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Table S2. Most abundant transcripts (according to signal intensity of the array) in EVs derived from RH Symbol ALB* Entrez Gene Name Rup2 COX1 (includes EG:140539) LOC257642 ND1 (includes EG:140531) CYTB (includes EG:140512) ND2 (includes EG:140532) COX2 (includes EG:140540) TTR NADH dehydrogenase, subunit 1 (complex I) TF transferrin APOC3 apolipoprotein C-III ND3 (includes EG:140533) SERPINA1 NADH dehydrogenase, subunit 3 (complex I) HP FTH1 (includes EG:14319) MGST1* GC Type(s) transporter Intensity 214137 urinary protein 2 cytochrome c oxidase subunit I Location Extracellular Space unknown Cytoplasm other enzyme 111988 98669 rRNA promoter binding protein Nucleus 66042 Cytoplasm transcription regulator enzyme cytochrome b Cytoplasm enzyme 57777 MTND2 Cytoplasm enzyme 52592 cytochrome c oxidase subunit II Cytoplasm enzyme 46004 Extracellular Space Extracellular Space Extracellular Space Cytoplasm transporter 40923 transporter 39487 transporter 33694 enzyme 31683 Extracellular Space other 30051 Extracellular Space Cytoplasm peptidase 21798 enzyme 19823 Cytoplasm enzyme 19752 Extracellular Space Extracellular Space Extracellular Space Extracellular Space Cytoplasm Cytoplasm Cytoplasm Extracellular transporter 18975 transporter 16493 transporter 12633 other 12556 other other transporter transporter 11770 10898 10801 10595 albumin transthyretin serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 haptoglobin ferritin, heavy polypeptide 1 microsomal glutathione Stransferase 1 group-specific component (vitamin D binding protein) APOC1* apolipoprotein C-I RBP4 retinol binding protein 4, plasma AHSG alpha-2-HS-glycoprotein RPS27* RPS19 FABP1* APOH ribosomal protein S27 ribosomal protein S19 fatty acid binding protein 1, liver apolipoprotein H (beta-2- 65450 RPL41 CA3 RPL23 RPS14 glycoprotein I) ribosomal protein L41 carbonic anhydrase III, muscle specific ribosomal protein L23 ribosomal protein S14 TMSB10/TMSB4X thymosin beta 4, X-linked apolipoprotein E APOE Space Cytoplasm Cytoplasm Cytoplasm Cytoplasm Cytoplasm Extracellular Space Cytoplasm Cytoplasm Cytoplasm RPS29 RPS2 TPT1 (includes EG:100043703) RPS18 RPS23 ribosomal protein S29 ribosomal protein S2 tumor protein, translationallycontrolled 1 ribosomal protein S18 ribosomal protein S23 Cytoplasm Cytoplasm RPL27A ACTB Gm6402 ribosomal protein L27a actin, beta ribosomal protein S17 pseudogene alpha-1-microglobulin/bikunin precursor Nucleus Cytoplasm Cytoplasm AMBP Rpl9 APOA2 ribosomal protein L9 apolipoprotein A-II B2M beta-2-microglobulin RPS8 RPL26 SEPP1 ribosomal protein S8 ribosomal protein L26 selenoprotein P, plasma, 1 LOC299282 Serine protease inhibitor FTL Eef1a1 ferritin, light polypeptide eukaryotic translation elongation factor 1 alpha 1 RPS12 ribosomal protein S12 other enzyme 10508 10489 other translation regulator other transporter 10152 10043 other other other 9529 9453 9233 other translation regulator other other other 8619 8592 Extracellular transporter Space Nucleus other Extracellular transporter Space Plasma transmembrane Membrane receptor Cytoplasm other Cytoplasm other Extracellular other Space Extracellular other Space Cytoplasm enzyme Cytoplasm translation regulator Cytoplasm other * Genes employed in the validation of Supplemental Figure 1B 9719 9623 8408 8293 8123 8113 8059 7758 7723 7700 7615 7505 7444 7434 7275 7064
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