961517 17967620 18100844 18194170 18262583 18286830 18454059 18530904 18687644 18811692 11.23 19.54 12.8 11.29 12.25 11.23 13.66 11.65 9.51 11.29 15.23 14.57 9.78 12.81 9.78 19.48 9.51 9.51 12.16 19.13 9.78 9.51 10.01 12.99 10.21 15.19 11.23 9.51 10.78 15.74 11.29 CG15118-RA CG15112-RD CG7097-RB CG33453-RA CG7417-RA CG11961-RB CG10051-RA CG10051-RA CG10460-RA CG9325-RE CG9277-RA CG7753-RA intergenic CG9204-RC CG13425-RD CG10543-RA CG30388-RA CG30389-RA CG4279-RA CG10795-RA CG10079-RA CG11474-RB CG6562-RB CG5709-RA CG3413-RA CG10955-RA CG3624-RA CG12489-RA CG4414-RA CG3612-RA CG3820-RA + + + + + + + + + + + + + + + - prom_exon exonintron exonintron exonintron intron promoter promoter intronexon promoter promoter promoter exon OUT prom_exon intron prom_exon promoter intronexon intronexon promoter intron promoter promoter prom_exon intron promoter intron exon intronexon intronexon exon -28 1225 999 253 643 -609 -1382 654 -354 -220 -758 342 -4000 167 815 260 -422 195 682 -854 12297 -446 -420 -2 3407 -502 2950 26536 929 -305 734 chr2R chr2R chr2R chr2R chr2R chr2R chr2R chr2R chr2R chr2R chr2R chr2R chr2R chr2R chr2R chr2R chr2R chr2R chr2R chr2R chr2R chr2R chr2R chr2R chr2R chr2R chr2R chr2R chr2R chr2R chr2R 18812417 18864826 18881519 18931466 18965517 18968136 19088735 19091065 19128743 19131156 19237986 19631898 19633259 19759275 19820610 19830220 19855659 19923078 19950401 19953218 19978637 19985427 20049830 20315317 20414664 20462169 20549354 20552073 20573213 20666802 20669615 18813341 18865071 18881764 18932035 18966247 18968575 19089562 19093850 19129085 19132177 19238231 19632534 19633504 19760199 19821243 19830465 19857456 19923323 19951616 19953463 19978882 19987318 20050366 20315787 20414909 20462608 20550472 20552706 20574525 20667241 20669860 14.63 9.51 9.51 14.23 11.36 11.23 9.78 18.92 11.29 13.26 9.51 14.15 9.51 13.87 14.15 11.61 16.89 9.51 15.02 9.51 9.51 13.7 15.59 10.01 9.51 10.01 12.15 13.02 11.55 12.44 9.51 CG30193-RG intergenic CG9896-RA CG2956-RA CG9882-RB CG30189-RA CG34371-RA CG34371-RA intergenic CG13549-RB CG34210-RA CG4051-RB CG4051-RB CG5575-RA CG3725-RF CG2835-RA CG10904-RA CG3167-RA CG3204-RA intergenic CG3231-RA CG4012-RA CG3328-RA CG42310-RD CG30169-RA CG3522-RA CG3663-RA CG3683-RC CG4859-RC CG12196-RA CG16912-RA + + + + + + + + + + + + + + + + + - prom_exon OUT exon promoter exon exon intron prom_exon OUT intronexon promoter exonintron intron intron prom_exon exonintron intronexon exon prom_exon OUT exon prom_exon prom_exon intronexon intronexon intronexon exonintron intronexon intron exon intronexon 267 -4000 4764 -1879 677 272 2345 -963 -4000 743 -997 2132 966 1940 132 279 1034 1469 433 -4000 4631 -215 86 358 1064 289 867 442 1028 415 1280 chr2R chr2R chr2R chr2R chr2R chr2RHet chr2RHet chr2RHet chr2RHet chr2RHet chr3L chr3L chr3L chr3L chr3L chr3L chr3L chr3L chr3L chr3L chr3L chr3L chr3L chr3L chr3L chr3L chr3L chr3L chr3L chr3L chr3L 20683838 20760291 20826151 20898038 20969830 372993 392747 1563879 1972690 3178980 74831 137771 176093 177460 246580 342157 346764 504561 505541 534109 540135 543821 549377 565039 605835 629282 681444 711255 726359 747404 841315 20684859 20760924 20826493 20898962 20970175 373238 393016 1564124 1972935 3179419 75076 138695 176832 177705 247019 343081 347203 504903 506368 534451 540380 544163 550010 565478 606177 629527 682368 712761 726992 749201 841578 15.67 13.89 11.29 10.42 9.78 12.07 11.61 9.51 9.51 11.23 9.51 10.23 13.89 9.51 12.44 11.45 13.66 12.81 11.29 11.29 9.51 12.81 12.25 16.44 11.29 13.56 12.13 16.44 15.02 13.82 9.51 CG2917-RA CG16896-RA CG3760-RB CG15792-RB CG2679-RB CG41276-RA CG40191-RB intergenic intergenic CG40084-RA CG13405-RA CG1210-RC CG7049-RA CG7047-RB CG32346-RB CG1228-RB CG6936-RB CG17046-RB CG17046-RB CG17046-RB CG17046-RB CG17090-RB CG17090-RA CG17090-RA CG3200-RA intergenic CG3386-RA CG13896-RB intergenic CG1007-RA CG13902-RA + + + + + + + + + + + + + - intronexon exon exonintron intronexon intron prom_exon exonintron OUT OUT intronexon exon intron prom_exon exon prom_exon intron prom_exon intron exonintron intron prom_exon intron intron intron intron OUT prom_exon prom_exon OUT promoter prom_exon 578 1812 461 496 1840 -23 1853 -4000 -4000 440 312 5501 -236 1046 101 14499 -74 35472 34249 5924 -53 923 3623 19188 552 -4000 287 -158 -4000 -1102 -85 chr3L chr3L chr3L chr3L chr3L chr3L chr3L chr3L chr3L chr3L chr3L chr3L chr3L chr3L chr3L chr3L chr3L chr3L chr3L chr3L chr3L chr3L chr3L chr3L chr3L chr3L chr3L chr3L chr3L chr3L chr3L 959302 965966 968100 1092830 1093897 1206774 1349251 1365424 1366879 1655374 1665622 1717585 1883754 1966398 2151540 2243995 2362713 2373664 2500101 2575667 2635334 2776398 2824622 2834021 2851846 2867220 3060784 3143336 3179121 3224224 3225627 959547 966405 968733 1093075 1094142 1208862 1350466 1366154 1367318 1655619 1665964 1717830 1885357 1966643 2152561 2244337 2362958 2374103 2500346 2576231 2636221 2776934 2824964 2834460 2852772 2867659 3061126 3144908 3179463 3224566 3226155 9.51 13.98 10.23 9.51 9.51 15.01 11.09 12.88 10.01 9.51 9.78 9.51 20.5 9.51 11.36 11.7 9.51 10.01 9.51 14.27 13.58 12.25 12.81 9.51 16.37 12.44 9.78 11.68 11.29 9.78 12.04 CG1086-RB CG1086-RB CG1086-RB CG9097-RB CG9097-RB CG1179-RA CG9181-RD CG9181-RC CG9181-RC CG7971-RE CG7974-RA CG2086-RA CG18315-RA CG1140-RA CG33484-RC CG32301-RA intergenic CG9004-RA CG16758-RF CG16973-RC CG1244-RD CG1241-RA intergenic intergenic CG9973-RB CG9973-RB CG32486-RD CG1291-RA CG12734-RA CG11505-RA CG11505-RB + + + + + + + + + + + + + + + + + promoter intron intron intron intron prom_exon prom_exon intron intron intronexon exon exon prom_exon exon promoter promoter OUT prom_exon exon intron prom_exon exon OUT OUT intron intron intron prom_exon exonintron promoter prom_exon -236 6524 8755 8136 7069 448 -316 59190 57880 9273 651 13385 329 2051 -1961 -363 -4000 157 2591 10591 16 2288 -4000 -4000 19401 4270 9884 313 359 -442 -161 chr3L chr3L chr3L chr3L chr3L chr3L chr3L chr3L chr3L chr3L chr3L chr3L chr3L chr3L chr3L chr3L chr3L chr3L chr3L chr3L chr3L chr3L chr3L chr3L chr3L chr3L chr3L chr3L chr3L chr3L chr3L 3303762 3308520 3371782 3374110 3375662 3418003 3458970 3478477 3616468 3897135 4104838 4118242 4220361 4233726 4283837 4314035 4438437 4543124 4625508 4805142 4825870 5007048 5146672 5349648 5350815 5360511 5530605 5600572 5613305 5958054 6186641 3304007 3308959 3372221 3374549 3376101 3418927 3459215 3478819 3617101 3897380 4105180 4118487 4220606 4234068 4285059 4314280 4438682 4544630 4626044 4806260 4826309 5007293 5147014 5350090 5351254 5360756 5530850 5600817 5613647 5958315 6187177 9.51 9.51 10.01 10.01 12.44 17.55 13.47 9.78 15.02 9.51 12.81 9.51 9.51 9.78 11.45 9.51 10.91 12.39 12.25 14.35 9.78 9.51 11.29 12.44 13.66 9.51 12.77 9.51 9.78 9.51 14.62 CG17723-RD CG17723-RE CG12076-RB CG12010-RB CG12012-RA CG1921-RB CG10840-RB intergenic CG10357-RC CG14977-RA CG14991-RA CG14996-RB CG1332-RA CG15009-RA CG1316-RA CG32251-RA intergenic CG11357-RA CG7524-RC CG7509-RA CG7479-RA intergenic CG4659-RA CG10645-RC CG10642-RA CG10635-RA CG13285-RA CG12756-RA intergenic intergenic CG7398-RC + + + + + + + + + + + + + + + + + + + exon intron exon prom_exon promoter promoter exon OUT exonintron intronexon exon intron intron intron intronexon exon OUT intron intronexon prom_exon intronexon OUT intronexon promoter exon exon promoter exonintron OUT OUT intronexon 163 684 2164 22 -998 -538 1509 -4000 1403 358 1443 4058 3848 2250 594 523 -4000 1749 420 -427 232 -4000 1175 -846 1319 474 -1970 645 -4000 -4000 64 chr3L chr3L chr3L chr3L chr3L chr3L chr3L chr3L chr3L chr3L chr3L chr3L chr3L chr3L chr3L chr3L chr3L chr3L chr3L chr3L chr3L chr3L chr3L chr3L chr3L chr3L chr3L chr3L chr3L chr3L chr3L 6257330 6489090 6690792 6737890 6963372 7111307 7124128 7127620 7341421 7342585 7352994 7377544 7647850 7857610 8049967 8103609 8120381 8292779 8301071 8334747 8398796 8502443 8506500 9195502 9402846 9422629 9440142 9445294 9452961 9469329 9514309 6258060 6489670 6691231 6738232 6963714 7111552 7124373 7127982 7341957 7343024 7353336 7377789 7648365 7858243 8050406 8103951 8120723 8293353 8301704 8334992 8399138 8502785 8508394 9196620 9404100 9422971 9440387 9445636 9453497 9469671 9514554 13.89 15.54 11.23 11.29 9.78 10.91 9.51 14.26 11.24 12.44 12.34 9.51 10.85 13.02 11.23 12.81 9.78 13.22 10.23 9.51 11.29 11.29 13.92 18.27 11.59 11.29 9.51 9.78 15.59 9.78 9.51 CG10160-RA CG8339-RA CG10121-RA CG32393-RA CG9953-RA CG33556-RA CG8628-RA CG8624-RB CG8593-RA CG8593-RA CG8588-RF CG8571-RA CG7492-RA CG17888-RF CG7574-RA CG7927-RA CG7528-RA CG7197-RA CG7188-RB CG7083-RA CG13667-RB CG6694-RA CG6683-RA CG4484-RA CG4022-RA CG3922-RB CG3529-RB CG32038-RA CG3434-RA CG3431-RA intergenic + + + + + + + + + + + + + + promoter exonintron intron promoter exon intronexon intronexon exon exonintron intron intronexon intronexon promoter intron intron intronexon intronexon prom_exon exonintron exon exon exon prom_exon intronexon prom_exon prom_exon exonintron intronexon exon exon OUT -1902 551 5586 -1812 833 23512 277 184 275 1390 198 2714 -262 2545 1624 418 367 -169 674 948 414 233 544 2539 458 117 290 506 645 573 -4000 chr3L chr3L chr3L chr3L chr3L chr3L chr3L chr3L chr3L chr3L chr3L chr3L chr3L chr3L chr3L chr3L chr3L chr3L chr3L chr3L chr3L chr3L chr3L chr3L chr3L chr3L chr3L chr3L chr3L chr3L chr3L 9846166 10313964 10334899 10656431 10658204 10659368 10674184 10690586 10736595 10881656 11001860 11040562 11289992 11296631 11329596 11417039 11516542 11911125 11995769 11996980 12049537 12059400 12131789 12493760 12494768 12513516 12527060 12639121 12645332 12742264 12748214 9847769 10314826 10335144 10656870 10658546 10659904 10675119 10691410 10736867 10881901 11002978 11041195 11290722 11296973 11329841 11417284 11516787 11911758 11996305 11997419 12050170 12060227 12132228 12494199 12496565 12513761 12527790 12639657 12645771 12743964 12748653 16.6 14.82 9.51 11.23 9.78 11.94 12.39 13.44 9.51 9.51 13.55 18.13 10.01 11.29 10.21 9.51 9.51 16.44 14.57 13.28 11.23 12.88 10.43 10.01 17.11 9.51 10.23 17.86 12.44 17.14 10.01 CG6721-RB intergenic intergenic CG32068-RB CG32067-RB CG32067-RB CG32067-RB CG6449-RA intergenic CG7941-RA CG12296-RA CG6327-RB intergenic intergenic intergenic CG7560-RA CG6128-RA intergenic CG5684-RC CG6928-RA CG32096-RD CG32096-RB CG6811-RA CG10638-RA CG10681-RA intergenic CG10688-RA CG32111-RA intergenic CG5433-RA CG32113-RB + + + + + + + + + + + + + + + + + + + + + intronexon OUT OUT exonintron exonintron intron intron promoter OUT promoter prom_exon promoter OUT OUT OUT promoter promoter OUT prom_exon promoter prom_exon promoter prom_exon intron exonintron OUT prom_exon exon OUT prom_exon intronexon 1411 -4000 -4000 162 533 1794 16809 -1024 -4000 -1316 -495 -1140 -4000 -4000 -4000 -1087 -851 -4000 -24 -292 -309 -1854 36 431 962 -4000 -264 18354 -4000 42 188 chr3L chr3L chr3L chr3L chr3L chr3L chr3L chr3L chr3L chr3L chr3L chr3L chr3L chr3L chr3L chr3L chr3L chr3L chr3L chr3L chr3L chr3L chr3L chr3L chr3L chr3L chr3L chr3L chr3L chr3L chr3L 12797435 12798815 12820644 13222380 13472924 13491001 13506353 13995728 14185192 14202467 14231020 14266261 14267539 14505583 14783487 15077769 15199966 15207677 15251648 15450317 15501996 15524255 15634461 15721993 15808993 16040581 16094234 16105523 16157147 16197835 16222809 12797777 12799448 12820889 13222625 13473169 13491343 13507083 13996167 14185631 14202712 14231293 14266797 14267983 14505925 14783829 15078168 15200405 15208066 15251893 15450659 15502435 15524500 15635094 15722432 15809335 16041020 16096031 16105962 16157392 16198080 16223345 10.3 11.29 9.51 9.51 9.51 11.29 18.11 12.44 11.23 9.51 9.51 14.27 15.23 11.29 11.29 15.01 15.23 13.34 9.51 12.81 11.23 9.51 12.25 15.23 11.29 12.44 13.26 10.01 9.51 9.51 15.59 CG10967-RA CG11006-RB CG10960-RA CG11282-RA CG32130-RB CG10741-RA CG10743-RA CG9007-RA CG33991-RA CG33991-RB CG7906-RA CG17697-RB CG17697-RA CG42230-RC CG9425-RA CG33957-RB CG6888-RA intergenic intergenic intergenic CG17962-RA CG33983-RA CG42334-RC CG17943-RA CG6151-RA CG12284-RA CG5414-RA CG5215-RA intergenic intergenic CG5027-RA + + + + + + + + + + + + + + + + + + + + + intronexon exonintron intronexon intron promoter intron intronexon intron intron intron intronexon promoter exon exon promoter promoter promoter OUT OUT OUT prom_exon promoter intron promoter exonintron promoter intronexon promoter OUT OUT exon 608 139 164 714 -496 2446 260 699 1435 4058 1333 -917 287 594 -1572 -241 -757 -4000 -4000 -4000 55 -2047 6059 -689 345 -863 1683 -254 -4000 -4000 872 chr3L chr3L chr3L chr3L chr3L chr3L chr3L chr3L chr3L chr3L chr3L chr3L chr3L chr3L chr3L chr3L chr3L chr3L chr3L chr3L chr3L chr3L chr3L chr3L chr3L chr3L chr3L chr3L chr3L chr3L chr3L 16225138 16463156 16471658 16486331 16578261 16705346 16771697 16774299 16775948 16777112 16795182 16811117 17215387 17458050 17646286 17661650 17904305 17955620 18226838 18475052 18622254 18807851 18899434 18941961 19029282 19072287 19078398 19079368 19087463 19089956 19252952 16225674 16463886 16472000 16486964 16578991 16705979 16773712 16775320 16776484 16778327 16795527 16811362 17215632 17458295 17646725 17662778 17904744 17956641 18227180 18475297 18622596 18808290 18899679 18942400 19029527 19073017 19078643 19079904 19087805 19090298 19253779 13.26 13.89 11.29 16.18 10.61 11.29 14.48 12.6 13.26 12.88 11.29 9.51 9.51 9.51 15.23 12.88 10.01 12.13 11.29 9.51 11.29 12.44 9.51 12.76 9.51 17.35 9.51 16.9 9.78 9.78 16.77 CG13072-RA CG4531-RA CG4531-RA CG32158-RD CG4169-RA CG9695-RA CG13025-RA CG9706-RA CG9706-RA CG9706-RB CG9674-RA CG9710-RA CG32169-RA CG7603-RA CG32177-RA CG34251-RA CG5290-RA CG8127-RD intergenic intergenic CG6896-RA intergenic CG6841-RA CG6836-RA CG11614-RA CG14080-RB CG14080-RB CG14080-RB CG6818-RA CG10424-RA CG9655-RC + + + + + + + + + + + + + + + - promoter intronexon intron exon intronexon promoter prom_exon promoter intronexon intronexon promoter intron intron promoter intron promoter intronexon promoter OUT OUT intron OUT exon promoter intron intron intronexon prom_exon exon exon prom_exon -274 13280 4972 1720 1403 -578 110 -1336 70 1364 -2065 9718 15800 -875 870 -2507 1132 -1216 -4000 -4000 3365 -4000 1083 -1550 9026 6870 1001 -114 1863 685 413 chr3L chr3L chr3L chr3L chr3L chr3L chr3L chr3L chr3L chr3L chr3L chr3L chr3L chr3L chr3L chr3L chr3L chr3L chr3L chr3L chr3L chr3L chr3L chr3L chr3L chr3L chr3L chr3L chr3L chr3L chr3L 19344283 19688546 19691876 19762104 19828046 19900948 19915541 19921939 19996125 19999357 20004595 20341605 20391896 20511576 20763662 20903245 21042898 21310911 21476871 21509619 21674695 21825666 22065040 22370128 22374008 22390445 22437214 22566397 22764795 22862310 22864347 19344722 19689551 19692121 19762349 19828388 19902745 19916368 19922659 19996758 19999990 20004840 20342335 20392238 20511918 20764489 20903878 21043434 21311156 21477310 21510058 21675037 21825911 22065285 22370373 22374778 22390690 22437653 22566642 22765137 22863719 22865853 15.65 12.85 9.51 9.51 12.81 14.48 19 12.19 15.02 17.01 9.51 19.09 12.81 11.29 12.12 16.14 16.9 9.51 14.3 11.23 12.81 12.07 13.47 9.51 13.32 9.51 12.44 9.51 9.78 13.55 13.27 CG32206-RB CG8756-RB intergenic CG8742-RA CG32221-RA CG32217-RA CG8013-RB CG7823-RA CG7668-RB CG7749-RB CG7749-RB CG5605-RA CG5408-RA CG5059-RA CG4042-RA intergenic CG32434-RB CG32443-RA intergenic CG7597-RB CG11248-RA CG7421-RB CG7139-RA CG5723-RB CG5723-RB CG5723-RB intergenic intergenic CG32451-RA CG8385-RC CG8385-RH + + + + + + + + + + + + + + + + - intron promoter OUT intron exon prom_exon prom_exon exonintron intronexon promoter exon exonintron intron intron prom_exon OUT intron prom_exon OUT exonintron exon prom_exon promoter intron intron intron OUT OUT promoter exonintron prom_exon 61489 -717 -4000 21914 437 638 352 393 584 -2260 2783 479 2641 785 147 -4000 15528 42 -4000 424 1663 -55 -208 30736 26594 10419 -4000 -4000 -1671 1138 57 chr3L chr3L chr3L chr3L chr3L chr3LHet chr3R chr3R chr3R chr3R chr3R chr3R chr3R chr3R chr3R chr3R chr3R chr3R chr3R chr3R chr3R chr3R chr3R chr3R chr3R chr3R chr3R chr3R chr3R chr3R chr3R 22870691 22888223 23087666 23088830 24021859 605486 44998 279247 662127 708038 735238 737395 805294 813211 913224 914970 936577 976295 1076007 1417669 1425244 1426452 1427810 1494603 1559358 1561104 1618691 1685710 1952170 1982033 1996254 22872922 22888468 23088105 23089366 24022104 605925 45340 279589 662372 708380 735580 737640 805539 813456 913663 915312 937210 976637 1076449 1418205 1425489 1426697 1428152 1496236 1559603 1561349 1618936 1685955 1952415 1982472 1996499 20.56 9.51 10.01 16.12 9.51 15.23 11.29 13.34 9.51 14.26 9.78 9.51 9.51 9.51 12.44 12.81 17.01 13.34 11.23 15.59 9.51 9.51 12.81 17.28 9.51 9.51 9.51 9.51 9.51 13.66 10.91 CG10712-RC intergenic CG17521-RD CG17521-RC CG40045-RA CG41623-RA CG31516-RA CG31522-RB intergenic intergenic CG31536-RE CG31536-RC intergenic CG2022-RA CG2530-RA intergenic intergenic CG12591-RA CG12163-RB CG1088-RA CG2922-RE CG2922-RC CG1427-RC CG1347-RB CG1239-RA CG2100-RA CG1218-RA CG2017-RE intergenic CG31559-RA intergenic + + + + + + + + + + + + + + + + + + prom_exon OUT intronexon promoter intron promoter exon promoter OUT OUT promoter intron OUT intron promoter OUT OUT prom_exon intron exonintron prom_exon prom_exon exon prom_exon intronexon exon exon exon OUT exon OUT 57 -4000 681 -529 361 -514 683 -382 -4000 -4000 -868 1222 -4000 23419 -1035 -4000 -4000 -163 1240 452 -54 -106 827 -14 218 891 1206 1186 -4000 696 -4000 chr3R chr3R chr3R chr3R chr3R chr3R chr3R chr3R chr3R chr3R chr3R chr3R chr3R chr3R chr3R chr3R chr3R chr3R chr3R chr3R chr3R chr3R chr3R chr3R chr3R chr3R chr3R chr3R chr3R chr3R chr3R 2031408 2206360 2228223 2718376 2737923 2915431 2918503 3012764 3071622 3265355 3605209 3635159 3711559 3733317 3940029 3942713 3949021 3952707 4058994 4167822 4182311 4487074 4552720 4574832 4634309 4635578 4672436 4689076 4769818 4839233 4872790 2031847 2206702 2228662 2718940 2738362 2915681 2918748 3013300 3071964 3265697 3605648 3636627 3712712 3733659 3940468 3943055 3949654 3953825 4060306 4169522 4182556 4487319 4552965 4575077 4634756 4636696 4673368 4689521 4770063 4842097 4873520 11.23 12.81 15.23 13.96 10.21 9.51 9.51 14.62 11.29 12.34 11.23 14.11 19.44 9.78 10.01 13.34 17.01 18.27 12.32 14.93 9.51 9.51 9.51 9.51 10.01 10.61 16.58 14.08 9.51 20.61 12.16 CG15589-RA CG10281-RA CG1021-RH intergenic CG1028-RF intergenic CG14612-RA CG2520-RA CG1234-RA CG14598-RA intergenic CG2993-RA CG17816-RE CG2670-RB CG7850-RA CG7850-RA CG7878-RA CG7891-RA CG7602-RA CG9601-RA CG7954-RA CG9748-RA CG8159-RA CG8223-RA CG9837-RA CG9837-RA CG31349-RC CG9731-RA CG11964-RA CG11984-RA CG11992-RC + + + + + + + + + + + + + + + + + - intronexon intronexon intron OUT intron OUT promoter exonintron exon prom_exon OUT prom_exon prom_exon intronexon intron intron intronexon intronexon intronexon prom_exon promoter promoter intronexon intron intronexon promoter promoter promoter exon prom_exon prom_exon 7093 351 3170 -4000 20419 -4000 -1219 314 896 39 -4000 -183 299 127 9192 11828 917 931 369 547 -254 -713 267 1427 1000 -604 -892 -794 785 -116 87 chr3R chr3R chr3R chr3R chr3R chr3R chr3R chr3R chr3R chr3R chr3R chr3R chr3R chr3R chr3R chr3R chr3R chr3R chr3R chr3R chr3R chr3R chr3R chr3R chr3R chr3R chr3R chr3R chr3R chr3R chr3R 4878955 5163936 5165779 5167585 5171762 5172926 5175233 5177916 5206434 5226253 5338318 5456134 5526425 5530512 5580791 5871752 5905950 5913039 5924252 6012279 6091497 6155407 6176111 6213203 6440362 6519266 6522437 6523989 6641233 6676795 6998719 4880574 5165151 5166024 5169000 5172104 5173559 5177131 5178258 5206679 5226498 5339727 5456476 5527349 5530859 5581133 5872094 5906680 5913963 5924594 6012621 6091936 6155749 6177908 6213545 6440607 6519511 6523361 6524428 6641769 6679555 6999158 12.16 12.13 9.51 14.14 11.29 10.42 15.82 9.78 9.51 9.51 13.77 12.81 12.13 9.78 9.78 9.78 11.24 12.15 11.29 11.29 12.44 11.29 15.94 9.78 9.51 9.51 12.76 12.44 14.57 17.42 10.01 CG11033-RA intergenic CG33936-RA CG33936-RA CG33936-RA CG33936-RA CG33936-RA CG33936-RA CG8874-RA CG9354-RA CG8161-RA CG9429-RA CG31352-RA CG31352-RA CG16908-RA CG3910-RA intergenic intergenic intergenic CG12814-RB CG11870-RD CG6303-RA CG4029-RA CG17100-RA CG17117-RC CG33676-RA CG14683-RB CG4067-RA CG4089-RA CG4565-RB CG6644-RA + + + + + + + + + + + + + + + + + + + + + - exonintron OUT promoter exonintron intron intron intron intron intron exon intronexon intronexon intron intronexon promoter exonintron OUT OUT OUT intron intron exonintron exonintron promoter promoter exon intronexon promoter exon exonintron promoter 1525 -4000 -1689 701 4342 5651 8591 10496 13708 548 -44 302 4278 479 -659 626 -4000 -4000 -4000 1292 1689 1493 1104 -610 -511 6724 528 -1167 489 -270 -552 chr3R chr3R chr3R chr3R chr3R chr3R chr3R chr3R chr3R chr3R chr3R chr3R chr3R chr3R chr3R chr3R chr3R chr3R chr3R chr3R chr3R chr3R chr3R chr3R chr3R chr3R chr3R chr3R chr3R chr3R chr3R 7035969 7062286 7069380 7178203 7301825 7407735 7437254 7439776 7566941 7935444 8104470 8168442 8268834 8518108 8838098 8903626 8904538 9058523 9183170 9509792 9856742 10150978 10217019 10400490 10450337 10476052 10479065 10920010 11022388 11172796 11618724 7036214 7062725 7069722 7178933 7302167 7407980 7438372 7441185 7567671 7935689 8104715 8168700 8269661 8518547 8839225 8903871 8905074 9058865 9183513 9510879 9857181 10151514 10217721 10400832 10450679 10476588 10479601 10921225 11022924 11173041 11619066 9.51 11.23 11.29 16.14 11.82 9.51 11.24 13.37 14.4 9.51 9.51 9.51 12.16 10.01 12.2 9.51 14.62 9.78 12.81 11.63 9.51 12.25 18.43 9.78 11.29 12.25 12.25 12.15 14.57 9.51 11.29 CG4800-RA CG31441-RA CG17734-RA CG6715-RA intergenic CG5344-RA CG31363-RA CG31363-RA CG6920-RA CG31361-RB CG11502-RC intergenic CG5887-RB CG31347-RA CG7583-RC CG7771-RA intergenic CG17907-RA intergenic CG9351-RB CG12537-RB CG8538-RB CG34389-RA CG7987-RB CG7904-RA CG7832-RA CG7832-RA CG6966-RB CG4196-RB CG31392-RA CG18505-RA + + + + + + + + + + + + + + + + prom_exon exon prom_exon promoter OUT intron intron intron prom_exon intronexon intron OUT prom_exon prom_exon intron exon OUT exonintron OUT exonintron intron exon intronexon exonintron intron intron intron intronexon prom_exon promoter intronexon 117 498 147 -2201 -4000 557 7843 5175 199 11759 20122 -4000 -55 -8 1175 5625 -4000 25896 -4000 656 815 1158 13794 909 913 5103 2090 715 12 -921 435 chr3R chr3R chr3R chr3R chr3R chr3R chr3R chr3R chr3R chr3R chr3R chr3R chr3R chr3R chr3R chr3R chr3R chr3R chr3R chr3R chr3R chr3R chr3R chr3R chr3R chr3R chr3R chr3R chr3R chr3R chr3R 11799771 11808576 11891880 12006128 12031000 12074900 12097889 12098812 12182181 12623731 12879760 12975586 13363988 13506201 13769125 13872038 13888963 13964156 13992355 14023994 14226853 14443480 14484902 14632328 14636159 14741730 15050809 15391308 15468861 15832536 16153765 11800404 11808821 11892319 12006567 12031480 12075145 12098134 12099547 12182426 12624655 12880491 12975831 13364330 13507836 13770049 13872477 13889208 13964401 13992697 14025536 14227098 14443725 14485632 14632573 14636598 14742169 15052024 15391747 15470191 15832781 16154010 18.13 9.51 11.23 10.01 13.6 9.51 9.51 18.37 9.51 12.15 12.88 9.51 14.26 16.06 11.24 13.66 10.21 9.51 11.29 15.27 9.51 9.51 18.37 9.51 11.23 15.23 13.72 9.78 15.86 9.51 9.51 CG18740-RA CG4261-RA CG10185-RA CG8927-RA CG4337-RB CG6889-RB CG12785-RA CG6963-RF CG10311-RA intergenic CG5201-RA CG12265-RA CG5824-RA CG18212-RG CG42457-RA CG7223-RC intergenic intergenic CG7217-RB CG7187-RA CG12333-RA CG7695-RA CG7697-RA CG18208-RA CG18208-RA CG17836-RB CG5269-RA CG34157-RD CG6213-RA CG4451-RA CG4360-RA + + + + + + + + + + + + + - promoter intronexon intronexon promoter promoter intron prom_exon exonintron intron OUT exonintron intronexon exon intronexon prom_exon exon OUT OUT promoter prom_exon exon promoter intronexon exon intron intron exonintron intron prom_exon intron promoter -1456 5697 1134 -393 -267 6482 112 421 429 -4000 397 293 1539 946 -241 2825 -4000 -4000 -283 552 1459 -397 154 42495 38567 1260 956 56546 608 1585 -155 chr3R chr3R chr3R chr3R chr3R chr3R chr3R chr3R chr3R chr3R chr3R chr3R chr3R chr3R chr3R chr3R chr3R chr3R chr3R chr3R chr3R chr3R chr3R chr3R chr3R chr3R chr3R chr3R chr3R chr3R chr3R 16417475 16762436 16775114 16952064 16954198 17049154 17095107 17174503 17308411 17312970 17345932 17454933 17456415 17457967 17486014 17602663 17959128 18110780 18127614 18192445 18200230 18236827 18271923 18359448 18448169 18985166 19040808 19082632 19738943 19741077 19748035 16417720 16762681 16775650 16953376 16954637 17049884 17095643 17175039 17308753 17313409 17347147 17455178 17456660 17458406 17486259 17604266 17960052 18111025 18127859 18192787 18201348 18237266 18272168 18359693 18448414 18985427 19041247 19082877 19739673 19741322 19748603 9.51 9.51 19.14 15.26 10.01 18.11 15.59 12.25 11.29 12.44 14.41 9.51 9.51 12.39 9.51 13.79 12.46 9.51 9.51 12.81 20.24 12.44 13.56 9.51 9.51 10.91 13.66 9.51 18.37 10.91 15.59 CG4159-RA CG31191-RA CG5670-RG CG3412-RA CG5793-RA CG5874-RA CG6056-RA CG16791-RA CG7922-RA CG7922-RA CG7956-RA CG6376-RA CG6376-RA CG6376-RA CG6376-RB CG13418-RA CG31163-RB CG31163-RB CG7084-RA CG5380-RA CG18596-RA CG42250-RD CG12499-RA CG33093-RA CG5248-RC CG4624-RA CG17894-RC CG4448-RA CG13598-RC CG13598-RC CG13598-RC + + + + + + + + + + + - exonintron intron intron prom_exon exonintron prom_exon exonintron exon intronexon exonintron prom_exon intron intron exon prom_exon prom_exon prom_exon intron intronexon intronexon promoter prom_exon exon promoter exon promoter intron exon exonintron intron intron 774 8693 947 482 972 94 424 535 536 5143 -122 3688 2206 557 -9 45 11 151323 2030 265 -877 -7 208 -1926 4043 -258 6655 1024 9387 7495 376 chr3R chr3R chr3R chr3R chr3R chr3R chr3R chr3R chr3R chr3R chr3R chr3R chr3R chr3R chr3R chr3R chr3R chr3R chr3R chr3R chr3R chr3R chr3R chr3R chr3R chr3R chr3R chr3R chr3R chr3R chr3R 19784903 19812848 19873769 19875612 19934258 19973994 20174604 20391006 20411802 20454179 20613299 20641535 20744214 20849741 20865042 20873772 20882719 20899963 21033158 21093001 21161245 21297832 21449499 22278066 22392820 22691515 22778535 22852535 22958953 23406169 24370148 19785245 19813093 19874693 19875857 19934794 19974433 20175043 20391348 20412338 20454715 20613544 20641780 20744847 20850374 20865869 20874696 20883061 20900208 21034470 21093246 21161684 21298077 21451196 22278408 22393259 22693506 22779168 22852974 22959198 23408063 24371152 11.29 9.51 11.29 9.51 14.27 11.23 13.66 12.81 14.57 12.25 9.51 9.51 10.01 11.24 11.36 12.76 9.78 9.51 12.8 9.51 12.44 10.21 14.04 9.78 12.44 17.86 13.02 13.66 9.51 22.09 15.77 CG5864-RA CG5902-RA CG5422-RD CG5991-RA CG33100-RA CG31133-RA CG6454-RD CG13624-RC CG34100-RA CG31127-RA CG5805-RA CG5808-RA CG11168-RA CG11781-RA CG11785-RA CG11790-RA CG34349-RA CG9996-RB CG10244-RA CG13656-RA CG11902-RA CG10772-RA CG4673-RB CG5447-RA CG5462-RH CG6386-RA CG6330-RA CG5811-RA CG6051-RB CG5643-RC CG12413-RA + + + + + + + + + + + + + + - intronexon intronexon prom_exon promoter prom_exon exon prom_exon intron intron intronexon promoter exon intronexon intronexon intronexon exonintron prom_exon intronexon prom_exon promoter exonintron intron prom_exon prom_exon intronexon prom_exon prom_exon promoter intron prom_exon prom_exon 699 576 -244 -775 145 431 -88 7039 686 1363 -279 1071 663 669 359 813 79 243 189 -1258 428 823 34 -17 30964 18 122 -884 17644 -119 -126 chr3R chr3R chr3R chr3R chr3R chr3R chr3R chr3R chr3R chr3R chr3R chr3R chr3R chr3R chr3R chr3R chr3R chr3R chr3R chr3R chr3R chr3R chr3R chr3R chr3R chr3R chr3R chr3R chr3R chr3R chr3R 24431416 24460388 24494785 24496822 24540632 24669959 24714572 24861351 24948894 25083361 25282500 25416987 25457938 25600961 25847842 26088900 26291233 26388899 26503162 26619565 26632013 26885043 26887080 27021681 27043943 27046615 27135460 27283007 27434513 27597010 27602953 24431758 24460924 24495030 24498634 24541071 24670204 24715698 24862081 24949624 25083897 25284301 25417232 25458183 25601206 25848189 26089145 26292545 26389629 26503407 26619907 26632355 26885773 26887325 27022023 27045158 27046860 27136809 27284125 27436116 27597643 27603392 9.78 17.25 9.51 16.99 12.44 9.51 14.06 10.01 14.4 14.57 16.22 9.51 9.51 9.51 11.29 9.51 17.73 12.88 9.51 11.29 11.82 12.88 9.51 11.29 14.76 9.51 14.55 14.58 12.8 11.29 13.66 CG9986-RA CG10011-RA CG33346-RA CG9989-RA CG9995-RA CG1451-RA CG42320-RS CG1957-RB CG11880-RB CG1395-RA CG11516-RC CG1906-RE CG18741-RA CG33956-RA CG7921-RA intergenic CG31022-RA CG1539-RA intergenic CG12072-RA CG12072-RA CG2048-RC CG2048-RA CG31004-RA CG1746-RB CG12054-RA CG34347-RB CG17998-RA CG11525-RC CG2135-RA CG1945-RC + + + + + + + + + + + + + + + + + + promoter prom_exon promoter exonintron exonintron3 intron exonintron exon prom_exon promoter prom_exon promoter exon intron prom_exon OUT prom_exon exonintron OUT exon prom_exon intron promoter promoter prom_exon intronexon promoter exonintron prom_exon prom_exon intron -271 129 -434 1271 18888 290 393 1137 122 -2127 110 -433 27645 2383 -35 -4000 116 372 -4000 12605 157 1087 -271 -368 228 312 -760 52596 268 248 417 chr4 chr4 chr4 chr4 chr4 chr4 chr4 chrU chrX chrX chrX chrX chrX chrX chrX chrX chrX chrX chrX chrX chrX chrX chrX chrX chrX chrX chrX chrX chrX chrX chrX 89126 90096 436167 680387 684446 979911 1052281 1182778 23787 139446 441084 485659 549292 660087 662027 736335 743802 792535 901573 903516 1061627 1121798 1170009 1212259 1215713 1407352 1776026 1793177 1802066 1832622 1904032 89468 90535 436897 681214 684691 980156 1052720 1183023 24420 141340 441329 485904 550701 660526 662369 737162 744338 792974 901821 904246 1062066 1122237 1170448 1212795 1215958 1407694 1776950 1793422 1802993 1832964 1905441 11.29 12.44 20.26 14.82 9.51 10.21 15.65 10.91 10.01 16.86 10.21 9.51 13.25 12.86 12.81 19 16.9 10.01 9.51 16.14 12.44 12.86 13.66 12.25 9.51 11.29 12.15 9.51 10.01 11.29 17.41 CG34403-RG CG34403-RA intergenic CG31992-RE CG1783-RA CG32016-RB CG11154-RA CG17691-RA CG00000-RB CG2995-RA CG7727-RA CG6172-RA CG13363-RA CG7434-RA CG16785-RA CG14635-RA CG42248-RD CG14632-RB intergenic CG14631-RA intergenic CG3638-RB CG11405-RA CG14622-RB CG14622-RB CG32810-RB CG3848-RD CG11579-RC CG3810-RB CG3857-RA CG4406-RA + + + + + + + + + + + + + + + + - promoter prom_exon OUT prom_exon intronexon promoter prom_exon intron prom_exon prom_exon intron exon prom_exon promoter promoter promoter intron intron OUT promoter OUT intron promoter intron intron exonintron intronexon intronexon prom_exon exon promoter -658 -37 -4000 -210 355 -939 61 4021 226 354 15555 707 78 -1134 -1862 -2120 34427 10099 -4000 -2186 -4000 7068 -1546 3862 553 432 7320 343 -226 1247 -1360 chrX chrX chrX chrX chrX chrX chrX chrX chrX chrX chrX chrX chrX chrX chrX chrX chrX chrX chrX chrX chrX chrX chrX chrX chrX chrX chrX chrX chrX chrX chrX 1906769 1935222 1951220 2188120 2197589 2200666 2230192 2233927 2352180 2357461 2359304 2440690 2483006 2556467 2582516 2608711 2682333 2684063 2689311 2692486 3067074 3068917 3237342 3465577 3665050 3705828 3728779 3735161 3737785 4002114 4011021 1907305 1936049 1951465 2188969 2198709 2201465 2230437 2234269 2354309 2358191 2360034 2441480 2483348 2556712 2582955 2608956 2682869 2685084 2691257 2692925 3068192 3070839 3239293 3465919 3665392 3706073 3729024 3735988 3738224 4002844 4011266 15.59 18.12 9.51 11.63 15.12 17.07 9.51 12.81 13.2 19.09 13.64 13.92 12.81 9.51 13.66 9.51 15.59 19.09 17.81 15.23 16.34 20.95 14.74 11.29 14.26 13.56 9.51 18.32 10.01 10.23 9.51 CG4399-RB CG4380-RA CG4290-RA CG2865-RA intergenic intergenic CG2845-RC CG2845-RB CG32796-RB CG32796-RB CG32796-RB CG33950-RF CG9659-RC CG2621-RD CG2647-RA CG2694-RC CG32795-RB CG32795-RC CG2759-RA CG2759-RA CG18508-RA CG4015-RA intergenic CG2875-RA CG34412-RB CG2904-RB CG2904-RA CG2904-RA CG2904-RC CG4944-RB CG4857-RB + + + + + + + + + + + + + + + + + intron prom_exon exon promoter OUT OUT intron prom_exon intron intron intron promoter exon intron exon prom_exon exonintron promoter prom_exon promoter prom_exon prom_exon OUT intronexon intron prom_exon promoter exonintron promoter intron prom_exon 681 -319 4605 -1765 -4000 -4000 2321 -60 10791 6210 4367 -1662 644 3786 3123 75 895 -598 215 -2206 -478 -247 -4000 1905 24026 -24 -1226 5446 -2105 1612 -58 chrX chrX chrX chrX chrX chrX chrX chrX chrX chrX chrX chrX chrX chrX chrX chrX chrX chrX chrX chrX chrX chrX chrX chrX chrX chrX chrX chrX chrX chrX chrX 4108302 4190901 4528369 4543523 4553760 4572199 4594764 4976556 4979258 5184146 5202860 5204315 5327417 5409473 5500030 5571314 5572284 5768330 5777109 5781679 5809634 5810507 5928891 5930152 6039360 6266512 6362338 6427803 6517010 6588313 6653846 4108935 4191257 4528711 4544738 4554005 4573807 4595009 4976874 4979600 5184618 5203105 5205661 5328244 5409878 5500372 5571656 5572529 5770515 5779550 5782118 5809879 5810946 5929524 5930494 6039605 6267339 6362583 6428694 6517255 6588558 6654285 15.88 10.83 11.29 12.88 9.51 19.22 12.07 12.23 11.29 11.27 9.51 12.97 14.15 10.3 11.29 9.78 10.21 21.79 16.54 12.44 9.51 12.44 12.6 12.81 13.56 10.01 10.21 10.01 9.51 9.51 12.44 intergenic intergenic CG12179-RA CG7035-RA CG3009-RA CG3000-RA CG7010-RA CG32767-RB CG6775-RF intergenic CG3319-RA CG3315-RA intergenic CG12730-RA CG4136-RA CG3171-RA CG3171-RA CG3025-RA CG16721-RA intergenic CG3011-RB CG3011-RA intergenic CG4336-RA CG15899-RB CG12217-RA CG42340-RC CG3929-RA CG3973-RA CG14442-RA CG14438-RB + + + + + + + + + + + + + + + OUT OUT exon intronexon exon prom_exon promoter intron promoter OUT prom_exon intronexon OUT promoter intronexon intron intron exon exonintron OUT promoter prom_exon OUT exon exon prom_exon exonintron prom_exon intron exon exonintron -4000 -4000 1475 77 6847 616 -1417 343 -436 -4000 -21 933 -4000 -1617 11896 2523 1601 1461 4439 -4000 -840 99 -4000 886 716 -51 55895 206 23035 579 296 chrX chrX chrX chrX chrX chrX chrX chrX chrX chrX chrX chrX chrX chrX chrX chrX chrX chrX chrX chrX chrX chrX chrX chrX chrX chrX chrX chrX chrX chrX chrX 6697048 6737570 6739843 6752288 6754786 6907435 6990148 7197199 7321899 7423896 7861590 7862678 7866702 7956578 7985808 8025126 8140047 8306529 8335231 8337186 8455497 8485681 8503756 8518710 8520398 8570692 8615316 8616737 8621441 8731921 8790368 6698360 6737815 6740282 6752681 6755360 6907680 6990781 7197638 7322144 7424335 7862029 7865664 7866947 7956823 7987270 8025371 8140292 8307356 8335476 8337975 8456033 8486731 8504292 8519731 8520740 8570937 8615917 8617079 8621686 8732362 8790710 14.15 9.51 9.78 13.34 11.24 9.51 10.42 10.01 10.21 10.01 12.44 15.65 9.51 9.51 11.36 9.51 9.51 11.36 9.51 13.67 16.9 13.13 13.26 11.36 11.82 10.91 11.65 11.29 9.51 9.78 11.29 CG4532-RF CG14435-RA CG4557-RA intergenic intergenic CG3032-RA CG18350-RE intergenic intergenic intergenic CG2212-RA CG32858-RA CG32858-RA CG1560-RA CG2257-RC CG10958-RA CG2151-RC intergenic CG12123-RA CG12123-RA CG11265-RC CG12737-RA intergenic intergenic intergenic CG12772-RA CG1789-RA intergenic intergenic intergenic CG10701-RF + + + + + + + + + + + + + + + + + + + + + + + - prom_exon exon exon OUT OUT exon intron OUT OUT OUT exon exonintron intron intron prom_exon promoter intronexon OUT intronexon promoter intron prom_exon OUT OUT OUT promoter exonintron OUT OUT OUT intron -15 260 1687 -4000 -4000 137 629 -4000 -4000 -4000 253 434 3087 1021 -396 -1189 1750 -4000 1020 -1206 653 121 -4000 -4000 -4000 -280 1027 -4000 -4000 -4000 1492 chrX chrX chrX chrX chrX chrX chrX chrX chrX chrX chrX chrX chrX chrX chrX chrX chrX chrX chrX chrX chrX chrX chrX chrX chrX chrX chrX chrX chrX chrX chrX 8800486 8882913 9058111 9141009 9387033 9477825 9494797 9580502 9902607 10061924 10280450 10349781 10366687 10385794 10441496 10489099 10624093 10679181 10726487 10772815 10838913 10841455 10987684 11029178 11048340 11197569 11219358 11377699 11506359 11702103 11749139 8802028 8883158 9058356 9141351 9387375 9478635 9495050 9580941 9904415 10062169 10280695 10350026 10367926 10386233 10442420 10491202 10624338 10680795 10726926 10773060 10839643 10841700 10988026 11029423 11048973 11197814 11219797 11377944 11507283 11702378 11749481 11.59 9.51 9.51 11.29 12.81 14.37 9.51 12.44 11.92 9.51 9.51 9.51 12.8 9.78 12.15 16.67 9.51 13.72 11.23 9.51 12.12 9.51 12.81 9.51 15.88 10.91 11.23 9.51 18.95 10.91 11.29 CG15352-RA CG10962-RA CG12218-RA CG12127-RA CG34339-RB CG3001-RA CG3002-RB intergenic CG33557-RA intergenic CG2096-RA CG32683-RA CG17255-RB CG34414-RI CG34414-RG CG2124-RA CG32676-RA CG1683-RB CG1664-RA CG1637-RC CG2174-RD CG2174-RD CG2061-RB CG1453-RC CG1938-RD CG34144-RA CG1657-RA CG1749-RA CG1703-RA CG4147-RB CG1886-RB + + + + + + + + + + + + + + + + + prom_exon intron intron exon intron promoter promoter OUT exonintron OUT exonintron promoter prom_exon exon promoter prom_exon intron intron intronexon promoter exon exon exon exon prom_exon promoter prom_exon exon exon promoter exon -490 59984 934 189 3017 -1687 -142 -4000 244 -4000 607 -975 290 1755 -1195 41 14722 925 14418 -1097 6797 9096 1094 1155 223 -1009 83 282 772 -1028 245 chrX chrX chrX chrX chrX chrX chrX chrX chrX chrX chrX chrX chrX chrX chrX chrX chrX chrX chrX chrX chrX chrX chrX chrX chrX chrX chrX chrX chrX chrX chrX 11797314 11884541 11922512 11927815 11929561 12096669 12366145 12449640 12497383 12916947 12985272 13005531 13178622 13252329 13265362 13280295 13316303 13397280 13459544 13474931 13518406 13576621 13640552 13783038 14100955 14123315 14473462 14562750 14732858 14915951 15488192 11797656 11884786 11922757 11928060 11930636 12096914 12367069 12449885 12497628 12917192 12985551 13006358 13179269 13252962 13269084 13280734 13316839 13397525 13459983 13475176 13519327 13576866 13641045 13784585 14101553 14123560 14474774 14562995 14733200 14916390 15488631 12.81 10.21 9.51 9.51 17.98 9.51 13.68 9.51 9.51 11.53 10.21 12.46 13.25 14.76 17.36 10.01 14.27 10.91 12.44 9.51 14.17 10.91 12.81 17.21 14.23 9.51 17.98 9.51 9.78 10.01 12.44 CG1559-RA CG18130-RB CG1490-RB CG1786-RA intergenic CG42338-RH CG42258-RD intergenic CG32654-RE CG2209-RA CG12244-RA CG12714-RB CG1770-RA CG10617-RA CG1640-RF CG1989-RB intergenic CG32635-RA CG32632-RC CG32632-RB CG11172-RA CG11158-RA CG10988-RA CG34346-RD CG32597-RB CG42271-RC CG14414-RC intergenic CG32590-RA CG32592-RA intergenic + + + + + + + + + + + + + + + + + + + exon intronexon exon exonintron OUT intron intron OUT intronexon exon exon exonintron intronexon promoter exonintron exon OUT intron intron intron prom_exon promoter promoter intron intron intronexon prom_exon OUT prom_exon intron3 OUT 1888 1663 426 1273 -4000 6990 907 -4000 7400 839 256 2524 408 -636 2159 912 -4000 57464 1907 4813 77 -195 -2110 77832 4207 4647 -522 -4000 135 41269 -4000 chrX chrX chrX chrX chrX chrX chrX chrX chrX chrX chrX chrX chrX chrX chrX chrX chrX chrX chrX chrX chrX chrX chrX chrX chrX chrX chrX chrX chrX chrX chrX 15545750 15653055 15682534 15689748 15695457 15724375 15728643 15752218 15783834 15833885 15883509 15892305 15956142 15957209 15998662 16284746 16484655 16493373 16504486 16558079 16781882 16970673 17193658 17207066 17239829 17296167 17425034 17427265 17451956 17530164 17590874 15545996 15653300 15682876 15690187 15695799 15724620 15729050 15752754 15785049 15834324 15884336 15892744 15956484 15958329 15999586 16285701 16484900 16493715 16504828 16558421 16782224 16971525 17194776 17207408 17240665 17296412 17426249 17427510 17452402 17530409 17591313 10.21 9.51 12.81 15.23 9.78 9.51 10.83 16.9 10.42 12.44 12.36 10.01 9.78 10.23 13.37 11.23 9.51 12.81 12.34 11.29 11.29 14.89 13.26 12.81 10.85 9.51 14.94 9.51 11.23 9.51 12.44 intergenic CG8948-RF CG8497-RA CG8974-RE CG8995-RA CG9012-RB CG9012-RB CG9045-RE CG15916-RA CG9126-RA CG9177-RG CG8939-RA CG12395-RA CG14948-RA CG42353-RB CG9984-RA CG9802-RA CG4453-RB CG18582-RA CG15865-RA CG4880-RA CG8949-RA CG8649-RC CG5488-RA intergenic CG5529-RA intergenic CG12432-RA intergenic CG5800-RA CG32556-RA + + + + + + + + + + + + + + - OUT promoter promoter prom_exon exonintron exon prom_exon promoter prom_exon intron intronexon exon exon exonintron prom_exon prom_exon exon exonintron prom_exon exon exon exonintron prom_exon promoter OUT exon OUT exon OUT prom_exon intron -4000 -271 -220 114 1330 4244 -104 -632 -189 363 417 1455 553 -4 -179 219 2684 189 -87 238 1191 814 437 -1376 -4000 4756 -4000 1263 -4000 -28 1465 chrX chrX chrX chrX chrX chrX chrX chrX chrX chrX chrX chrX chrX chrX chrX chrX chrX chrX chrX chrX chrX chrX chrX chrX chrX chrX chrX chrX chrX chrX chrX 17594876 17597750 17754209 17802577 18030935 18133779 18175591 18222140 18302337 18305706 18410247 18447936 18539552 18547681 18552032 18684396 18689233 18887325 18953189 19373533 19473534 19520004 19531267 19577448 19653551 19672668 19745337 19765632 19792342 19945701 20048586 17595121 17598286 17754551 17802919 18031762 18134024 18176325 18222482 18302582 18305951 18410783 18448181 18541074 18548120 18552277 18684641 18689575 18887570 18953434 19373778 19473779 19520443 19531926 19577693 19653990 19672913 19746843 19765877 19792685 19945946 20049219 9.51 13.26 9.78 9.78 12.74 9.51 10.01 12.81 9.51 10.21 14.27 9.51 19.76 15.23 9.51 9.51 11.29 9.51 9.51 9.51 9.51 13.66 11.89 9.51 11.23 10.21 19.66 9.51 12.81 9.51 10.23 CG8188-RB CG5884-RA CG7846-RA CG6842-RA CG5659-RC intergenic CG33542-RB CG6123-RA CG32549-RD CG32549-RD CG6335-RB CG6500-RA CG6606-RA CG6632-RA CG6551-RA CG7053-RA CG7088-RD CG32541-RA intergenic CG32531-RA CG14217-RD CG14212-RA CG12238-RA CG14226-RA CG12702-RA CG12701-RA CG11940-RA CG32529-RA CG32529-RC CG9570-RA CG9572-RA + + + + + + + + + + + + + + + exon exonintron exon intronexon prom_exon OUT intron exon intron promoter intron intron intron promoter intronexon promoter exon intron OUT exon intron exon intronexon prom_exon intronexon exon prom_exon intronexon intron exon intronexon 1995 657 460 1029 214 -4000 4693 27810 1708 -1660 1084 19361 1283 -776 368 -1181 1176 63056 -4000 253 169 457 788 -21 2585 3838 -6 3312 6293 497 6739 chrX chrX chrX chrX chrX chrX chrX chrX chrX chrX chrX chrX chrX chrX chrX chrX chrYHet chrYHet chrYHet 20126306 20267151 20279737 20335065 20395519 20529474 20924365 21166212 21225822 21290080 21500536 21844769 21857243 21882988 21889674 22381684 35064 64029 81565 20126745 20267687 20279982 20335310 20395958 20529719 20924804 21166457 21226164 21290325 21500975 21845111 21858652 21883330 21890016 22381931 35309 64274 83265 10.01 14.57 9.51 13.47 11.23 9.51 13.66 9.51 9.78 9.51 10.01 11.29 14.48 9.78 11.29 10.21 9.51 9.51 10.87 CG17065-RA CG11734-RB CG11734-RB CG32506-RB CG18492-RA CG1829-RA CG32513-RA CG1718-RA CG1391-RD intergenic CG17686-RF CG14621-RA CG14619-RE CG12576-RA CG14616-RJ intergenic CG17629-RA CG17629-RA CG17866-RB + + + + + + + + + + + + + + exonintron exon exon exonintron prom_exon exon promoter exon exon OUT exonintron promoter prom_exon intron intron OUT exon exon exonintron 1631 1915 14355 5008 214 786 -448 5054 3356 -4000 429 -1649 309 764 830 -4000 897 29862 1207 (B) CG bound by ISWI and whose expression changes in ISWI mutant Total Larvae at least x1.5 fold [Induced (26%) / Repressed (74%) n=251/537] CT32761.A CT25670.A CT33047.A CT34378.A GENE DESCRIPTION || BcDNA:AT11049 || 61A6 || 61A6 || 1787487 || || 14A5 rRNA processing ; GO:0006364 | ISS with SWISS-PROT:O42832 nucleolus ; GO:0005730 | ISS with SWISSPROT:O4283 SCOP:53335 ' S-adenosyl-Lmethionine-dependent methyltransferases; CG8939|FBgn0030720|ppCT25670|FBan0008939 SCOP:55469 ' NADH oxidase/flavin reductase; CG8939|FBgn0030720|ppCT25670|FBan0008939 rRNA methyltransferase ; GO:0008649 ; EC:2.1.1.- | ISS with SWISSPROT:O42832::rRNA processing | nucleolus | rRNA methyltransferase || 14A514A5 || 1769197 || || 96B17 vesicle transport ; GO:0016192 | ISS with SWISS-PROT:P49755 Golgi stack ; GO:0005795 | ISS with SWISSPROT:P49755 IPR000348 ' emp24/gp25L/p24 family::vesicle-mediated transport | Golgi stack || 96B17 || 1775043 || || 20A1--2 glucose 6phosphate:phosphate antiporter ; GO:0008524 ; TC:2.A.1.4.5 | ISS with EMBL:AF020813::glucose 6- Mean log2 ISWI / wild type -3,3 -2,44 -2,4 -2,24 CT4004.A CT20766.A CT5200.A CT34379.A CT27300.A phosphate:phosphate antiporter || 20B120B1 || 1774413 || || 100B8 IPR000822 ' Zinc finger, C2H2 type SCOP:57667 ' C2H2 and C2HC zinc fingers; CG12054|FBgn0039831|ppCT4004|FBan0012054 || 100B8 || 1763384 || || 66D5 || 66D5 || 1781773 || Ecdysone receptor || DNA binding | neuronal remodeling | nucleus | ecdysteroid hormone receptor | ligand-dependent nuclear receptor | RNA polymerase I transcription factor::Ecdysone receptor 42A4--8 neuronal remodeling ; GO:0016322 | inferred from mutant phenotype nucleus ; GO:0005634 | inferred from direct assay nucleus ; GO:0005634 | NAS IPR000324 ' Vitamin D receptor IPR000536 ' Ligandbinding domain of nuclear hormone receptor IPR001628 ' C4-type steroid receptor zinc finger IPR001723 ' Steroid hormone receptor IPR003069 ' Ecdysteroid receptor (1H nuclear receptor) SCOP:48508 ' Nuclear receptor ligand-binding domain || 42A4--8 || 1760509 || EG:114D9.2, anon-EST:Posey148 || 1F1 IPR003104 ' Formin Homology 2 Domain actin binding ; GO:0003779 | ISS::actin binding || 1F1-1F2 || 1776935 || CG9659, CG9659, CG9659, zw4, l(1)zw4, zw-4, ZW-4, zeste-white 4, EG:BACR25B3.8, || egghead 3A6 integral plasma membrane protein ; GO:0005887 | -2,23 -2,22 -2,09 -2,08 -2,08 CT42452.A CT7722.A CT14049.A NAS SCOP:53448 ' Nucleotide-diphosphosugar transferases; egh|FBgn0001404|ppCT27300|FBan0009659::integral plasma membrane protein || 3A6 || 1779518 || foraging || foraging 24A2--4 larval feeding behavior (sensu Insecta) ; GO:0008342 | inferred from mutant phenotype larval locomotory behavior ; GO:0008345 | inferred from mutant phenotype IPR000719 ' Eukaryotic protein kinase IPR000961 ' Protein kinase C-terminal domain IPR001245 ' Tyrosine kinase catalytic domain IPR002290 ' Serine/Threonine protein kinase family active site IPR002373 ' cAMP-dependent protein kinase IPR002374 ' cGMP-dependent protein kinase SCOP:51206 ' cAMP-binding dom::protein serine/threonine kinase | cGMP-dependent protein kinase | feeding behavior | larval feeding behavior (sensu Insecta) | larval locomotory behavior || 24A2--4 || 1758619 || || 46D1 IPR000720 ' Peptidyl-glycine &agr;-amidating monooxygenase SCOP:50952 ' Soluble quinoprotein glucose dehydrogenase; CG12130|FBgn0033466|ppCT7722|FBan0012130 peptidyl-glycine monooxygenase ; GO:0004504 ; EC:1.14.17.3 | ISS with MGD:Pam; MGI:MGI:97475::peptidyl-glycine monooxygenase || 46C7 || 1783027 || anon-EST:fe1A11, anon-fast-evolving- -2 -1,91 -1,9 CT14053.A CT13748.A CT37817.A 1A11 || 66A9 || 66A8 || 1778556 || EG:22E5.8 || 2C8 protein amino acid phosphorylation ; GO:0006468 | ISS protein amino acid phosphorylation ; GO:0006468 | NAS IPR000719 ' Eukaryotic protein kinase IPR001245 ' Tyrosine kinase catalytic domain IPR002290 ' Serine/Threonine protein kinase family active site SCOP:56112 ' Protein kinase-like (PK-like); EG:22E5.8|FBgn0025625|ppCT14053|FBan0004290 protein serine/threonine kinase ; GO:0004674 ; EC:2.7.1.37 | inferred from sequ::protein amino acid phosphorylation | protein serine/threonine kinase || 2C8 || 1775419 || || 92F2 SCOP:55120 ' Pseudouridine synthase I; CG4159|FBgn0038811|ppCT13748|FBan0004159 pseudouridylate synthase ; GO:0004730 ; EC:4.2.1.70 | ISS with EMBL:AF116237; protein_id:AAD21041::pseudouridylate synthase || 92F2-92F2 || 1779191 || klarsicht || dynein ATPase | microtubule associated protein | microtubule-based movement::klarsicht 61C1--3 microtubulebased movement ; GO:0007018 | ISS microtubule associated protein ; GO:0005875 | ISS SCOP:46966 ' Spectrin repeat; kls|FBgn0001316|ppCT37817|FBan0017046 dynein ATPase ; GO:0008567 ; EC:3.6.4.2 | ISS || 61C161C3 || 1774081 -1,87 -1,86 -1,84 CT32983.A CT31192.A CT29146.A || CG13598, CG13598, CG13598, F125, TF125, TF125 type II, Dm Sba, AAF56201, Tf125, || 95C7--9 IPR001739 ' Methyl-CpG binding domain SCOP:54171 ' DNA-binding domain; sba|FBgn0016754|ppCT32983|FBan0013598 || 95C9--12 || 1770975 || || 96B6--8 IPR000050 ' Phosphotyrosine interaction (PID or PI) SCOP:48403 ' Ankyrin repeat; CG11168|FBgn0039249|ppCT31192|FBan0011168 SCOP:50729 ' PH domain-like; CG11168|FBgn0039249|ppCT31192|FBan0011168 || 96B6--8 || 1784442 || CG10377, CG10377, hrp48, rrm7, l(2)10280, l(2)2647, l(2)02647, 10280, RRM7, hnRN || Heterogeneous nuclear ribonucleoprotein at 27C 27C4 mRNA processing ; GO:0006397 | ISS with SGD:HRP1; SGDID:L0003022 nucleoplasm ; GO:0005654 | inferred from direct assay IPR000504 ' RNA-binding region RNP-1 (RNA recognition motif) SCOP:54928 ' RNA-binding domain, RBD; Hrb27C|FBgn0004838|ppCT29098|FBan0010377 SCOP:54928 ' RNA-binding domain, RBD; Hrb27C|FBgn0004838|ppCT29146|FBan0010377 RNA binding ; GO:0003723 | ISS::RNA binding | ribonucleoprotein complex | mRNA binding | mRNA processing | nucleoplasm || 27C4 || -1,81 -1,77 -1,73 CT40521.A CT21390.A CT2831.A 1761651 || Sex lethal || Sex lethal 6F3--5 dosage compensation ; GO:0007549 | NAS mRNA splicing ; GO:0006371 | NAS sex determination, primary response to X:A ratio ; GO:0007541 | NAS IPR000504 ' RNAbinding region RNP-1 (RNA recognition motif) IPR002343 ' Paraneoplastic encephalomyelitis antigen SCOP:54928 ' RNA-binding domain, RBD; Sxl|FBgn0003659|ppCT40521|FBan0018350 SCOP:54928 ' RNA-binding domain, RBD; Sxl|FBgn000365 || 6F3--5 || 1775355 || methuselah || 61C1 G-protein coupled receptor protein signaling pathway ; GO:0007186 | ISS integral membrane protein ; GO:0016021 | ISS IPR000832 ' Gprotein coupled receptors family 2 (secretinlike) SCOP:56869 ' Membrane all-alpha; mth|FBgn0023000|ppCT21390|FBan0006936 G-protein coupled receptor ; GO:0004930 | ISS G-protein coupled receptor ; GO:0004930 | NAS::Gprotein coupled receptor | integral membrane protein | stress response | aging | determination of adult life span || 61C1 || 1781875 || PP2Cb || 99B4 protein amino acid dephosphorylation ; GO:0006470 | NAS IPR000222 ' Protein phosphatase 2C subfamily IPR003588 ' Sigma factor PP2C- -1,73 -1,61 -1,6 CT34842.A CT20231.A CT34369.A CT17938.A like phosphatase IPR003589 ' Serine/threonine phosphatases 2C catalytic domain SCOP:56295 ' Protein serine/threonine phosphatase 2C; CG1906|FBgn0039672|ppCT2831|FBan0001906 protein serine/threonine phosphatase ; GO:0004722 ; EC:3.1.3.16 | NAS protein serine/threonine phosphatase ; GO:0004722::protein serine/threonine phosphatase | protein amino acid dephosphorylation || 99B4--5 || 1766481 || || 64A6 SCOP:47031 ' Second domain of FERM; CG14991|FBgn0035498|ppCT34842|FBan0014991 SCOP:47031 ' Second domain of FERM; CG14991|FBgn0035498|ppCT42895|FBan0014991 SCOP:50729 ' PH domain-like; CG14991|FBgn0035498|ppCT34842|FBan0014991 SCOP:50729 ' PH domain-like; CG14991|FBgn0035498|ppCT42895|FBan0014991 || 64A6 || 1760247 || Beadex || Beadex 17C4 SCOP:57716 ' Glucocorticoid receptor-like (DNA-binding domain); Bx|FBgn0000242|ppCT20231|FBan0006500 || 17C4 || 1762976 || || 20A3 || 20A3 || 1773696 || CAF1 || 68F1 nucleus ; GO:0005634 | ISS with SWISS-PROT:Q60809 non-specific RNA polymerase II transcription factor ; GO:0016252 | ISS with SWISSPROT:Q60809::general RNA polymerase II -1,6 -1,58 -1,57 -1,56 CT17696.A CT28151.A CT21869.A transcription factor || 68F1 || 1761734 || CG5605, CG5605, CG5605, l(3)neo28, l(3)05637, l(3)00103, l(3)77ABb, Dm0184, euka || 77B4--5 protein synthesis termination ; GO:0006415 | ISS protein synthesis termination ; GO:0006415 | NAS cytosol ; GO:0005829 | ISS translation release factor ; GO:0018444 | NAS IPR002555 ' eRF1-like proteins SCOP:53137 ' Translational machinery components; eRF1|FBgn0036974|ppCT17696|FBan0005605 SCOP:53137 ' Translational machinery components; eRF1|FBgn0036974|pp-CT::protein synthesis termination | cytosol | translation termination factor | translation release factor | translation release factor complex | cytoplasm | nascent polypeptide association || 77B4--5 || 1783203 || || 98E1 || 98D6 || 1776112 || fusilli || 52C3--4 EGF receptor signaling pathway ; GO:0007173 | IGI with FLYBASE:Egfr; FB:FBgn0003731 EGF receptor signaling pathway ; GO:0007173 | IGI with FLYBASE:cact; FB:FBgn0000250 IPR000504 ' RNA-binding region RNP-1 (RNA recognition motif) SCOP:54928 ' RNA-binding domain, RBD; fus|FBgn0023441|ppCT21869|FBan0008205 RNA binding ; GO:0003723 | ISS RNA binding ; GO:0003723 | non-traceable author s::RNA -1,55 -1,55 -1,52 CT31877.A CT30701.A CT1515.A CT34376.A binding | EGF receptor signaling pathway || 52B3-52B5 || 1790218 || || 54D1 anaphase-promoting complex ; GO:0005680 | ISS with EMBL:AF132794; protein_id:AAD30527.1 SCOP:49785 ' Galactose-binding domain-like; CG11419|FBgn0034231|ppCT31877|FBan0011419::anaphasepromoting complex || 54D1 || 1764551 || || 69E5 IPR003662 ' General substrate transporters IPR003663 ' Sugar transporters glucose transporter ; GO:0005355 | ISS with MGD:Slc2a2; MGI:MGI:1095438::glucose transporter || 69E5--6 || 1768656 || CG1099, CG1099, CG1099, p160, DAP160, DAP160, Dap160/intersectin, dap160, Dynam || 39A4--5 neurotransmitter release ; GO:0007269 | NAS synaptic vesicle endocytosis ; GO:0008099 | TAS IPR002048 ' EF-hand family SCOP:47473 ' EF-hand; Dap160|FBgn0023388|ppCT1515|FBan0001099 SCOP:50044 ' SH3domain; Dap160|FBgn0023388|ppCT1515|FBan0001099::synaptic vesicle endocytosis | neurotransmitter release || 39A4 || 1769174 || || 20A3 deubiquitylation ; GO:0006514 | ISS deubiquitylation ; GO:0006514 | TAS IPR001394 ' Ubiquitin carboxyl-terminal hydrolase family 2 ubiquitin-specific protease ; GO:0004843 | TAS ubiquitin- -1,52 -1,45 -1,43 -1,42 CT30047.A CT36459.A CT10576.A specific protease ; GO:0004843 | ISS::deubiquitination | ubiquitin-specific protease || 20A3 || 1769417 || brain tumor || brain tumor 37C5--6 IPR000315 ' B-box zinc finger superfamily SCOP:50960 ' TolB, C-terminal domain; brat|FBgn0010300|ppCT30047|FBan0010719::rRNA metabolism | oogenesis || 37C5--6 || 1771135 || Na pump alpha subunit || Na pump &agr; subunit 93B1--2 plasma membrane ; GO:0005886 | ISS with PIR:I49143 sodium/potassium-exchanging ATPase ; GO:0005890 | ISS with PIR:I49143 IPR000402 ' Na+,K+ ATPase &bgr; subunit IPR000661 ' H+/K+ and Na+/K+ transporting ATPase IPR001454 ' Haloacid dehalogenase/epoxide hydrolase family IPR001757 ' E1-E2 ATPases sodium/potassium-exchanging ATPase ; GO:0005391 ; EC:3.6.3.9 ; TC:3.A.3.1.1 ; TC:3.A.3.1.2 | infer::sodium/potassiumexchanging ATPase complex | hydrolase, acting on acid anhydrides, catalyzing transmembrane movement of substances || 93A4--B2 || 1783753 || anterior open (aop), yan || anterior open 22D1 induction of apoptosis ; GO:0006917 | inferred from mutant phenotype nucleus ; GO:0005634 | ISS with MGD:Ets1; MGI:MGI:95455 IPR000418 ' Ets-domain IPR002341 ' HSF/ETS DNA-binding domain -1,4 -1,4 -1,39 CT4830.A CT39978.A IPR003118 ' Sterile &agr; motif (SAM)/Pointed domain SCOP:47769 ' SAM/Pointed domain; aop|FBgn0000097|ppCT10576|FBan0003166 specific RNA polymerase II transcription factor ; GO:0003704 | ISS with MGD:Ets1; MGI:MGI:95::specific RNA polymerase II transcription factor | nucleus | induction of apoptosis | negative regulation of photoreceptor development || 22D1 || 1775810 || BcDNA:LD14168 || 98F5 mRNA cleavage ; GO:0006379 | ISS with SWISSPROT:Q10568 mRNA cleavage ; GO:0006379 | ISS with protein_id:Q10568 mRNA polyadenylation ; GO:0006378 | ISS with protein_id:Q10568 mRNA cleavage and polyadenylation specificity factor complex ; GO:0005847 | ISS with SWISSPROT:Q10568 mRNA cleavage and polyadenylation specificity factor complex ; GO:0005847 | inferred::mRNA cleavage | mRNA polyadenylation | mRNA binding, 3' UTR | mRNA cleavage and polyadenylation specificity factor complex || 98F5 || 1764107 || commissureless || Golgi apparatus | plasma membrane | axon guidance | axon midline choice point recognition::commissureless 71F2 axon guidance ; GO:0007411 | NAS axon midline choice point recognition ; GO:0016199 | -1,37 -1,37 CT23101.A CT7240.A CT26944.A CT42531.A TAS Golgi apparatus ; GO:0005794 | inferred from direct assay plasma membrane ; GO:0005886 | inferred from direct assay || 71F2 || 1788794 || AC017581 || 78D6 protein amino acid phosphorylation ; GO:0006468 | ISS IPR000719 ' Eukaryotic protein kinase IPR002290 ' Serine/Threonine protein kinase family active site SCOP:56112 ' Protein kinase-like (PK-like); CG7597|FBgn0037093|ppCT23101|FBan0007597 cyclin-dependent protein kinase ; GO:0004693 ; EC:2.7.1.- | ISS [RNA-polymerase]-subunit kinase ; GO:0008353 ; EC:2.7.1.141 | ISS with SGD:CTK1; SGD::cyclin-dependent protein kinase | [RNA-polymerase]-subunit kinase | protein amino acid phosphorylation || 78D578D5 || 1766012 || elongation initiation factor 5C || 83B4 protein synthesis initiation ; GO:0006413 | NAS cytosol ; GO:0005829 | NAS IPR003307 ' eIF4-&ggr;/eIF5/eIF2-&egr; translation initiation factor ; GO:0003743 | NAS::translation initiation factor | cytosol | protein synthesis initiation || 83B4 || 1763880 || || 26D1 SCOP:48452 ' Tetratricopeptide repeat (TPR); CG9523|FBgn0031812|ppCT26944|FBan0009523 || 26D1 || 1761182 || || 94A10 SCOP:48371 ' ARM repeat; CG18596|FBgn0038953|pp- -1,33 -1,31 -1,3 -1,29 CT30735.A CT33081.A CT9059.A CT42531|FBan0018596 || 94A10 || 1788365 || small optic lobes || calpain | optokinetic behavior::small optic lobes 19F5 optokinetic behavior ; GO:0007634 | NAS IPR000169 ' Eukaryotic thiol (cysteine) proteases active site IPR001300 ' Calpain-type cysteinprotease (C2 family) calpain ; GO:0004198 ; EC:3.4.22.17 | ISS with EMBL:AF015038 || 19F5 || 1762090 || || 96C8 || 96C8 || 1774397 || lethal (2) giant larvae || lethal (2) giant larvae 21A2 TGFbeta receptor signaling pathway ; GO:0007179 | IGI with FLYBASE:dpp; FB:FBgn0000490 polarity of follicular epithelium ; GO:0016334 | IGI with FLYBASE:dlg1; FB:FBgn0001624 apicolateral plasma membrane ; GO:0016327 | inferred from direct assay extracellular matrix ; GO:0005578 | inferred from direct assay plasma membrane ; GO:0005886 | inferred from direct assay SCOP:50978 ' Trp-Asp repeat (WD::myosin II binding | septate junction | neurotransmitter release | synaptic vesicle priming | TGFbeta receptor signaling pathway | establishment and/or maintenance of epithelial cell polarity | establishment and/or maintenance of neuroblast cell polarity | basal protein localization | cell differentiation | establishment and/or maintenance of polarity of larval imaginal disc epithelium | -1,26 -1,26 -1,26 CT14206.A CT34766.A CT20209.A establishment and/or maintenance of polarity of embryonic epithelium || 21A2 || 1789039 || || 92E2--3 IPR000822 ' Zinc finger, C2H2 type SCOP:57667 ' C2H2 and C2HC zinc fingers; CG4360|FBgn0038787|ppCT14206|FBan0004360 || 92E2--3 || 1789581 || crooked legs || 33A1--2 IPR000822 ' Zinc finger, C2H2 type SCOP:57667 ' C2H2 and C2HC zinc fingers; crol|FBgn0020309|ppCT34766|FBan0014938 RNA polymerase II transcription factor ; GO:0003702 | ISS with EMBL:AF082568; protein_id:AAD38426.1::RNA polymerase II transcription factor || 33A1-33A2 || 1786282 || CG6562, CG6562, CG6562, IPP, Synj || 58D1 synaptic vesicle endocytosis ; GO:0008099 | TAS IPR000300 ' Inositol polyphosphate related phosphatase family SCOP:56219 ' DNase I-like; synaptojanin|FBgn0034691|ppCT20209|FBan0006562 SCOP:56219 ' DNase I-like; synaptojanin|FBgn0034691|ppCT43303|FBan0006562 inositol-1,4,5trisphosphate phosphatase ; GO:0016313 | NAS inositol-1,4,5-trisphosphate 5phosphatase ; GO:0004445 ; EC:3.1.3.56 | inferred from direct assay::inositol-1,4,5trisphosphate phosphatase | synaptic vesicle endocytosis | dephosphorylation | -1,25 -1,24 -1,23 CT31127.A CT34070.A CT32121.A CT8052.A CT10621.A neurotransmitter release | inositol-1,4,5trisphosphate 5-phosphatase || 58B4 || 1767277 || || 80D2 IPR000953 ' Chromo domain SCOP:54160 ' Chromo domain-like; CG10712|FBgn0037201|ppCT31127|FBan0010712 SCOP:54160 ' Chromo domain-like; CG10712|FBgn0037201|ppCT31129|FBan0010712 || 80B2-80B2 || 1784331 || cg14414, BcDNA:AT01764 || 12F1 IPR000504 ' RNA-binding region RNP-1 (RNA recognition motif) SCOP:54928 ' RNA-binding domain, RBD; CG14414|FBgn0030571|ppCT34070|FBan0014414 RNA binding ; GO:0003723 | ISS::RNA binding || 12F1 || 1773005 || || 85C5 IPR000822 ' Zinc finger, C2H2 type potassium channel regulator ; GO:0015459 | ISS with EMBL:AF143859; protein_id:AAD31040.1::potassium channel regulator || 85C2-85C2 || 1773281 || || 45B1 || 45A12 || 1767685 || Trehalose receptor 1 || G-protein coupled receptor, unknown ligand | taste receptor | integral membrane protein | taste | sweet taste perception | G-protein coupled receptor protein signaling pathway::Trehalose receptor 1 5A11--12 Gprotein coupled receptor protein signaling -1,22 -1,22 -1,22 -1,22 -1,22 CT34389.A CT40312.A pathway ; GO:0007186 | ISS taste ; GO:0007607 | inferred from mutant phenotype integral membrane protein ; GO:0016021 | ISS IPR000276 ' Rhodopsinlike GPCR superfamily G-protein coupled receptor, unknown ligand ; GO:0016526 | ISS taste receptor ; GO:0008527 | NAS || 5A11-5A12 || 1773429 || || 1E1 || 1E1 || 1786188 || CG3725, l(2)k08308ab, l(2)k09025, Ca<up>2+</up>ATPase, CA-P60A, SERCA, sarco/end || Calcium ATPase at 60A 60B5 endoplasmic reticulum ; GO:0005783 | ISS IPR001454 ' Haloacid dehalogenase/epoxide hydrolase family IPR001757 ' E1-E2 ATPases SCOP:56869 ' Membrane all-alpha; CaP60A|FBgn0004551|ppCT12479|FBan0003725 SCOP:56869 ' Membrane all-alpha; CaP60A|FBgn0004551|ppCT40312|FBan0003725 SCOP:56869 ' Membrane all-alpha; CaP60A|FBgn0004551|ppCT40314|FBan0003725 SCOP:56869 ' Membrane all-alpha; CaP60A|FBgn0004551|ppCT40316|FBan00::hydrolase, acting on acid anhydrides, catalyzing transmembrane movement of substances | calciumtransporting ATPase | endoplasmic reticulum | endoplasmic reticulum -1,21 -1,21 CT38779.A CT1866.A membrane | sarcoplasmic reticulum | integral membrane protein | calcium ion transport || 60A11--12 || 1779258 || doughnut on 2 || doughnut on 2 37D2 protein amino acid phosphorylation ; GO:0006468 | ISS signal transduction ; GO:0007165 | ISS plasma membrane ; GO:0005886 | ISS IPR000719 ' Eukaryotic protein kinase IPR001245 ' Tyrosine kinase catalytic domain IPR003306 ' WIF domain SCOP:56112 ' Protein kinase-like (PK-like); dnt|FBgn0024245|ppCT38779|FBan0017559 protein tyrosine kinase ; GO:0004713 ; EC:2.7.1.112 | non::protein tyrosine kinase | transmembrane receptor protein tyrosine kinase | plasma membrane | signal transduction | protein amino acid phosphorylation || 37D2 || 1790550 || || 64C2 mitochondrion ; GO:0005739 | ISS with SGD:NAM2; SGDID:L0001229 IPR001412 ' Aminoacyl-transfer RNA synthetases class-I IPR002300 ' t-RNA synthetase, class Ia IPR002302 ' LeucyltRNA synthetase SCOP:47323 ' Anticodonbinding domain of a subclass of class I aminoacyl-tRNA synthetases; CG7479|FBgn0035576|ppCT1866|FBan0007479 SCOP:50677 ' ValRS/IleRS editing domain; CG7479|FBgn0035576|ppCT1866|FBan0007479 SCOP:52374 ' -1,18 -1,18 CT9874.A CT39486.A CT17830.A CT22273.A Nucleotidylyl transferase; CG7479|FBgn0035576|ppCT1866|F::leucine-tRNA ligase | mitochondrion || 64C2 || 1785811 || || 60E12 SCOP:47923 ' Ypt/Rab-GAP domain of gyp1p; CG16896|FBgn0035073|ppCT9874|FBan0016896 SCOP:50978 ' TrpAsp repeat (WD-repeat); CG16896|FBgn0035073|ppCT9874|FBan0016896 || 60E12 || 1769275 || || 84E3 || 84E3 || 1766157 || CG5643, CG5643, CG5643, CG5643, CG5643, CG5643, 0318/07, LD02456, EP3559, l(3)S0 || 98A10 protein phosphatase type 2A ; GO:0000159 | ISS with EMBL:U37769 IPR002554 ' Protein phosphatase 2A regulatory B subunit (B56 family) protein serine/threonine phosphatase ; GO:0004722 ; EC:3.1.3.16 | ISS with EMBL:U37769::protein serine/threonine phosphatase | protein phosphatase type 2A complex || 98A6-98A8 || 1759497 || heartless || gonadal mesoderm development | larval visceral muscle development | heart development | mesoderm development | receptor signaling protein tyrosine kinase | somatic muscle development | fibroblast growth factor receptor | germ-cell migration | endoderm development | central nervous -1,18 -1,17 -1,16 -1,15 CT13760.A CT3411.A system development | glia cell migration::heartless 90E1 fate specification in mesoderm ; GO:0007501 | IGI with FLYBASE:dpp; FB:FBgn0000490 plasma membrane ; GO:0005886 | ISS IPR000719 ' Eukaryotic protein kinase IPR001245 ' Tyrosine kinase catalytic domain IPR003006 ' Immunoglobulin and major histocompatibility complex domain IPR003598 ' Immunoglobulin C-2 type IPR003600 ' Immunoglobulin-like SCOP:48726 ' Immunoglobulin; htl|FBgn0010389|pp-CT22273|FBan000722 || 90E1 || 1775734 || ubiquinol-cytochrome c reductase, anonEST:Posey245 || 73A9 ubiquinolcytochrome c reductase ; GO:0015008 | NAS IPR001431 ' Insulinase family (Peptidase family M16) SCOP:55994 ' Mitochondrial processing peptidase, MPP; CG4169|FBgn0036642|ppCT13760|FBan0004169 ubiquinolcytochrome c reductase ; GO:0008121 ; EC:1.10.2.2 ; TC:3.D.3.-.- | NAS::ubiquinolcytochrome c reductase (sensu Eukarya) | ubiquinol-cytochrome c reductase || 73A9 || 1766991 || CG1453, CG1453, DmKlp10A, DmCG1453, KIF2A, KLP10A || 10A6 microtubule-based movement ; GO:0007018 | ISS with MGD:Kif2; MGI:MGI:108390 kinesin ; GO:0005871 | -1,15 -1,14 CT21414.A CT2946.A ISS with MGD:Kif2; MGI:MGI:108390 kinesin ; GO:0005871 | ISS with SWISSPROT:O00139 IPR001752 ' Kinesin motor domain SCOP:52540 ' P-loop containing nucleotide triphosphate hydrolases; Klp10A|FBgn0030268|ppCT3411|FBan0001453 motor ; GO:0003774 | ISS with SWISS-::kinesin motor | motor | kinesin | microtubule-based movement || 10A6 || 1775171 || CG6963, CG6963, CG6963, CG6963, CG6963, ms(3)89B, Hrr25, CKIg-like, CKI&ggr;, CK || 89B16--17 glia cell migration ; GO:0008347 | inferred from mutant phenotype spermatogenesis ; GO:0007283 | inferred from mutant phenotype IPR000719 ' Eukaryotic protein kinase IPR002290 ' Serine/Threonine protein kinase family active site SCOP:56112 ' Protein kinase-like (PK-like); gish|FBgn0011253|ppCT21414|FBan0006963 SCOP:56112 ' Protein kinase-like (PK-like); gish|FBgn0011253|ppCT39940|FBan0006963 casein kinase I ; GO:0004681 ; EC:2.7.1.- | inferred from sequence similarit::casein kinase I | glia cell migration | protein amino acid phosphorylation | spermatogenesis || 89B9-12 || 1788712 || || 64A10 SCOP:50978 ' Trp-Asp repeat (WD-repeat); CG1332|FBgn0035514|pp- -1,14 -1,13 CT20536.A CT36405.A CT20848.A CT2946|FBan0001332 sphingomyelin phosphodiesterase activator ; GO:0016230 | ISS with SWISSPROT:O35242::sphingomyelin phosphodiesterase activator || 64A1064A10 || 1773276 || || 17C6--7 SCOP:49562 ' C2 domain (Calcium/lipid-binding domain, CaLB); CG6606|FBgn0030942|ppCT20536|FBan0006606 || 17C6--7 || 1770909 || CG11525, CG11525, CG11525, clone 1.25, clone 2.24, dCycG, CG 11525, cyclin G1, i || 100E2--3 DNA repair ; GO:0006281 | NAS cyclin-dependent protein kinase, regulator ; GO:0016538 | ISS with EMBL:U95826 cyclin-dependent protein kinase, regulator ; GO:0016538 | NAS::cyclin-dependent protein kinase, regulator | DNA repair || 100C7 || 1786676 || CG6715, CG6715, KP78A, Kp78A || 86E4 protein amino acid phosphorylation ; GO:0006468 | ISS protein amino acid phosphorylation ; GO:0006468 | NAS IPR000719 ' Eukaryotic protein kinase IPR001245 ' Tyrosine kinase catalytic domain IPR002290 ' Serine/Threonine protein kinase family active site SCOP:56112 ' Protein kinase-like (PK-like); KP78a|FBgn0026064|ppCT20848|FBan0006715 protein kinase ; GO:0004672 | ISS protein serine/thr::protein -1,13 -1,1 -1,08 CT16954.A CT28173.A CT21682.A kinase | protein serine/threonine kinase | protein amino acid phosphorylation || 86E4 || 1763331 || CG5336, Dced-12 || 33C4 SCOP:50729 ' PH domain-like; CG5336|FBgn0032409|ppCT16954|FBan0005336 site-specific DNAmethyltransferase (cytosine-specific) ; GO:0008326 ; EC:2.1.1.73 | ISS with EMBL:AF012129::site-specific DNAmethyltransferase (cytosine-specific) || 33C4-33C4 || 1787802 || || 96B20 IPR002495 ' Glycosyl transferase family 8 SCOP:53448 ' Nucleotide-diphospho-sugar transferases; CG9996|FBgn0039273|ppCT28173|FBan0009996 || 96B20 || 1790426 || || 4C13 pyruvate dehydrogenase (lipoamide) ; GO:0009364 | ISS with MGD:Pdha1; MGI:MGI:97532 IPR001017 ' Dehydrogenase, E1 component SCOP:52518 ' Thiamin diphosphate-binding fold (THDP-binding); CG7010|FBgn0029721|ppCT21682|FBan0007010 SCOP:52518 ' Thiamin diphosphate-binding fold (THDPbinding); CG7010|FBgn0029721|ppCT36325|FBan0007010 SCOP:52518 ' Thiamin diphosphate-binding fold (THDPbinding); CG7010|FBgn0029721|ppCT36327|FBan0007010 pyruvate deh::pyruvate dehydrogenase (lipoamide) | pyruvate dehydrogenase complex -1,05 -1,05 -1,05 CT19788.A CT17940.A (lipoamide) || 4C13 || 1762919 || || 17C1 IPR000738 ' WHEP-TRS domain IPR002106 ' Aminoacyl-transfer RNA synthetases class-II IPR002314 ' tRNA synthetases, class-II (G, H, P and S) SCOP:47060 ' S15/NS1 RNA-binding domain; CG6335|FBgn0030934|ppCT19788|FBan0006335 SCOP:52954 ' Anticodon-binding domain of Class II aaRS; CG6335|FBgn0030934|ppCT19788|FBan0006335 SCOP:55681 ' Class II aaRS and biotin synthetases; CG6335|FBgn0030934|ppCT19788|FBan0006335 histidine-tRNA ligase ; GO:0004821 ; EC:6.1.1.21 | inferred fro::histidine-tRNA ligase || 17C1-17C1 || 1777430 || CG5686, flipper, fs(2)4, IRS, BcDNA.GH11263, dIRS, CHICO, BcDNA:GH11263, chic, f || chico 31B1 insulin receptor signaling pathway ; GO:0008286 | IGI with FLYBASE:InR; FB:FBgn0013984 insulin receptor signaling pathway ; GO:0008286 | IGI with FLYBASE:Pi3k92E; FB:FBgn0015279 insulin-like growth factor receptor binding protein complex ; GO:0016942 | ISS with MGD:Irs1; MGI:MGI:99454 IPR002404 ' Insulin receptor substrate-1 PTB domain SCOP:50729 ' PH domain-like; chico|FBgn0024248::insulin-like growth factor receptor binding | insulin-like growth -1,05 -1,05 CT1595.A CT34373.A CT12433.A CT35708.A CT9291.A CT9121.A CT14005.A factor receptor binding protein complex | insulin receptor signaling pathway | positive regulation of cell growth | cell shape and cell size control | aging | egg chamber growth | vitellogenesis || 31B1 || 1772659 || || 63D2 endoplasmic reticulum ; GO:0005783 | ISS with SWISSPROT:P55072 IPR003593 ' AAA ATPase superfamily SCOP:49503 ' Cupredoxins; CG12010|FBgn0035443|ppCT1595|FBan0012010 SCOP:52540 ' Ploop containing nucleotide triphosphate hydrolases; CG12010|FBgn0035443|ppCT1595|FBan0012010 adenosinetriphosphatase ; GO:0004002 ; EC:3.6.1.3 | ISS with SWISSPROT:P55072::endoplasmic reticulum | adenosinetriphosphatase || 63D2 || 1772950 || || 20A3--4 SCOP:53254 ' Phosphoglycerate mutase-like; CG14616|FBgn0031192|ppCT34373|FBan0014616 SCOP:56059 ' Glutathione synthetase ATP-binding domain-like; CG14616|FBgn0031192|ppCT34373|FBan0014616 || 20A3--4 || 1770044 || || 21B1 || 21B1 || 1769285 || || 83E1 || 83E1 || 1764104 || EG:66A1.2 || 4C10 || 4C10 || 1763646 || EG:95B7.10, EG:100G10.8 || 3B3 || 3B3 || 1766273 || moira || general RNA polymerase II -1,04 -1,03 -1,03 -1,02 -1 -1 -0,99 CT13314.A CT40222.A transcription factor | nucleosome remodeling complex | chromatin modeling::moira 89A11 chromatin modeling ; GO:0006338 | NAS nucleosome remodeling complex ; GO:0005679 | ISS with EMBL:U85614 IPR001005 ' Myb DNA binding domain SCOP:46689 ' Homeodomain-like; mor|FBgn0002783|ppCT14005|FBan0018740 non-specific RNA polymerase II transcription factor ; GO:0016252 | ISS with EMBL:U85614 || 89A11 || 1759544 || genghis khan || 60C2 actin polymerization and/or depolymerization ; GO:0008154 | inferred from mutant phenotype protein amino acid phosphorylation ; GO:0006468 | ISS IPR000719 ' Eukaryotic protein kinase IPR000961 ' Protein kinase C-terminal domain IPR001180 ' Citron homology domain IPR002219 ' Phorbol esters/diacylglycerol binding domain IPR002290 ' Serine/Threonine protein kinase family active site SCOP:56112 ' Protein kinase-like (PK-like); gek|FBgn0023081|pp-::protein kinase | protein serine/threonine kinase | diacylglycerol binding | actin polymerization and/or depolymerization | actin polymerization/depolymerization regulation | protein amino acid phosphorylation || 60C2 || 1788966 || BcDNA:GH06348, BcDNA, GH06348 || -0,99 -0,99 CT23818.A CT25044.A 46B13--C1 IPR000891 ' HMG-CoA Lyaselike family IPR000901 ' Carbamoylphosphate synthase IPR001882 ' Biotinrequiring enzymes attachment site. SCOP:51230 ' Single hybrid motif; BcDNA:GH06348|FBgn0027580|ppCT3885|FBan0001516 SCOP:51230 ' Single hybrid motif; BcDNA:GH06348|FBgn0027580|ppCT40220|FBan0001516 SCOP:51230 ' Single hybrid motif; BcDNA:GH06348|FBgn0027580|ppCT40222|FBan0001516 SCOP:51230 ' Single hybrid motif; BcDNA:GH06348|FBgn0027580|ppCT43142|FBan0001516 SCOP:5::pyruvate carboxylase || 46B9--12 || 1790119 || cg7878, DmRH26 || 84E13 IPR000629 ' ATP-dependent helicase, DEAD-box IPR000958 ' KH domain IPR001410 ' DEAD/DEAH box helicase IPR001650 ' Helicase C-terminal domain SCOP:52540 ' P-loop containing nucleotide triphosphate hydrolases; CG7878|FBgn0037549|ppCT23818|FBan0007878 SCOP:54791 ' KHdomain; CG7878|FBgn0037549|ppCT23818|FBan0007878 helicase ; GO:0004386 | ISS ATP dependent RNA helicase ; GO:0004004 ; EC:3.6.1.3 | ISS with SGD:DBP::helicase | ATP dependent RNA helicase || 84E13 || 1760901 || Fimbrin || 16A1 female meiosis -0,97 -0,97 CT21340.A CT25035.A CT33825.A CT19310.A CT9736.A chromosome segregation ; GO:0016321 | inferred from mutant phenotype IPR002048 ' EF-hand family SCOP:47473 ' EF-hand; Fim|FBgn0024238|ppCT25044|FBan0008649 SCOP:47576 ' Calponin-homology domain, CH-domain; Fim|FBgn0024238|ppCT25044|FBan0008649 actin binding ; GO:0003779 | ISS actin binding ; GO:0003779 | NAS::actin binding | female meiosis chromosome segregation || 16A116A1 || 1789676 || BcDNA:AT16346 || 71B8 IPR000866 ' AhpC/TSA family SCOP:52833 ' Thioredoxin-like; CG6888|FBgn0036490|ppCT21340|FBan0006888 thioredoxin peroxidase ; GO:0008379 ; EC:1.11.1.- | ISS with SWISS-PROT:P35704::thioredoxin peroxidase || 71B8-71B8 || 1790392 || || 49C3 SCOP:46955 ' Putative DNAbinding domain; CG8632|FBgn0033762|ppCT25035|FBan0008632 || 49B11 || 1766165 || || 18D8 SCOP:56784 ' HAD-like; CG14212|FBgn0031045|ppCT33825|FBan0014212 || 18D8 || 1784098 || || 72A1 || 72A1 || 1765415 || pole hole || pole hole 3A1 dorsal/ventral axis determination, follicular epithelium ; GO:0008069 | inferred from mutant phenotype signal transduction ; GO:0007165 | IGI signal transduction ; GO:0007165 | inferred from mutant -0,97 -0,96 -0,96 -0,95 -0,93 CT26561.A CT40310.A phenotype spermatogenesis ; GO:0007283 | inferred from mutant phenotype terminal region determination ; GO:0007362 | inferred from mutant phenotype cytoplasm ; GO:0005737 | TAS extrinsic plasma membrane protein ; GO:001989::signal transduction | spermatogenesis | protein serine/threonine kinase | dorsal/ventral axis determination, follicular epithelium | terminal region determination | extrinsic plasma membrane protein | oogenesis | diacylglycerol binding || 3A1 || 1787623 || || 87F10--11 SCOP:50729 ' PH domainlike; CG9351|FBgn0038169|ppCT26561|FBan0009351 || 87F10-87F11 || 1780788 || CG2835, G<down>s</down>&agr;, Gs&agr;, dgs&agr;, dgs, Gs, G&agr;s, G<down>S</dow || G protein s&agr; 60A 60B6--7 G-protein coupled receptor protein signaling pathway ; GO:0007186 | ISS with SWISS-PROT:O16118 heterotrimeric Gprotein complex ; GO:0005834 | ISS with SWISS-PROT:O16118 plasma membrane ; GO:0005886 | inferred from direct assay IPR000367 ' G-protein &agr; subunit group S IPR001019 ' Guanine nucleotide binding protein (G-protein), &agr; subunit heterotrimeric G-protein GTPase ; GO:0003927 ; EC:::larval/pupal development (sensu Insecta) | heterotrimeric G-protein GTPase, alpha- -0,93 -0,93 CT34391.A CT41659.A CT24433.A CT39088.A subunit | G-protein coupled receptor protein signaling pathway | response to cocaine (sensu Insecta) | visual behavior | learning and memory | adenylate cyclase activation | heterotrimeric G-protein complex | heterotrimeric G-protein GTPase || 60A12-13 || 1774954 || || 1D2 || 1D2 || 1788036 || Calmodulin || Calmodulin 48F8--10 metarhodopsin inactivation ; GO:0016060 | IGI with FLYBASE:G&agr;49B; FB:FBgn0004435 cytoplasm ; GO:0005737 | inferred from direct assay rhabdomere ; GO:0016028 | inferred from direct assay IPR002048 ' EF-hand family SCOP:47473 ' EF-hand; Cam|FBgn0000253|ppCT24787|FBan0008472 SCOP:47473 ' EFhand; Cam|FBgn0000253|ppCT41655|FBan0008472 SCOP:47473 ' EFhand; Cam|FBgn0000253|ppCT41657|FBan0008472 SCOP:47473 ' EFhand; Cam|FBgn00::calcium ion binding | rhabdomere | calcium ion sensing | metarhodopsin inactivation | regulation of light-activated channels | rhodopsin mediated signaling || 48F1-48F6 || 1789753 || || 85B3 SCOP:48452 ' Tetratricopeptide repeat (TPR); CG8223|FBgn0037624|ppCT24433|FBan0008223 || 85B3 || 1778083 || polyA-binding protein || poly(A) binding | RNA binding | cytoplasm::polyA-binding protein 55C1 cytoplasm ; GO:0005737 | -0,92 -0,91 -0,9 -0,9 CT42366.A inferred from direct assay IPR000504 ' RNA-binding region RNP-1 (RNA recognition motif) SCOP:54928 ' RNAbinding domain, RBD; pAbp|FBgn0003031|ppCT16411|FBan0005119 SCOP:54928 ' RNA-binding domain, RBD; pAbp|FBgn0003031|ppCT39086|FBan0005119 SCOP:54928 ' RNA-binding domain, RBD; pAbp|FBgn0003031|ppCT39088|FBan0005119 RNA binding ; GO:0003723 | ISS poly(A) binding ; GO:0008143 | inferred from se || 55B8-55B9 || 1774301 || CG16760, c62E-15 || 62E4 IPR001369 ' Purine and other phosphorylases family 2 IPR002625 ' Smr domain SCOP:53167 ' Purine and uridine phosphorylases; CG16758|FBgn0035348|ppCT42366|FBan0016758 SCOP:53167 ' Purine and uridine phosphorylases; CG16758|FBgn0035348|ppCT8044|FBan0016758 SCOP:53167 ' Purine and uridine phosphorylases; CG16758|FBgn0035348|ppCT8048|FBan0016758 SCOP:53167 ' Purine and uridine phosphorylases; CG16758|FBgn0035348|ppCT8050|FBan0016758 purine-nucleoside phosphorylase ; GO:00::62E4 IPR001369 ' Purine and other phosphorylases family 2 -0,89 CT10899.A CT4336.A IPR002625 ' Smr domain SCOP:53167 ' Purine and uridine phosphorylases; CG16758|FBgn0035348|ppCT42366|FBan0016758 SCOP:53167 ' Purine and uridine phosphorylases; CG16758|FBgn0035348|ppCT8044|FBan0016758 SCOP:53167 ' Purine and uridine phosphorylases; CG16758|FBgn0035348|ppCT8048|FBan0016758 SCOP:53167 ' Purine and uridine phosphorylases; CG16758|FBgn0035348|ppCT8050|FBan0016758 purine-nucleoside phosphorylase ; GO:0004731::purinenucleoside phosphorylase || 62E4 || 1789756 || sister of odd and bowl || nucleus | RNA polymerase II transcription factor::sister of odd and bowl 24A1 nucleus ; GO:0005634 | ISS with FLYBASE:odd; FB:FBgn0002985 IPR000822 ' Zinc finger, C2H2 type SCOP:57667 ' C2H2 and C2HC zinc fingers; sob|FBgn0004892|ppCT10899|FBan0003242 SCOP:57903 ' FYVE/PHD zinc finger; sob|FBgn0004892|ppCT10899|FBan0003242 RNA polymerase II transcription factor ; GO:0003702 | ISS with FLYBASE:odd; FB:FBgn0002985 || 24A1 || 1789520 || Thioredoxin reductase-1 || Thioredoxin reductase-1 7D22--E1 NOT oxidized -0,88 -0,85 CT32098.A CT23173.A CT2162.A CT33229.A glutathione reduction ; GO:0006128 | inferred from direct assay thioredoxin pathway ; GO:0006125 | inferred from direct assay IPR000815 ' Mercuric reductase IPR001100 ' Pyridine nucleotide-disulfide oxidoreductase, class I IPR001327 ' FADdependent pyridine nucleotide-disulfide oxidoreductase SCOP:51905 ' FAD/NAD(P)-binding domain; Trxr1|FBgn0020653|pp-CT42286|FBan0002151 SCOP:51905 ' FAD/NAD(P)-binding domain; Trxr-1|FBgn0020653|p::glutathione reductase (NADPH) | thioredoxin reductase (NADPH) | cytoplasm | oxidized glutathione reduction | thioredoxin pathway || 7D22--E1 || 1777255 || || 85E6 SCOP:48371 ' ARM repeat; CG16908|FBgn0037741|ppCT32098|FBan0016908 || 85E6 || 1769107 || CG7574, bip-I || 66B3 || 66B3 || 1764702 || || 63B7 || 63B7 || 1788897 || CG13755, CG12495, CG13754, CG2385, CG8278, CG13753, CG13752, CG33141, CG18464, C || 44F1--2 larval visceral muscle development ; GO:0007523 | inferred from mutant phenotype myoblast fusion ; GO:0007520 | inferred from mutant phenotype plasma membrane ; GO:0005886 | inferred from direct assay plasma membrane ; GO:0005886 | ISS with EMBL:AF035385 IPR003598 ' Immunoglobulin C-2 type IPR003600 ' -0,85 -0,85 -0,84 -0,84 CT30699.A CT27400.A CT27668.A CT42591.A Immunoglobulin-like SCOP:48726 ' Immunoglobulin; sns|FBgn0024189|ppCT33230|FBan0013753 SCOP:48726 ' Immunoglobulin; sns|FBgn0024189|ppCT3323::cell adhesion molecule | plasma membrane | myoblast fusion | larval visceral muscle development || 44F1 || 1773954 || || 7D14 || 7D14 || 1790938 || Disabled || Disabled 73C1 cytoplasm ; GO:0005737 | inferred from direct assay cytoplasm ; GO:0005737 | NAS IPR000050 ' Phosphotyrosine interaction (PID or PI) SCOP:50729 ' PH domain-like; Dab|FBgn0000414|ppCT27400|FBan0009695::cytoplasm | neurogenesis || 73C1 || 1789769 || Chromosome-associated protein || Chromosome-associated protein 14F1 sister chromatid cohesion ; GO:0007062 | ISS with SGD:SMC3; SGDID:L0003992 cohesin ; GO:0008278 | ISS with SGD:SMC3; SGDID:L0003992 IPR003395 ' SMC domain N terminal domain IPR003405 ' SMC family, C-terminal domain IPR003439 ' ABC transporter SCOP:52540 ' P-loop containing nucleotide triphosphate hydrolases; Cap|FBgn0015615|ppCT27543|FBan0009748 SCOP:52540 ' Ploop containing nucleot::cohesin | sister chromatid cohesion || 14F1 || 1784678 || CG7734, CG7734, CG7734, CG7734, quo: quo vadis, l(2)04738, EP2359, -0,83 -0,83 -0,83 -0,83 CT39920.A EP(2)2359, SD || TGFbeta receptor signaling pathway | wing morphogenesis | anterior/posterior pattern formation, imaginal disc | RNA polymerase II transcription factor | ectoderm development | repression of transcription, from Pol II promoter | wing vein morphogenesis | cell proliferation | midgut development::schnurri 47E1 wing morphogenesis ; GO:0007476 | IGI with FLYBASE:dpp; FB:FBgn0000490 nucleus ; GO:0005634 | NAS IPR000822 ' Zinc finger, C2H2 type IPR003604 ' U1-like zinc finger SCOP:57667 ' C2H2 and C2HC zinc fingers; shn|FBgn0003396|ppCT23537|FBan0007734 SCOP:57667 ' C2H2 and C2HC zinc fingers; shn|FBgn0003396|ppCT42591|FBan0007734 RNA polymerase II transcription factor ; GO:0003702 | NAS tr || 47D6--E1 || 1783809 || Myosin heavy chain || Myosin heavy chain 36B1 muscle myosin ; GO:0005859 | ISS with MGD:Myhca; MGI:MGI:97255 myosin ; GO:0016459 | ISS IPR001609 ' Myosin head (motor domain) SCOP:50084 ' Myosin S1 fragment, N-terminal domain; Mhc|FBgn0002741|ppCT39920|FBan0017927 SCOP:52540 ' Ploop containing nucleotide triphosphate hydrolases; Mhc|FBgn0002741|ppCT39920|FBan0017927 myosin ATPase ; GO:0008570 ; EC:3.6.4.1 | ISS::myosin -0,82 CT28779.A CT20642.A ATPase | muscle motor | structural constituent of muscle | myosin | muscle myosin | striated muscle thick filament | striated muscle contraction || 36B1 || 1785315 || CG10239, CG10244, CG10239, CG10244, CG10239, DmHD-14, HD-14, FGFR1-like, CT28779 || 96C4--5 calciumdependent cell-cell adhesion ; GO:0016339 | ISS protein amino acid phosphorylation ; GO:0006468 | ISS integral plasma membrane protein ; GO:0005887 | ISS IPR000719 ' Eukaryotic protein kinase IPR001245 ' Tyrosine kinase catalytic domain IPR002126 ' Cadherin domain SCOP:56112 ' Protein kinase-like (PK-like); HD-14|FBgn0022800|ppCT28777|FBan0010239 protein kinase ; GO:0004672::calcium-dependent cell-cell adhesion | protein tyrosine kinase | protein amino acid phosphorylation | calciumdependent cell adhesion molecule | protein kinase | integral plasma membrane protein | transmembrane receptor protein tyrosine kinase || 96C4--5 || 1790818 || UDP-glycosyltransferase 35a || 86D8 IPR002213 ' UDP-glucoronosyl and UDPglucosyl transferase SCOP:53756 ' UDPGlycosyltransferase/glycogen phosphorylase; Ugt35a|FBgn0026315|ppCT20642|FBan0006644 UDPglucuronosyltransferase ; GO:0003981 ; -0,82 -0,82 CT22631.A CT26738.A CT30101.A CT15029.A EC:2.4.1.17 | ISS UDP-glycosyltransferase ; GO:0008194 | NAS UDPglucuronosyltransferase ; GO:0003981 ; EC:2.4.1.17 | ISS with MGD:Ugt2b5; MGI:MGI:98900::UDPglucuronosyltransferase | UDPglycosyltransferase || 86D8-86D8 || 1761214 || || 91B6 IPR002350 ' Kazal-type serine protease inhibitor family SCOP:57467 ' Ovomucoid/PCI-1 like inhibitors; CG7695|FBgn0038631|ppCT22631|FBan0007695 || 91B6 || 1786576 || Calreticulin || Calreticulin 85E1 endoplasmic reticulum ; GO:0005783 | NAS endoplasmic reticulum lumen ; GO:0005788 | ISS with SWISS-PROT:P15253 IPR001580 ' Calreticulin family calcium binding ; GO:0005509 | ISS with SWISSPROT:P15253::calcium ion binding | endoplasmic reticulum lumen || 85E1 || 1782737 || NEST:bs23g10 || 70B2--3 || 70B2--3 || 1788910 || Ribosomal protein L13 || Ribosomal protein L13 30F5 protein biosynthesis ; GO:0006412 | ISS with SWISSPROT:P41123 60S ribosomal subunit ; GO:0005842 | ISS with SWISSPROT:P41123 IPR001380 ' Ribosomal protein L13e structural constituent of ribosome ; GO:0003735 | ISS with SWISS- -0,81 -0,8 -0,79 -0,79 CT13950.A CT4806.A PROT:P41123::structural constituent of ribosome | cytosolic large ribosomal subunit (sensu Eukarya) | ribosome | protein biosynthesis || 30F5 || 1781816 || CG4261, 89B helicase, 89B, BTAF1 || Helicase 89B 89A12 IPR000330 ' SNF2 related domain IPR001410 ' DEAD/DEAH box helicase IPR001650 ' Helicase Cterminal domain SCOP:48371 ' ARM repeat; Hel89B|FBgn0022787|ppCT13950|FBan0004261 SCOP:52540 ' Ploop containing nucleotide triphosphate hydrolases; Hel89B|FBgn0022787|ppCT13950|FBan0004261 helicase ; GO:0004386 | NAS ATP dependent DNA helicase ; GO:0004003 ; EC:3.6.1.3 | ISS with FLYBASE:brm; FB:FBgn0000212 ATP::helicase | ATP dependent DNA helicase || 89A11 || 1775216 || warts || protein serine/threonine kinase | G1/S transition of mitotic cell cycle | negative control of cell proliferation | cell shape control | protein amino acid phosphorylation | imaginal disc growth | eye morphogenesis (sensu Drosophila)::warts 100A5 G1/S transition of mitotic cell cycle ; GO:0000082 | IGI G1/S transition of mitotic cell cycle ; GO:0000082 | inferred from mutant phenotype cell shape control ; GO:0008360 | inferred from mutant phenotype eye morphogenesis (sensu Drosophila) ; GO:0007456 | inferred from -0,78 -0,78 CT14979.A CT22295.A CT20965.A CT1116.A mutant phenotype imaginal disc growth ; GO:0007446 | inferred from mutant phenotype negative control of cell proliferation ; GO:0008285 | inferred from mutant phenotype IPR0 || 100A5 || 1766390 || CG18138 || 65E5 IPR003104 ' Formin Homology 2 Domain actin binding ; GO:0003779 | ISS || || 1766205 || || 28D3 defense response ; GO:0006952 | NAS integral plasma membrane protein ; GO:0005887 | NAS IPR002159 ' CD36 family scavenger receptor ; GO:0005044 | NAS::scavenger receptor | integral plasma membrane protein | defense response || 28D3 || 1782565 || CG6756, CG6756, CG6756, dtom70, Translocase of outer membrane 70 || 33B11--13 mitochondrial outer membrane translocase complex ; GO:0005742 | ISS with SGD:TOM72; SGDID:L0003252 SCOP:48452 ' Tetratricopeptide repeat (TPR); CG6756|FBgn0032397|ppCT20965|FBan0006756::mitochondrial outer membrane translocase complex || 33B11--13 || 1771132 || || 3-oxoacid CoA-transferase::62B12 IPR001618 ' Coenzyme A transferase SCOP:53316 ' Glutaconate-CoA transferase subunits; CG1140|FBgn0035298|ppCT1116|FBan0001140 3-oxoacid CoAtransferase ; GO:0008260 ; EC:2.8.3.5 | ISS with SWISS-PROT:Q29551 || 62B12-62B12 -0,76 -0,76 -0,75 -0,73 CT13376.A CT27308.A CT13332.A CT30099.A || 1788274 || CG4029, CG4029, E(var)631, Dom, l(3)06142, 5295, l(3)06439, Domina, Dwhn, Whn, j || chromatin binding | transcription factor | polytene chromosome | polytene chromosome chromocenter | nucleus | nucleolus | establishment and/or maintenance of chromatin architecture | transcription | asymmetric protein localization | eye morphogenesis (sensu Drosophila) | wing morphogenesis | neuroblast determination::jumeau 86B1 transcription ; GO:0006350 | ISS with WB:lin-31 nucleolus ; GO:0005730 | inferred from direct assay nucleus ; GO:0005634 | inferred from direct assay polytene chromosome ; GO:0005700 | inferred from direct assay polytene chromosome chromocenter ; GO:0005701 | inferred from direct assay IPR001766 ' Fork head domain transcription factor ; GO:0003700 | ISS transcription factor ; GO:0003700 | nontraceable author s || 86B1 || 1789160 || CG9660, l(2)05527, l(2)k08224, l(2)K08224, BA34, BcDNA:LD27161, l(2)01361 || toucan 23D1--2 || 23D1--2 || 1788333 || CG4015, CG4015, CG4015, EG:140G11.3 || || 3C9-3C9 || 1778609 || derailed || derailed 37C7 axon guidance ; GO:0007411 | inferred from mutant phenotype protein amino acid -0,73 -0,72 -0,72 -0,71 CT30202.A CT34396.A CT14916.A CT11529.A phosphorylation ; GO:0006468 | NAS plasma membrane ; GO:0005886 | ISS IPR000719 ' Eukaryotic protein kinase IPR001245 ' Tyrosine kinase catalytic domain IPR003306 ' WIF domain transmembrane receptor protein tyrosine kinase ; GO:0004714 ; EC:2.7.1.- | ISS protein tyrosine kinase ; GO:0004713 ; EC:2.7.1.1::protein tyrosine kinase | transmembrane receptor protein tyrosine kinase | plasma membrane | axon guidance | protein amino acid phosphorylation || 37C7 || 1789015 || Furin 1 || Furin 1 96D2--4 plasma membrane ; GO:0005886 | inferred from direct assay plasma membrane ; GO:0005886 | ISS with FLYBASE:Fur2; FB:FBgn0004598 plasma membrane ; GO:0005886 | ISS with HUGO:PACE; OMIM:136950 plasma membrane ; GO:0005886 | ISS with SGD:KEX2; SGDID:S0005182 IPR000209 ' Serine proteases, subtilase family IPR002174 ' Furin-like cysteine rich region IPR002884 ' Proprotein convertas::Golgi stack | kexin | proteolysis and peptidolysis | furin | Golgi membrane, integral protein | integral membrane protein || 96D2-96E1 || 1785644 || || 1D1 || 1D1 || 1764012 || || 50A1 || 49F8--9 || 1783310 || Protein phosphatase V || Protein phosphatase V 5F4 cell cycle control ; -0,7 -0,7 -0,69 -0,68 CT26408.A CT28245.A CT2332.A GO:0000074 | IGI with SGD:SIT4; SGDID:S0002205 protein amino acid dephosphorylation ; GO:0006470 | ISS cytoplasm ; GO:0005737 | inferred from direct assay cytoplasm ; GO:0005737 | NAS IPR000934 ' Serine/threonine specific protein phosphatase SCOP:56300 ' Metallodependent phosphatases; PpV|FBgn0003139|ppCT11529|FBan0012217 protein serine/threonine::protein serine/threonine phosphatase | cell cycle control || 5F4 || 1776439 || betaTubulin56D || &bgr;Tubulin56D 56E1 muscle attachment ; GO:0016203 | TAS microtubule ; GO:0005874 | inferred from direct assay microtubule ; GO:0005874 | ISS structural constituent of cytoskeleton ; GO:0005200 | ISS::structural constituent of cytoskeleton | microtubule | cytoskeleton organization and biogenesis | muscle attachment || 56E1 || 1774717 || || 56D11 SCOP:53187 ' Zn-dependent exopeptidases; CG10051|FBgn0034437|ppCT28245|FBan0010051 || 56D11 || 1759804 || cg1239 || 83C1 IPR000051 ' SAM (and some other nucleotide) binding motif IPR001601 ' Generic methyl-transferase SCOP:53335 ' S-adenosyl-L-methioninedependent methyltransferases; CG1239|FBgn0037368|pp- -0,68 -0,68 -0,67 CT15756.A CT34990.A CT30887.A CT3066.A CT14770.A CT9788.A CT2332|FBan0001239 polynucleotide adenylyltransferase ; GO:0004652 ; EC:2.7.7.19 | ISS with SPTREMBL:Q9ZEC8::polynucleotide adenylyltransferase || 83C1 || 1787790 || Misexpression suppressor of ras 4 || 54D3--4 IPR000822 ' Zinc finger, C2H2 type SCOP:54713 ' Elongation factor Ts (EF-Ts), dimerization domain; MESR4|FBgn0034240|ppCT15756|FBan0004903 || 54D3--4 || 1776535 || enabled || actin binding | axon guidance | axonogenesis::enabled 56C4--6 axon guidance ; GO:0007411 | IGI with FLYBASE:robo; FB:FBgn0005631 axonogenesis ; GO:0007409 | inferred from mutant phenotype SCOP:50729 ' PH domain-like; enb|FBgn0000578|ppCT34990|FBan0015112 actin binding ; GO:0003779 | ISS || 56B5-56C1 || 1758924 || || 85C7 IPR002857 ' CXXC zinc finger SCOP:52047 ' RNI-like; CG11033|FBgn0037659|ppCT30887|FBan0011033 || 85C3--4 || 1758993 || || 83B8--9 || 83B8--9 || 1769917 || || 6D5--6 transcription factor ; GO:0003700 | ISS with PIR:A47212::transcription factor || 6D5-6D6 || 1782442 || || 24C7--8 IPR001190 ' Speract receptor -0,67 -0,66 -0,66 -0,65 -0,65 -0,65 CT40687.A CT42511.A (Scavenger receptor) SCOP:56436 ' C-type lectin-like; CG3921|FBgn0031571|ppCT9788|FBan0003921 SCOP:56487 ' Scavenger receptor cysteine-rich (SRCR) domain; CG3921|FBgn0031571|ppCT9788|FBan0003921 || 24C7--8 || 1789873 || || 73C4--5 IPR000103 ' Pyridine nucleotide-disulfide oxidoreductase class-II IPR000577 ' Carbohydrate kinase, FGGY family IPR000759 ' Adrenodoxin reductase IPR001327 ' FAD-dependent pyridine nucleotide-disulfide oxidoreductase SCOP:46548 ' alpha-helical ferredoxin; CG9674|FBgn0036663|ppCT27354|FBan0009674 SCOP:46548 ' alpha-helical ferredoxin; CG9674|FBgn0036663|ppCT40687|FBan0009674 SCOP:46548 ' alpha-helical ferredoxin; CG9674|FBgn0036663|ppCT40689|FBan0009674 SCOP:51395 '::glutamate synthase (NADPH) || 73C4--5 || 1765090 || Protein kinase 61C || Protein kinase 61C 61B1 protein amino acid phosphorylation ; GO:0006468 | ISS protein amino acid phosphorylation ; GO:0006468 | NAS IPR000719 ' Eukaryotic protein kinase IPR002290 ' Serine/Threonine protein kinase family active site protein serine/threonine kinase ; GO:0004674 ; -0,65 -0,64 CT23567.A CT14280.A CT33585.A EC:2.7.1.37 | ISS protein kinase ; GO:0004672 | NAS protein serine/threonine kinase ; GO:00::protein serine/threonine kinase | insulin receptor signaling pathway | positive regulation of cell growth | oogenesis | spermatogenesis | sex differentiation || 61B1 || 1780496 || || 47F7 || 47F7 || 1784107 || licorne || licorne 11D10 activation of MAPK ; GO:0000187 | inferred from direct assay axis determination ; GO:0007309 | inferred from mutant phenotype IPR000719 ' Eukaryotic protein kinase IPR002290 ' Serine/Threonine protein kinase family active site SCOP:56112 ' Protein kinase-like (PK-like); lic|FBgn0015763|ppCT14280|FBan0012244 protein kinase ; GO:0004672 | inferred from direct assay protein serine/threonine kinase ; GO:0004674 ; EC:2.7.1.37 | NAS receptor si::protein serine/threonine kinase | receptor signaling protein serine/threonine kinase | MAP kinase kinase | activation of MAPK | axis determination || 11D10 || 1774034 || CG14026, CG14026, str, Brk25D: BMP receptor kinase 25D, dtfr, l(2)04415, Atkv, t || protein kinase | type I transforming growth factor-beta receptor | plasma membrane | TGFbeta receptor signaling pathway | TGFbeta receptor complex assembly | protein amino acid phosphorylation | dorsal closure | wing morphogenesis | -0,64 -0,64 -0,64 CT25066.A CT30705.A anterior/posterior pattern formation, imaginal disc | tracheal system development::thickveins 25D1--2 TGFbeta receptor signaling pathway ; GO:0007179 | IGI dorsal closure ; GO:0007391 | inferred from mutant phenotype tracheal system development ; GO:0007424 | inferred from mutant phenotype wing morphogenesis ; GO:0007476 | IGI wing morphogenesis ; GO:0007476 | inferred from mutant phenotype plasma membrane ; GO:0005886 | ISS with FLYBASE:babo; FB:FBgn0011300 plasma membrane ; || 25D1--2 || 1761807 || CG12373, HL, MRP-L18, anon-49Ca, mitochondrial ribosomal protein L18 || 49D4 SCOP:53137 ' Translational machinery components; CG12373|FBgn0026741|ppCT25066|FBan0012373 || 49D4 || 1790558 || CG7090, EP(X)1565, EP1565, BcDNA:RE29909 || 8C1 IPR002198 ' Shortchain dehydrogenase/reductase (SDR) superfamily IPR002347 ' Glucose/ribitol dehydrogenase IPR003560 ' 2,3-dihydro2,3-dihydroxybenzoate dehydrogenase (EntA) SCOP:51735 ' NAD(P)-binding Rossmann-fold domains; CG10962|FBgn0030073|ppCT30705|FBan0010962 oxidoreductase, acting on the CH-OH group of donors, NAD or NADP as acceptor ; GO:0016616 ; EC:1.1.1.- | ISS with EMBL:AJ000671; -0,64 -0,63 CT37068.A CT6055.A protein_id:CAA04227::oxidoreductase, acting on the CH-OH group of donors, NAD or NADP as acceptor || 8C1-8C4 || 1785249 || CG8355, dSlit, Slit, CT21700, CT37068, slit, wdh || extracellular matrix | axon guidance | mesoderm migration | neuron differentiation | axonogenesis | gliogenesis::slit 52D7--9 axon guidance ; GO:0007411 | IGI with FLYBASE:robo; FB:FBgn0005631 axon guidance ; GO:0007411 | IPI with FLYBASE:robo; FB:FBgn0005631 extracellular matrix ; GO:0005578 | TAS IPR001881 ' Calciumbinding EGF-like domain SCOP:49899 ' Concanavalin A-like lectins/glucanases; sli|FBgn0003425|ppCT21700|FBan0008355 SCOP:49899 ' Concanavalin A-like lectins/glucanases; sli|FBgn0003425|pp-CT370 || 52C9--D1 || 1789748 || fat facets || fat facets 100F5 deubiquitylation ; GO:0006514 | inferred from direct assay ubiquitin cycle ; GO:0006512 | IGI with FLYBASE:eff; FB:FBgn0011217 ubiquitin-dependent protein degradation ; GO:0006511 | IGI with FLYBASE:Pros26; FB:FBgn0002284 cytoplasm ; GO:0005737 | inferred from direct assay IPR001394 ' Ubiquitin carboxylterminal hydrolase family 2 ubiquitin-specific protease ; GO:0004843 | TAS ubiqui::ubiquitin-specific protease | -0,63 -0,63 CT34444.A CT6816.A cytoplasm | nuclear migration | ubiquitindependent protein degradation | ubiquitin cycle | deubiquitination | cellularization | eye morphogenesis (sensu Drosophila) | mystery cell fate differentiation || 100F5 || 1777589 || CG12591, CG12591, CG12591, CT34444, Dpr-16 || 82F1 IPR003006 ' Immunoglobulin and major histocompatibility complex domain IPR003598 ' Immunoglobulin C-2 type IPR003600 ' Immunoglobulin-like SCOP:48726 ' Immunoglobulin; CG12591|FBgn0037295|ppCT34444|FBan0012591 || 82F1 || 1761682 || CG2092, CG2092, CG2092, ABP8, Ani, anillin, l(2)43Ec, Anillin, annilin, ani, scr || actin binding | microtubule binding | contractile ring | cytoplasm | nucleus | cytokinesis | cellularization::scraps 43E5 cellularization ; GO:0007349 | TAS cytokinesis ; GO:0016288 | TAS cytoplasm ; GO:0005737 | inferred from direct assay nucleus ; GO:0005634 | inferred from direct assay SCOP:50729 ' PH domain-like; scra|FBgn0004243|ppCT6816|FBan0002092 actin binding ; GO:0003779 | inferred from direct assay actin binding ; GO:0003779 | ISS microtubule binding ; GO:0008017 | inferred from direct assay actin bindi || 43E3 || 1785152 -0,62 -0,62 CT35041.A CT30599.A CT29790.A CT7518.A CT37566.A || || 36C10--11 || 36C10--11 || 1789610 || || 55E4--5 IPR000364 ' Phosphoenolpyruvate carboxykinase (GTP) SCOP:53795 ' Phosphoenolpyruvate carboxykinase (ATP-oxaloacetate carboxyliase); CG10924|FBgn0034356|ppCT30599|FBan0010924 phosphoenolpyruvate carboxykinase (GTP) ; GO:0004613 ; EC:4.1.1.32 | ISS with EMBL:AF009605::phosphoenolpyruvate carboxykinase (GTP) || 55D1-55D2 || 1771966 || BcDNA:SD11994 || 64D1 `de novo` protein folding ; GO:0006458 | ISS prefoldin ; GO:0016272 | ISS SCOP:46579 ' Prefoldin; CG10635|FBgn0035603|ppCT29790|FBan0010635 cochaperonin ; GO:0003772 | ISS::prefoldin | 'de novo' protein folding | co-chaperonin || 64D1 || 1773930 || CG2257, CG2257, dUbc-E2H || 7D8 IPR000608 ' Ubiquitin-conjugating enzymes SCOP:54495 ' Ubiquitin conjugating enzyme; Ubc-E2H|FBgn0029996|ppCT41464|FBan0002257 SCOP:54495 ' Ubiquitin conjugating enzyme; UbcE2H|FBgn0029996|ppCT7518|FBan0002257 ubiquitin conjugating enzyme ; GO:0004840 | ISS with NCBI_gi:4507783::ubiquitin conjugating enzyme || 7D8 || 1789607 || betaTubulin56D || &bgr;Tubulin56D 56E1 -0,61 -0,6 -0,6 -0,6 -0,6 CT16889.A CT33841.A muscle attachment ; GO:0016203 | TAS microtubule ; GO:0005874 | inferred from direct assay microtubule ; GO:0005874 | ISS structural constituent of cytoskeleton ; GO:0005200 | ISS::structural constituent of cytoskeleton | microtubule | cytoskeleton organization and biogenesis | muscle attachment || 56E1 || 1781702 || CG5408, CG5408, CG5408, CG5408, CG5408, tribbles || 77C1 cell cycle control ; GO:0000074 | inferred from mutant phenotype IPR000719 ' Eukaryotic protein kinase SCOP:56112 ' Protein kinase-like (PK-like); trbl|FBgn0028978|ppCT16889|FBan0005408 protein serine/threonine kinase ; GO:0004674 ; EC:2.7.1.37 | ISS NOT protein serine/threonine kinase ; GO:0004674 ; EC:2.7.1.37 | ISS::protein serine/threonine kinase | cell cycle control || 77C1 || 1776217 || CG14226, CG14226, CG14226, CG14226, CG14226, l(1)G0282, l(1)G0218, l(1)G0264, l || 18D13--E1 JAK-STAT cascade ; GO:0007259 | IGI with FLYBASE:Stat92E; FB:FBgn0016917 JAKSTAT cascade ; GO:0007259 | IGI with FLYBASE:os; FB:FBgn0004956 plasma membrane ; GO:0005886 | ISS with HUGO:CNTFR; OMIM:118946 plasma membrane ; GO:0005886 | ISS with HUGO:LIFR; OMIM:151443 protein tyrosine phosphatase ; GO:0004725 ; EC:3.1.3.48 | -0,6 -0,59 CT25886.A CT21891.A CT17356.A CT28157.A CT28677.A NAS::protein tyrosine phosphatase | interleukin receptor | transmembrane receptor | plasma membrane | JAK-STAT cascade | protein amino acid dephosphorylation | blastoderm segmentation | tracheal system development | morphogenesis of an epithelium || 18D13--E1 || 1787808 || CG9012, CG9012, CG9012, CG9012, l(1)VI, chc, CLH, clathrin, l(1)G0438, D-Chc, CH || Clathrin heavy chain 13F5--7 neurotransmitter release ; GO:0007269 | NAS synaptic vesicle coating ; GO:0016183 | TAS clathrin vesicle coat ; GO:0030125 | TAS coated pit ; GO:0005905 | TAS coated vesicle ; GO:0030135 | TAS synaptic vesicle ; GO:0008021 | TAS SCOP:48371 ' ARM repeat; Chc|FBgn0000319|ppCT25886|FBan0009012 SCOP:48452 ' Tetratri::clathrin coat of synaptic vesicle | coated pit | neurotransmitter release || 13F5--7 || 1761200 || || 66C8 || 66C7--8 || 1769436 || CT17356 || 19B3 SCOP:57196 ' EGF/Laminin; CG9572|FBgn0031089|ppCT17356|FBan0009572 || 19B3 || 1766533 || || 98E2 IPR001604 ' DNA/RNA nonspecific endonuclease SCOP:54060 ' HisMe finger endonucleases; CG9989|FBgn0039593|ppCT28157|FBan0009989 || 98E2 || 1773713 || || 37E4 SCOP:55811 ' Nucleoside -0,59 -0,59 -0,59 -0,59 -0,59 CT6916.A CT13057.A CT33231.A triphosphate pyrophosphorylase (MutT); CG10194|FBgn0032790|ppCT28677|FBan0010194 || 37E4 || 1787153 || || 9D3 SCOP:53474 ' alpha/betaHydrolases; CG2124|FBgn0030217|ppCT6916|FBan0002124 || 9D3 || 1782620 || CG3922, CG3922, M(3)i, M(3L)i, M(3)i<up>55</up>, RPS17, M(3L)i<up>55</up>, M(3)6 || Ribosomal protein S17 67B4 protein biosynthesis ; GO:0006412 | ISS with MGD:Rps17; MGI:MGI:1309526 40S ribosomal subunit ; GO:0005843 | ISS with MGD:Rps17; MGI:MGI:1309526 IPR001210 ' Ribosomal protein S17e structural constituent of ribosome ; GO:0003735 | ISS with MGD:Rps17; MGI:MGI:1309526::structural constituent of ribosome | ribosome | protein biosynthesis | cytosolic small ribosomal subunit (sensu Eukarya) || 67B5 || 1787212 || CG13755, CG12495, CG13754, CG2385, CG8278, CG13753, CG13752, CG33141, CG18464, C || 44F1--2 larval visceral muscle development ; GO:0007523 | inferred from mutant phenotype myoblast fusion ; GO:0007520 | inferred from mutant phenotype plasma membrane ; GO:0005886 | inferred from direct assay plasma membrane ; GO:0005886 | ISS with EMBL:AF035385 IPR003598 ' Immunoglobulin C-2 type IPR003600 ' Immunoglobulin-like SCOP:48726 ' -0,58 -0,58 -0,57 CT15057.A CT20895.A CT17874.A CT42623.A Immunoglobulin; sns|FBgn0024189|ppCT33230|FBan0013753 SCOP:48726 ' Immunoglobulin; sns|FBgn0024189|ppCT3323::cell adhesion molecule | plasma membrane | myoblast fusion | larval visceral muscle development || 44F1 || 1776519 || melted || 65E6 SCOP:48371 ' ARM repeat; melt|FBgn0023001|ppCT15057|FBan0008624 SCOP:50729 ' PH domain-like; melt|FBgn0023001|ppCT15057|FBan0008624 || 65E6 || 1787325 || || 33B9 SCOP:50978 ' Trp-Asp repeat (WD-repeat); CG6734|FBgn0032395|ppCT20895|FBan0006734 sphingomyelin phosphodiesterase activator ; GO:0016230 | ISS with NCBI_gi:4505465::sphingomyelin phosphodiesterase activator || 33B8--9 || 1761231 || ariadne || ariadne 16F7 cytoplasm ; GO:0005737 | NAS SCOP:57850 ' RING finger domain, C3HC4; ari1|FBgn0017418|pp-CT17874|FBan0005659 ubiquitin-protein ligase ; GO:0004842 ; EC:6.3.2.19 | NAS::cytoplasm | ubiquitinprotein ligase || 16F7 || 1763071 || discs overgrown || circadian rhythm | sleep | response to cocaine (sensu Insecta) | ecdysteroid release, regulation | imaginal disc growth | cell communication | casein kinase I | protein serine/threonine kinase::discs overgrown 100B2 cell communication ; GO:0007154 | inferred -0,56 -0,56 -0,56 -0,55 CT9850.A CT9237.A CT16149.A CT21795.A CT32924.A from mutant phenotype circadian rhythm ; GO:0007623 | inferred from mutant phenotype circadian rhythm ; GO:0007623 | IPI ecdysteroid release, regulation ; GO:0007555 | inferred from mutant phenotype imaginal disc growth ; GO:0007446 | inferred from mutant phenotype response to cocaine (sensu Insecta) ; GO:0008341 | inferred from mutant phenotype IPR000719 ' Eukaryotic protein kinase IPR0 || 100B2 || 1779666 || || 3D5 || 3D6 || 1787368 || CG2766, CG2716, CG2766, CG2766, CG2766, EG:BACN33B1.2 || 3B6 || 3B6 || 1762367 || LD24073p || 72D10 IPR000063 ' Thioredoxin SCOP:52833 ' Thioredoxin-like; CG5027|FBgn0036579|ppCT16149|FBan0005027 protein disulfide isomerase ; GO:0003756 ; EC:5.3.4.1 | ISS with SWISS-PROT:P08003::protein disulfide isomerase || 72D10-72D10 || 1772125 || || 61B2 SCOP:48726 ' Immunoglobulin; CG7047|FBgn0035103|ppCT21795|FBan0007047 SCOP:48726 ' Immunoglobulin; CG7047|FBgn0035103|ppCT42521|FBan0007047 || 61B2 || 1781885 || yippee interacting protein 3 || 59D8 IPR001353 ' Multispecific proteases of the proteasome SCOP:56235 ' N-terminal nucleophile aminohydrolases (Ntn -0,55 -0,55 -0,55 -0,55 -0,55 CT36522.A CT40150.A hydrolases); yip3|FBgn0040063|ppCT32924|FBan0013549 || 59D8 || 1763082 || armadillo || alpha-catenin binding | cytoskeletal anchor protein | zonula adherens | adherens junction | Wnt receptor signaling pathway | frizzled receptor signaling pathway | segment polarity determination | neuroblast determination::armadillo 2B14 frizzled receptor signaling pathway ; GO:0007222 | ISS with MGD:Catnb; MGI:MGI:88276 segment polarity determination ; GO:0007367 | ISS with MGD:Catnb; MGI:MGI:88276 catenin ; GO:0016342 | ISS zonula adherens ; GO:0005915 | inferred from direct assay SCOP:48371 ' ARM repeat; arm|FBgn0000117|ppCT12773|FBan0011579 SCOP:48371 ' ARM repeat; arm|FBgn0000117|ppCT36518|FBan0011579 SC || 2B14 || 1761289 || CG9181, CG9178, CG9181, dPTP61F, DPTP61F, dptp61F, PTP61F, protein tyrosine phos || Protein tyrosine phosphatase 61F 61F7 axon guidance ; GO:0007411 | IPI with FLYBASE:dock; FB:FBgn0010583 protein amino acid dephosphorylation ; GO:0006470 | inferred from direct assay cytoplasm ; GO:0005737 | inferred from direct assay nucleus ; GO:0005634 | inferred from direct assay IPR000242 ' Tyrosine specific protein -0,55 -0,54 CT31680.A CT22401.A CT37856.A CT32291.A phosphatase IPR000387 ' Tyrosine specific protein phosphatase and dual specificity protein phosphatase family SCOP:52799 ' (Phosp::protein tyrosine phosphatase | axon guidance || 61F7--62A1 || 1780173 || BcDNA:GM04393 || 64B11 UDPgalactose beta-N-acetylglucosamine beta1,3-galactosyltransferase ; GO:0008499 | ISS with EMBL:AF029792::UDP-galactose beta-N-acetylglucosamine beta-1,3galactosyltransferase || 64B11-64B11 || 1779300 || BcDNA:LD22320 || 22D1 SCOP:48371 ' ARM repeat; BcDNA:LD22320|FBgn0027509|ppCT22401|FBan0007261 || 22D1 || 1784279 || HIPK || 61C3--5 protein amino acid phosphorylation ; GO:0006468 | NAS IPR000719 ' Eukaryotic protein kinase IPR002290 ' Serine/Threonine protein kinase family active site SCOP:56112 ' Protein kinase-like (PK-like); CG17090|FBgn0035142|ppCT37856|FBan0017090 protein kinase ; GO:0004672 | NAS protein serine/threonine kinase ; GO:0004674 ; EC:2.7.1.37 | ISS with SGD:YAK1; SGDID:L0002490::protein kinase | protein serine/threonine kinase | protein amino acid phosphorylation || 61C3-5 || 1787823 || CG13072, DMPDCD-5, Programmed Cell Death gene-5, BcDNA:RE17056 || 72D10 -0,54 -0,54 -0,53 -0,52 CT36369.A CT7332.A CT9505.A apoptosis ; GO:0006915 | NAS SCOP:46950 ' Hypothetical protein MTH1615; PDCD-5|FBgn0036580|ppCT32291|FBan0013072::apoptosis || 72D10 || 1759486 || || 63B11--13 IPR000504 ' RNA-binding region RNP-1 (RNA recognition motif) SCOP:54928 ' RNA-binding domain, RBD; CG11505|FBgn0035424|ppCT36369|FBan0011505 || 63B11--13 || 1758195 || swiss cheese || brain development::swiss cheese 7D1 SCOP:51206 ' cAMP-binding domain-like; sws|FBgn0003656|ppCT7332|FBan0002212 || 7D1 || 1782405 || dpp || decapentaplegic 22F2--3 TGFbeta receptor signaling pathway ; GO:0007179 | ISS with MGD:Bmp4; MGI:MGI:88180 extracellular space ; GO:0005615 | inferred from direct assay intracellular ; GO:0005622 | inferred from direct assay IPR002405 ' Inhibin &agr; chain SCOP:57501 ' Cystineknot cytokines; dpp|FBgn0000490|ppCT9505|FBan0009885 transforming growth factor-beta receptor ligand ; GO:0005160 | ISS with MGD:Bmp4; MGI:MGI:881::transforming growth factorbeta receptor ligand | morphogen | TGFbeta receptor signaling pathway | BMP receptor signaling pathway | regulation of cell proliferation | zygotic determination of anterior/posterior axis, -0,52 -0,52 -0,52 CT16493.A CT17576.A CT35765.A CT8855.A embryo | dorsal closure | hindgut morphogenesis | imaginal disc development | genital disc metamorphosis | leg disc proximal/distal pattern formation | wing morphogenesis | wing vein morphogenesis | anterior/posterior pattern formation, imaginal disc || 22F2--3 || 1778787 || || 27F1 || 27F1 || 1783888 || CG5547, CG5547, CG5547, PECT, Phosphoethanolamine cytidylyltransferase || 34A9 IPR001994 ' Cytidylyltransferase SCOP:52374 ' Nucleotidylyl transferase; CG5547|FBgn0032482|ppCT17576|FBan0005547 SCOP:52374 ' Nucleotidylyl transferase; CG5547|FBgn0032482|ppCT37369|FBan0005547 ethanolaminephosphate cytidylyltransferase ; GO:0004306 ; EC:2.7.7.14 | ISS with EMBL:AF080568::ethanolamine-phosphate cytidylyltransferase || 34A9-34A9 || 1763014 || || 18F1 || 18F1 || 1780377 || || 82F4--5 IPR000010 ' Cysteine proteases inhibitor IPR000169 ' Eukaryotic thiol (cysteine) proteases active site IPR000668 ' Papain cysteine protease (C1) family IPR003244 ' Sarcocystatin SCOP:54001 ' Cysteine proteinases; CG12163|FBgn0037303|ppCT8855|FBan0012163 SCOP:54403 ' Cystatin/monellin; -0,51 -0,51 -0,51 -0,51 CT25262.A CT34346.A CT19718.A CG12163|FBgn0037303|ppCT41468|FBan0012163 SCOP:54403 ' Cystatin/monellin; CG12163|FBgn0037303|ppCT8855|FBan0012163 cathepsin F ; GO:0016946 ; EC:3.4.22.- | inferred from sequence simi::cathepsin F || 82F7-82F7 || 1763665 || || 76C1--2 IPR002557 ' Chitin binding domain SCOP:57424 ' Ligand-binding domain of low-density lipoprotein receptor; CG8756|FBgn0036901|ppCT25252|FBan0008756 SCOP:57424 ' Ligand-binding domain of low-density lipoprotein receptor; CG8756|FBgn0036901|ppCT25262|FBan0008756 SCOP:57424 ' Ligand-binding domain of low-density lipoprotein receptor; CG8756|FBgn0036901|ppCT25272|FBan0008756 SCOP:57625 ' Tachycitin; CG8756|FBgn0036901|ppCT25252|FBan0008756 SCOP:57625 ' Tachycitin; CG875 || 76C1--2 || 1776684 || || 84D6 || 84D6 || 1788363 || CG6303, CG6303, CG6303, dBRUCE, dBruce, dbruce, bruce || 86A7--8 antiapoptosis ; GO:0006916 | ISS with MGI:MGI:1276108 IPR000608 ' Ubiquitinconjugating enzymes SCOP:50998 ' Quinoprotein alcohol dehydrogenase; Bruce|FBgn0037808|pp- -0,5 -0,49 -0,49 CT28595.A CT7902.A CT19718|FBan0006303 SCOP:54495 ' Ubiquitin conjugating enzyme; Bruce|FBgn0037808|ppCT19718|FBan0006303 SCOP:57924 ' Inhibitor of apoptosis (IAP) repeat; Bruce|FBgn0037808|ppCT19718|FBan0006303 ubiquitin conjugating enzyme ; GO:0004840 | ISS ubiqu::apoptosis inhibitor | ubiquitin conjugating enzyme | anti-apoptosis || 86A7--8 || 1766743 || || 37E5 protein amino acid glycosylation ; GO:0006486 | NAS endoplasmic reticulum ; GO:0005783 | NAS IPR001173 ' Glycosyl transferase, family 2 SCOP:53448 ' Nucleotide-diphospho-sugar transferases; CG10166|FBgn0032799|ppCT28595|FBan0010166 dolichyl-phosphate beta-D-mannosyltransferase ; GO:0004582 ; EC:2.4.1.83 | ISS with SPTREMBL:Q9WU83::dolichyl-phosphate beta-D-mannosyltransferase | endoplasmic reticulum | protein amino acid glycosylation || 37E5 || 1767018 || pipsqueak (psq) || DNA binding::pipsqueak 47A14--B3 IPR000210 ' BTB/POZ domain IPR002197 ' Helix-turnhelix Fis-type SCOP:54695 ' POZ domain; psq|FBgn0004399|ppCT42138|FBan0002368 SCOP:54695 ' POZ domain; psq|FBgn0004399|ppCT7902|FBan0002368 || 47A14--B3 || 0,49 0,5 CT36627.A CT17084.A CT40937.A CT13388.A 1776498 || BcDNA:AT16994 || 44C6 nucleus ; GO:0005634 | ISS with SWISSPROT:P56223 IPR000327 ' 'POU' domain IPR001356 ' Homeobox domain SCOP:46689 ' Homeodomain-like; CG11641|FBgn0033288|ppCT36627|FBan0011641 SCOP:47413 ' lambda repressor-like DNA-binding domains; CG11641|FBgn0033288|ppCT36627|FBan0011641 transcription factor ; GO:0003700 | ISS with SWISSPROT:P56223::transcription factor || 44C6 || 1782102 || || 94A8--9 DNA-directed RNA polymerase III ; GO:0005666 | ISS with EMBL:U93869 DNA-directed RNA polymerase III ; GO:0003902 ; EC:2.7.7.6 | ISS with EMBL:U93869::DNA-directed RNA polymerase | DNA-directed RNA polymerase III | nucleus | DNA-directed RNA polymerase III complex | transcription, from Pol III promoter || 94A8--9 || 1781987 || small optic lobes || calpain | optokinetic behavior::small optic lobes 19F5 optokinetic behavior ; GO:0007634 | NAS IPR000169 ' Eukaryotic thiol (cysteine) proteases active site IPR001300 ' Calpain-type cysteinprotease (C2 family) calpain ; GO:0004198 ; EC:3.4.22.17 | ISS with EMBL:AF015038 || 19F5 || 1769790 || || 77E6 SCOP:52047 ' RNI-like; 0,5 0,51 0,51 0,52 CT13612.A CT9049.A CT10119.A CG4042|FBgn0037018|ppCT13388|FBan0004042 || 77E6 || 1783751 || expanded || apical plasma membrane | signal transduction | regulation of cell proliferation | imaginal disc development::expanded 21C6 SCOP:47031 ' Second domain of FERM; ex|FBgn0004583|ppCT13612|FBan0004114 SCOP:50729 ' PH domain-like; ex|FBgn0004583|ppCT13612|FBan0004114 SCOP:54236 ' Ubiquitin-like; ex|FBgn0004583|ppCT13612|FBan0004114 || 21C6 || 1782267 || CG2670, CG2670, CG2670, E, TAF55, TFIID, TAF7, Taf55: TBP-associated factor 55kD || 84E5 transcription initiation, from Pol II promoter ; GO:0006367 | ISS with HUGO:TAF7; OMIM:600573 transcription initiation, from Pol II promoter ; GO:0006367 | ISS with SGD:TAF67; SGDID:S0004840 TFIID complex ; GO:0005669 | ISS with HUGO:TAF7; OMIM:600573 TFIID complex ; GO:0005669 | ISS with SGD:TAF67; SGDID:S0004840 general RNA polymerase II transcription factor::general RNA polymerase II transcription factor | TFIID complex | transcription initiation, from Pol II promoter || 84E5-84E5 || 1785398 || || 5C7 IPR001085 ' Serine hydroxymethyltransferase (SHMT) SCOP:53383 ' PLP-dependent transferases; CG3011|FBgn0029823|pp- 0,52 0,52 0,54 CT30517.A CT17340.A CT10462.A CT5110.A CT21217.A CT10119|FBan0003011 glycine hydroxymethyltransferase ; GO:0004372 ; EC:2.1.2.1 | ISS with SWISSPROT:P35623::glycine hydroxymethyltransferase || 5C7-5C7 || 1787815 || toutatis || 48B2--C1 chromatin modeling ; GO:0006338 | NAS chromatin binding ; GO:0003682 | NAS::chromatin binding | chromatin modeling || 48B2--C1 || 1785701 || || 19A4 || 19A4 || 1789103 || CK02656, BEST:CK02656 || 21B1 IPR003439 ' ABC transporter SCOP:52047 ' RNI-like; BEST:CK02656|FBgn0025683|ppCT10462|FBan0003164 SCOP:52540 ' Ploop containing nucleotide triphosphate hydrolases; BEST:CK02656|FBgn0025683|ppCT10462|FBan0003164 ATP-binding cassette (ABC) transporter ; GO:0004009 ; EC:3.6.3.- | ISS with MGD:Abc8; MGI:MGI:107704::ATP-binding cassette (ABC) transporter || 21B1-21B1 || 1785742 || || 102D1 IPR001478 ' PDZ domain (also known as DHR or GLGF) SCOP:50156 ' PDZ domain-like; CG1783|FBgn0039919|ppCT5110|FBan0001783 || 102D1 || 1765901 || GLK/KHS1, Gene 2 || 56C8--D1 protein amino acid phosphorylation ; GO:0006468 | NAS IPR000719 ' Eukaryotic protein kinase IPR001180 ' Citron homology domain 0,54 0,55 0,55 0,55 0,55 CT15437.A CT28577.A CT7581.A IPR002290 ' Serine/Threonine protein kinase family active site SCOP:56112 ' Protein kinase-like (PK-like); CG7097|FBgn0034421|ppCT21217|FBan0007097 receptor signaling protein serine/threonine kinase ; GO:0004702 ; EC:2.7.1.- | NAS protein serine/threonine kinase ; GO:0004674 ; EC:2.7.1.37 |::protein serine/threonine kinase | receptor signaling protein serine/threonine kinase | protein amino acid phosphorylation || 56C8--D1 || 1776105 || TCTP || 86D9 || 86D9 || 1783587 || CG10160, CG10160, CG10160, LDH, Imp-L3, IMP-L3, Ldh, lactate dehydrogenase, lact || Ecdysone-inducible gene L3 65A11 glycolysis ; GO:0006096 | NAS IPR001236 ' Lactate/malate dehydrogenase IPR001557 ' L-lactate dehydrogenase SCOP:51735 ' NAD(P)binding Rossmann-fold domains; ImpL3|FBgn0001258|ppCT28577|FBan0010160 SCOP:56327 ' Lactate & malate dehydrogenases, Cterminal domain; ImpL3|FBgn0001258|ppCT28577|FBan0010160 L-lactate dehydrogenase ; GO:0004459 ; EC:1.1.1.27 | TAS L-lactate dehydrogenase ; GO:0004459 ;::L-lactate dehydrogenase | glycolysis || 65A11 || 1764456 || CG11628, CG11633, CG11628, CG11628, CG11628, CG11628, 0,57 0,57 0,58 CT21193.A CT11583.A CT18030.A GRP1/cytohesin 1, cytohesi || 39F3 SCOP:48425 ' Sec7 domain; CG11628|FBgn0032960|ppCT7581|FBan0011628 SCOP:50729 ' PH domain-like; CG11628|FBgn0032960|ppCT7581|FBan0011628 ARF guanylnucleotide exchange factor ; GO:0005086 | ISS with SWISS-PROT:Q9QX11::ARF guanyl-nucleotide exchange factor || 40A140A2 || 1782226 || DmBcDNA.GH02678, BcDNA:GH02678 || 16F1--2 intracellular protein traffic ; GO:0006886 | ISS with SWISSPROT:P46467 IPR003593 ' AAA ATPase superfamily SCOP:52540 ' P-loop containing nucleotide triphosphate hydrolases; BcDNA:GH02678|FBgn0027605|ppCT21193|FBan0006842 adenosinetriphosphatase ; GO:0004002 ; EC:3.6.1.3 | ISS with SWISSPROT:P46467::intracellular protein transport | adenosinetriphosphatase || 16F1-2 || 1769395 || CG12218, CG12218, AF145661, BcDNA:GH10646 || 8C15--16 IPR000315 ' B-box zinc finger superfamily IPR002991 ' B-box zinc finger SCOP:57850 ' RING finger domain, C3HC4; meiP26|FBgn0026206|ppCT11583|FBan0012218 || 8C15 || 1770126 || || 53A4 || 53A4 || 1773083 0,59 0,61 0,61 CT14464.A CT40024.A CT35206.A CT38157.A CT4564.A || || 14F2 nuclear pore ; GO:0005643 | ISS with EMBL:AF045567::nuclear pore || 14F214F2 || 1788557 || Z600 || Z600 71D3 || 71D3 || 1767078 || guftagu || guftagu 35C5--D1 nuclear ubiquitin ligase complex ; GO:0000152 | ISS with EMBL:AF083216; protein_id:AAD16038::nuclear ubiquitin ligase complex || 35C5--D1 || 1784701 || || 98D5 protein biosynthesis ; GO:0006412 | ISS with SGD:IFM1; SGDID:L0000854 mitochondrion ; GO:0005739 | ISS with SGD:IFM1; SGDID:L0000854 IPR000178 ' Initiation factor 2 IPR000795 ' GTP-binding elongation factor SCOP:50447 ' Translation proteins; CG12413|FBgn0039588|ppCT38157|FBan0012413 SCOP:52156 ' Initiation factor IF2/eIF5b, domain 3; CG12413|FBgn0039588|ppCT38157|FBan0012413 SCOP:52540 ' Ploop containing nucleo::protein biosynthesis | mitochondrion | translation initiation factor || 98D5 || 1776381 || || 10B3 SCOP:48350 ' GTPase activation domain, GAP; CG1657|FBgn0030286|ppCT4564|FBan0001657 RAB guanylnucleotide exchange factor ; GO:0017112 | ISS with EMBL:AJ001119; protein_id:CAA04545::RAB guanylnucleotide exchange factor || 10B3 || 1787104 0,61 0,62 0,62 0,63 0,65 CT32036.A CT24799.A CT4245.A || mitochondrial carnitine palmitoyltransferase I || carnitine Opalmitoyltransferase | mitochondrion::mitochondrial carnitine palmitoyltransferase I 47A11 mitochondrion ; GO:0005739 | ISS with EMBL:U88294 IPR000542 ' Acyltransferase ChoActase / COT / CPT family carnitine Opalmitoyltransferase ; GO:0004095 ; EC:2.3.1.21 | ISS with EMBL:U88294 carnitine O-palmitoyltransferase ; GO:0004095 ; EC:2.3.1.21 | NAS || 47A947A11 || 1771750 || Rhophilin || 13E18--F1 IPR001478 ' PDZ domain (also known as DHR or GLGF) SCOP:50156 ' PDZ domain-like; Rhp|FBgn0026374|ppCT24799|FBan0008497 GTP-RHO binding ; GO:0017049 | ISS GTP-RHO binding ; GO:0017049 | NAS GTP-RHO binding ; GO:0017049 | ISS with MGD:Grbp; MGI:MGI:1098783::GTP-Rho binding || 13E18-13E18 || 1778421 || || 43D7--E1 IPR002085 ' Zinc-containing alcohol dehydrogenase superfamily SCOP:50129 ' GroES-like; CG1600|FBgn0033188|ppCT37723|FBan0001600 SCOP:50129 ' GroES-like; CG1600|FBgn0033188|ppCT4245|FBan0001600 SCOP:51735 ' NAD(P)-binding Rossmann-fold domains; CG1600|FBgn0033188|pp- 0,65 0,65 0,65 CT22195.A CT25524.A CT8931.A CT15019.A CT37723|FBan0001600 SCOP:51735 ' NAD(P)-binding Rossmann-fold domains; CG1600|FBgn0033188|ppCT4245|FBan0001600 || 43D2--3 || 1778277 || || 90F1 single-stranded DNA binding ; GO:0003697 | ISS with EMBL:AF077048; protein_id:AAD27781.1::single-stranded DNA binding || 90F1-90F3 || 1790778 || CG8890, CG8890, Dm-gmd, GDPmannose 4,6-dehydratase || 25B8 SCOP:51735 ' NAD(P)-binding Rossmannfold domains; CG8890|FBgn0031661|ppCT25524|FBan0008890 GDP-mannose 4,6dehydratase ; GO:0008446 ; EC:4.2.1.47 | ISS GDP-mannose 4,6-dehydratase ; GO:0008446 ; EC:4.2.1.47 | ISS with NCBI_gi:4504031::GDP-mannose 4,6dehydratase || 25B8-25B8 || 1786355 || Serine protease inhibitor 43Aa || Serine protease inhibitor 43Aa 43A1 IPR000215 ' Serpins SCOP:56574 ' Serpins; Spn43Aa|FBgn0024294|ppCT8931|FBan0012172 serpin ; GO:0004868 | ISS with EMBL:U58361::serpin || 43A1-43A1 || 1770413 || || 65E5 acyl-CoA homeostasis ; GO:0042049 | ISS with SGD:ACB1; SGDID:L0000016 SCOP:47027 ' Acyl-CoA binding protein; CG8628|FBgn0035744|ppCT15019|FBan0008628 acyl-CoA binding ; 0,66 0,66 0,67 0,67 CT31190.A CT41842.A CT31960.A CT31216.A GO:0000062 | ISS with SGD:ACB1; SGDID:L0000016 diazepam-binding inhibitor ; GO:0008025 | ISS with MGD:Dbi; MGI:MGI:94865 || 65E5 || 1783197 || CG1706, CG1706, EP(2)2475, LD35207 || 43C1 || 43B2-43B3 || 1763662 || mitochondrial carnitine palmitoyltransferase I || carnitine Opalmitoyltransferase | mitochondrion::mitochondrial carnitine palmitoyltransferase I 47A11 mitochondrion ; GO:0005739 | ISS with EMBL:U88294 IPR000542 ' Acyltransferase ChoActase / COT / CPT family carnitine Opalmitoyltransferase ; GO:0004095 ; EC:2.3.1.21 | ISS with EMBL:U88294 carnitine O-palmitoyltransferase ; GO:0004095 ; EC:2.3.1.21 | NAS || 47A947A11 || 1779536 || || || || 1768466 || Misexpression Suppressor of Ras 1 || 12A9--B2 transcription ; GO:0006350 | ISS nucleus ; GO:0005634 | ISS nucleus ; GO:0005634 | ISS with EMBL:AF162853; protein_id:AAD44343.1 IPR000451 ' NF&kgr;-B/Rel/dorsal family SCOP:48726 ' Immunoglobulin; NFAT|FBgn0030505|ppCT31216|FBan0011172 SCOP:49417 ' p53like transcription factors; NFAT|FBgn0030505|ppCT31216|FBan0011172 RNA polymerase II transcription factor ; GO:0003702 | 0,69 0,72 0,72 0,73 CT34125.A CT2428.A CT39092.A CT36791.A inferre::RNA polymerase II transcription factor | transcription factor | nucleoplasm | transcription || 12A9--B2 || 1780078 || || SCOP:53920 ' Fe-only hydrogenase; CG17683|FBgn0040002|ppCT34125|FBan0017683 || || 1780824 || clone 1.37, anon-EST:Liang-1.37 || 62E8 IPR000822 ' Zinc finger, C2H2 type || 62E8 || 1783719 || CG3413, CG30504, CT11415, CT39092, connectin-like, windpipe || 58D7 plasma membrane ; GO:0005886 | NAS SCOP:52075 ' Outer arm dynein light chain 1; CG3413|FBgn0034718|ppCT11415|FBan0003413 SCOP:52075 ' Outer arm dynein light chain 1; CG3413|FBgn0034718|ppCT39092|FBan0003413 SCOP:56601 ' beta-Lactamase/D-ala carboxypeptidase; CG3413|FBgn0034718|ppCT11415|FBan0003413 SCOP:56601 ' beta-Lactamase/D-ala carboxypeptidase; CG3413|FBgn0034718|ppCT39092|FBan0003413::plasma membrane || 58D7 || 1776880 || CG11734 || 19C5--6 IPR000569 ' HECT domain (Ubiquitin-protein ligase) SCOP:50985 ' Regulator of chromosome condensation RCC1; HERC2|FBgn0031107|ppCT36791|FBan0011734 SCOP:56204 ' Ubiquitin-protein ligase E3a, Hect catalytic 0,73 0,74 0,75 0,75 CT31180.A CT7946.A CT6163.A CT30823.A CT34153.A CT12255.A CT10023.A domain (E6ap); HERC2|FBgn0031107|ppCT36791|FBan0011734 guanyl-nucleotide exchange factor ; GO:0005085 | NAS ubiquitin-protein ligase ; GO:0004842 ; EC:6.3.2.19 | NAS::ubiquitin-protein ligase | guanyl-nucleotide exchange factor || 19C519C6 || 1790744 || || 12B2 SCOP:53590 ' Nucleoside hydrolase; CG11158|FBgn0030511|ppCT31180|FBan0011158 || 12B2 || 1783421 || CG10106, CG10106, CG10106, CG10106, BcDNA:LD16071, Dm.Tsp42Ee, tetraspanin 42E, || 42E5 integral membrane protein ; GO:0016021 | ISS::integral membrane protein || 42E5 || 1767287 || 38E.1 || 38D4 || 38D4 || 1760838 || BcDNA:LD21213 || 69E4 || 69E4 || 1770263 || || || || 1765460 || || 60E1 IPR000868 ' Isochorismatase hydrolase family SCOP:52499 ' Cysteine hydrolase; CG3663|FBgn0035044|ppCT12255|FBan0003663 || 60D13 || 1759581 || twist || DNA binding | specific RNA polymerase II transcription factor | nucleus | mesoderm development | fate specification in mesoderm | mesoderm determination::twist 59D1 mesoderm determination ; GO:0007500 | TAS nucleus ; GO:0005634 | ISS with MGD:Twist; MGI:MGI:98872 IPR001092 ' Helix-loop- 0,75 0,77 0,79 0,79 0,8 0,82 0,87 CT7336.A CT12729.A CT8625.A CT42286.A helix dimerization domain IPR003015 ' Myctype, helix-loop-helix dimerization domain SCOP:47459 ' Helix-loop-helix DNA-binding domain; twi|FBgn0003900|ppCT10023|FBan0002956 specific RNA polymerase II transcription factor ; GO:0003704 | ISS with MGD:Twist; MGI:MGI:988 || 59D1 || 1785411 || || 11D8 || 11D8 || 1783802 || CG3820, CG3820, CG3820, l(2)10444, DCAN, dCAN, CAN/Nup214, DNup214 || 59C2 nuclear pore ; GO:0005643 | NAS SCOP:50960 ' TolB, C-terminal domain; Nup214|FBgn0010660|ppCT12729|FBan0003820::nuclear pore || 59C2 || 1786591 || BcDNA:GH05582 || 44E4--F1 || 44E4--F1 || 1776891 || Thioredoxin reductase-1 || Thioredoxin reductase-1 7D22--E1 NOT oxidized glutathione reduction ; GO:0006128 | inferred from direct assay thioredoxin pathway ; GO:0006125 | inferred from direct assay IPR000815 ' Mercuric reductase IPR001100 ' Pyridine nucleotide-disulfide oxidoreductase, class I IPR001327 ' FADdependent pyridine nucleotide-disulfide oxidoreductase SCOP:51905 ' FAD/NAD(P)-binding domain; Trxr1|FBgn0020653|pp-CT42286|FBan0002151 SCOP:51905 ' FAD/NAD(P)-binding domain; Trxr-1|FBgn0020653|p::glutathione 0,89 0,91 0,97 0,97 CT27543.A CT22861.A CT10886.A reductase (NADPH) | thioredoxin reductase (NADPH) | cytoplasm | oxidized glutathione reduction | thioredoxin pathway || 7D22--E1 || 1781508 || belle || ATP dependent RNA helicase::belle 85A5 IPR000629 ' ATPdependent helicase, DEAD-box IPR001410 ' DEAD/DEAH box helicase IPR001650 ' Helicase C-terminal domain ATP dependent helicase ; GO:0008026 ; EC:3.6.1.3 | ISS ATP dependent RNA helicase ; GO:0004004 ; EC:3.6.1.3 | ISS with SGD:DED1; SGDID:L0000500 || 85A585A5 || 1770422 || CG7434, CG7434, L22, RL22, PBP-12, Rpl22, rpl22, EG:BACR19J1.4, rpL22, anon-EST: || Ribosomal protein L22 1C4 protein biosynthesis ; GO:0006412 | ISS with SWISS-PROT:P50886 protein biosynthesis ; GO:0006412 | NAS 60S ribosomal subunit ; GO:0005842 | ISS with SWISS-PROT:P50886 IPR001386 ' Histone H1 and H5 family IPR002671 ' Ribosomal L22e protein family structural constituent of ribosome ; GO:0003735 | NAS structural constituent of ribosome ; GO:00037::ribosome | structural constituent of ribosome | protein biosynthesis | cytosolic large ribosomal subunit (sensu Eukarya) || 1C4 || 1769624 || || 23F3 SCOP:52540 ' P-loop containing nucleotide triphosphate hydrolases; 0,98 1,01 1,02 CT19215.A CT41718.A CT13516.A CT22059.A CG3238|FBgn0031540|ppCT10886|FBan0003238 || 23F3 || 1770432 || || 68C12 IPR000933 ' Glycosyl hydrolase family 29 (Alpha-L-fucosidase) alpha-Lfucosidase ; GO:0004560 ; EC:3.2.1.51 | ISS with SWISS-PROT:P17164 || || 1786955 || Btk family kinase at 29A || Btk family kinase at 29A 29A1--2 male genital morphogenesis (sensu Insecta) ; GO:0007485 | inferred from direct assay cytoplasm ; GO:0005737 | inferred from direct assay plasma membrane ; GO:0005886 | inferred from direct assay IPR000719 ' Eukaryotic protein kinase IPR000980 ' Src homology 2 (SH2) domain IPR001245 ' Tyrosine kinase catalytic domain IPR001562 ' Tec/Btk domain SCOP:50044 ' SH3-domain; Btk29A|FBgn0003502|ppCT24151|FBan0008049 SCOP:50729 ' PH domain-like; CG18355::receptor signaling protein tyrosine kinase | courtship behavior | determination of adult life span | head involution | male genital morphogenesis (sensu Insecta) | ring canal formation || 29A1--2 || 1790071 || lethal (2) 35Bg || lethal (2) 35Bg 35B8 || 35B8 || 1772953 || BcDNA:LD21293 || 79D1 IPR002625 ' Smr domain SCOP:52540 ' P-loop containing nucleotide triphosphate 1,04 1,06 1,06 1,07 CT31172.A CT42625.A hydrolases; BcDNA:LD21293|FBgn0027532|ppCT22059|FBan0007139 || 79D1 || 1788004 || CG11154, CG11154, &bgr;-ATPase, ATPsyn-beta, ATPB, ATP synthase beta subunit, H+ || ATP synthase-&bgr; 102F3 hydrogen-transporting ATP synthase, catalytic core ; GO:0005754 | ISS with MGD:Atp5b; MGI:MGI:107801 IPR000194 ' ATP synthase &agr; and &bgr; subunit, Nterminal IPR000793 ' ATP synthase &agr; and &bgr; subunit, C-terminal hydrogentransporting two-sector ATPase ; GO:0003936 ; EC:3.6.3.14 ; TC:3.A.2.1.- | NAS hydrogen-transporting two-sector ATPase ; GO:0003936 ; EC:3.6.3.14 ; TC:3.A.2.1.- | inferred::hydrogentransporting two-sector ATPase | mitochondrion | hydrogen-transporting ATP synthase, catalytic core (sensu Eukarya) | hydrogen transport || 102D1 || 1764540 || discs overgrown || circadian rhythm | sleep | response to cocaine (sensu Insecta) | ecdysteroid release, regulation | imaginal disc growth | cell communication | casein kinase I | protein serine/threonine kinase::discs overgrown 100B2 cell communication ; GO:0007154 | inferred from mutant phenotype circadian rhythm ; GO:0007623 | inferred from mutant phenotype circadian rhythm ; GO:0007623 | IPI ecdysteroid release, regulation ; 1,28 1,46 CT32117.A CT35613.A GO:0007555 | inferred from mutant phenotype imaginal disc growth ; GO:0007446 | inferred from mutant phenotype response to cocaine (sensu Insecta) ; GO:0008341 | inferred from mutant phenotype IPR000719 ' Eukaryotic protein kinase IPR0 || 100B2 || 1790354 || CG11992, CG11992, CG11992, CG11992, CG11992, l(3)neo36, ird4, relish, ird, rel, || 85C6--7 antibacterial polypeptide induction ; GO:0006963 | inferred from mutant phenotype antifungal polypeptide induction ; GO:0006967 | inferred from mutant phenotype nucleus ; GO:0005634 | NAS IPR000451 ' NF-&kgr;-B/Rel/dorsal family SCOP:48403 ' Ankyrin repeat; Rel|FBgn0014018|ppCT32117|FBan0011992 SCOP:48726 ' Immunoglobulin; Rel|FBgn0014018|ppCT32117|FBan0011992 SCOP:49417 ' p53like transcription factors; Rel|FBgn0014018|ppCT32117|FBan0011992::transcription factor | specific RNA polymerase II transcription factor | immune response | antibacterial polypeptide induction | antifungal polypeptide induction || 85C3 || 1788315 || || 99A9 protein amino acid dephosphorylation ; GO:0006470 | NAS SCOP:49265 ' Fibronectin type III; CG11516|FBgn0039661|ppCT35613|FBan0011516 protein tyrosine 1,47 1,54 CT42440.A CT26982.A CT42561.A phosphatase ; GO:0004725 ; EC:3.1.3.48 | NAS::protein amino acid dephosphorylation | protein tyrosine phosphatase || 99A9 || 1788238 || short stop || cytoskeletal protein binding | actin binding | microtubule binding | microtubule cytoskeleton | regulation of axon extension | microtubule-based process | tracheal system development | determination of muscle attachment site::short stop 50C12--D2 determination of muscle attachment site ; GO:0016204 | TAS microtubule-based process ; GO:0007017 | ISS with EMBL:AF150755; protein_id:AAD32244.1 IPR002048 ' EFhand family IPR003108 ' Growth-ArrestSpecific Protein 2 Domain SCOP:46966 ' Spectrin repeat; shot|FBgn0013733|ppCT39520|FBan0018076 SCOP:46966 ' Spectrin repeat; shot|FBgn0013733|ppCT42440|FBan0018076 SCOP:46966 ' Spectrin repeat; shot|FBgn0013 || 50C12-D2 || 1789288 || Daxx-like protein || Daxx-like protein 26D8--9 || 26D8--9 || 1764906 || || 56B3--5 SCOP:57850 ' RING finger domain, C3HC4; CG15105|FBgn0034412|ppCT34980|FBan0015105 || 56B3--5 || 1778267 1,83 1,86 2,21 (C) CG bound by ISWI and whose expression changes in ISWI mutant Total Larvae at least x4 fold [Induced (9%) / Repressed (90%), n=11/113] CT32761.A CT25670.A CT33047.A GENE DESCRIPTION || BcDNA:AT11049 || 61A6 || 61A6 || 1787487 || || 14A5 rRNA processing ; GO:0006364 | ISS with SWISSPROT:O42832 nucleolus ; GO:0005730 | ISS with SWISSPROT:O4283 SCOP:53335 ' Sadenosyl-L-methionine-dependent methyltransferases; CG8939|FBgn0030720|ppCT25670|FBan0008939 SCOP:55469 ' NADH oxidase/flavin reductase; CG8939|FBgn0030720|ppCT25670|FBan0008939 rRNA methyltransferase ; GO:0008649 ; EC:2.1.1.- | ISS with SWISSPROT:O42832::rRNA processing | nucleolus | rRNA methyltransferase || 14A5-14A5 || 1769197 || || 96B17 vesicle transport ; GO:0016192 | ISS with SWISSPROT:P49755 Golgi stack ; GO:0005795 | ISS with SWISSPROT:P49755 IPR000348 ' emp24/gp25L/p24 family::vesiclemediated transport | Golgi stack || Mean log2 ISWI / wild type -3,3 -2,44 -2,4 CT34378.A CT4004.A CT20766.A CT5200.A 96B17 || 1775043 || || 20A1--2 glucose 6phosphate:phosphate antiporter ; GO:0008524 ; TC:2.A.1.4.5 | ISS with EMBL:AF020813::glucose 6phosphate:phosphate antiporter || 20B1-20B1 || 1774413 || || 100B8 IPR000822 ' Zinc finger, C2H2 type SCOP:57667 ' C2H2 and C2HC zinc fingers; CG12054|FBgn0039831|ppCT4004|FBan0012054 || 100B8 || 1763384 || || 66D5 || 66D5 || 1781773 || Ecdysone receptor || DNA binding | neuronal remodeling | nucleus | ecdysteroid hormone receptor | ligand-dependent nuclear receptor | RNA polymerase I transcription factor::Ecdysone receptor 42A4--8 neuronal remodeling ; GO:0016322 | inferred from mutant phenotype nucleus ; GO:0005634 | inferred from direct assay nucleus ; GO:0005634 | NAS IPR000324 ' Vitamin D receptor IPR000536 ' Ligand-binding domain of nuclear hormone receptor IPR001628 ' C4type steroid receptor zinc finger IPR001723 ' Steroid hormone receptor IPR003069 ' Ecdysteroid receptor (1H nuclear receptor) -2,24 -2,23 -2,22 -2,09 CT34379.A CT27300.A CT42452.A SCOP:48508 ' Nuclear receptor ligand-binding domain || 42A4--8 || 1760509 || EG:114D9.2, anon-EST:Posey148 || 1F1 IPR003104 ' Formin Homology 2 Domain actin binding ; GO:0003779 | ISS::actin binding || 1F1-1F2 || 1776935 || CG9659, CG9659, CG9659, zw4, l(1)zw4, zw-4, ZW-4, zeste-white 4, EG:BACR25B3.8, || egghead 3A6 integral plasma membrane protein ; GO:0005887 | NAS SCOP:53448 ' Nucleotide-diphospho-sugar transferases; egh|FBgn0001404|ppCT27300|FBan0009659::integral plasma membrane protein || 3A6 || 1779518 || foraging || foraging 24A2--4 larval feeding behavior (sensu Insecta) ; GO:0008342 | inferred from mutant phenotype larval locomotory behavior ; GO:0008345 | inferred from mutant phenotype IPR000719 ' Eukaryotic protein kinase IPR000961 ' Protein kinase Cterminal domain IPR001245 ' Tyrosine kinase catalytic domain IPR002290 ' Serine/Threonine protein kinase family active site IPR002373 ' cAMP-dependent protein kinase IPR002374 ' cGMP- -2,08 -2,08 -2 CT42561.A dependent protein kinase SCOP:51206 ' cAMP-binding dom::protein serine/threonine kinase | cGMP-dependent protein kinase | feeding behavior | larval feeding behavior (sensu Insecta) | larval locomotory behavior || 24A2--4 || 1758619 || || 56B3--5 SCOP:57850 ' RING finger domain, C3HC4; CG15105|FBgn0034412|ppCT34980|FBan0015105 || 56B3--5 || 1778267 2,21
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