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Course
#
N331
Credit
Hours
3
hours
Lecture Outline
Time
Methodology
Evaluation
Methods
Shock
2 hours
Case Studies
Critical Thinking
Scenarios
Small group
activities
Readings in texts
and journals
Utilization of:
Research Articles,
Resources, CAI=s,
Videos
Utilization of
computer access,
internet, e-mail
Quizzes
Grading in the
course will consist
of the following:
Exam I
Exam II
Exam III
Activity Points
Final
Types of Shock
Circulatory shock
Hypovolemic shock
Obstructive shock
Distributive shock
Neurogenic shock
Anaphylactic shock
Septic shock
Complications of Shock
Acute Respiratory Distress
Syndrome
Acute Renal Failure
Gastrointestinal Complications
Disseminated Intravascular
Coagulation
Multiple Organ
Dysfunction
Drug therapy for shock:
beta adrenergic agonists - review
dopamine - review
isoproterenol - review
Endocrine Regulation
General Aspects of Altered Endocrine Function
Hypofunction and Hyperfunction
Primary, Secondary and Tertiary Disorders
Pituitary and Growth Hormone Disorders
Hypopituitarism
Growth and Growth Hormone Disorders
6 hours
50 po
50 po
50 po
15 po
80 po
Drugs affecting Pituitary
Thyroid Disorders
Control of Thyroid Function
Alterations in Thyroid Function
Hypothroidism
Hyperthryroidism
Drugs affecting Parathyroid and Thyroid gland
Parathyroid Hormone Disorders
Hypoparthyroidism
Hyperparathyroidism
Disorders of Adrenal Cortical Function
Control of Adrenal Cortical Function
Adrenal Cortical Insufficiency
Cushing’s Syndrome
Drugs affecting the Adrenal Cortex
Androgens
Diabetes Mellitus
Energy Metabolism
Glucose, Fat, and Protein
Metabolism
Hormonal Control of Blood
Glucose
Disease Mellitus
Classification and Etiology
Manifestations of Diabetes
Diagnostic Methods
Diabetes Management
Acute Complications
Chronic Complications
Hyper/hypoglycemic Agents
Immune System
Immunization
Immune Response
Inflammation, Tissue Repair, And Fever
The inflammatory response
Acute Inflammation
Chronic Inflammation
Local Manifestations of Inflammation
Systemic Manifestations of Inflammation
Regeneration
Connective Tissue Repair
Factors That affect Wound Healing
Temperature Regulation and Fever
Antiinflammatory Agents
Alterations in the Immune Response
Allergic and hypersensitivity disorders
Type I, IgE Mediated Disorders
Type II, Antibody-Mediated Cytotoxic
Type III, Immune-Complex Disorders
Type IV, Cell-Mediated Hypersensitivity
Disorders
Latex Allergy
Transplantation Immunopathology
Host-Versus-Graft Disease
Grant –VersusHost Disease
Immunologic Tolerance
Immunosuppressent Agents
Mechanisms of Autoimmune Disease
8 hours
Acquired Immunodeficiency Syndrome
Antiviral agents
Rheumatic Disorders
Drugs to treat Rheumatic Disorders
Alterations in Cell Growth and Replication: Neoplasia
Concepts of Cell Growth
The Cell Cycle
Cell Proliferation
Cell Differentiation
Benign vs. Malignant
Carcinogenesis and Causes and Cancer
Diagnosis and Staging
Diagnosis and Treatment
Anticancer Agents
Immunosuppressant
Colony Stimulating Factors
Alterations of WBCs
Neutropenia
Malignant Lymphomas
Leukemia
Multiple Myeloma
3 hours
Altered Skeletal Function
Injury and Trauma of Musculoskeletal
Soft Tissue Injuries
Joint Injuries
Fractures
Bone Infections
Gout
Antigout agents
Metabolic Bone Disease
Osteopenia
2 hours
Osteoporesis
Drugs affecting Calcium levels and Bone
Mineralization
Osteomalacia
Paget’s disease
Osteopenia
Osteoporesis
Osteomalacia
Paget’s disease
Bone Infections
Neoplasms
Hematological Function/Oxygen Transport
Alterations in Red Blood Cells
RBC production
RBC Destruction
RBC Metabolism and Hemoglobin
Oxidation
Lab tests
Anemia
Blood Loss Anemia
Hemolytic Anemia
Agents for Anemia
Anemias of Deficient RBC Production
Polycythemia
Alteration in Hemostasis and Blood Coagulation
Mechanisms of Hemostasis
Blood Coagulation
Clot Retraction
Clot Dissolution
Hypercoagulability States
Increased Platelet Function
Increased Clotting Activity
4.5 hours
Agents for Coagulation
Bleeding Disorders
Platelet Defects
Coagulation Defects
Disseminated Intravascular Coagulation
Vascular Disorders
Hematopoietic Agents
Alterations in the Gastrointestinal System
Structure and Function of the GI system
Anorexia, Nausea, and Vomiting
Antiemetic Agents
Alterations in GI Function
Dysphagia
Gastroesophageal Reflux Disease
Disorders of the stomach
Gastric Mucosal Barrier
Gastritis
Ulcer Disease
Peptic Ulcer
Agents for Peptic Ulcer Agents
Zollinger-Ellison Syndrome
Disorders of the Small and Large Intestines
Irritable Bowel Syndrome
Crohn’s/Ulcerative Colitis Disease
Agents for Inflammatory Bowel Disease
Infectious Colitis
Diverticular Disease
Appendicitis
Alterations in Intestinal Motility
Intestinal Obstruction
Peritonitis Diarrhea
Constipation
Laxatives
3.5
hours
Diarrhea
Antidiarrheal agents
Alterations in Intestinal
Absorption
Neoplasms
Drugs for Obesity
Alterations in Hepatobiliary Function
The liver and hepatobiliary system
Metabolic Functions of the Liver
Bile Production and Cholestasis
Jaundice
Neonatal hyperbilirubinemia
Tests of Hepatobiliary Function
Disorders of the Liver
Hepatitis
Drugs for Hepatitis
Intrahepatic Biliary Disorders
Alcohol Induced Liver Disease
Cirrhosis, Portal Hypertension, and Liver
Failure
Cancer of the Liver
Cholelithiasis and Cholecystitis
Disorders of the Exocrine Pancreas
Acute Pancreatitis
Chronic Pancreatitis
1.5 hours
Pain Management and Headaches
Narcotic and OTC Analgesics
Acetaminophen
1.5 hour
Anti-migraine agents
Narcotic and non-narcotic analgesics
Cancer pain
Local anesthesia
Alterations in the Nervous System
The Spinal Cord and Brain
Alterations in Brain Function
Brain Injury
Mechanisms of Injury
Increased Intracranial Volume and Pressure
Traumatic Head and Brain Injury
Manifestations of Global Brain Injury
Brain Death
Persistent Vegetative State
Cerebrovascular disease
Cerebral Circulation
Stroke
Infections and Neoplasms
Infections
Neoplasms
Seizure Disorders
Classification
Diagnosis and Treatment
Generalized Convulsions Status Epilepticus
Drugs for Epilepsy
6.0 hours
Dementias
Drugs for Alzheimer’s Disease
Sedative-Hypnotic Drugs
Management of Anxiety Disorders
Anxiety
Alterations in Neuromuscular Function
The organization and control of motor function
Spinal Reflexes
Disorders of Muscle Tone and Movement
Skeletal Muscle and Peripheral Nerve Disorders
Muscular Dystrophy
Neuromuscular Junction Disorder
Peripheral Nerve Disorder
Back Pain and Intervertebral Disk Injury
Basal Ganglia and Cerebellum Disorders
Parkinson’s Disease
Drugs for Parkinson's Disease
Cerebellar Dysfunction
Upper and Lower Motoneuron Disorders
Amyotrophic Lateral Sclerosis
Multiple Sclerosis
Spinal Cord Injury
Types and Classifications of Spinal Cord
Injury
Disruption of Functional Abilities
Drugs for Muscle Spasm and Spasticity
Based on 38 hours – some weeks have 2 hour classes due to 1) syllabus review 2) test days