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Subject (Materia) GENETICS Faculty (Facoltà) Scienze MM.FF.NN. Course od Study (Corso Marine Biology and Ecology di Laurea) Teacher (Docente) Dott.ssa Carla Lo Passo Contacts Address (indirizzo): Dip. di Scienze Microbiologiche, Genetiche e Molecolari - (Coordinate) Contrada Sperone - Salita Papardo, 98166 Messina Phone (telefono): 0039 090 6765203 Fax: 0039 090 392733 E-Mail: [email protected] Workload 56 (Durata del Corso in ore) Credits (Crediti CFU) 4+1 Pre-requisites none (Pre requisiti) Course Description (Descrizione del Corso) Mendelian Genetics 6h theory Mendel’s laws, Elements of Mendelian inheritance in man, family trees Exercises 2h practice Chromosome basis of inheritance 6h theory Chromosome theory of inheritance, sex chromosomes, sex linked inheritance, X chromosomes non-disjunction, sex determination Exercises 2h practice Extensions of Mendelian genetic analysis 4h theory Multiple alleles, modification of dominance relationships, lethal genes Exercises 2h practice Linkage, crossing-over and gene mapping in Eukaryotes 6h theory Genes linkage, gene mapping on chromosomes: gene mapping techniques, tetradi analysis Exercises 2h practice Genetic analysis of bacteria Transformation, Conjugation, transduction 4h theory Plasmid DNA mini preparation Transformation of E.coli by electroporation 2h practice 2h practice Regulation of gene expression in bacteria Lactose operon, tryptophan operon 4h theory Exercises 2h practice Evolution of genetic material 4h theory Gene mutations, chromosomes mutations: structural changes and alteration of chromosomes number Population Genetics 6h theory Genotypic frequencies, allele frequencies, Hardy-Weinberg Principle, changes in allelic frequencies: mutation, genetic drift, migration and natural selection Exercises Structure of the Written (Scritto) X 2h practice Oral (Orale) X assessment (Modalità dell’esame) Bibliography (Testi adottati) Further information (Note) P.J. Russell “Fondamenti di Genetica”, EdiSES.