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Supplemental Table 1.
Differentially expressed genes following diactamnine exposure
Systematic
Name a
Standard
Gene
mame
YLL055W
YBL005W
PDR3
YOL151W
GRE2
YHR140W
YKL071W
YGR281W
YOR1
YLR346C
YNL160W
YGP1
YLL056C
YOR049C
YOL150C
YFR030W
YDR011W
YPL261C
YAL061W
YPL136W
YNL202W
YKL001C
RSB1
MET10
SNQ2
SPS19
MET14
YCR061W
YLR303W
YOR153W
YBL065W
MET17
PDR5
Fold
Changeb
product
34.0180 Hypothetical ORF
Zinc-finger transcription factor related to
24.4367
Pdr1p
NADPH-dependent methylglyoxal reductase
(D-lactaldehyde
dehydrogenase);
stress
24.3935 induced (osmotic, ionic, oxidative, heat shock
and heavy metals); regulated by the HOG
pathway
24.2269 Hypothetical ORF
23.7927 Hypothetical ORF
22.0427 ABC transporter
Protein of unknown function; expression
21.1357
regulated by PDR1
gp37, a glycoprotein synthesized in response
18.4927 to nutrient limitation which is homologous to
the sporulation-specific SPS100 gene
17.0376 Hypothetical ORF
Resistance to Sphingoid long-chain Base.
Putative transporter or flippase that
15.7267 translocates LCBs from the cytoplasmic side
toward the extracytoplasmic side of the
membrane.
14.8097 Hypothetical ORF
14.0085 Sulfite reductase alpha subunit
13.3661 ABC transporter
13.0429 Hypothetical ORF
13.0367 Putative polyol dehydrogenase
12.7651 Hypothetical ORF
12.5606 2,4-dienoyl-CoA reductase
11.9437 Adenylylsulfate kinase
Protein of unknown function; green
fluorescent protein (GFP)-fusion protein
11.5215
localizes to the cytoplasm in a punctate
pattern
11.3605 O-acetylhomoserine (thiol)-lyase
11.1768 Multidrug resistance transporter
10.6658 Hypothetical ORF
YER185W
YIR017C
MET28
YJR010W
YLL060C
YPR167C
MET3
GTT2
MET16
YOR328W
PDR10
YGL157W
YKL162C-A
YLR070C
YDR406W
XYL2
PDR15
YLR099C
ICT1
YFL032W
YML007C-A
YOL085C
YHR029C
YNL203C
YBR180W
DTR1
YMR107W
YMR102C
YCR010C
YNL134C
YJL028W
YAL042C-A
ADY2
YGR035C
YBR296C
PHO89
YBR294W
SUL1
YJR137C
ECM17
10.5751 Hypothetical ORF
Transcriptional
activator
in
the
10.5446
Cbf1p-Met4p-Met28p complex
10.2359 ATP sulfurylase
10.1722 Glutathione transferase
9.9444 3phosphoadenylylsulfate reductase
ABC transporter (putative)|highly similar to
9.9413
Pdr5p
Oxidoreductase,
catalyzes
NADPH-dependent reduction of the bicyclic
diketone
bicyclo[2.2.2]octane-2,6-dione
9.4784
(BCO2,6D) to the chiral ketoalcohol
(1R,4S,6S)-6-hydroxybicyclo[2.2.2]octane-2one (BCO2one6ol)
9.2599 Similar to PIR1, PIR2 and PIR3 proteins
8.8878 Xylitol Dehydrogenase
8.4551 Multidrug resistance transporter (putative)
Protein of unknown function, null mutation
leads to an increase in sensitivity to
8.3049
Calcofluor white; expression of the gene is
induced in the presence of isooctane
8.2331 Hypothetical ORF
Hypothetical ORF identified by homology.
8.2168
See FEBS Letters [2000] 487:31-36.
7.9293 Hypothetical ORF
7.8171 Hypothetical ORF
7.7313 Hypothetical ORF
7.7091 Dityrosine transporter MFS-MDR
Protein required for survival at high
7.3442
temperature during stationary phase
7.2936 Hypothetical ORF
7.2769 Transmembrane protein
7.2467
7.0916 Hypothetical ORF
7.0871 Hypothetical ORF
Protein of unknown function, potential
7.0658
Cdc28p substrate
6.1768 Na+/Pi symporter (putative)
Sulfate uptake is mediated by specific sulfate
transporters SUL1 and SUL2, which control
6.1742
the concentration of endogenous activated
sulfate intermediates.
6.1227 Sulfite reductase beta subunit
YHR139C
SPS100
6.0301
YOR348C
PUT4
5.6605
YML100W
TSL1
5.6320
YLL057C
5.5611
YDR070C
5.5200
YLR152C
YJL163C
YLR338W
5.5049
5.5020
5.4195
YMR322C
SNO4
5.3514
YDR374C
5.3125
YPL280W
5.1942
YOR391C
YNL337W
YGL156W
YOR237W
YOR152C
YKR076W
YBR067C
YJR162C
YOR214C
YMR291W
5.1747
5.1728
5.0580
5.0323
5.0234
5.0120
5.0028
4.9422
4.9337
4.9178
AMS1
HES1
ECM4
TIP1
YPL250C
YIL170W
YNL276C
YKL051W
YJL219W
YLR178C
4.8937
HXT12
SFK1
HXT9
TFS1
4.8896
4.8871
4.8543
4.8013
4.7760
Sporulation-specific cell wall maturation
protein
Proline specific permease
Similar
to
TPS3
gene
product/trehalose-6-phosphate
synthase/phosphatase complex 123 kDa
regulatory subunit
Similar
to
Fe(II)-dependent
sulfonate/alpha-ketoglutarate dioxygenase;
EC 1.14.11.17
The authentic, non-tagged protein was
localized to the mitochondria
Hypothetical ORF
Hypothetical ORF
Hypothetical ORF
Protein of unknown function, computational
analysis of large-scale protein-protein
interaction data suggests a possible role in
pyridoxine metabolism
Hypothetical ORF
Probable heat-shock chaperone and possible
cysteine protease; one of a mini-family of
homologous genes in S. cerevisiae including
YDR533C, YOR391C, and YMR322C
Hypothetical ORF
Alpha mannosidase
Similar to human oxysterol binding protein
Hypothetical ORF
ExtraCellular Mutant
Cell wall mannoprotein
Hypothetical ORF
Hypothetical ORF
Hypothetical ORF
Protein that interacts with the cytoskeleton
and is involved in chromatin organization and
nuclear transport, interacts genetically with
TCP1 and ICY1
Putative hexose permease
Hypothetical ORF
Suppressor of PI Four Kinase
Hexose permease
Lipid binding protein (putative)|supressor of
a cdc25 mutation
Hypothetical ORF
NADP-linked glutamate dehydrogenase
Hypothetical ORF
The RAD59 gene product has homology to
the Rad52 protein
YPL062W
YAL062W
YAL018C
GDH3
4.7348
4.7070
4.6713
YDL059C
RAD59
4.6651
YDL085W
YJL045W
NDE2
4.6645
4.6495 Similar to SDH1
The authentic, non-tagged protein was
4.5649
localized to the mitochondria
Involved in ubiquitin degradation pathway.
4.5090 May act as common transcription factor on
proteasomal and proteasome-related genes.
4.4973 Hypothetical ORF
Protein of unknown function; green
4.4926 fluorescent protein (GFP)-fusion protein
localizes to the cell periphery
4.4820 Involved in nitrosoguanidine resistance
Methylenetetrahydrofolate reductase (mthfr)
4.4697
(putative)
4.4563 Hypothetical ORF
S-adenosyl-L-methionine uroporphyrinogen
III transmethylase, involved in sulfate
4.3906
assimilation, methionine metabolism, and
siroheme biosynthesis
4.3691 Hypothetical ORF
4.3461 Gamma-glutamylcysteine synthetase
4.3411 Homoserine O-trans-acetylase
4.3222 Glucose permease
Multistress response protein,Jexpression
isJactivated byJa variety of xenobiotic agents
4.2886
and
environmental
or
physiological
stressesJJJ
4.2737 High affinity sulfate permease
4.2528 Inhibitor of proteinase Pep4p
1,3-beta-D-glucan
synthase
catalytic
4.1949
component
4.1943 Hypothetical ORF
4.1779 Arylformamidase
The authentic, non-tagged protein was
4.1038
localized to the mitochondria
4.0893 Exo-1,3-beta-glucanase, sporulation-specific
4.0872 Hypothetical ORF
YKR049C
YDL020C
RPN4
YGR201C
YDR034WB
YGR197C
SNG1
YGL125W
MET13
YGL007W
YKR069W
MET1
YLR050C
YJL101C
YNL277W
YOL156W
GSH1
MET2
HXT11
YOL052C-A
DDR2
YLR092W
YMR174C
SUL2
PAI3
YGR032W
GSC2
YAL069W
YJL060W
BNA3
YGR052W
YOR190W
YKR012C
SPR1
YBL101C
YPR151C
YNL305C
ECM21
YOL084W
PHM7
YPL171C
OYE3
YMR094W
CTF13
YMR096W
SNZ1
YPR150W
YHR112C
YGR059W
SPR3
YBL075C
YIL101C
YFL056C
YLR149C
YHR139C-A
YHR176W
YKL221W
SSA3
XBP1
AAD6
YHL024W
RIM4
YBL078C
ATG8
YGR044C
RME1
FMO
MCH2
YKL086W
YNR019W
ARE2
YLL016W
YOL118C
YOL064C
SDC25
YOR173W
DCS2
MET22
4.0135 ExtraCellular Mutant
3.9580
3.9504 Hypothetical ORF
Protein of unknown function, expression is
regulated by phosphate levels; green
3.9490
fluorescent protein (GFP)-fusion protein
localizes to the cell periphery and vacuole
3.9375 NADPH dehydrogenase
Subunit of the CBF3 complex, which binds to
the CDE III element of centromeres, bending
3.9372
the DNA upon binding, and may be involved
in sister chromatid cohesion during mitosis
Highly conserved 35 kDa protein that shows
3.9318 increased expression after entry into
stationary phase
3.8953 Hypothetical ORF
3.8816 Hypothetical ORF
A sporulation-specific homologue of the
3.8594 yeast CDC3/10/11/12 family of bud neck
microfilament genes; regulated by ABFI
3.8532 Heat shock protein of HSP70 family
3.8446 Transcriptional repressor
3.8424 Aryl-alcohol dehydrogenase (putative)
3.8214 Hypothetical ORF
3.8096 Hypothetical ORF
3.7783 Flavin-containing monooxygenase
3.7669 Monocarboxylate permease homologue
RNA-binding protein of the RRM class
3.7590
(putative)
Similar to LC3, a microtubule-associated
3.7426
protein from rat
Zinc finger protein|negative regulator of
3.7293 meiosis; directly repressed by a1-alpha 2
regulator
ATP-dependent cysteine sulfinic acid
3.7177
reductase
Acyl-CoA
cholesterol
acyltransferase
3.6949
(sterol-ester synthetase)
3.6731 GDP/GTP exchange factor for Ras
3.6606 Hypothetical ORF
3.6581 3(2)5-bisphosphate nucleotidase
Non-essential protein containing a HIT
3.6336
(histidine triad) motif; regulated by Msn2p,
YJR078W
YHR180W
BNA2
3.6284
3.6239
YJL079C
PRY1
3.6109
YKL225W
YAR035W
YFL014W
YAT1
HSP12
3.5973
3.5967
3.5824
YKL201C
MNN4
3.5712
YDR379C-A
3.5602
YDR010C
YNL237W
YHR138C
YGR154C
YKL178C
STE3
3.5429
3.5425
3.5242
3.5186
3.5090
YJL082W
IML2
3.4914
YGL205W
YNR044W
YKL008C
YGL184C
YLR307W
POX1
AGA1
LAC1
STR3
CDA1
3.4867
3.4601
3.4555
3.4516
3.4350
YDR253C
MET32
3.4321
YGL183C
YMR272C
YMR090W
YML089C
MND1
SCS7
3.4088
3.3623
3.3597
3.3593
YLL028W
TPO1
3.3548
RTS3
VPS73
3.3234
3.3100
3.3068
YJR079W
YGR161C
YGL104C
YTP1
Msn4p, and the Ras-cAMP-cAPK signalling
pathway, transcript accumulates under
glucose limitation, similar to Dcs1pJJJ
Tryptophan 2,3-dioxygenase
Hypothetical ORF
Pathogen Related in Sc, contains homology
to the plant PR-1 class of pathogen related
proteins. The protein sequence is over 60%
identical with the Pry2p & Pry3p over 145
resid. PRY1 is >35% identical (50% similar)
to tobacco PR-1c protein.
Hypothetical ORF
Carnitine acetyltransferase
Heat shock protein 12
Required
for
the
transfer
of
mannosylphosphate to cell wall mannans.
Hypothetical ORF identified by homology.
See FEBS Letters [2000] 487:31-36.
Hypothetical ORF
Yeast putative Transmembrane Protein
Homologous to PBI2
Hypothetical ORF
A-factor receptor
Protein of unknown function, green
fluorescent protein (GFP)-fusion protein
localizes to the cytoplasm and nucleus
Fatty-acyl coenzyme A oxidase
A-agglutinin anchorage subunit
LAG1 longevity gene homolog
Cystathionine beta-lyase
Chitin deacetylase
Highly homologous to Met31p|transcriptional
regulator
of
sulfur
amino
acid
metabolism|zinc finger protein
Needed for Meiotic Nuclear Divisions
Desaturase|hydroxylase
Hypothetical ORF
Hypothetical ORF
Plasma membrane-bound exporter, involved
in the detoxification of excess spermidine
Hypothetical ORF
Hypothetical ORF
YHR217C
YML083C
YGR243W
YER109C
YBR072W
FLO8
HSP26
YDR403W
DIT1
YPL067C
YML125C
YMR323W
YPL281C
ERR2
YDR073W
SNF11
YNL195C
YIL074C
YBL102W
SER33
SFT2
YMR191W
YLR364W
YBR213W
YLR327C
YLR247C
YJL172W
YCL023C
YGR087C
YMR208W
MET8
CPS1
PDC6
ERG12
YER091C
MET6
YOR230W
YMR017W
YGR043C
YOL119C
YCL041C
WTM1
SPO20
MCH4
3.3060 Hypothetical ORF
3.2971 Hypothetical ORF
The authentic, non-tagged protein was
3.2876
localized to mitochondria
3.2763 Transcriptional activator of FLO1 (putative)
3.2685 Heat shock protein 26
First enzyme in dityrosine synthesis in the
3.2551 outer layer of the spore wall pathway,
converting L-tyrosine to N-formyl-L-tyrosine
3.2419 Hypothetical ORF
3.2220 Protein required for cell viability
3.2217 Hypothetical ORF
Protein of unknown function, has similarity
3.2112
to enolases
SWI/SNF global transcription activator
3.2086
complex component
3.1867 Hypothetical ORF
3.1851 3-phosphoglycerate dehydrogenase
3.1816 Similar to mammalian syntaxin 5
Protein required for survival at high
3.1722
temperature during stationary phase
3.1672 Hypothetical ORF
Bifunctional
dehydrogenase
and
ferrochelatase, involved in the biosynthesis of
3.1579
siroheme; also involved in the expression of
PAPS reductase and sulfite reductaseJJJ
3.1574 Hypothetical ORF
3.1571 Hypothetical ORF
3.1555 Carboxypeptidase yscS
3.1514 Hypothetical ORF
3.1508 Pyruvate decarboxylase isozyme
3.1412 Mevalonate kinase
Vitamin
B12-(cobalamin)-independent
isozyme of methionine synthase (also called
N5-methyltetrahydrofolate
homocysteine
3.1327
methyltransferase
or
5-methyltetrahydropteroyl
triglutamate
homocysteine methyltransferase)
3.1222 Transcriptional modulator
3.1191 SNAP 25 homolog
3.0844 Hypothetical ORF
3.0805 Monocarboxylate permease homologue
3.0751 Protein required for cell viability
YAL066W
YMR297W
PRC1
YIR018W
YAP5
YBR284W
YLR112W
YOR347C
YNL331C
PYK2
AAD14
YPR049C
ATG11
YER142C
YDR059C
MAG1
UBC5
YGR019W
UGA1
YBR117C
TKL2
YIR019C
MUC1
YCL040W
YLR101C
YOL048C
YOL001W
YPR127W
YNR071C
YGL012W
YNL231C
GLK1
YOR370C
MRS6
YEL060C
YKR033C
YLR046C
YLR100W
YJL027C
YMR304W
YLR056W
PRB1
YHR057C
CPR2
YDL246C
SOR2
PHO80
ERG4
PDR16
ERG27
UBP15
ERG3
3.0744 Hypothetical ORF
3.0693 Carboxypeptidase Y (proteinase C)
bZIP
(basic-leucine
zipper)
3.0577
protein|transcription factor
3.0501 Hypothetical ORF
3.0487 Hypothetical ORF
3.0484 Pyruvate kinase, glucose-repressed isoform
3.0359 Aryl-alcohol dehydrogenase (putative)
Oligomeric, coiled-coil, peripheral membrane
3.0195 protein required for stable binding of
precursor API to its target membrane.
3.0121 3-methyladenine DNA glycosylase
3.0068 Ubiquitin-conjugating enzyme
Gamma-aminobutyrate
(GABA)
3.0004 transaminase
(4-aminobutyrate
aminotransferase)
2.9981 Transketolase, similar to TKL1
Cell surface flocculin with structure similar
2.9846 to serine/threonine-rich GPI-anchored cell
wall proteins
2.9836 Glucokinase
2.9810 Protein required for cell viability
2.9784 Hypothetical ORF
2.9775 Pho80p cyclin
2.9704 Hypothetical ORF
2.9691 Hypothetical ORF
2.9627 Sterol C-24 reductase
2.9597 Pdr17p homolog|Sec14p homolog
Rab geranylgeranyltransferase regulatory
2.9574
subunit
2.9466 Vacuolar protease B
2.9433 Hypothetical ORF
2.9386 Hypothetical ORF
2.9365 3-keto sterol reductase
2.9293 Hypothetical ORF
2.9276 Deubiquitinating enzyme (putative)
2.9274 C-5 sterol desaturase
Cyclophilin|peptidyl-prolyl
cis-trans
2.9195
isomerase (PPIase)
Protein of unknown function, computational
analysis of large-scale protein-protein
2.9092
interaction data suggests a possible role in
fructose or mannose metabolism
YPL054W
YPL154C
LEE1
PEP4
YDL024C
DIA3
YML042W
CAT2
YFL057C
AAD16
YJL037W
YER130C
YIL117C
PRM5
YAL067C
YJL016W
YBR139W
SEO1
YMR095C
SNO1
YPR006C
YDR072C
YMR306CA
YMR262W
YPL061W
ICL2
IPT1
2.7859 Hypothetical ORF
ALD6
YCR018C-A
YDR436W
PPZ2
YER004W
YOR285W
YBR212W
YPL006W
YLR217W
NGR1
NCR1
YBL064C
PRX1
YNL259C
ATX1
YAL028W
2.8716 Product of gene unknown
2.8583 Vacuolar proteinase A
Protein of unknown function, involved in
2.8444
invasive and pseudohyphal growth
2.8371 Carnitine O-acetyltransferase
Putative aryl-alcohol dehydrogenase with
similarity to P. chrysosporium aryl-alcohol
2.8347
dehydrogenase; mutational analysis has not
yet revealed a physiological role
2.8343 Hypothetical ORF
2.8302 Hypothetical ORF
Pheromone-regulated protein, predicted to
2.8228 have 1 transmembrane segment; induced
during cell integrity signalling
2.8226 Permease (putative)
2.8206 Hypothetical ORF
2.8103 Hypothetical ORF
Protein of unknown function, involved in
pyridoxine metabolism; expression is induced
2.8061
during stationary phase; may be part of a
complex that also contains Snz1p
2.8045 2-methylisocitrate lyase
2.7984 Inositolphosphotransferase 1
2.7816 Hypothetical ORF
2.7739 Aldehyde dehydrogenase
Similar to probable membrane protein
2.7729
YLR334C and ORF YOL106W
2.7608 Serine-threonine phosphatase Z
The authentic, non-tagged protein was
2.7514
localized to the mitochondria
2.7504 Hypothetical ORF
2.7470 Glucose-repressible RNA binding protein
2.7358 Transmembrane protein (putative)
2.7327 Hypothetical ORF
Also called mTPx I, a mitochondrial isoform
2.7248
of thioredoxin peroxidase (EC 1.11.1.-)
Copper
binding
homeostasis
protein
2.7202
(putative)
Exhibits physical and genetic interactions
2.6986 with FRT1 and genetic interactions with
TCP1; contains a C-terminal transmembrane
YPL185W
YGR066C
YKR102W
YOL099C
YJL038C
YAR070C
YGL180W
YPL018W
YML058WA
YCR023C
YLR054C
YOR124C
YMR315W
YLL063C
YDR256C
YPL036W
YDL130WA
YKL202W
YLR041W
2.6964
2.6954
FLO10
2.6924
ATG1
CTF19
2.6867
2.6805
2.6797
2.6773
2.6751
HUG1
2.6703
AYT1
CTA1
PMA2
2.6634
2.6568
2.6562
2.6547
2.6516
2.6495
2.6492
STF1
2.6444 ATPase stabilizing factor
UBP2
YMR306W
FKS3
YDR281C
PHM6
YIR016W
YBR241C
YNL036W
YPL272C
YMR196W
YIL056W
YPL052W
YBR124W
YJR025C
YMR097C
YOL129W
YOR393W
domain and shows localization to the plasma
membrane, the ER, and cytoplasmic vesicular
or granule-like structures
Hypothetical ORF
Hypothetical ORF
Protein with similarity to flocculation protein
Flo1p
Hypothetical ORF
Hypothetical ORF
Hypothetical ORF
Protein kinase
Kinetochore protein
Protein involved in the Mec1p-mediated
checkpoint pathway that responds to DNA
damage or replication arrest, transcription is
induced by DNA damage
Hypothetical ORF
Outer Spore Wall
Ubiquitin-specific protease
Hypothetical ORF
Transacetylase
Catalase A
Plasma membrane ATPase
NCE103
BNA1
MTG1
VPS68
ERR1
2.6440 Hypothetical ORF
2.6327 Hypothetical ORF
Protein with similarity to Gls1p and Gls2p
2.6261
(GB:Z49212)
Protein of unknown function, expression is
2.6238
regulated by phosphate levels
2.6011 Hypothetical ORF
2.5888 Hypothetical ORF
2.5837 Carbonic anhydrase-like protein
2.5761 Hypothetical ORF
2.5730 Hypothetical ORF
2.5729 Hypothetical ORF
2.5614 Hypothetical ORF
2.5605 Hypothetical ORF
2.5533 3-hydroxyanthranilic acid dioxygenase
2.5518 GTPase
2.5485
2.5370 Enolase homolog
YGR153W
YBR280C
YGL141W
YFL063W
HUL5
2.5362
2.5357
2.5299
2.5281
YOL047C
2.5280
YHL037C
YHL042W
YBR053C
YBR105C
YIL010W
VID24
DOT5
2.5269
2.5192
2.5165
2.5112
2.5086
YML132W
COS3
2.5084
YNR058W
BIO3
2.5073
YFL062W
COS4
2.5067
YLR099WA
YER138WA
YIR034C
YIR028W
LYS1
DAL4
YKR050W
TRK2
YIL048W
YIR027C
NEO1
DAL1
YOR316C
COT1
2.5057
Hypothetical ORF
Hypothetical ORF
Ubiquitin ligase (E3)
Hypothetical ORF
Protein of unknown function; green
fluorescent protein (GFP)-fusion protein
localizes to the cytoplasm in a punctate
pattern
Hypothetical ORF
Hypothetical ORF
Hypothetical ORF
Peripheral vesicle membrane protein
EC 1.11.1.Protein of unknown function, member of a
family
of
conserved,
often
subtelomerically-encoded proteins
7,8-diamino-pelargonic
acid
aminotransferase (DAPA) aminotransferase
Protein of unknown function, member of a
family
of
conserved,
often
subtelomerically-encoded proteins
Hypothetical ORF identified by homology.
See FEBS Letters [2000] 487:31-36.
2.5053 Similar to TyB and TyA
YFR012W-A
YBR151W
APD1
YBR302C
COS2
YBR062C
YJR151C
YNL156C
DAN4
2.5045 Saccharopine dehydrogenase
2.5036 Allantoin permease
Low affinity potassium transport|membrane
2.4989
protein
2.4983 P-type ATPase
2.4971 Allantoinase
Vacuolar transporter that mediates zinc
2.4947 transport into the vacuole; overexpression
confers resistance to cobalt and rhodium
Hypothetical ORF identified by homology.
2.4939
See FEBS Letters [2000] 487:31-36.
2.4884 Actin patches distal
Protein of unknown function, member of a
2.4872 family
of
conserved,
often
subtelomerically-encoded proteins
2.4808 Hypothetical ORF
2.4791 Cell wall mannoprotein
2.4696 Protein of unknown function, potential
YFL015C
YMR009W
YPR198W
2.4620
2.4545
SGE1
YBR293W
2.4434
2.4426
YER069W
ARG5,6
2.4400
YPL135W
ISU1
2.4261
YPR184W
GDB1
2.4248
YKL103C
YKL053W
YJL216C
YIL153W
YBR008C
YLR267W
YDR476C
YNL338W
YGR060W
YDR259C
YOR142WA
YDL159WA
YOR040W
YML007W
YDR095C
YPL277C
YPL113C
LAP4
2.4176
2.4034
2.4018
2.4011
2.3968
2.3912
2.3848
2.3827
2.3799
2.3760
GLO4
YAP1
2.3615
2.3606
2.3581
2.3563
2.3536
YJL170C
ASG7
2.3508
YOR374W
YMR175W
YNL274C
ALD4
SIP18
2.3491
2.3465
2.3460
YML048W
GSF2
2.3420
YIL046W
MET30
2.3395
RRD1
FLR1
ERG25
YAP6
2.3759
2.3625
homolog of mammalian Insig 1
Hypothetical ORF
Hypothetical ORF
Multi-copy suppressor of gal11 null; member
of drug-resistance protein family
Hypothetical ORF
N-acetyl-gamma-glutamyl-phosphate
reductase and acetylglutamate kinase
Iron-sulfur cluster nifU-like protein
Glycogen debranching enzyme; the enzyme
that debranches the glycogen having a
glucanotranferase + 1-6amyloglucosidase
activity
Vacuolar aminopeptidase ysc1
Hypothetical ORF
Hypothetical ORF
Resistant to Rapamycin Deletion
major facilitator transporter
Bypass of PAM1
Hypothetical ORF
Hypothetical ORF
C-4 sterol methyl oxidase
bZIP protein
TyA Gag protein; the main structural
constituent of virus-like particles (VLPs)
Hypothetical ORF identified by homology.
See FEBS Letters [2000] 487:31-36.
Glyoxylase-II
jun-like transcription factor
Hypothetical ORF
Hypothetical ORF
Putative dehydrogenase
An a-specific gene that is induced to a higher
expression level by alpha factor
aldehyde dehydrogenase
Salt-Induced Protein
Putative hydroxyisocaproate dehydrogenase
ER localized integral membrane protein that
may promote secretion of certain hexose
transporters, including Gal2p; involved in
glucose-dependent repression
Contains five copies of WD40 motif and
interacts with and regulates Met4p
YDR055W
PST1
2.3394
YKL210W
YPL114W
YOR134W
YOR220W
YJR020W
UBA1
2.3354
2.3335
2.3323
2.3291
2.3286
BAG7
YDR533C
YDL169C
YJR159W
2.3261
UGX2
SOR1
2.3153
2.3149
YNL045W
2.3089
YDL086W
YBL107WA
YHR096C
YIL012W
YOL158C
YAL051W
YDR216W
YFR012W
YDL085C-A
YLL061W
YCR060W
YLR281C
YBL103C
2.3067
the gene product has been detected among
the proteins secreted by regenerating
protoplasts
Ubiquitin activating enzyme e1
Hypothetical ORF
GTPase activating protein (GAP)
Hypothetical ORF
Hypothetical ORF
Protein crystal structure indicates structural
and functional homology to E. coli Hsp31, a
chaperone and putative cysteine protease;
expression upregulated on heat-shock and
oxidative stress; one four homologous genes
in S. cerevisiae
Product of gene unknown
Sorbitol dehydrogenase, sorbitol-induced
Similar to human LTA4 hydrolase but in vivo
substrates not yet defined.
Hypothetical ORF
2.3037 Similar to TyA and TyB proteins
HXT5
ENB1
OAF1
ADR1
MMP1
RTG3
YDL123W
SNA4
YGR260W
TNA1
YPL150W
YDR170WA
YDL210W
UGA4
YER044C
ERG28
2.2998
2.2981
2.2929
2.2865
2.2836
2.2814
2.2802
2.2785
2.2756
2.2713
2.2670
hexose transporter
Hypothetical ORF
enterobactin transporter
transcription factor
positive transcriptional regulator
Hypothetical ORF
Hypothetical ORF
High affinity S-methylmethionine permease
Hypothetical ORF
Hypothetical ORF
Phosphoprotein
Protein of unknown function, localized to the
2.2668
vacuolar outer membrane
High affinity nicotinic acid plasma
2.2650
membrane permease
2.2646 Hypothetical ORF
2.2643 Ty ORF
2.2635 GABA-specific transport protein
Endoplasmic reticulum membrane protein,
2.2606 may facilitate protein-protein interactions
between the Erg26p dehydrogenase and the
YPR026W
YAR066W
YBR132C
YMR046WA
YIL030C
YPL205C
ATH1
SSM4
2.2427
2.2399
YLR256W
HAP1
2.2389
YDL215C
YOL100W
YFR047C
YNL034W
YBR001C
YCL042W
YER062C
GDH2
PKH2
BNA6
HOR2
2.2385
2.2347
2.2315
2.2285
2.2278
2.2263
2.2245
YNL250W
RAD50
2.2228
YJR039W
YMR087W
YLL058W
YEL035C
YPL035C
YOL002C
YNR077C
YKL091C
YJR004C
YFL011W
AGP2
2.2570
2.2532
2.2472
2.2446
NTH2
SAG1
HXT10
2.2221
2.2212
2.2147
2.2146
2.2146
2.2135
2.2125
2.2101
2.2098
2.2092
YAR027W
UIP3
2.2081
YER119C
YFR003C
YNL155W
YER035W
YLR280C
YBR012C
YNR062C
YLL065W
AVT6
YPI1
2.2060
2.2004
2.1995
2.1990
2.1977
2.1961
2.1908
2.1905
UTR5
EDC2
Erg27p 3-ketoreductase and/or tether these
enzymes to the ER
Acid trehalase
Hypothetical ORF
Plasma membrane carnitine transporter
Similar to probable membrane protein
YLR334C and ORF YOL106W
Integral membrane protein
Hypothetical ORF
Zinc finger transcription factor of the
Zn(2)-Cys(6) binuclear cluster domain type
NAD-dependent glutamate dehydrogenase
Pkb-activating Kinase Homologue
Quinolinate phosphoribosyl transferase
Hypothetical ORF
Neutral trehalase
Hypothetical ORF
DL-glycerol-3-phosphatase
Mre11-Rad50-Xrs2 protein complex member
involved in joining double-stranded breaks
and DNA recombination
Hypothetical ORF
Hypothetical ORF
Hypothetical ORF
Product of gene unknown
Hypothetical ORF
Involved in PHO signaling pathway
Hypothetical ORF
Sec14p homolog
Alpha-agglutinin
High affinity hexose transporter
Putative integral membrane protein of
unknown function; interacts with Ulp1p at
the nuclear periphery; member of DUP240
gene family
Asp, Glu transporter
PP1 phosphatase inhibitor
Hypothetical ORF
Enhancer of mRNA Decapping
Hypothetical ORF
Hypothetical ORF
Hypothetical ORF
Growth inhibitor
YPL206C
YGL121C
2.1880
GPG1
2.1818
YDR506C
2.1813
YPL017C
2.1794
Endoplasmic reticulum protein of unknown
function
Heterotrimeric G protein gamma subunit
mimic
Hypothetical ORF
Putative
S-adenosylmethionine-dependent
methyltransferase of the seven beta-strand
family
26S
protease
subunit
component
(putative)|ATPase
Histone acetyltransferase
6-O-methylguanine-DNA methylase
Hypothetical ORF
Hypothetical ORF
Suppressor of Exocyst Mutations; Homolog
of DSS1; similar to hypothetical protein from
S. pombe
Hypothetical ORF
very low affinity methionine permease
Arginine
specific|carbamoyl
phosphate
synthetase
Pheromone-regulated
multispanning
membrane protein involved in membrane
fusion during mating; predicted to have 5
transmembrane segments and a coiled coil
domain; localizes to the shmoo tip; regulated
by Ste12p
Hypothetical ORF
Endochitinase
Protein of unknown function that co-purifies
with lipid particles; expression pattern
suggests a role in respiratory growth;
computational analysis of large-scale
protein-protein interaction data suggests a
role in ATP/ADP exchange
Hypothetical ORF
c-terminal TMD|integral membrane protein
YKL145W
RPT1
2.1749
YPR193C
YDL200C
YIL055C
YIL067C
HPA2
MGT1
2.1733
2.1732
2.1728
2.1720
SEM1
2.1719
YLR279W
YHL036W
MUP3
2.1695
2.1691
YOR303W
CPA1
2.1652
YNL279W
PRM1
2.1632
YKL224C
YLR286C
CTS1
2.1555
2.1549
YKR046C
PET10
2.1539
PEP12
2.1538
2.1529
HOR7
2.1513 Hyperosmolarity-responsive gene
FUN34
PRE2
DNF2
2.1509
2.1502
2.1473
2.1468
YDR363WA
YPR197C
YOR036W
YMR251WA
YOR389W
YNR002C
YPR103W
YDR093W
Hypothetical ORF
Transmembrane protein (putative)
Proteasome subunit
Potential aminophospholipid translocase
YDR210W
2.1467
YMR271C
YMR170C
URA10
ALD2
2.1429
2.1396
YBR046C
ZTA1
2.1392
YNL074C
YOR227W
MLF3
2.1337
2.1329
YNL200C
YCL026C-A
2.1313
FRM2
2.1301
YOR235W
YHR190W
YKL133C
ERG9
2.1292
2.1284
2.1257
YOR035C
SHE4
2.1238
YML128C
MSC1
2.1237
YPL080C
2.1234
YFL033C
RIM15
2.1231
YGR135W
YMR180C
YOL136C
PRE9
CTL1
PFK27
2.1231
2.1210
2.1207
YGL186C
TPN1
2.1204
YLR216C
CPR6
2.1203
YER096W
YCL026C-B
SHC1
2.1176
2.1173
YER053C
YER018C
YCR089W
2.1146
SPC25
FIG2
2.1140
2.1136
Protein of unknown function; green
fluorescent protein (GFP)-fusion protein
localizes to the cell periphery
Orotate phosphoribosyltransferase 2
aldeyhde dehydrogenase
Zeta-crystallin homolog, has similarity to E.
coli quinone oxidoreductase and human
zeta-crystallin
which
has
quinone
oxidoreductase activity
Protein of unknown function
Hypothetical ORF
Hypothetical ORF; similarity to human
TGR-CL10C,
thyroidal
receptor
for
N-acetylglucosamine
Protein involved in the integration of lipid
signaling pathways with cellular homeostatis
Hypothetical ORF
Squalene synthetase
Hypothetical ORF
Required for mother cell-specific HO
expression
Protein of unknown function, green
fluorescent protein (GFP)-fusion protein
localizes to the endoplasmic reticulum; msc1
mutants are defective in directing meiotic
recombination events to homologous
chromatids
Hypothetical ORF
Trehalose-associated protein kinase related to
S. pombe cek1+
Proteasome component Y13
RNA triphosphatase
6-phosphofructo-2-kinase
Plasma membrane pyridoxine transport
protein
cyclophilin
40|peptidyl-prolyl
cis-trans
isomerase (PPIase)
sporulation-specific protein similar to Skt5p
Hypothetical ORF
Sequence similarity to mitochondrial
phosphate transporters
Spindle pole component
GPI-anchored cell wall protein (putative)
YOR255W
YLR144C
ACF2
YDR502C
SAM2
YOR321W
PMT3
YIL166C
YNL336W
COS1
YOR186W
YMR173W
DDR48
YAL034C
YKL147C
YPL170W
YEL072W
FUN19
YDR032C
PST2
DAP1
RMD6
YMR173WA
YGR065C
VHT1
YOR212W
STE4
YKL052C
ASK1
YPL223C
GRE1
YMR008C
PLB1
2.0785 Hypothetical ORF
YDL222C
YDR171W
HSP42
YKR011C
YJR161C
2.1119 Outer Spore Wall
Glucan-hydrolyzing protein that specifically
acts on 1,3-beta linkages, with an endolytic
2.1091
mode of action. necessary for actin
polymerization in permeabilized cells.
2.1048 Methionine biosynthesis regulation
Dolichyl
phosphate-D-mannose:protein
2.1028
O-D-mannosyltransferase
Hypothetical ORF, member of the Dal5p
2.1003
subfamily of the major facilitator family
Protein of unknown function, member of a
2.0944 family
of
conserved,
often
subtelomerically-encoded proteins
2.0942 Hypothetical ORF
Contains >35 repeats of the amino acid
2.0941 sequence NNNDSYGS|flocculent specific
protein
2.0889 Protein of unknown function
2.0852 Hypothetical ORF
2.0836 sterol-binding protein (putative)
2.0830 Required for Meiotic nuclear Division
Protoplasts-SecreTed protein; the gene
2.0820 product was detected among the proteins
secreted by regenerating protoplasts
COS5
2.0782 H+-biotin symporter
G protein beta subunit|coupled to mating
2.0776
factor receptor
2.0754 Associated with Spindles and Kinetochores
Hydrophilin of unknown function; stress
induced (osmotic, ionic, oxidative, heat shock
2.0734
and heavy metals); regulated by the HOG
pathway
2.0697 Phospholipase B (lypophospholipase)
The authentic, non-tagged protein was
2.0674 localized to the mitochondria; cell cortex
protein
Similar to HSP26; expression is regulated by
2.0667
stress conditions
2.0639 Hypothetical ORF
Protein of unknown function, member of a
2.0634
family
of
conserved,
often
YDR453C
TSA2
2.0633
YGL216W
YOR011W
YJL077C
KIP3
AUS1
ICS3
2.0618
2.0596
2.0589
YLR270W
DCS1
2.0543
YBR148W
YER103W
YHR145C
YSW1
SSA4
2.0515
2.0509
2.0490
YMR189W
GCV2
2.0470
YMR151W
YIM2
2.0467
YHR124W
NDT80
2.0443
YKR097W
YDL124W
PCK1
2.0416
2.0414
YDR513W
TTR1
2.0361
YCR030C
YDL128W
YLR080W
SYP1
VCX1
EMP46
2.0358
2.0358
2.0341
YKL065C
2.0335
YDR122W
KIN1
2.0328
YDR283C
GCN2
2.0319
YJL206C
YLR312C
YGR248W
YHR214W
YGR049W
YKR106W
SOL4
SCM4
2.0313
2.0305
2.0289
2.0267
2.0247
2.0243
subtelomerically-encoded proteins
Thioredoxin-peroxidase
(TPx);
reduces
H2O2 and alkyl hydroperoxides with the use
of hydrogens provided by thioredoxin,
thioredoxin reductase, and NADPH|EC
1.11.1.Kinesin-related protein
ATP-binding cassette (ABC) family
Protein of unknown function
Non-essential hydrolase involved in mRNA
decapping, may function in a feedback
mechanism to regulate deadenylation,
contains pyrophosphatase activity andJa HIT
(histidine triad)Jmotif; interacts with neutral
trehalase Nth1pJJ
Spore-specific protein
HSP70 family
Hypothetical ORF
Glycine cleavage system P subunit|glycine
decarboxylase complex P subunit|glycine
synthase P subunit
Product of gene unknown
DNA binding transcription factor that
activates middle sporulation genes
Phosphoenolpyruvate carboxylkinase
Hypothetical ORF
glutaredoxin|thioltransferase/glutathione
reductase|EC 1.20.4.1
Suppressor of Yeast Profilin deletion
vacuolar H+/Ca2+ exchanger
homolog of the Golgi protein Emp47p
Yeast endoplasmic reticulum 24 kDa
transmembrane protein
Serine/threonine protein kinase
Eukaryotic initiation factor 2 alpha
(eIF2-alpha) kinase
Hypothetical ORF
Hypothetical ORF
6-phosphogluconolactonase
Putative membrane protein
Protein that suppresses ts allele of CDC4
when overexpressed
Hypothetical ORF
YBR299W
YLR174W
YKR053C
YDR335W
MAL32
IDP2
YSR3
MSN5
2.0238
2.0232
2.0198
2.0184
YMR139W
RIM11
2.0148
YOR092W
YKL146W
YNL280C
YBL041W
YOR084W
ECM3
AVT3
ERG24
PRE7
2.0134
2.0114
2.0107
2.0106
2.0102
YGR037C
ACB1
2.0099
YMR276W
YML131W
YGR284C
YKL070W
DSK2
2.0058
2.0054
2.0039
2.0016
YBR214W
SDS24
YPR124W
CTR1
-12.5488
YOL152W
FRE7
-12.2951
YGR144W
THI4
-11.2966
YDL241W
YHR128W
FUR1
-9.3779
-8.0710
YNL112W
DBP2
-7.0214
ERV29
YPR123C
2.0010
-6.6529
YNL141W
AAH1
-6.6065
YDR399W
HPT1
-5.7893
YPL058C
YLR004C
YMR326C
YGR293C
YOR004W
PDR12
-5.5090
-5.5043
-5.1049
-4.9925
-4.8400
YCR020C
PET18
-4.8092
Maltase
NADP-dependent isocitrate dehydrogenase
DHS-1-P phosphatase
Multicopy suppressor of snf1 mutation
Required for Ime1p phosphorylation,
association of the Ime1p-Ume6p meiotic
activator, early meiotic gene expression, and
sporulation
ExtraCellular Mutant
Gln (Asn), Ile (Leu), Tyr transporter
Sterol C-14 reductase
proteasome subunit
acyl-CoA-binding protein (ACBP)/diazepam
binding inhibitor (DBI)/endozepine (EP)
ubiquitin-like protein
Hypothetical ORF
ER-Golgi transport vesicle protein
Hypothetical ORF
Similar to S. pombe SDS23, suppresses
DIS2, localized to the nucleus
Copper transport protein
Putative ferric reductase with similarity to
Fre2p; expression induced by low copper
levels but not by low iron levels
biosynthetic pathway component producing
the thiazole precursor of thiamine
Hypothetical ORF
UPRTase
ATP dependent RNA helicase|dead box
protein
Hypothetical ORF
Adenine
aminohydrolase
(adenine
deaminase)
Hypoxanthine
guanine
phosphoribosyltransferase
Multidrug resistance transporter
Hypothetical ORF
Hypothetical ORF
Hypothetical ORF
Protein required for cell viability
Protein required for respiratory growth and
stability of the mitochondrial genome
YFR055W
YGR021W
YIL119C
YLR237W
YLR214W
YBR238C
YDL182W
RPI1
THI7
FRE1
LYS20
YJL218W
YOR342C
-4.7865
-4.7753
-4.7531
-4.7428
-4.6440
-4.4464
-4.3328
-4.3186
-4.2082
Hypothetical ORF
Hypothetical ORF
Ras inhibitor
Thiamine transporter
Cupric reductase|ferric reductase
Hypothetical ORF
YDL131W (LYS21) homolog|homocitrate
synthase
Hypothetical ORF
Hypothetical ORF
Snooze: stationary phase-induced gene
family
Nuclear localization sequence binding protein
Hypothetical ORF
Translation initiation factor eIF3 subunit
Putative transmembrane domain protein
involved in cell wall biogenesis
histone H2A (HTA1 and HTA2 code for
nearly identical proteins)
transcriptional activator protein of CYC1
(component of HAP2/HAP3 heteromer)
Protein that binds to the C-terminal domain
of Hyp2p (eIF5A); has four to five
HEAT-like repeats
Hypothetical ORF
Hypothetical ORF
Malic enzyme
Purine-cytosine permease
Multicopper oxidase
Isocitrate dehydrogenase 1 alpha-4-beta-4
subunit
Hypothetical ORF
Iso-1-cytochrome c
YFL059W
SNZ3
-4.1843
YGR159C
YBR025C
YBR079C
NSR1
RPG1
-4.1661
-4.1538
-4.1105
YAL059W
ECM1
-3.9355
YBL003C
HTA2
-3.8144
YKL109W
HAP4
-3.8032
YJR070C
LIA1
-3.7979
YLR296W
YBR300C
YKL029C
YER056C
YMR058W
MAE1
FCY2
FET3
-3.7967
-3.7685
-3.6538
-3.6392
-3.6301
YNL037C
IDH1
-3.6053
CYC1
-3.5682
-3.5635
FCY22
-3.5138 purine-cytosine permease
YGR160W
YJR048W
YER060WA
YIL019W
YOR272W
YTM1
YPR100W
MRPL51
YFL060C
SNO3
-3.4930 Protein required for cell viability
-3.4728 Microtubule-associated protein
Mitochondrial ribosomal protein of the large
-3.4713
subunit
Protein of unknown function, nearly identical
to Sno2p; expression is induced before the
-3.4578
diauxic shift and also in the absence of
thiamin
YOR095C
RKI1
YDL051W
LHP1
YBR092C
YHR061C
PHO3
GIC1
YDR033W
MRH1
YGR109C
YOR101W
CLB6
RAS1
YOR108W
LEU9
YLR449W
YER001W
YDR375C
FPR4
MNN1
BCS1
YDL205C
HEM3
YNL175C
NOP13
YML056C
IMD4
YLR168C
YDR021W
FAL1
YOL124C
YPR145W
ASN1
YOL055C
THI20
YFR056C
YDR277C
YDR534C
YNL174W
MTH1
FIT1
-3.4553 Ribose-5-phosphate ketol-isomerase
Protein homologous to human La (SS-B)
-3.4480
autoantigen
-3.4417 Acid phosphatase
-3.4144 Gtpase-interacting component 1
Membrane protein related to Hsp30p;
Localized by immunofluorescence to
membranes, mainly the plasma membr.
-3.4127 punctuate
immunofluorescence
pattern
observed in buds. The nuclear envelope, but
not vacuole or mitochondrial membranes also
stained
-3.4112 B-type cyclin
-3.3774 ras homolog
Alpha-isopropylmalate
synthase
-3.3665
(2-isopropylmalate synthase)
-3.3546 Peptidyl-prolyl cis-trans isomerase (PPIase)
-3.3110 Alpha-1,3-mannosyltransferase
-3.3059 ATPase (AAA family)
Phorphobilinogen
deaminase
-3.3029
(uroporphyrinogen synthase)
Protein of unknown function, localizes to the
nucleolus and nucleoplasm; contains an RNA
-3.3023 recognition motif (RRM) and has similarity
to Nop12p, which is required for processing
of pre-18S rRNA
-3.2934 IMP dehydrogenase homolog
Possibly involved in intramitochondrial
-3.2505
sorting
-3.2247 RNA helicase (putative)|dead box protein
Putative
S-adenosylmethionine-dependent
-3.2155 methyltransferase of the seven beta-strand
family
-3.2041 asparagine synthetase
THI for thiamine metabolism. Transcribed in
the presence of low level of thiamine
-3.1914 (10-8M) and turned off in the presence of
high level (10-6M) of thiamine. Under the
positive control of THI2 and THI3.
-3.1774 Hypothetical ORF
-3.1591 Msn3p homolog (61% identical)
-3.1212 Cell wall protein involved in iron uptake
-3.1171 Hypothetical ORF
YMR006C
YNL220W
YOR203W
YDL060W
YBL039C
YJL033W
YLR073C
YGR108W
YHR020W
PLB2
ADE12
YBR240C
THI2
-3.0043
YDL050C
YOR315W
YLR269C
YDR226W
ADK1
-2.9826
-2.9715
-2.9685
-2.9368
YNL333W
SNZ2
-2.9037
YCR087C-A
YJL122W
YOR248W
YML087C
YPL199C
YKL078W
DHR2
-2.8990
-2.8801
-2.8744
-2.8693
-2.8602
-2.8596
YLR074C
BUD20
-2.8425
YOR282W
YMR319C
YHR066W
FET4
SSF1
-2.8086
-2.7919
-2.7898
YGL053W
PRM8
-2.7853
YBL029W
YKL132C
RMA1
-2.7771
-2.7726
YHR049W
FSH1
-2.7724
YDR322W
MRPL35
-2.7704
YGR061C
ADE6
-2.7680
YKL030W
TSR1
URA7
HCA4
CLB1
-3.1027
-3.0893
-3.0757
-3.0721
-3.0533
-3.0513
-3.0359
-3.0353
-3.0099
-2.7440
Lysophospholipase|phospholipase B
Adenylosuccinate synthetase
Protein required for cell viability
Twenty S rRNA accumulation
CTP synthase
RNA helicase (putative)
Hypothetical ORF
B-type cyclin
Protein required for cell viability
Transcriptional activator of thiamine
biosynthetic genes
Hypothetical ORF
Hypothetical ORF
Hypothetical ORF
Adenylate kinase
Snooze: stationary phase-induced gene
family
Hypothetical ORF
Hypothetical ORF
Hypothetical ORF
Hypothetical ORF
Hypothetical ORF
Required for 18S ribosomal RNA synthesis
Protein involved in bud-site selection; diploid
mutants display a random budding pattern
instead of the wild-type bipolar pattern
Protein required for cell viability
low affinity Fe2+ transport protein
Ssf2p homolog
Pheromone-regulated
protein
with
2
predicted transmembrane segments and an FF
sequence, a motif involved in COPII binding;
forms a complex with Prp9p in the ER
Hypothetical ORF
probable folyl-polyglutamate synthetase
Serine hydrolase that localizes to both the
nucleus and cytoplasm. Sequence similary to
Fsh2p and Fsh3p
Mitochondrial ribosomal protein of the large
subunit
5-phosphoribosylformyl
glycinamidine
synthetase
Hypothetical ORF
YNR066C
YDR496C
YGR234W
YAL025C
PUF6
YHB1
MAK16
YMR049C
ERB1
YDL062W
YPL092W
YMR290WA
YPR144C
SSU1
-2.7409
-2.7393
-2.7303
-2.7165
Hypothetical ORF
Member of the PUF protein family
flavohemoglobin
Nuclear protein (putative)
Protein required for maturation of the 25S
-2.7077 and 5.8S ribosomal RNAs; homologous to
mammalian Bop1
-2.7075 Hypothetical ORF
-2.6972 major facilitator superfamily
-2.6961 Protein required for cell viability
NOC4
YHR062C
RPP1
YOR242C
SSP2
YBR061C
TRM7
YLR196W
PWP1
YPL093W
NOG1
YML027W
YOX1
YIL036W
CST6
YNL334C
SNO2
YJL217W
YMR120C
ADE17
YPL256C
YGR145W
YHR052W
CLN2
YGL078C
DBP3
YMR081C
ISF1
YJL096W
MRPL49
CIC1
-2.6783 U3 snoRNP protein
Nuclear ribonuclease P (RNase P) protein
-2.6632
subunit
-2.6585 Sporulation SPecific
2-O-ribose
tRNA
anticodon
loop
-2.6458
methyltransferase
Periodic tryptophan proteinProtein with
periodic trytophan residues that resembles
-2.6439
members of beta-transducin superfamily
because of presence of WD-40 repeats
Homologs identified in human and
-2.6330 Trypanosoma brucei|nucleolar G-protein
(putative)
-2.6302 Homeobox-domain containing protein
basic leucine zipper (bZIP) transcription
-2.6236
factor
Protein of unknown function, nearly identical
to Sno3p; expression is induced before the
-2.6104
diauxic shift and also in the absence of
thiamin
-2.6061 Hypothetical ORF
5-aminoimidazole-4-carboxamide
-2.5958 ribonucleotide (AICAR) transformylase/IMP
cyclohydrolase
-2.5938 G1 cyclin
-2.5915 Essential protein of unknown function
-2.5775 Core interacting component 1
ATP dependent RNA helicase|dead/deah box
-2.5753
protein CA3
May regulate NAM7 function, possibly at
-2.5730
level of mRNA turnover
-2.5712 Mitochondrial ribosomal protein of the large
YKL016C
YIL096C
YER188W
ATP7
-2.5708
-2.5565
-2.5545
YGR165W
MRPS35
-2.5544
YBR093C
YDR324C
YLR395C
PHO5
UTP4
COX8
-2.5535
-2.5507
-2.5451
YNL151C
RPC31
-2.5451
YPL132W
COX11
-2.5423
YLL018C-A
COX19
-2.5411
YPL266W
YJL208C
YML094C-A
YKR039W
YDR321W
DIM1
NUC1
-2.5345
-2.5209
-2.5176
-2.5110
-2.5077
GAP1
ASP1
YOL007C
YGL171W
-2.5061
ROK1
-2.5024
YLR063W
YJL148W
YPR010C
YKL056C
RPA34
RPA135
-2.4990
-2.4974
-2.4965
-2.4929
YER006W
NUG1
-2.4884
YLR365W
YIL070C
MAM33
-2.4883
-2.4851
YJL025W
RRN7
-2.4772
YLR397C
YHR169W
YFR035C
YBR271W
AFG2
DBP8
-2.4768
-2.4666
-2.4618
-2.4516
subunit
ATP synthase d subunit
Hypothetical ORF
Hypothetical ORF
Mitochondrial ribosomal protein of the small
subunit
Acid phosphatase
U3 snoRNP protein
Cytochrome c oxidase chain VIII
HMG1-like protein|RNA polymerase III (C)
31 kDa subunit
Mitochondrial membrane protein required for
assembly of active cytochrome c oxidase,
probably involved in insertion of Cu(B) and
magnesium
Protein required for cytochrome c oxidase
assembly, located in the cytosol and
mitochondrial intermembrane space; putative
copper metallochaperone that delivers copper
to cytochrome c oxidase
Dimethyladenosine transferase
Nuclease
Hypothetical ORF
General amino acid permease
Asparaginase I|intracellular isozyme
Appears to be a structural component of the
chitin synthase 3 complex
ATP-dependent RNA helicase of the DEAD
box family; required for 18S rRNA synthesis
Hypothetical ORF
RNA polymerase I subunit A34.5
RNA polymerase I subunit
Hypothetical ORF
Nuclear GTPase involved in Ribosome
biogenesis
Hypothetical ORF
33-kDa mitochondrial acidic matrix protein
yeast Pol I core factor (CF) also composed of
Rrn11p, Rrn6p and TATA-binding protein
Similar to the CDC48 gene product
Dead box protein
Hypothetical ORF
Putative
S-adenosylmethionine-dependent
YFL017W-A SMX2
YBL031W
SHE1
-2.4502
-2.4468
YBL090W
-2.4437
MRP21
YHL013C
YOR206W
-2.4428
NOC2
YIL025C
-2.4401
-2.4400
methyltransferase of the seven beta-strand
family
snRNP G protein (human Sm-G homolog)
Product of gene unknown
Mitochondrial ribosome small subunit
component
Hypothetical ORF
Protein that forms a nucleolar complex with
Mak21p that binds to 90S and 66S
pre-ribosomes, as well as a nuclear complex
with Noc3p that binds to 66S pre-ribosomes;
both complexes mediate intranuclear
transport of ribosomal precursors
Hypothetical ORF
Responsible for most, if not all, m(1)G(9)
modification of tRNAs.
Mitochondrial ribosome recycling factor
RiboSome Assembly 2
Protein tyrosine phosphatase induced by
nitrogen starvation
Ribosomal protein S5 (putative)
14
kDa
mitochondrial
ribosomal
protein|similar to E. coli S14 protein
Heat shock transcription factor homolog
Malate dehydrogenase
Coiled-coil protein
Protein required for cell viability
SnRNP protein
Hypothetical ORF
Hypothetical ORF
Mitochondrial ribosomal protein of the large
subunit
Ribosomal protein S9A (S13) (rp21) (YS11)
Hypothetical ORF
Ribonuclease III
YOL093W
TRM10
-2.4337
YHR038W
YMR131C
RRF1
RRB1
-2.4305
-2.4299
YIR026C
YVH1
-2.4199
YBR251W
MRPS5
-2.4170
YPR166C
MRP2
-2.4133
YJR147W
YKL085W
YGL029W
YPL251W
YJR022W
YCR087W
YHL008C
HMS2
MDH1
CGR1
-2.4115
-2.4073
-2.4064
-2.4056
-2.4049
-2.4015
-2.3969
YKR085C
MRPL20
-2.3939
YPL081W
YOL014W
YMR239C
YKR081C
YLR445W
YOL077WA
YPR041W
YER070W
YBR120C
YNL300W
RPS9A
-2.3934
-2.3904
-2.3891
-2.3771
-2.3769 Hypothetical ORF
LSM8
RNT1
RPF2
ATP19
-2.3646 ATP synthase subunit k homolog
TIF5
RNR1
CBP6
-2.3640
-2.3623
-2.3589
-2.3561
Translation initiation factor eIF5
Ribonucleotide reductase, large (R1) subunit
Translational activator of COB mRNA
Hypothetical ORF
YHR183W
GND1
-2.3552
YHR092C
YGR245C
HXT4
SDA1
-2.3502
-2.3501
YOR224C
RPB8
-2.3486
YOR135C
-2.3484
YHR085W
-2.3338
YGL055W
YDL063C
OLE1
-2.3332
-2.3279
YJL158C
CIS3
-2.3241
YNL291C
MID1
-2.3185
YDR060W
MAK21
-2.3165
YDL181W
Q0045
INH1
COX1
-2.3121
-2.3060
YBR161W
CSH1
-2.3056
YNR053C
NOG2
-2.3040
YAR028W
-2.3036
YDL055C
PSA1
-2.3009
YGR169C
YCR046C
PUS6
IMG1
-2.2977
-2.2973
YNL061W
NOP2
-2.2926
YDR120C
TRM1
-2.2891
YLR265C
YKL131W
NEJ1
-2.2888
-2.2846
6-phosphogluconate
dehydrogenase,
decarboxylating;
converts
6-phosphogluconate
+
NADP
to
ribulose-5-phosphate + NADPH + CO2
High affinity glucose transporter
Severe Depolymerization of Actin
16 kDa RNA polymerase subunit (common
to polymerases I, II and III)
Hypothetical ORF
Protein of unknown function, essential for
viability, may be involved in rRNA
processing
Delta-9-fatty acid desaturase
Hypothetical ORF
Similar to Hsp150p and Pir1p, Pir2p, and
Pir3p
N-glycosylated integral plasma membrane
protein
Essential for 60s ribosome biogenesis;
involved in nuclear export of pre-ribosomes
ATPase inhibitor
Cytochrome c oxidase subunit I
Probable
catalytic
subunit
of
a
mannosylinositol
phosphorylceramide
(MIPC) synthase, forms a complex with
probable regulatory subunit Csg2p; function
in sphingolipid biosynthesis is overlapping
with that of Sur1p
part of a pre-60S complex
Putative integral membrane protein, member
of DUP240 gene family
GDP-mannose
pyrophosphorylase|mannose-1-phosphate
guanyltransferase
RNA:Psi-synthase
mitochondrial ribosomal protein
90 kDa protein homologous to a human
proliferation-associated nucleolar protein,
p120
N2,N2-dimethylguanosine-specific
tRNA
methyltransferase
Mating-type regulated component of NHEJ
Hypothetical ORF
YHL004W
MRP4
-2.2773
YCR098C
GIT1
-2.2756
YMR217W
YHR148W
YNL110C
YNL017C
YOR146W
GUA1
IMP3
NOP15
-2.2746
-2.2685
-2.2681
-2.2652
-2.2612
YPL252C
YAH1
-2.2605
YGL129C
RSM23
-2.2586
YDR087C
RRP1
-2.2584
YGL117W
-2.2568
YCL058C
FYV5
-2.2560
YER110C
YGR123C
KAP123
PPT1
-2.2556
-2.2475
YDR299W
BFR2
-2.2443
YNR018W
YIL122W
YOR334W
POG1
MRS2
-2.2438
-2.2435
-2.2421
YLR160C
ASP3-4
-2.2420
YOL164W
YHR033W
-2.2415
-2.2403
YML009C
MRPL39
-2.2403
YCR003W
YPL267W
YIL082W
MRPL32
-2.2382
-2.2355
-2.2351
YLL053C
YMR290C
YOR246C
-2.2325
HAS1
-2.2322
-2.2284
Mitochondrial
ribosomal
protein|mitochondrial ribosome 37 S subunit
component|similar to E. coli ribosomal
protein S2
Permease involved in the uptake of
glycerophosphoinositol (GroPIns)
GMP synthase
U3 snoRNP protein
Ribosome biogenesis
Hypothetical ORF
Protein required for cell viability
Iron-sulfur protein similar to human
adrenodoxin
ATPase (putative)|mitochondrial ribosome
small subunit component
Involved in processing rRNA precursor
species to mature rRNAs
Hypothetical ORF
Protein of unknown function, required for
survival upon exposure to K1 killer toxin;
involved in ion homeostasis
Karyopherin beta 4
Serine/threonine phosphatase
Involved in protein transport step at the
Brefeldin A blocks
Hypothetical ORF
Transcription factor (putative)
magnesium ion transporter
Nitrogen
catabolite-regulated
cell-wall
L-asparaginase II
Hypothetical ORF
Hypothetical ORF
Mitochondrial ribosomal protein of the large
subunit
Ribosomal protein (YmL32)
Hypothetical ORF
Hypothetical ORF
Hypothetical ORF; maybe continuous with
YLL052C (AQY2) in some strain
backgrounds
including
Sigma1278b;
functions as an aquaporin in these strains.
RNA-dependent helicase (putative)
Hypothetical ORF
YLL044W
YGR208W
YHR089C
YBL100C
SER2
GAR1
-2.2263
-2.2233
-2.2205
-2.2193
YDR083W
RRP8
-2.2185
YDR041W
RSM10
-2.2182
YOL077C
BRX1
-2.2170
YDR465C
YOR314W
YCR006C
YNL296W
YJR077C
YGR273C
YLR212C
YLR432W
RMT2
TUB4
IMD3
-2.2168
-2.2092
-2.2075
-2.2049
-2.2031
-2.2011
-2.2005
-2.1993
YLR175W
CBF5
-2.1983
YOR310C
NOP58
-2.1980
MIR1
YIL080W
-2.1951
YOR375C
GDH1
-2.1903
YHR093W
AHT1
-2.1871
YLL009C
YOR294W
YOL022C
COX17
RRS1
-2.1802
-2.1801
-2.1772
YKR080W
MTD1
-2.1762
YOR271C
-2.1721
YGR082W
TOM20
-2.1719
YMR193W
MRPL24
-2.1717
Hypothetical ORF
Phosphoserine phosphatase
Small nucleolar RNP protein
Sporulation
Nucleolar protein required for efficient
processing of pre-rRNA at site A2;
methyltransferase homolog
Mitochondrial ribosome small subunit
component
Essential nucleolar protein required for
biogenesis of the 60S ribosomal subunit
Arginine methyltransferase
Hypothetical ORF
Hypothetical ORF
Hypothetical ORF
Product of gene unknown
Hypothetical ORF
Gamma tubulin
IMP dehydrogenase homolog
Major
low
affinity
55
kDa
centromere/microtubule binding protein
U3 snoRNP protein
TyB Gag-Pol protein; proteolytically
processed to make the Gag, RT, PR, and IN
proteins
that
are
required
for
retrotransposition
NADP-specific glutamate dehydrogenase
The AHT1 DNA sequence is upstream of
HXT4 and contains an HXT4 regulatory
element which is a multicopy suppressor of
glucose
transport
defects;
probable
non-functional ORF
Cysteine-rich protein
Regulator for ribosome synthesis
Protein required for cell viability
NAD-dependent
5,10-methylenetetrahydrafolate
dehydrogenase
Hypothetical ORF
20 kDa mitochondrial outer membrane
protein import receptor
Mitochondrial ribosomal protein of the large
subunit
YLR295C
YGL120C
YDR398W
ATP14
PRP43
UTP5
YOR187W
TUF1
YBR291C
YJL010C
CTP1
YPL214C
THI6
YLR406C
RPL31B
YOL109W
ZEO1
YDR347W
MRP1
YIL064W
YPR136C
YNR036C
YPL173W
MRPL40
YIL093C
RSM25
YIR021W
MRS1
YPL124W
SPC29
YHR170W
NMD3
YNL284C
MRPL10
YOL069W
NUF2
YBR268W
MRPL37
YJL125C
GCD14
YPR119W
YOR091W
YCL024W
CLB2
KCC4
-2.1680 ATP synthase subunit h
-2.1659 RNA helicase
-2.1659 U3 snoRNP protein
Translation
elongation
factor
Tu,
-2.1627
mitochondrial
-2.1619 Citrate tranporter
-2.1617 Protein required for cell viability
TMP
-2.1616 pyrophosphorylase|hydroxyethylthiazole
kinase
-2.1614 ribosomal protein L31B (L34B) (YL28)
Peripheral membrane protein of the plasma
membrane that interacts with Mid2p;
-2.1604
regulates the cell integrity pathway mediated
by Pkc1p and Slt2p
-2.1591 37 kDa mitochondrial ribosomal protein
Putative
S-adenosylmethionine-dependent
-2.1591 methyltransferase of the seven beta-strand
family
-2.1587 Hypothetical ORF
-2.1555 Hypothetical ORF
Mitochondrial ribosomal protein of the large
-2.1537
subunit
Mitochondrial ribosome small subunit
-2.1523
component
RNA splicing protein of the mitochondrial
-2.1490
carrier (MCF) family
-2.1489 Spindle pole body component
Factor required for a late assembly step of the
-2.1434
60S subunit
Mitochondrial ribosomal protein of the large
-2.1432
subunit
Spindle pole body protein, required for
chromosome segregation during mitosis; part
-2.1428
of a centromeric complex along with Tid3p,
Spc25p, and Spc24p
Mitochondrial ribosomal protein of the large
-2.1407
subunit
Subunit
of
tRNA(1-methyladenosine)
-2.1401
methyltransferase, along with Gcd10p
-2.1384 B-type cyclin
-2.1381 Hypothetical ORF
-2.1378 S. pombe Nim1 homolog|protein kinase
YIL127C
YPL013C
MRPS16
YER126C
NSA2
YKL191W
DPH2
YDR023W
SES1
YCL063W
VAC17
YHR059W
FYV4
YLR156W
YBL028C
YLR157C-B
YHR149C
YHL009WA
YKR013W
PRY2
YOL125W
YCR019W
MAK32
YOL052C
YNL142W
SPE2
MEP2
YOR335C
ALA1
YDL037C
BSC1
YMR128W
ECM16
-2.1367 Hypothetical ORF
Mitochondrial ribosomal protein of the small
-2.1355
subunit
-2.1349 Ribosome biogenesis
Protein of unknown function, involved in
-2.1317 diphtheria
toxicity
and
diphthamide
biosynthesis, not essential for viability
-2.1307 Serine-tRNA ligase
the vacuole-specific receptor of Myo2p, a
-2.1303
class V myosin
Protein of unknown function, required for
-2.1286
survival upon exposure to K1 killer toxin
Note:
YLR156W,
YLR159W,
and
-2.1241
YLR161W are identical.
-2.1239 Hypothetical ORF
TyB Gag-Pol protein; proteolytically
processed to make the Gag, RT, PR, and IN
-2.1226
proteins
that
are
required
for
retrotransposition
Protein of unknown function found in the bud
-2.1220
tip and bud neck, potential Cdc28p substrate
TyA Gag protein; the main structural
-2.1193
constituent of virus-like particles (VLPs)
Pathogen Related in Sc, contains homology
to the plant PR-1 class of pathogen related
proteins. The protein sequence is over 60%
-2.1167
identical with the Pry2p & Pry3p over 145
resid. PRY1 is >35% identical (50% similar)
to tobacco PR-1c protein.
-2.1132 Hypothetical ORF
Protein necessary for structural stability of
-2.1112 L-A
double-stranded
RNA-containing
particles
-2.1108 S-adenosylmethionine decarboxylase
-2.1078 ammonia transport protein
Cytoplasmic
alanyl-tRNA
synthetase,
required for protein synthesis; point mutation
-2.1076 (cdc64-1 allele) causes cell cycle arrest at G1;
lethality of null mutation is functionally
complemented by human homolog
Bypass of Stop Codon transcript encoded by
-2.1038 this ORF shows a high level of stop codon
bypass
-2.1037 U3 snoRNP protein
YGR151C
YML060W
YDR449C
YHR064C
OGG1
UTP6
SSZ1
-2.1017
-2.1014
-2.0998
-2.0991
YGR103W
NOP7
-2.0944
YDR278C
YNL217W
YLR434C
YBL013W
YML120C
FMT1
NDI1
-2.0939
-2.0935
-2.0920
-2.0913
-2.0909
YGR174C
CBP4
-2.0899
YKL081W
TEF4
-2.0892
YPL211W
NIP7
-2.0861
YGL068W
YCR057C
PWP2
-2.0854
-2.0843
YPR037C
ERV2
-2.0772
DCD1
-2.0766
-2.0761
YLL022C
YHR144C
Q0075
AI5_BET
A
-2.0757
YNL173C
MDG1
-2.0752
YGR251W
-2.0698
YBL045C
COR1
-2.0689
YOR361C
YGR291C
YGR288W
YBL054W
YNL248C
PRT1
RPA49
-2.0684
-2.0656
-2.0643
-2.0635
-2.0611
YLR029C
RPL15A
-2.0604
YJL050W
MTR4
-2.0598
MAL13
Hypothetical ORF
43 kDa 8-oxo-guanine DNA glycosylase
U3 snoRNP protein
HSP70 family
Nucleolar protein involved in rRNA
processing and 60S ribosomal subunit
biogenesis; constituent of several different
pre-ribosomal particles
Hypothetical ORF
Hypothetical ORF
Hypothetical ORF
Methionyl-tRNA transformylase
NADH dehydrogenase (ubiquinone)
Essential for the expression and activity of
ubiquinol-cytochrome c reductase
Translation elongation factor EF-1gamma
Nip7p is required for 60S ribosome subunit
biogenesis
Protein required for cell viability
U3 snoRNP protein
Flavin-linked sulfhydryl oxidase localized to
the endoplasmic reticulum lumen, involved in
disulfide bond formation within the ER
Hat1 Interacting Factor 1
dCMP deaminase
Protein of unknown function, encoded within
an intron of the mitochondrial COX1 gene;
translational initiation codon is predicted to
be ATA rather than ATG
Multicopy suppressor of bem1 mutation, may
be involved in G-protein mediated signal
transduction; binds cruciform DNA
Protein required for cell viability
Coenzyme QH2 cytochrome c reductase 44
kDa core protein subunit
Translation initiation factor eIF3 subunit
Hypothetical ORF
MAL-activator protein
Hypothetical ORF
RNA polymerase A 49 kDa alpha subunit
Ribosomal protein L15A (YL10) (rp15R)
(L13A)
RNA helicase
YAL003W
YDR089W
YGR272C
EFB1
YKL138C
MRPL31
YHR127W
YDR405W
MRP20
YJR047C
ANB1
YNL252C
MRPL17
YGR183C
QCR9
YFR028C
YLR312WA
YPR020W
YJR154W
YKL183W
YDL080C
CDC14
YNL315C
ATP11
YNL029C
YIL083C
KTR5
YPR112C
MRD1
MRPL15
ATP20
LOT5
THI3
YPL257W-B
YPR102C
RPL11A
YGR081C
SLX9
YHR136C
SPL2
-2.0569 Translation elongation factor EF-1beta
-2.0539 Hypothetical ORF
-2.0532 Hypothetical ORF
Mitochondrial ribosomal protein of the large
-2.0515
subunit
(H)igh copy (S)uppressor of (N)34 dominant
negative allele of SEC4. Suppression is very
-2.0475 specific to this allele. It has no affect on the
analogous YPT1 allele. No homology or
known function.
263 amino acid mitochondrial ribosomal
-2.0468 large subunit|similar to L23 family of
ribosomal proteins
Translation
initiation
factor
eIF-5A,
-2.0464
anaerobically expressed form
Mitochondrial ribosomal protein of the large
-2.0451
subunit
Ubiquinol cytochrome c oxidoreductase
-2.0432
complex 7.3 kDa subunit 9
-2.0426 Protein phosphatase
Mitochondrial ribosomal protein of the large
-2.0418
subunit
-2.0416 ATP synthase subunit g homolog
-2.0403 Hypothetical ORF
-2.0398 LOw Temperature responsive
-2.0373 Alpha-ketoisocaproate decarboxylase
Essential for assembly of a functional
-2.0371 F1-ATPase; binds the beta subunit of
F1-ATPase.
-2.0335 Mannosyltransferase (putative)
-2.0322 Homolog to human PPCS
Multiple RNA Binding Domain; essential for
-2.0321
synthesis of the small ribosomal subunit
TyB Gag-Pol protein; proteolytically
processed to make the Gag, RT, PR, and IN
-2.0294
proteins
that
are
required
for
retrotransposition
Ribosomal protein L11A (L16A) (rp39A)
-2.0286
(YL22)
Protein of unknown function; deletion mutant
-2.0274 has synthetic fitness defect with an sgs1
deletion mutant
-2.0272 Protein with similarity to cyclin-dependent
YGL045W
RIM8
-2.0254
YBR202W
CDC47
-2.0248
YMR042W
ARG80
-2.0237
YJL063C
MRPL8
-2.0232
YGL143C
MRF1
-2.0229
YDR225W
HTA1
-2.0225
YHR088W
RPF1
-2.0217
YPR074W-A
YKL143W
-2.0214
LTV1
-2.0211
YOR006C
YDL031W
YEL034W
DBP10
HYP2
-2.0182
-2.0172
-2.0164
YEL050C
RML2
-2.0150
YKL181W
YPL255W
PRS1
BBP1
-2.0105
-2.0083
YGL236C
MTO1
-2.0079
YPL029W
SUV3
-2.0058
YNL022C
YJL168C
a
b
-2.0057
SET2
-2.0026
kinase inhibitors, overproduction suppresses
a plc1 null mutation; green fluorescent
protein (GFP)-fusion protein localizes to the
cytoplasm in a punctate pattern
Regulator of IME2 (RIM) Involved in
proteolytic processing of Rim1p
Component of the hexameric MCM complex,
which is important for priming origins of
DNA replication in G1 and becomes an
active ATP-dependent helicase that promotes
DNA melting and elongation when activated
by Cdc7p-Dbf4p in S-phase
Transcription factor
Mitochondrial ribosomal protein of the large
subunit
Mitochondrial polypeptide chain release
factor
Histone H2A (HTA1 and HTA2 code for
nearly identical proteins)
Protein that localizes to the nucleolus
Hypothetical ORF identified by homology.
See FEBS Letters [2000] 487:31-36.
Protein required for viability at low
temperature
Hypothetical ORF
Dead box protein 10
Translation initiation factor eIF-5A
mitochondrial ribosomal protein L2 of the
large subunit
Ribose-phosphate pyrophosphokinase
Involved in mitotic cell cycle and meiosis
Mitochondrial Translation Optimization;
Strong similarity to E. coli GidA
ATP dependent helicase (putative)
Non-essential protein with similarity to S.
pombe hypothetical protein E349594
Contains SET domain
Genes with expression changes upon treatment with 64 µg of dictamnine per ml.
Fold change refers to expression increases or decreases for upregulated or
downregulated genes, respectively.
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