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SBI4U FINAL EXAM REVIEW COMPREHENSIVE LIST OF MAJOR CONCEPTS and TERMS June 2014 UNIT 1 Organelles -know the role/function Nucleus, nucleolus, smooth/rough endoplasmic reticulum, golgi apparatus/body, lysosome, perioxisome, mitochondria, ribosome, cytoplasm, cell membrane, cell wall, central vacuole, vesicle, cytoskeleton, microfilaments Cell Membrane and Fluid mosaic model, Transport Hypertonic, hypotonic, isotonic, osmosis, diffusion, facilitated diffusion, protein channel/carrier, active transport pump, endocytosis, exocytosis Chemical Fundamentals covalent bonds, hydrogen bonds, polar, non-polar, hydrophobic, hydrophilic Functional Groups Hydroxyl, carboxyl, carbonyl, ketone, aldehyde, amino, sulfhydryl, phosphate group Types of Reactions Condensation / Dehydration synthesis, hydrolysis, anabolic, catabolic, redox, oxidation, reduction, oxidizing agent, reducing agent, redox in biological systems (covalent molecules), Macro-molecules -definitions -structure -functional groups -properties -diagrams -function -examples Macromolecule carbohydrate, monosaccharide, glucose, isomer, disaccharide, oligosaccharide, polysaccharide, amylose, amylopectin, cellulose, starch, glycogen, chitin, glycosidic linkage lipids, fats, phospholipids, steroids, waxes, saturated, unsaturated, hydrogenation, ester linkage protein, amino acids, peptide bonds, conformation, globular proteins, amino terminus, carboxy terminus, alpha helix, beta-pleated sheets, disulfide bridges, side chain interactions, polypeptide, denaturation nucleic acids, nucleotide, glycosyl bond, hydrogen bonds, phosphodiester bonds, DNA, RNA, examples of other nucleotides Enzymes Enzymes, substrate, reactant, product, active site, induced-fit model, enzyme-substrate complex, allosteric sites, activator, competitive inhibitors, non-competitive inhibitors, allosteric inhibitors UNIT 2 Energy Metabolism, catabolic, anabolic, activation energy, potential energy, free energy, ATP Cellular Respiration Cellular respiration, oxygen availability, substrate level phosphorylation, electron carriers, ATP Glycolysis Glycolysis, glucose activation/priming, sugar splitting, oxidation, substrate-level phosphorylation, glyceraldehyde 3-phosphate, DHAP, pyruvate, energy yield, anaerobic, F1,6BP, 1-3BPG, PEP Mitochondria Eukaryotic, cristae, matrix, intermembrane space, outer membrane, inner membrane Pyruvate Oxidation Decarboxylation, oxidation, co-enzyme A, acetyl co-enzyme A, coenzyme, products Kreb's Cycle Cycle, oxaloacetate, citric acid, succinate, fumerate, malate, succinyl-CoA, alpha ketoglutarate, isocitrate, GTP, coenzyme A, yield of: ATP, CO2, NADH, FADH2 ETC Cytochromes, NADH dehydrogenase, ubiquinone, proton pumps, proton gradient, inner mitochondrial membrane, intermembrane space, free energy, protons, electrons, oxygen, water, chemiosmosis, proton motive force, ATP synthase, matrix, oxidative phosphorylation, energy yield per NADH, FADH2, overall Anaerobic Respiration Fermentation, lactic acid fermentation, ethanol fermentation, oxygen debt, acetylaldehyde, lactic acid, role of NADH, anaerobic Photosynthesis Chloroplast, outer membrane, inner membrane, stroma, thylakoids, lamellae, grana, chlorophyll, thylakoid membrane, thylakoid lumen, intermembrane space, action spectrum, absorption spectrum, chlorophyll a, chlorophyll b, accessory pigments, saturation level, rate of photosynthesis with varying amounts of light, CO2 Light Reactions Light reactions, photoexcitation, electron transport, chemiosmosis, non-cyclic electron flow, cyclic electron flow ground state, excitation, antenna complex, reaction centre, photosystems I and II, Z protein, photolysis, photophosphorylation, ETC, proton gradient, NADP reductase Calvin Cycle Calvin cycle, carbon fixation, reduction reactions, regeneration of RuBP, RuBP, rubisco, G3P, starch Bioremediation Bioremediation UNIT 3 DNA History Miescher, Griffith, Avery/McCarty/MacLeod, Chargraff, Hershey/Chase, Franklin, Waston/Crick, , transformation, nuclein, pus, virulent, non-virulent, radioisotopes, X-ray diffraction, bacteriophage, DNA Structure Nucleotide, deoxyribose sugar, phosphate group, nitrogenous base, phosphodiester bond, glycosyl bond, hydrogen bonds, purine, pyrimidine, complementary base pairing, antiparallel, 5', 3' DNA Replication Meselsson and Stahl, semiconservative, Origin of replication, ORC, DNA helicase, Topoisomerase II (DNA gyrase), DNA polymerase III/I, RNA primers, primase, exonuclease, SSBs, anneal, template, replication fork, replication bubble, lagging strand, leading strand, Okazaki fragments, DNA ligase Protein Synthesis: Transcription RNA polymerase, promoter, upstream, template strand, coding strand, stop sequence, capping, poly A tail, introns, exons, spliceosomes, mRNA, primary transcript, poly-A polymerase Protein Synthesis: Translation rRNA, ribosomes, subunits, AUG, Acceptor site, Peptide site, catalytic site, exit site, tRNA, codon, stop codon, release factor protein, anticodon, methionine, polypeptide Gene Regulation Transcription factors, operon, operator, promoter, regulator, structural genes, repressor, inducer, lac operon on/off Biotechnology Restriction endonucleases, gel electrophoresis, recombinant DNA, plasmid, transformation, vector, host cell Mutations Point, deletion, insertion, substitution, missense, translocation, silent, frameshift, chromosomal duplication, inversion, deletion, translocation, UNIT 4 Homeostasis Homeostasis/dynamic equilibrium, negative/positive feedback, effector, regulator, coordinating centre, sensor, monitor, oxytocin, thermoregulation, feedback loops, hypothalamus, evaporative cooling Endocrine System Endocrine, hormones, target organs/cells/tissues, receptor, steroid hormone, protein hormone, hormone-receptor complex, pituitary gland, anterior/posterior lobe, hypothalamus, releasing factors Blood sugar levels, pancreas, islets of Langerhans, alpha cells, beta cells, insulin, glucagon, glycogen, liver/muscles, feedback loop, diabetes types and symptoms Testes, seminiferous tubules, interstitial cells, Sertoli cells, testosterone, sperm, inhibin, GnRH, LH, FSH, feedback loop Ovaries, follicles, follicular cells, ova/ovum, corpus luteum, estrogen, progesterone, ovulation, menstruation, endometrium lining, follicular phase, luteal phase, flow phase, feedback loop Excretory System Deamination, ammonia, urea, uric acid, kidney, renal cortex, renal medulla, renal pelvis, nephron, afferent arteriole, efferent arteriole, peritubular capillaries, Bowman's capsule, proximal tubule, distal tubule, loop of Henle, collecting ducts, urethra, urinary sphincter, urinary bladder filtration, reabsorption (solutes and water, active and passive/osmosis), secretion, Na+ pumps, threshold levels water balance, ADH, osmoreceptors, hypothalamus, osmotic pressure diabetes insipidus, Bright’s disease, kidney stones Nervous System CNS, PNS, neuron, sensory neuron, glial cells, motor neuron, interneuron, dendrites, axon, myelin sheath, Schwann cells, nodes of Ranvier, neurilemma, spinal cord injury, reflex arc, grey matter, white matter action potential, resting potential, ion gates, depolarization, sodium-potassium pump, repolarization, refractory period, threshold level, all-or-none response, hyperpolarized synapse, neurotransmitter, presynaptic neuron, postsynaptic neuron, acetylcholine, cholinesterase, inhibitory, excitatory, summation UNIT 5 Population Characteristics Population size, density, crude density, ecological density, uniform dispersion, clumped dispersion, random dispersion, sampling techniques, mark-recapture method, quadrat sampling Measuring Population Change Carrying capacity, natality, mortality, immigration, emigration, survivorship curves, population change (%), biotic potential, fecundity, fertility, open population, closed population, Geometrical Exponential, Logistic Factors Affecting Population Change Density-dependent factors, intraspecific competition, predation, Allee effect, inbreeding depression, minimum viable population size, density independent factors, Change affects entire hierarchy of ecosystem Interactions within Communities Community, ecological niche, interspecific competition, symbiosis, parasitism, mutualism, commensalism Interference competition, exploitative competition, resource partitioning, predator-prey relationships, defense mechanisms, morphological, chemical, passive, active, mimicry (Batesian/Mullerian) Food Industry Industrialization, agriculture, packaging, transportation, food miles, waste, distribution, consumption, fossil fuels (including fertilizers, pesticides), water efficiency Ecological Footprint / LPI Ecological footprint, living planet index, sustainability