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Course title
Genetics
Course code
PMB023
Type of course
Lectures
Level of course
Basic course
Year of study
2. year
ECTS
(Number of
credits allocated)
3,5 ECTS
Name of lecturer
Dr. Jasna Puizina, assistant professor
Learning
outcomes and
competences
At the end of the course the learner is expected to know the structure and
organization of genetic material, mechanisms of transmission and regulation of the
genetic information. The learner will know the most important achievements of
applied genetics. The knowledge obtained in this course is important for further
understanding of Molecular biology.
Cell Biology
Prerequisites
Course contents
Recommended
reading
Supplementary
reading
Teaching methods
Assessment
methods
Language of
instruction
Quality assurance
methods
Semester/trimester
4. semester
Genes and chromosomes. Mendel’s laws and chromosomal basis of inheritance.
Sex chromosomes and sex-linked inheritance. Interactions between alleles and
genes: incomplete dominance, codominance, lethal alleles, epistasis, suppression,
penetrance. Linkage, meiotic recombination and mapping in Eukaryotes and
Prokaryotes. Cytogenetics: variations in chromosome structure and number,
evolution of the genome. Molecular genetics: structure of DNA, replication,
transcription, translation. Organization of the human genome: unique sequences,
introns, egzons, alternative splicing, gene duplications, gene families,
pseudogenes, repetitive sequences, movable genetic elements. Human genome
project. Control of gene expression, chromatin modification, parental imprinting.
Non-mendelian inheritance. Quantitative inheritance. Population genetics. Ethic
dilemmas in genetics: eugenetics, privacy of genetic information, loss of genetic
variability.
1. Tamarin, R.H: Principles of Genetics. Šesto izdanje. WCB, McGraw-Hill,
1999.
2. Lewin, B., Genes VIII. Osmo izdanje. Pearson Prentice Hall, Pearson
Education, 2004.
3. Cox, T.M., Sinclair, J.: Molekularna biologija u medicini. Medicinska naklada,
Zagreb, 2000.
4. Lj. Zergollern i suradnici: Humana genetika. Medicinska naklada, Zagreb,
1994.
Lectures (30 hours). Audiovisual equipment and computer are used in teaching.
Students participate in discussion and asking questions.
Two partial tests during attending the lectures. If the learner has been successfully
passed both partial tests, he is free of written exam. Successfully passed exam form
Practical form Genetics is prerequisite for taking the exam from Genetics.
Examination is oral and written.
Croatian and English.
Student’s questionnaires.