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Version: 1
Revision Date: 08/04/2016
Anti-Parathyroid Hormone (PTH) Antibody
Catalog# / Size
924704 / 100 µl
Clone
Poly29247 (See other available formats)
Other Names
PTH, Preproparathyroid Hormone, Parathyrin
Isotype
Rabbit Polyclonal IgG
Ave. Rating
★★★★★ 0 reviews
Description
Parathyroid hormone (PTH) is secreted by the parathyroid glands as a
preprotein that is protealytically processed to generate a protein that binds
to the PTH receptor to increase the concentration of calcium and phosphate
in the blood.
IHC staining of anti-Parathyroid Hormone
(PTH) antibody (Poly292470) on formalinfixed paraffin-embedded human parathyroid
tissue. The tissue was incubated with the
primary antibody for 20 minutes at room
temperature at 1:1000 dilution. Antigen
retrieval is not required. BioLegend's Ultra
Streptavidin (USA) HRP Detection Kit was
used for detection, followed by
counterstaining with hematoxylin.
See high resolution
IHC-P data...
Immunogen
PTH antibody was raised in rabbit using hPTH-44-68-TBG.
Storage & Handling
Store frozen (-20°C); shipped in blue ice.
Application
IHC-P - Quality tested
Recommended Usage
Each lot of this antibody is quality control tested by formalin-fixed paraffin-embedded
immunohistochemical staining. The optimal working dilution should be determined for each
specific assay condition.
IHC: 1:500 - 1:1000
Application Notes
The BioLegend anti-Parathyroid Hormone (PTH) polyclonal antibody reacts with parathyroid
hormone secreted by the chief cells of the normal parathyroid gland.
Antigen Details
Structure
PTH is a 115 amino acid protein with a molecular mass of 13 kD.
Distribution
Tissue distribution: thyroid and parathyroid.
Cellular distribution: extracellular, cytosol, and plasma membrane.
Function
PTH elevates calcium level by dissolving the salts in bone and preventing their renal excretion.
Ligand Receptor
PTH receptor.
Cross
Human, Rat Cross-Reactivity: Dog
Antigen References
1. Pekkarinen T, et al. 2010. Clin. Endocrinol. 72(4):455.
Gene ID
5741
UniProt
View information about Parathyroid Hormone on UniProt.org
Documentation
Technical data sheet
Certificate of Analysis
Safety Data Sheet
Related Protocols
Immunohistochemistry Protocol for Paraffin-Embedded Sections
Related FAQs
There are no FAQs for this product.
Related Categories
Antibodies and More > Immunopathology Products >
Antibodies and More > Cell Biology > Antigens A-Z > Parathyroid Hormone (PTH) >
Antibodies and More > Cell Biology > Growth Factors/Growth Factor Receptors > Parathyroid Hormone (PTH) >
For research use only. Not for diagnostic use. Not for resale. BioLegend will not be held responsible for patent infringement or
other violations that may occur with the use of our products.
*These products may be covered by one or more Limited Use Label Licenses (see the BioLegend Catalog or our website,
www.biolegend.com/ordering#license). BioLegend products may not be transferred to third parties, resold, modified for resale, or
used to manufacture commercial products, reverse engineer functionally similar materials, or to provide a service to third parties
without written approval of BioLegend. By use of these products you accept the terms and conditions of all applicable Limited
Use Label Licenses. Unless otherwise indicated, these products are for research use only and are not intended for human or
animal diagnostic, therapeutic or commercial use.
BioLegend Inc., 9727 Pacific Heights Blvd, San Diego, CA 92121 www.biolegend.com
Toll-Free Phone: 1-877-Bio-Legend (246-5343) Phone: (858) 768-5800 Fax: (877) 455-9587